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Abstracts tagged "rheumatoid arthritis (RA) and spondylarthritis"

  • Abstract Number: 2117 • 2019 ACR/ARP Annual Meeting

    Impact of Tapering Targeted Therapies (bDMARDs or Jakinibs) on the Risk of Adverse Events of Special Interest in Patients with Rheumatoid Arthritis or Spondyloarthritis: A Systematic Analysis of the Literature and Meta-analysis

    DOROTHEE VINSON1, LUC MOLLET-BENHAMOU 2, Yannick Degboe 3, Thao Pham 4, Thomas BARNETCHE 5, Arnaud Constantin 6 and Adeline Ruyssen-Witrand 7, 1AP-HM CHU Marseille, Marseille, France, 2CHU Toulouse, Toulouse, France, 3University of Glasgow, Glasgow, United Kingdom, 4Aix-Marseille University, CHU Marseille, department of Rheumatology, 13,000 Marseille, France, Marseille, France, 5CHU Bordeaux, Toulouse, France, 6CHU TOUOUSE, TOULOUSE, France, 7Rheumatology Unit, Toulouse university Hospital, UMR 1027, Inserm, Université Paul Sabatier Toulouse III, Toulouse, France

    Background/Purpose: A previous meta-analysis1 showed that tapering of bDMARDs does not increase the risk of relapse in rheumatoid arthritis (RA) patients with remission or low…
  • Abstract Number: 517 • 2018 ACR/ARHP Annual Meeting

    Effects of Statin-Treatment on Coronary Plaques in Patients with Inflammatory Joint Diseases

    Silvia Rollefstad1, Mona Svanteson2, Nils Einar Kløw2,3, Jonny Hisdal4, Eirik Ikdahl5, Joseph Sexton6, Ylva Haig2 and Anne Grete Semb1, 1Preventive Cardio-Rheuma clinic, Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 2Division of Radiology and Nuclear Medicine, Oslo University Hospital, Ullevål, Oslo, Norway, 3Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway, 4Department of Vascular investigations, Oslo University Hospital, Aker, Oslo, Norway, 5Preventive Cardio-Rheuma clinic, Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 6Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway

    Effects of Statin-treatment on Coronary Plaques in Patients with Inflammatory Joint DiseasesBackground/Purpose: Statins have an established preventive effect on coronary artery disease in the general…
  • Abstract Number: 698 • 2018 ACR/ARHP Annual Meeting

    Discontinuation of Methotrexate or TNF Inhibitors in Patients with Rheumatoid Arthritis, Psoriatic Arthritis, and Ankylosing Spondylitis

    Michael D. George1, Joshua Baker2 and Alexis Ogdie3, 1Division of Rheumatology, University of Pennsylvania, Philadelphia, PA, 2Philadelphia VA Medical Center and University of Pennsylvania, Philadelphia, PA, 3Medicine/Rheumatology and Epidemiology, University of Pennsylvania, Philadelphia, PA

    Background/Purpose: Methotrexate and TNF inhibitors (TNFi) are commonly used in the treatment of RA, PsA, and other SpA. While MTX is a mainstay of RA…
  • Abstract Number: 2502 • 2018 ACR/ARHP Annual Meeting

    Influence of the Treatment with Biologic Agents in the Viremia By the Endogenous Anelovirus Torque Teno Virus in Patients with Chronic Arthritis

    Maria Martin-Lopez1, Eliseo Albert2, Esther Rodriguez-Almaraz3, Isidoro Gonzalez-Alvaro4, Mario Fernandez-Ruiz5, Jose M. Aguado5, David Navarro2 and Jose L. Pablos6, 1Rheumatology Department, Instituto de Investigación Hospital 12 de Octubre, Madrid, Spain, 2Microbiology, Instituto de Investigación INCLIVA, Hospital Clínico, Valencia, Spain, 3Hospital Universitario 12 de Octubre, Madrid, Spain, 4Rheumatology Department, Hospital Universitario de La Princesa, IIS-IP, Madrid, Spain, 5Instituto de Investigación Hospital 12 de Octubre. Unit of Infectious Diseases, Madrid, Spain, 6Rheumatology, Rheumatology Department, Hospital Universitario 12 de Octubre, Spain, Madrid, Spain

