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Abstracts tagged "Rheumatoid arthritis (RA)"

  • Abstract Number: 494 • 2019 ACR/ARP Annual Meeting

    Clinical and Biomarker Factor Associations with Symptoms and Future Development of RA: TIP-RA Collective

    Kevin Deane1, Sunil Nagpal 2, V. Michael Holers 3, Gary Firestein 4, David Boyle 5, Jennifer Seifert 3, Jane Buckner 6, Eddie James 6, Laurakay Moss 7, Saman Barzideh 7, Sylvia Posso 6, William Robinson 8, Kristen Polinski 7, Roger Gilmore 7, Frédéric Baribaud 9, Navin Rao 2 and George Vratsanos 10, 1University of Colorado Denver, Division of Rheumatology, Aurora, CO, USA, Aurora, CO, 2Janssen R&D, Spring House, PA, 3University of Colorado Denver, Division of Rheumatology, Aurora, CO, USA, Denver, 4University of California, San Diego, San Diego, 5University of California, San Diego, San Diego, CA, 6Benaroya Research Institute, Seattle, WA, 7University of Colorado Denver, Aurora, CO, 8Stanford University, Palo Alto, CA, 9Janssen Research & Development, LLC, Spring House, PA, 10JNJ, Raritan, NJ

    Background/Purpose: The Targeting Immune Responses for Prevention of RA (TIP-RA) Collaborative prospectively studies individuals at high risk for developing RA because of serum ACPA positivity…
  • Abstract Number: 537 • 2019 ACR/ARP Annual Meeting

    Efficacy and Safety Results from a Randomized Double-Blind Study That Compared the Proposed Biosimilar ABP 798 with Rituximab in Subjects with Moderate to Severe RA

    Gerd Burmester1, Edit Drescher 2, Pawel Hrycaj 3, David Chien 4, Zhiying Pan 4 and Stanley Cohen 5, 1Charité—University Medicine Berlin, Berlin, Germany, 22Veszprém Csolnoky Ferenc County Hospital, Veszprém, Hungary, 3Koscian Municipal Hospital, Koscian, Poland, 4Amgen, Thousand Oaks, CA, 5Metroplex Clinical Research Center, Dallas, TX

    Background/Purpose: ABP 798 is being developed as a biosimilar to rituximab, a CD20-directed cytolytic antibody that is approved in the US and EU for treatment…
  • Abstract Number: 842 • 2019 ACR/ARP Annual Meeting

    Mortality Ratio and Risk Factors in CT Confirmed Rheumatoid Arthritis Related Lung Disease: UIP, Pleural Effusion and the Time of Diagnosis of Rheumatoid Arthritis – Lung Disease

    Mustafa Ekici 1, Alper Sarı 2, Yusuf Baytar 3, Ertugrul Cagri Bolek 2, Berkan Armagan 4, Emre Bilgin 2, Bayram Farisoğulları 2, Omer Karadag 5, Ali İhsan Ertenli 2, Sedat Kiraz 5, Şule Apras Bilgen 5, Levent Kilic 5, Ali Akdoğan 2, Gamze durhan 3, Macit arıyürek 3 and Umut Kalyoncu6, 1Hacettepe University, Faculty of Medicine, Department of Internal Medicine, Ankara, Turkey, 2Hacettepe University Vasculitis Centre, Ankara, Turkey, Ankara, Turkey, 3Hacettepe University, Faculty of Medicine, Department of Radiology, Ankara, Turkey, 4Department of Internal Medicine, Hacettepe University, Faculty of Medicine, Ankara, Turkey., Ankara, Turkey, 5Hacettepe University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, ankara, Turkey, 6Hacettepe University Department of Rheumatology, Ankara, Turkey

    Background/Purpose: The frequency of pulmonary involvement in rheumatoid arthritis varies between 7-35%. The most important cause of death in RA patients is lung disease in…
  • Abstract Number: 960 • 2019 ACR/ARP Annual Meeting

    Autoantibodies in Rheumatoid Arthritis Target Citrulline-Containing and Native Epitopes from Conformationally Disordered Regions of Proteins

    Zihao Zheng 1, Lauren Fahmy 1, Alan Bridges 2, Michael Newton 1 and Miriam Shelef1, 1University of Wisconsin - Madison, Madison, 2William S. Middleton Memorial Veterans Hospital, Madison

