Abstracts tagged "rheumatoid arthritis (RA) and vaccines"

Abstract Number: 2092 • 2019 ACR/ARP Annual Meeting
Efficacy and Safety of the Adjuvanted Recombinant Zoster Vaccine in Adults with Pre-existing Potential Immune Mediated Diseases: A Pooled Post-hoc Analysis on Two Parallel Randomized Trials
Alemnew Dagnew¹, Debora Rausch ², Caroline Hervé ³, Toufik Zahaf ⁴ and Anne Schuind ¹, ¹GSK, Rockville, MD, ²GSK, Philadelphia, PA, ³GSK, Wavre, Belgium, ⁴GSK, Rixensart, Belgium
Background/Purpose: The increased risk of herpes zoster (HZ) in older adults is attributable to age-related decline in immunity. In 2 pivotal studies, ZOE-50 (NCT01165177) and…
Abstract Number: 231 • 2018 ACR/ARHP Annual Meeting
Rates of Influenza Vaccination in a Cohort of Patients with Rheumatoid Arthritis and Psoriatic Arthritis
Andreea Coca¹, James Dolan² and Christopher T. Ritchlin², ¹University of Rochester Medical Center, Rochester, NY, ²University of Rochester, Rochester, NY
Background/Purpose: The infections complicating rheumatic diseases cause significant morbidity and mortality. Rheumatoid arthritis and psoriatic arthritis patients are at increased risk of infection due to…
Abstract Number: 837 • 2018 ACR/ARHP Annual Meeting
Efficacy of High-Dose Versus Standard-Dose Influenza Vaccine in Seropositive Rheumatoid Arthritis Patients
Ines Colmegna¹, Mariana Useche², Katherine Rodriguez³, Marie Hudson⁴, Sasha Bernatsky⁵, Hacene Nedjar³, Elham Rahme⁶ and Brian Ward⁷, ¹The Research Institute of the McGill University Health Centre, Division of Rheumatology, Department of Medicine, McGill University, Montreal, Quebec, Canada, Montreal, QC, Canada, ²Medicine, The Research Institute of the McGill University Health Centre, Montreal, QC, Canada, ³The Research Institute of the McGill University Health Centre, Montreal, QC, Canada, ⁴Division of Rheumatology, Jewish General Hospital, Lady Davis Institute for Medical Research, Montreal, QC, Canada, ⁵Divisions of Rheumatology and Clinical Epidemiology, The Research Institute of the McGill University Health Centre, Montreal, QC, Canada, ⁶Epidemiology, The Research Institute of the McGill University Health Centre, Montreal, QC, Canada, ⁷Infectious Diseases, The Research Institute of the McGill University Health Centre, Montreal, QC, Canada
Background/Purpose: Rheumatoid arthritis (RA) patients have 2.75 fold increased risk of influenza and influenza-related illness than age-matched healthy controls. For this reason, RA patients are…
Abstract Number: 1223 • 2018 ACR/ARHP Annual Meeting
Reduced Antibody Titers Against Pertussis in Rheumatoid Arthritis
Caitlyn L. Holmes¹, Chloe Peyton², Amy Bier³, Tobias Donlon², Christie M. Bartels⁴ and Miriam A. Shelef^5,6, ¹University of Wisconsin - Madison, Madison, WI, ²University of Minnesota Medical School, Minneapolis, MN, ³Stritch School of Medicine of Loyola University Chicago, Chicago, IL, ⁴Rheumatology/Medicine, University of Wisconsin - Madison, Madison, WI, ⁵Department of Medicine, Division of Rheumatology, University of Wisconsin - Madison, Madison, WI, ⁶William S. Middleton Memorial Veterans Hospital, Madison, WI
Background/Purpose: Patients with rheumatoid arthritis, an autoimmune disease affecting ~1% of the population, have an increased risk of infection. Interestingly, data are mixed for response…
Abstract Number: 2427 • 2018 ACR/ARHP Annual Meeting
Adequate Vaccine Response According to the Italian Schedule Among the Offspring of Women Affected By Rheumatoid Arthritis and Treated throughout Pregnancy By Certolizumab Pegol: Case Series
Marianna Meroni¹, Maria De Santis², Elena Generali², Angela Ceribelli³, Marta Caprioli³, Giacomo Maria Guidelli², Natasa Isailovic², Gaetano Maria Fara⁴, Carlo Selmi² and Maurizio Cutolo⁵, ¹Rheumatology and Clinical Immunology, Humanitas Research Hospital, Rozzano, Italy, ²Rheumatology and Clinical Immunology Unit, Humanitas Research Hospital, Rozzano (MI), Italy, ³Rheumatology and Clinical Immunology, Humanitas Research Hospital, Rozzano (MI), Italy, ⁴Department of Public Health and Infectious Diseases, "Sapienza" University of Rome, Rome, Italy, ⁵Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, San Martino Polyclinic Hospital, Genoa, Italy, Genoa, Italy
Background/Purpose: Certolizumab pegol (CTZ) is a TNFα inhibitor indicated for the treatment of women affected by rheumatoid arthritis (RA) throughout the whole pregnancy. Some concern,…
Abstract Number: 827 • 2017 ACR/ARHP Annual Meeting