    Background/Purpose: Torque teno virus (TTV) is an endogenous anellovirus that is highly prevalent in adult healthy subjects (up to 90%) without known pathogenicity. Increased replication…
  • Abstract Number: 463 • 2017 ACR/ARHP Annual Meeting

    Certolizumab Pegol for Fatigue in Chronic Inflammatory Rheumatic Diseases: A Meta-Analysis

    Yesim Ozguler1, Sinem Nihal Esatoglu1, Guzin Karatemiz1, Ali Ugur Unal2, Gul Guzelant1, Elif Dincses3, Mustafa Erdogan1, Sema Kaymaz Tahra2 and Gulen Hatemi1, 1Istanbul University, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey, 2Departement of Internal Medicine, Division of Rheumatology, Marmara University, Istanbul, Turkey, 3Istanbul University, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, İstanbul, Turkey

     Background/Purpose: Fatigue is an important problem that impairs life quality in patients with rheumatic diseases. Although fatigue is often associated with disease activity, only a…
  • Abstract Number: 2800 • 2017 ACR/ARHP Annual Meeting

    Long-Term Safety and Efficacy of Biosimilar Infliximab (CT-P13) after Switching from Originator Infliximab: Results from the 26-Week Open Label Extension of a Randomized Norwegian Trial

    Guro Løvik Goll1, Kristin Kaasen Jørgensen2, Joe Sexton1, Inge C Olsen3, Nils Bolstad4, Merete Lorentzen5, Espen A. Haavardsholm6, Cato Mork7, Jorgen Jahnsen8 and Tore K Kvien9, 1Dept Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 2Dept Gastroenterology, Akershus University Hospital, Lørenskog, Norway, 3Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 4Department of Medical Biochemistry,, OUS-Radiumhospitalet, Oslo, Norway, 5Dept of Dermatology, Rikshospitalet, Oslo, Norway, 6Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 7Dept of cancer and Molecular medicine, Norwegian University of Science and Technology, Trondheim, Norway, 8Dept of Gastroenterology, Akershus University Hospital, Lorenskog, Norway, 9Diakonhjemmet Hospital, Oslo, Norway

    Background/Purpose: TNF-inhibitors (TNFi) have improved treatment of rheumatoid arthritis (RA), spondyloarthritis (SpA), psoriatic arthritis (PsA) , Crohn’s disease (CD), ulcerative colitis (UC), and chronic plaque…
  • Abstract Number: 1169 • 2016 ACR/ARHP Annual Meeting

    A Systematic Review of Rheumatic Disease Epidemiology in the Indigenous Populations of Canada, the United States, Australia and New Zealand

    Cairistin McDougall1, Kelle Hurd1 and Cheryl Barnabe2, 1University of Calgary, Calgary, AB, Canada, 2Division of Rheumatology, University of Calgary, Calgary, AB, Canada

    Background/Purpose: Two important reviews have summarized the epidemiology of rheumatic disease (Peschken 1999) and RA (Ferucci 2005) in Indigenous populations of North America. Our objective…
  • Abstract Number: 2169 • 2016 ACR/ARHP Annual Meeting

    Presence of Cardiovascular Risk Factors Across Different Inflammatory Joint Disease Entities: Results from a Norwegian, Multi-Centre Project

    Grunde Wibetoe1, Eirik Ikdahl2, Silvia Rollefstad2, Anne Salberg3, Dag Magnar Soldal4, Tore K Kvien5, Glenn Haugeberg6 and Anne Grete Semb7, 1Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 2Diakonhjemmet Hospital, Oslo, Norway, 3Hospital for Rheumatic Diseases, Lillehammer, Norway, 4Rheumatology, Hospital of Southern Norway, Kristiansand, Norway, 5Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 6Martina Hansens Hospital, Bærum, Norway, 7Preventive Cardio-Rheuma clinic, Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway

