ACR Meeting Abstracts

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Abstracts tagged "rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE)"

  • Abstract Number: 321 • 2019 ACR/ARP Annual Meeting

    Adherence to Weight-Based Dosing Guidelines in Patients Receiving Hydroxychloroquine for Rheumatoid Arthritis and Systemic Lupus Erythematosus

    Tara Skorupa1 and Robert Shmerling 1, 1Beth Israel Deaconess Medical Center / Harvard Medical School, Boston, MA

    Background/Purpose: Hydroxychloroquine (HCQ) is a commonly prescribed medication for systemic lupus erythematosus (SLE), rheumatoid arthritis (RA) and other rheumatic diseases. However, HCQ may cause retinal…
  • Abstract Number: 2409 • 2019 ACR/ARP Annual Meeting

    24-hour Activity Profiling in People Living with Arthritis: Habits Matter

    Lynne Feehan1, Linda Li 1, Na Lu 2 and Hui Xie 3, 1Arthritis Research Canada and University of British Columbia, Vancouver, Canada, Vancouver, BC, Canada, 2Arthritis Research Canada, Vancouver, Canada, Vancouver, BC, Canada, 3Arthritis Research Canada and Simon Fraser University, Vancouver, BC, Canada

    Background/Purpose: Current practices promoting change in physical activity classify individuals as being more or less active. However, across 24-hours people spend time in different types…
  • Abstract Number: 106 • 2018 ACR/ARHP Annual Meeting

    Highly Elevated Levels of Anti-Mitochondrial Antibodies in Systemic Lupus Erythematosus and Rheumatoid Arthritis

    Richard Moore1 and Christian Lood2, 1Division of Rheumatology, University of Washington, Seattle, WA, 2Department of Medicine, Division of Rheumatology, University of Washington, Seattle, WA

    Background/Purpose: We recently described the phenomenon in systemic lupus erythematosus (SLE) in which mitochondria are extruded into the extracellular space during formation of neutrophil extracellular…
  • Abstract Number: 737 • 2018 ACR/ARHP Annual Meeting

    Atherogenic Index of Plasma in Women with Systemic Lupus Erythematosus and Rheumatoid Arthritis: A 10-Year Potential Predictor of Cardiovascular Disease

    Nevin Hammam1,2 and Tamer A Gheita3, 1University of Alberta, Edmonton, AB, Canada, 2Rheumatology and Rehabilitation Department, Assiut University, Assiut, Egypt, 3Rheumatology Department Faculty of Medicine, Cairo University, Cairo, Egypt

    Background/Purpose: Patients with systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) are characterized by an increased frequency of cardiovascular diseases (CVD). Early diagnosis of these…
  • Abstract Number: 1860 • 2018 ACR/ARHP Annual Meeting

    Development and Validation of a Microrna Panel to Differentiate between Patients with Rheumatoid Arthritis, Systemic Lupus Erythematosus, and Control Subjects

    Michelle J. Ormseth, Joseph F. Solus, Quanhu Sheng, Fei Ye, Qiong Wu, Yan Guo, Annette M. Oeser, Ryan Allen, Kasey Vickers and C Michael Stein, Vanderbilt University Medical Center, Nashville, TN

    Background/Purpose: MicroRNAs (miRNAs) are short non-coding RNAs that regulate genes and have utility as disease biomarkers. Use of small RNA (sRNA) sequencing along with unbiased…
  • Abstract Number: 2179 • 2018 ACR/ARHP Annual Meeting

    Poor Rates of Screening for Retinal Toxicity in Patients on Antimalarial Medications: A Population-Based Study

    Ksenia Gukova1, John M. Esdaile2, Hamid Tavakoli3 and J. Antonio Avina-Zubieta1,2, 1Division of Rheumatology, Department of Medicine, University of British Columbia, Vancouver, BC, Canada, 2Arthritis Research Canada, Richmond, BC, Canada, 3Arthritis Research Canada, Vancouver, BC, Canada

    Background/Purpose: Antimalarial drugs (AM) are commonly used to treat rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). AM can be associated with retinal toxicity that…
  • Abstract Number: 8L • 2017 ACR/ARHP Annual Meeting

    Prevalence of Blindness in a Cohort of Rheumatologic Patients Treated with Hydroxychloroquine