Temporary Methotrexate Discontinuation for 2 Weeks Improves Immunogenicity of Seasonal Influenza Vaccination in Patients with Rheumatoid Arthritis: A Randomized Clinical Trial
Jin Kyun Park¹, Kichul Shin², You-Jung Ha³, Yun Jong Lee⁴, Eun Young Lee⁵, Yeong Wook Song⁶, Yunhee Choi⁷, Kevin Winthrop⁸ and Eun Bong Lee⁹, ¹Division of Rheumatology, Seoul National University Hospital, Seoul, Korea, Republic of (South), ²Kyungnam villa #102, Division of Rheumatology, Department of Internal Medicine, SMG-SNU Boramae Medical Center, Seoul, Korea, Republic of (South), ³Yonsei University College of Medicine, Seoul, Korea, Republic of (South), ⁴Division of Rheumatology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea, Republic of (South), ⁵Division of Rheumatology, Department of Internal Medicine, Seoul National University, Seoul, Korea, Republic of (South), ⁶Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, and College of Medicine, Seoul National University, Seoul, Korea, The Republic of, Seoul, Korea, Republic of (South), ⁷Division of Medical Statistics, Medical Research Collaborating Center, Seoul National University College of Medicine, Seoul, Korea, Republic of (South), ⁸Oregon Health & Science University, Portland, OR, ⁹Division of Rheumatology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea, Republic of (South)
Background/Purpose: Methotrexate (MTX), a widely used immune-suppressive agent, decreases vaccine response in patients with rheumatoid arthritis (RA). We investigated whether a temporary MTX discontinuation for…
Abstract Number: 1824 • 2017 ACR/ARHP Annual Meeting
Evaluation of Pneumococcal and Tetanus Vaccine Responses in Patients with Rheumatoid Arthritis Receiving Baricitinib: Results from a Long-Term Extension Trial Substudy
Kevin Winthrop¹, Clifton O. Bingham III², John D. Bradley³, Maher Issa³, Rena Klar⁴ and Cynthia E. Kartman³, ¹Oregon Health and Sciences University, Portland, OR, ²Rheumatology, Johns Hopkins University, Baltimore, MD, ³Eli Lilly and Company, Indianapolis, IN, ⁴Quintiles IMS Holdings, Inc., Durham, NC
Background/Purpose: Clinical guidelines recommend pneumococcal and tetanus vaccinations in patients (pts) with RA.1 Baricitinib (bari) is an oral, selective Janus kinase (JAK) 1/JAK 2 inhibitor…
Abstract Number: 2029 • 2017 ACR/ARHP Annual Meeting
Improved Provider Awareness and Delivery of Zoster Vaccination in Patients with Rheumatoid Arthritis Contemplating Biologic Therapy: Need to Target Eligible Patients Prescribed for Vaccination Post-Clinic
Gina Prakash¹, Kenneth O'Rourke² and Stephen Mullis³, ¹Department of Internal medicine, Section on Rheumatology and Immunology, Wake Forest School of Medicine, Winston Salem, NC, ²Department of Internal Medicine, Section on Rheumatology and Immunology, Wake Forest School of Medicine, Winston-Salem, NC, ³Department of Internal Medicine, Section on Rheumatology and Immunology, Wake Forest School of Medicine, Winston Salem, NC
Background/Purpose: Vaccination against herpes zoster (shingles) can reduce the frequency of infection, the severity of shingles should it occur, and the frequency of post-herpetic neuralgia.…
Abstract Number: 2396 • 2017 ACR/ARHP Annual Meeting
Safety and Humoral and Cell-Mediated Immune Responses to Herpes Zoster Vaccine in Patients with Rheumatoid Arthritis
JungHee Koh¹, Ji-Won Kim², Seung-Ki Kwok³, Ji Hyeon Ju⁴ and Sung-Hwan Park⁵, ¹Seochogu, Banpodaero, 222, Division of Rheumatology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of (South), ²Medicine, Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of (South), ³[email protected], Division of Rheumatology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of (South), ⁴Division of Rheumatology, Department of Internal Medicine,, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of (South), ⁵Kangnam St Mary's Hosp, Seoul, Korea, Republic of (South)
Background/Purpose: To examine humoral and cellular immune responses induced by a live attenuated herpes zoster (HZ) vaccine in patients with rheumatoid arthritis (RA) compared with…
Abstract Number: 2414 • 2017 ACR/ARHP Annual Meeting
Knowledge and Adherence to Current Immunization Recommendations in Patients with Rheumatoid Arthritis in Mexico
Andrea Sofia Cepeda-Perez¹, Nina Tello Winniczuk² and Alejandro Diaz-Borjon², ¹Internal Medicine, Hospital Angeles Lomas, Huixquilucan, Estado de Mexico, Mexico, ²Internal Medicine and Rheumatology, Hospital Angeles Lomas, Huixquilucan, Estado de Mexico, Mexico