    Background/Purpose: EULAR recommendations for cardiovascular disease (CVD) risk management in inflammatory joint diseases (IJD) advocates annual CVD risk assessments to reduce the increased CVD risk.…
  • Abstract Number: 2930 • 2016 ACR/ARHP Annual Meeting

    Specific Metabolic and Functional Changes in Peripheral CD8+ T Cells Specifically Distinguish RA from PSA and SPA

    Rui Carvalho1, Christine Tucher2, Lars Tykocinski2, Susanne Neu2, Karel Klika3, H.-M. Lorenz2 and Margarida Souto-Carneiro2, 1Life Sciences Department, FCTUC, Center for Functional Ecology, University of Coimbra, Coimbra, Portugal, 2Rheumatology, Department of Rheumatology, University of Heidelberg, Heidelberg, Germany, 3German Cancer Research Center, Heidelberg, Germany

    Background/Purpose:  Studies by our team and others have shown that CD8 T cells (CD8s) in RA have a pro-inflammatory, cytotoxic effector phenotype and may, therefore,…
  • Abstract Number: 1537 • 2015 ACR/ARHP Annual Meeting

    Effect of TNF-Alpha Blockade on Body Composition in Inflammatory Rheumatic Disease: Systematic Review with Meta-Analysis

    sarah marouen1, Thomas Barnetche2, Bernard Combe3, Jacques Morel4 and Claire I. Daien4, 1Rhumatology Department, Lapeyronie Hospital and Montpellier University, Montpellier, France, 2Rheumatology Department, Pellegrin University Hospital, BORDEAUX, France, 3Rheumatology, Hopital Lapeyronie, Montpellier, France, 4Department of rheumatology, Lapeyronie Hospital and Montpellier University, Montpellier, France

    Background/Purpose: Patients with chronic inflammatory rheumatic disease have elevated circulating concentrations of TNF-alpha and other pro-inflammatory cytokines that can modify body composition. Metabolic changes are…
  • Abstract Number: 2824 • 2015 ACR/ARHP Annual Meeting

    Autoantibodies Against CD74 – a New Diagnostic Marker for Spondyloarthritis (SpA)

    Bruno Larida, AESKU.DIAGNOSTICS INC, Oakland, CA

    Background/Purpose: Spondyloarthritis (SpA) is a common debilitating inflammatory disorder. The pathogenesis of axial spondyloarthritis (axSpA) including ankylosing spondylitis (AS), although known to be strongly associated…
  • Abstract Number: 2874 • 2015 ACR/ARHP Annual Meeting

    Two-Years Survival of Golimumab in Patients with Rheumatoid Arthritis, Psoriatic Arthritis, and Axial Spondyloarthritis and Predictors Thereof in Real-Life Settings

    Leonardo Santo1, Angelo Semeraro2, Carmelo Zuccaro3, Maria Grazia Anelli4, Romano Bucci5, Antonio Marsico6, Laura Quarta7, Giorgio Carlino8, Francesco Paolo Cantatore9, Annamaria Gaudio10, Fabio Cacciapaglia11, Oriana Casilli12, Paola Chiara Francesca Falappone13 and Florenzo Iannone14, 1DSS4 Barletta, ASL BT Andria - Rheumatology Service, Barletta, Italy, 2Unità Operativa di Reumatologia ASL Taranto, Taranto, Italy, 3U.O.of Geriatrics, Outpatient clinic of Rheumatology, Brindisi, Italy, 4DIM, Rheumatology Unit, Bari, Italy, 5A.O.U., Rheumatology Hospital Unit, Foggia, Italy, 6Outpatient clinic of Rheumatology, Taranto,, Italy, 7Department of Rheumatology, "V.Fazzi" Hospital, San Cesario di Lecce, Italy, 8ASL LE - DSS Casarano and Gallipoli, Rheumatology Service, Gallipoli, Italy, 9Department of Rheumatology, University of Foggia,, Foggia, Italy, 10Department of Rheumatology, University of Foggia, Foggia, Italy, 11Internal Medicine Unit and Outpatient clinic of Rheumatology, “N. Melli” Hospital, San Pietro Vernotico (BR), Italy, 12Department of Rheumatology, "Vito Fazzi" Hospital, San Cesario di Lecce, Italy, 13Internal Medicine Unit - Outpatient clinic of Rheumatology,, "S. Camillo de' Lellis" Hospital, Mesagne (BR), Italy, 14Interdisciplinary Department of Medicine (DIM), Rheumatology Unit, University of Bari, Bari, Italy