    Dilpreet Singh1, Leila Muhieddine2, Douglas Einstadter3 and Stanley Ballou4, 1Rheumatology, Case Western Reserve University School of Medicine at MetroHealth Medical Center, Cleveland, OH, 2Internal Medicine, Case Western Reserve University, MetroHealth Medical Center, Cleveland, OH, 3Case Western Reserve University at MetroHealth Medical Center, Cleveland, OH, 4Rheumatology, Case Western Reserve University/MetroHealth Medical Center, Cleveland, OH

    Background/Purpose: Hydroxychloroquine (HCQ) is widely used in the treatment of chronic rheumatic diseases. Its long-standing use has been associated with retinopathy in a daily and…
  • Abstract Number: 1027 • 2017 ACR/ARHP Annual Meeting

    Quantification of Leukocytes’ Secretome to Guide Diagnosis and Treatment Options in Patients with Suspected Chronic Auto-Inflammatory Syndromes

    Philippe A. Tessier1, Marie-Pier Longchamps1, Nathalie Amiable1, Nathalie Pagé1, Laetitia Michou2, Louis Bessette2, Paul R. Fortin1, Alexandra Albert2, Anne-Laure Chetaille2 and Martin Pelletier1, 1Infectious Diseases and Immunity Research Division, CHU de Québec-Université Laval Research Center, Québec, QC, Canada, 2Division of Rheumatology, Department of Medicine, CHU de Québec-Université Laval, Québec, QC, Canada

    Background/Purpose:  Auto-inflammatory syndromes are inherited conditions characterized by recurrent inflammation (fever, abdominal pain, dermatitis, arthritis). Diagnosis and treatments are challenging as detection rate of mutations…
  • Abstract Number: 1083 • 2017 ACR/ARHP Annual Meeting

    Rheumatoid Arthritis Patients Achieved Better Quality of Life Than Systemic Lupus Erythematosus Patients at Sustained Remission: The Impact of Disease Diagnosis on Health-Related Quality of Life Outcomes

    Virginia Pascual-Ramos1, Irazú Contreras-Yáñez2, Katya Valencia-Quiñones3 and Juanita Romero-Diaz4, 1Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, 2Inmunología y Reumatología, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, 3Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, 4Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico city, Mexico

    Background/Purpose: Patients with Systemic Lupus Erythematous (SLE) and Rheumatoid Arthritis (RA) had profound negative effects on their health-related quality of life (HRQoL) that can be…
  • Abstract Number: 1086 • 2017 ACR/ARHP Annual Meeting

    Screening and Intervention of Depression in Rheumatoid Arthritis and Systemic Lupus Erythematosus

    Rui Zhang1, Priya Prakash2, Amy Wasserman3, Kirk Sperber4 and Julia Ash5, 1Medicine -Rheumatology, New York Medical College / Westchester Medical Center, valhalla, NY, 2Rheumatology, NYMC /WMC, VALHALLA, NY, 3Medicine - Rheumatology, New York Medical College / Westchester Medical Center, VALHALLA, NY, 4New York Medical College / Westchester Medical Center, Valhalla, NY, 5Medicine -Rheumatology, New York Medical College / Westchester Medical Center, Valhalla, NY

    Background/Purpose: Depression is common and associated with worse outcomes among patients with RA and SLE. Our study assessed depression using Patient Help Questionnaire (PHQ-9) and…
  • Abstract Number: 1261 • 2017 ACR/ARHP Annual Meeting

    The Effects of Disease Burden, Helplessness, and Pain on Depressive Symptoms in Rheumatoid Arthritis and Systemic Lupus Erythematosus

    Sera Ramadan1, Perry M. Nicassio2, George Karpouzas3 and Sarah Ormseth4, 1Internal Medicine, Dignity Health St. Mary Medical Center, Long Beach, CA, 2Cousins Center for PNI, UCLA, LA, CA, 3Division of Rheumatology, Harbor-UCLA Medical Center, Torrance, CA, 4Rheumatology, Harbor-UCLA Medical Center, Torrance, CA

    Background/Purpose: This research tested an integrated framework examining patient global assessment of disease activity (PtGA), maladaptive illness beliefs and pain as determinants of mood disturbance…
  • Abstract Number: 1299 • 2017 ACR/ARHP Annual Meeting