    Background/Purpose: Anti-citrullinated protein antibodies (ACPAs) and rheumatoid factor (RF) are the main diagnostic and pathologic autoantibodies in rheumatoid arthritis. However, autoantibodies develop against proteins with…
  • Abstract Number: 1172 • 2019 ACR/ARP Annual Meeting

    The Relationship Between Subclinical Inflammation and Bone Damage in Patients with Rheumatoid Arthritis Using Multimodality Imaging

    Scott Brunet 1, Peter Salat 2, Glen Hazlewood 3, Klaus Engelke 4, Cheryl Barnabe 3 and Sarah Manske3, 1University of Calgary, Calgary, Canada, 2University of Calgary, Calary, Canada, 3University of Calgary, Calgary, AB, Canada, 4Erlangen University Hospital, Department of Medicine, Erlangen, Germany

    Background/Purpose: Many RA patients in clinical remission have evidence of bone marrow edema (BME) on magnetic resonance imaging (MRI), with radiographic bone damage progression appearing…
  • Abstract Number: 1344 • 2019 ACR/ARP Annual Meeting

    Increased High Molecular Weight Adiponectin and Lean Mass During Tocilizumab Treatment in Patients with Rheumatoid Arthritis: A 12 Month Multicenter Study

    Eric Toussirot1, Hubert Marotte 2, denis Mulleman 3, gregoire Cormier 4, fabienne Coury-Lucas 5, Philippe Gaudin 6, Emmanuelle Dernis 7, christine bonnet 8, richard damade 9, jean-luc Grauer 10, Tassadit Ait Abdesselam 11, caroline Karras 12, frederic Liote 13, Pascal Hilliquin 14, antoinette sacchi 15, Jean-Marie Berthelot 16, marc puyraveau 1 and gilles dumoulin 1, 1University Hospital, Besancon, France, 2University Hospital, St Etienne, France, 3University hospital, Tours, France, 4CHD Vendée, La Roche sur Yon, France, 5University Hospital, Lyon, France, 6Rheumatology Department, CHU Grenoble Alpes Hôpital Sud and GREPI - Université Grenoble Alpes, EA7408, Grenoble - Echirolles, France, 7Rheumatology Department, Le Mans Central Hospital, Le Mans, France, 8University Hospital, Limoges, France, 9Centre Hospitalier, Chartres, France, 10Centre Hopsitalier, Montelimar, France, 11Centre Hospitalier, Meaux, France, 12Hôpital Saint Joseph, Marseille, France, 13AP-HP, Paris, France, 14Centre Hospitalier, Corbeil Essones, France, 15Centre Hospitalier, Mantes la Jolie, France, 16University Hospital, Nantes, France

    Background/Purpose: Patients with rheumatoid arthritis (RA) have an increased risk of cardiovascular (CV) diseases. Dyslipidemia is a known adverse reaction to tocilizumab (TCZ). TNFa blockade…
  • Abstract Number: 1371 • 2019 ACR/ARP Annual Meeting

    Create an Algorithm of Outcome Forecasting and Decision Making for RA Treatment: Data Mining and Machine Learning via the Smart System of Disease Management (SSDM)