    Background/Purpose: It has previously been shown that the survival of anti-TNF drugs was lower in Rheumatoid arthritis (RA) than in other chronic arthritis1. The objective…
  • Abstract Number: 675 • 2015 ACR/ARHP Annual Meeting

    Vitamin D Deficiency in Rheumatoid Arthritis, Ankylosing Spondylitis and Psoriatic Arthritis. Results of the CARMA Study

    Ana Urruticoechea1, Maria Auxiliadora Martin2, Santos Castañeda3, Carlos Alberto Sánchez-Piedra2, Carlos González-Juanatey4, Javier Llorca5, Federico Díaz-González6 and Miguel Angel Gonzalez-Gay7, 1Hospital Can Misses, Ibiza, Spain, 2Research Unit of Spanish Society of Rheumatology,, Madrid, Spain, 3Rheumatology, H.U. La Princesa, Madrid, Spain, 4Division or Cardiology, Hospital Lusus Augusti, Lugo, Spain, 5Department of Epidemiology and Computational Biology, School of Medicine, University of Cantabria, and CIBER Epidemiología y Salud Pública (CIBERESP), IDIVAL, Santander, Spain, 6Investigation Unit, Sociedad Española de Reumatológía, Madrid, Spain, 7Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Santander, Spain

    Background/Purpose: To study the association between 25-hydroxyvitamin D (25(OH)D) levels and the clinical characteristics of patients with chronic inflammatory rheumatic diseases (CIRD). Methods: Cross section…
  • Abstract Number: 2208 • 2014 ACR/ARHP Annual Meeting

    Ovarian Reserve Alterations in Premenopausal Women with Rheumatoid Arthritis, Behcet’s Disease and Spondyloarthritis – Impact on Anti-Muellerian Hormone Levels

    Joerg C. Henes1, Julia Froeschlin2, Andre Taran3, Theodoros Xenitidis4 and Melanie Henes5, 1Department of Internal Medicine II, Rheumatology Division, University Hospital Tuebingen, Tuebingen, Germany, 2University Tuebingen, Tuebingen, Germany, 3University Hospital for Women Tuebingen, Tuebingen, Germany, 4Internal Medincine II, devision for Rheumatology, University Hospital Tuebingen, Tuebingen, Germany, 5University Hospital for Women, Tuebingen, Germany

    Background/Purpose: Recent publications showed a negative influence of systemic lupus erythematosus and antiphospholipid antibody syndrome on female ovarian reserve (OR). Other authors did not find…
  • Abstract Number: 1596 • 2014 ACR/ARHP Annual Meeting

    Clinical Characteristics and Outcome of Golimumab Treatment Differs Between Bio-naïve and Patients Previously Exposed to Biologicals. Nationwide Results on Rheumatoid Arthritis (RA), Psoriatic Arthritis (PsA), Ankylosing Spondylitis (AS) and Other Spondylarthritidies (SpA)

    Saedis Saevarsdottir1, Michele Santacatterina2, Carl Turesson3, Helena Forsblad4, Lennart Jacobsson4 and Staffan Lindblad5, 1Rheumatology Unit, Department of Medicine, Karolinska institutet and Karolinska University Hospital, Stockholm, Sweden, 2Biostatistics Core Facility, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, 3Section of Rheumatology, Department of Clinical Sciences, Malmö, Lund University, Malmö, Sweden, 4Dept of Rheumatology & Inflammation Research, Institute of Medicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden, 5Department of Learning, Informatics, Management and Ethics, Karolinska Institutet, Stockholm, Sweden

    Background/Purpose Golimumab is a TNF inhibiting biological drug that was approved in Sweden in 2010 for the treatment of RA, PsA and AS. Our previous…
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