    Patient-Reported Disease Activity and Adverse Pregnancy Outcomes in Systemic Lupus Erythematosus and Rheumatoid Arthritis

    Nathaniel Harris1, Amanda M. Eudy2 and Megan E. B. Clowse2, 1Duke University School of Medicine, Durham, NC, 2Division of Rheumatology, Department of Medicine, Duke University Medical Center, Durham, NC

    Background/Purpose: Patient-reported measures of disease activity may provide useful adjuncts to physician-reported measures in identifying pregnancies at greater risk for adverse pregnancy outcomes. Little is…
  • Abstract Number: 2565 • 2017 ACR/ARHP Annual Meeting

    Pharmacodynamic Modeling of BTK Occupancy Versus Efficacy in Ra and SLE Models Using the Novel Specific BTK Inhibitor Evobrutinib

    Philipp Haselmayer1, Monsterrat Camps2, Lesley Liu-Bujalski3, Federica Morandi4, Jared Head4, Simone C. Zimmerli5, Lisa Bruns6, Andrew Bender7, Patricia Schroeder8 and Roland Grenningloh9, 1CBD, Merck KGaA, Darmstadt, Germany, 2Immunology, Merck Serono S.A., Geneva, Switzerland, 3Medicinal Chemistry, EMD Serono Research & Development Institute, Inc. (a business of Merck KGaA, Darmstadt, Germany), Billerica, MA, 4Biomolecular Pharmacology, EMD Serono Research & Development Institute, Inc. (a business of Merck KGaA, Darmstadt, Germany), Billerica, MA, 5Immunology, EMD Serono Research & Development Institute, Inc. (a business of Merck KGaA, Darmstadt, Germany), Billerica, MA, 6Immunology, Merck KGaA, Darmstadt, Germany, 7TIP Immunology, EMD Serono Research and Development Institute, Billerica, MA, 8Translational Pharmacology, EMD Serono Research & Development Institute, Inc. (a business of Merck KGaA, Darmstadt, Germany), Billerica, MA, 9EMD Serono Research & Development Institute, Inc. (a business of Merck KGaA, Darmstadt, Germany), Billerica, MA

    Background/Purpose: Bruton’s tyrosine kinase (BTK) is a clinically-proven target in several hematological indications. Due to its role in mediating the signaling of both B cell…
  • Abstract Number: 2825 • 2017 ACR/ARHP Annual Meeting

    A Possible Environmental Origin for a Proportion of the Genetic Risk of Rheumatoid Arthritis and Systemic Lupus Erythematosus

    John B. Harley1, Xiaoting Chen1, Mario Pujato2, Daniel Miller1, Avery Maddox1, Carmy Forney3, Albert Magnusen3, Arthur Lynch1, Kashish Chetal4, Masashi Yukawa5, Artem Barski6, Nathan Salomonis4, Kenneth Kaufman7, Leah C. Kottyan8 and Matthew Weirauch9, 1Center for Autoimmune Genomics and Etiology (CAGE), Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2Center of Autoimmune Genomics and Etiology (CAGE), Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 3Center of Autoimmune Genomics and Etiology (CAGE), Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 4Division of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 5Divisions of Allergy and Immunology and Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 6Divisions of Allergy and Immunology and Bioinformatics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 7Center for Autoimmune Genomics and Etiology (CAGE), Cincinnati Children's Hospital Medical Center; US Department of Veterans Affairs Medical Center, Cincinnati, OH, 8Center for Autoimmune Genomics and Etiology (CAGE), Division of Allergy and Immunology, Cincinnati Children's Hospital, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 9Center for Autoimmune Genomics and Etiology (CAGE) and Divisions of Biomedical Informatics and Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH

    Background/Purpose: Nearly 150 genetic loci are convincingly associated with lupus (SLE) or rheumatoid arthritis (RA) and underlie their incompletely understood mechanisms of pathogenesis. Since 90%…
  • Abstract Number: 2437 • 2016 ACR/ARHP Annual Meeting

    Causes of Cesarean Section and Labor Induction in Systemic Lupus Erythematosus and Rheumatoid Arthritis Pregnancies

    Amanda M. Eudy, Laura Neil and Megan E. B. Clowse, Rheumatology, Duke University Medical Center, Durham, NC

    Background/Purpose: Women with SLE and RA have an increased risk of delivering a preterm infant. However, the causes of these preterm births remain unknown. Some…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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