    Rong Mu1, Chun Li 2, Jing Yang 3, Xiaohan Wang 4, Bin Wu 5, Fengxiao Zhang 6, Yong Wang 7, Li Qin 8, Cundong Mi 9, Huifang Guo 10, Wei Wei 11, Wei Liu 12, Qingchun Huang 13, Jing Lu 14, Yang Liu 15, Huiling Li 16, Bing Wu 17, Hui Xiao 18, Yuhua Jia 19 and Fei Xiao 20, 1People's Hospital, Beijing University Medical School, Beijing, China (People's Republic), 2People's Hospital, Beijing University Medical School, Beijing, Beijing, China (People's Republic), 3Central Hospital of MianYang, Mianyang, Sichuan, China (People's Republic), 4Anyang district hospital, Fuyang, Hainan, China (People's Republic), 5Chongqing Hospital of Traditional Chinese Medicine, Chongqing, Chongqing, China (People's Republic), 6Hebei General Hospital, Shijiazhuang, Hebei, China (People's Republic), 7The first Hospital Affiliated to AMU (Southernwest Hospital), Chongqing, China (People's Republic), 8The No.3 People’s Hospital of HuZhou City, Huzhou, Zhejiang, China (People's Republic), 9The Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China (People's Republic), 10The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China (People's Republic), 11Tianjin Medical University General Hospital, Tianjin, Tianjin, China (People's Republic), 12First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China (People's Republic), 13The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China (People's Republic), 14First Affiliated Hospital of China Medical University, Shenyang, Liaoning, China (People's Republic), 15Affiliated Hospital of Inner Mongolia Medical University, Huhehaote, Nei Mongol, China (People's Republic), 16Hubei Hospital of Traditional Chinese Medicine, Wuhan, Hubei, China (People's Republic), 17Shanghai Gothic Internet Technology Co., Ltd, Shanghai, China (People's Republic), 18Shanghai Gothic Internet Technology Co., Ltd, shanghai, Shanghai, China (People's Republic), 19Shanghai Gothic Internet Technology Co., Ltd., Shanghai, Shanghai, China (People's Republic), 20Shanghai Gothic Internet Technology Co., Ltd., shanghai, China (People's Republic)

    Background/Purpose: Daily health care deals with a wide spectrum of RA patients from statuses of remission (R) to disease activities at low (L), moderate (M)…
  • Abstract Number: 1399 • 2019 ACR/ARP Annual Meeting

    Evaluation of Effectiveness and Usage Patterns of Tofacitinib in Treatment of Rheumatoid Arthritis in Australia: An Analysis from the OPAL-QUMI Real World Dataset

    Paul Bird1, Geoffrey Littlejohn 2, Belinda Butcher 3, Tegan Smith 4, Candida da Fonseca Pereira 5, David Witcombe 5 and Hedley Griffiths 6, 1Optimus Research, Kogarah, New South Wales, Australia, 2Monash Rheumatology, Clayton, Victoria, Australia, 3WriteSource Medical Pty Ltd, Lane Cove, New South Wales, Australia, 4OPAL Rheumatology Ltd, Sydney, New South Wales, Australia, 5Pfizer Australia, Sydney, New South Wales, Australia, 6Barwon Rheumatology Service, Geelong, Victoria, Australia

    Background/Purpose: Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis (RA). Limited data from large real-world patient populations exist to describe…
  • Abstract Number: 1436 • 2019 ACR/ARP Annual Meeting

    Analysis of Adverse Events of Methotrexate (MTX), bDMARDs and Tofacitinib (TOFA) Reported to Pharmaceuticals and Medical Devices Agency (PMDA), Japan

    Naonori Tsuda1, Shigeko Inokuma 2, Kenichi Hiraga 3, Yoshinori Masui 3 and Toshikazu Kano 3, 1Kohondai Hospital, National Center for Global health and Medicine, Ichikawa, Chiba, Japan, 2Chiba Central Medical Center, Ichikawa, Chiba, Japan, 3Kohnodai Hospital, National Center for Global health and Medicine, Ichikawa, Chiba, Japan

    Background/Purpose: Among DMARDs (disease modifying anti-rheumatic drugs), methotrexate (MTX), bDMARDs (biologic DMARDs) and JAK (Janus kinase) inhibitors are the major. Many adverse events of these…
  • Abstract Number: 1888 • 2019 ACR/ARP Annual Meeting

    Serum Calprotectin Is a Prognostic Marker for Drug-Free Remission in RA

    Emma de Moel1, Jürgen Rech 2, Michael Mahler 3, Johannes Roth 4, Anne Schouffoer 5, Karel Ronday 6, Thomas Huizinga 5, CF Allaart 7, René Toes 5, Georg Schett 8 and Diane van der Woude 1, 1Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Department of Internal Medicine 3, Friedrich-Alexander-University Erlangen-Nuremberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany, 3Inova Diagnostics, San Diego, CA, 4University of Muenster, Muenster, Germany, 5Leiden University Medical Center, Leiden, Netherlands, 6Haga Ziekenhuis, The Hague, Netherlands, 7Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands, Leiden, Netherlands, 8Department of Internal Medicine 3, Friedrich Alexander University Erlangen-Nuremberg, Erlangen, Germany