Background/Purpose: Patients with RA have a two to four-fold increased risk of developing infections than the general population. This is due to both, the disease…
Abstract Number: 2415 • 2017 ACR/ARHP Annual Meeting
Immunogenicity and Persistence of a Prime-Boost Re-Vaccination Strategy for Pneumococcal Vaccines (13-Valent Pneumococcal Conjugate Vaccine + 23-Valent Pneumococcal Polysaccharide Vaccine) in Patients with Rheumatoid Arthritis: A Pilot Study
Mathilde Bahuaud¹, Constance BEAUDOUIN², Anna Molto³, Odile Launay⁴, Frederic Batteux⁵ and Maxime Dougados⁶, ¹Université Paris Descartes, Sorbonne Paris Cité AP-HP, Département d’Immunologie Biologique, Groupe Hospitalier Cochin Broca Hôtel-Dieu, Paris, France, Paris, France, ²Cochin Hospital, APHP, Rheumatology B, Paris, France, ³Hôpital Cochin, Department of Rheumatology, Paris Descartes University, Paris, France, ⁴Université Paris Descartes, Sorbonne Paris Cité AP-HP, Groupe Hospitalier Cochin Broca Hôtel-Dieu, Fédération d'Infectiologie, Paris, France; Inserm, F-CRIN I-REIVAC., Paris, France, ⁵Immunology, APHP Hopital Cochin, Paris, France, ⁶Department of Rheumatology, Paris Descartes University, Hôpital Cochin, Paris, France
Background/Purpose: Patients with rheumatoid arthritis (RA) are at an increased risk of some serious vaccine-preventable infections, like Pneumococcal infections. Since 2013, French vaccine recommendations committee…
Abstract Number: 424 • 2016 ACR/ARHP Annual Meeting
Adherence to American College of Rheumatology Immunization Recommendations for Rheumatoid Arthritis Patients in a Tertiary Care Health System and Opportunities to Close the Gap
Maryann Kimoto¹, Mary Chester M. Wasko² and Tarun S. Sharma³, ¹Internal Medicine, Internal Medicine Residency Program, Allegheny Health Network, Pittsburgh, PA, ²Lupus Center, Pittsburgh, PA, ³Rheumatology, Lupus Center of Excellence, Allegheny Health Network, Pittsburgh, PA
Background/Purpose: A total of 85 adult RA patients were identified. The mean age was 61.5 yrs, 84.7% were female, 85.9% were Caucasian, and the mean…
Abstract Number: 427 • 2016 ACR/ARHP Annual Meeting
Identifying Barriers to Zoster Vaccination Rates Among RA Patients in an Academic Rheumatology Practice
Ami Joglekar¹, Ashley Blaske² and Narender Annapureddy³, ¹Department of Medicine, Division of Rheumatology, Vanderbilt University, Nashville, TN, ²Internal Medicine/Pediatrics, Vanderbilt University, Nashville, TN, ³Vanderbilt University, Nashville, TN
Background/Purpose: The risk of herpes zoster (HZ) infection in patients with rheumatic disease is 1.5 to 2 times that of the general population. The 2012 ACR Treatment…
Abstract Number: 1502 • 2016 ACR/ARHP Annual Meeting
Vaccination Program to Prevent Hospital Admissions Due to Serious Respiratory Infections in Rheumatoid Arthritis Patients. Prosprective Study of 294 Patients
Lucia C. Domínguez-Casas¹, Paz Rodríguez-Cundín², Vanesa Calvo-Río¹, Ricardo Blanco¹, Nuria Vegas-Revenga³, Carlos Fernández Díaz¹, Virginia Portilla³, FM Antolin², MH Rebollo-Rodrigo², Alfonso Corrales¹, Natalia Palmou-Fontana¹ and Miguel Angel Gonzalez-Gay¹, ¹Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Santander, Spain, ²Preventive Medicine, Hospital Universitario Marqués de Valdecilla. IDIVAL, Santander, Spain, ³Hospital Universitario Marqués de Valdecilla. IDIVAL, Santander, Spain
Background/Purpose: Patients with Rheumatoid Arthritis (RA) are at increased risk of infections, especially serious respiratory infections. Immunization is a recommended to reduce these complications.…
Abstract Number: 1503 • 2016 ACR/ARHP Annual Meeting
Patterns and Factors Associated with Immunization Among Adult Patients with Rheumatic Diseases in the US
Huifeng Yun¹, Shuo Yang², Sofia Pedro³, Jeffrey Curtis⁴ and Kaleb Michaud⁵, ¹Epidemiology, University of Alabama at Birmingham School of Public Health, Birmingham, AL, ²Division of Clinical Immunology & Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ³National Data Bank for Rheumatic Diseases, Wichita, KS, ⁴Division Clinical Immunology & Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ⁵University of Nebraska Medical Center, Omaha, NE
Background/Purpose: Rates of adult vaccination are low in patients with autoimmune disease despite broad recommendations for many years. In the U.S., pneumococcal vaccination is recommended…

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