    Background/Purpose: The ability to accurately predict whether RA patients will flare following DMARD-tapering would open doors in clinical decision-making for achieving drug-free remission (DFR). Calprotectin…
  • Abstract Number: 2003 • 2019 ACR/ARP Annual Meeting

    Anti-Polygalacturonic Acid Antibody (PGA-Ab) Induced Bone Destruction in Rheumatoid Arthritis by Promoting Osteoclastogenesis via Integrin Beta 5

    JIAWEI XIE1 and HUI DAI 1, 1Peking University, Beijing, China (People's Republic)

    Background/Purpose: Anti-polygalacturonic acid antibody (PGA-Ab) is a new rheumatoid arthritis (RA)-related autoantibody first identified by our group. The sensitivity and specificity of PGA-Ab is even…
  • Abstract Number: 2159 • 2019 ACR/ARP Annual Meeting

    Pachymeningitis in Rheumatic Disease

    Rachel Kneeland1, John Berry 2, Sydney Brandwein 2 and Monika Starosta 2, 1Department of Internal Medicine, Advocate Lutheran General Hospital, Park Ridge, IL, 2Advocate Lutheran General Hospital, Park Ridge, IL

    Background/Purpose: Pachymeningitis is a rare complication of rheumatic disease. Patients present with hearing loss or other neurologic complications. Diagnosis is made by thickening of dura…
  • Abstract Number: 2300 • 2019 ACR/ARP Annual Meeting

    Risk Factors for Transfusion and Use of Tranexemic Acid in Patients with Rheumatoid Arthritis Undergoing Total Hip Arthroplasty and Total Knee Arthroplasty

    Kyle Morse 1, Jeremy Abolade 1, Nicole Heinz 1, Meng Zhang 2, Linda Russell 1, Serene Mirza 1, Dana Orange 3, Joshua Wright-Chisem 1, Mark Figgie 4, Peter Sculco 1 and Susan Goodman5, 1Hospital for Special Surgery, New York, 2The Feinstein Institute for Medical Research, Northwell Health, Manhasset, 3Rockefeller University, New York, 4Hospital for Special Surgery/Weill Cornell Medicine, New York, NY, New York, NY, 5Hospital For Special Surgery/Weill Cornell Medicine, New York, NY

    Background/Purpose: Utilization of total hip (THA) and total knee arthroplasty (THA) remains high for patients with RA, and most patients have moderate to high disease…
  • Abstract Number: 2322 • 2019 ACR/ARP Annual Meeting

    Toward Cardiovascular Risk Stratification in Rheumatoid Arthritis: Use of Regression Tree Analyses to Evaluate Impact of Serum Biomarkers and Cardiovascular Risk Factors on Carotid Intima Media Thickness

    Kimberly Liang1, Yaming Li 1, Suresh Mulukutla 1, Steven Reis 1, Marc Levesque 1, Donald Jones 1, Rachel Gartland 1, Jennifer Avolio 1, Ali Hakim Shoushtari 1, Flordeliza Villanueva 1, Larry Moreland 1 and Douglas Landsittel 2, 1University of Pittsburgh, Pittsburgh, PA, 2University of Pittsburgh, Pittsburgh, RI

    Background/Purpose: Both traditional cardiovascular (CV) risk factors and disease-related factors contribute to the increased risk of cardiovascular disease (CVD) in rheumatoid arthritis (RA). Mechanisms of…
  • Abstract Number: 2341 • 2019 ACR/ARP Annual Meeting

    Findings of Pulmonary Abnormalities on High Resolution Computed Tomography in a Cohort of Rheumatoid Arthritis Patients Without Known Lung Disease

    Scott Matson1, Kevin Deane 2, Christopher Collora 1, Xi Zheng 1, Marie Fester 1, Joyce Lee 1 and M. Kristen Demoruelle 3, 1University of Colorado, Denver, 2University of Colorado Denver, Division of Rheumatology, Aurora, CO, USA, Aurora, CO, 3University of Colorado Denver, Division of Rheumatology, Aurora, CO, USA, Aurora

    Background/Purpose: Pulmonary manifestations of rheumatoid arthritis (RA) lead to significant morbidity and mortality. Lung manifestations in RA are myriad, however little is known about how…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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