ACR Meeting Abstracts

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Abstracts tagged "registry"

  • Abstract Number: 0794 • ACR Convergence 2021

    Application of Treat to Target and Impact of Sustained Low Disease Activity or Remission on Function in Rheumatoid Arthritis Patients

    Louis Bessette1, Edward Keystone2, Proton Rahman3, Keltie Anderson4, Emmanouil Rampakakis5, Allen Lehman6, Meagan Rachich6, Francois Nantel7 and Odalis Asin-Milan6, 1Centre de l'Ostoporose et de Rhumatologie de Qubec, Québec City, QC, Canada, 2Keystone Consulting Enterprises Inc., Toronto, ON, Canada, 3Department of Medicine, Eastern Health and Memorial University of Newfoundland, St John's, NL, Canada, 4University of Saskatchewan, Saskatoon, SK, Canada, 5JSS Medical Research, Montréal, QC, Canada, 6Janssen Inc., Toronto, ON, Canada, 7., Montréal, QC, Canada

    Background/Purpose: The aim of this analysis was to compare between enrolment periods RA treatment outcomes and frequency of treating to target, and to assess the…
  • Abstract Number: 1794 • ACR Convergence 2021

    Application of Treat to Target and Impact of Sustained Low Disease Activity or Remission on Function in Psoriatic Arthritis Patients

    Proton Rahman1, Regan Arendse2, Philip Baer3, Michel Zummer4, Emmanouil Rampakakis5, Allen Lehman6, Meagan Rachich6, Francois Nantel7 and Odalis Asin-Milan6, 1Department of Medicine, Eastern Health and Memorial University of Newfoundland, St John's, NL, Canada, 2University of Saskatchewan, Saskatoon, SK, Canada, 3Baer Weinberg MPC, Scarborough, ON, Canada, 4CH Maisonneuve-Rosemont, Montréal, QC, Canada, 5JSS Medical Research, Montréal, QC, Canada, 6Janssen Inc., Toronto, ON, Canada, 7., Montréal, QC, Canada

    Background/Purpose: Previous analyses have identified enrolment year as an independent predictor of real-world retention on anti-TNF treatment whereby patients enrolled in later periods were more…
  • Abstract Number: 0087 • ACR Convergence 2021

    TNF Inhibitors and the Risk of Adverse COVID-19 Outcomes in Patients with Immune-Mediated Inflammatory Disease: Pooled Data from Three Global Registries

    Zara Izadi1, Erica Brenner2, Satveer Mahil3, Nick Dand4, Zenas Yiu5, Mark Yates4, Ryan Ungaro6, Xian Zhang2, Manasi Agrawal6, Jean-Frederic Colombel7, Milena Gianfrancesco1, Kimme Hyrich5, Anja Strangfeld8, Loreto Carmona9, Elsa Frazão Mateus10, Saskia Lawson-Tovey5, Eva Klingberg11, Giovanna Cuomo12, Marta Caprioli13, Rene-Marc FLIPO14, Ana Rita Cruz-Machado15, Carolina Mazeda16, Rebecca Hasseli17, Alexander Pfeil18, Hanns-Martin Lorenz19, Laura Trupin20, Stephanie Rush1, Patricia Katz1, Gabriela Schmajuk1, Lindsay Jacobsohn21, Andrea Seet1, Samar Al Emadi22, Leanna Wise23, Emily Gilbert24, Ali Duarte-Garcia25, Maria Valenzuela-Almada26, Carolina Isnardi27, Rosana Quintana27, Enrique Soriano28, Tiffany Hsu29, Kristin D'Silva30, Jeffrey Sparks31, Naomi Patel30, Viviane de Souza32, Licia Maria Henrique Mota33, Ana Paula Reis34, Zachary S. Wallace35, Suleman Bhana36, Wendy Costello37, Rebecca Grainger38, Jonathan Hausmann39, Jean Liew40, Emily Sirotich41, Paul Sufka42, Philip Robinson43, Pedro Machado44, Christopher Griffiths45, Jonathan Barker4, Catherine smith4, Jinoos Yazdany1 and Michael Kappelman2, 1University of California San Francisco, San Francisco, CA, 2University of North Carolina at Chapel Hill, Chapel Hill, NC, 3St John’s Institute of Dermatology, London, United Kingdom, 4King's College London, London, United Kingdom, 5University of Manchester, Manchester, United Kingdom, 6Icahn School of Medicine at Mount Sinai, New York, NY, 7MD, New York, NY, 8Deutsches Rheuma-Forschungszentrum Berlin, Berlin, Germany, 9Instituto de Salud Musculoesqueltica (InMusc), Madrid, Spain, 10Liga Portuguesa Contra as Doenças Reumáticas (LPCDR), Lisbon, Portugal, 11University of Gothenburg, Gothenburg, Sweden and Sahlgrenska University Hospital, Gothenburg, Sweden, 12Università degli Studi della Campania Luigi Vanvitelli, Napoli, Italy, 13IRCCS Humanitas Research Hospital, Milan, Italy, 14Rheumatology Department, Lille University Hospital, Lille, France, 15Rheumatology Department, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Lisbon Academic Medical Center; Rheumatology Research Unit, Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal, 16Rheumatology Department - Centro Hospitalar do Baixo Vouga and Ibimed, Institute for Biomedicine, University of Aveiro, Aveiro, Portugal, 17Justus-Liebig-University Giessen, Bad Nauheim, Germany, 18Friedrich Schiller University Jena, Jena, Germany, 19University Hospital Heidelberg Germany, Heidelberg, Germany, 20UC San Francisco, San Francisco, CA, 21University of California San Francisco, Antioch, CA, 22Hamad medical corporation, Doha, Qatar, 23LAC+USC/Keck Medicine of USC, Pasadena, CA, 24Mayo Clinic, Jacksonville, FL, 25Mayo Clinic, Rochester, MN, 26Division of Rheumatology, Mayo Clinic, Rochester, MN, 27Argentine Society of Rheumatology, Buenos Aires, Argentina, 28Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, 29Brigham and Women's Hospital, Jamaica Plain, MA, 30Massachusetts General Hospital, Boston, MA, 31Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, 32UFJF, JUIZ DE FORA, Brazil, 33Universidade de Brasília, Brasilia, Brazil, 34Centro Universitrio de Braslia- UniCEUB, Brasilia, Brazil, 35Harvard Medical School, Boston, MA, 36Crystal Run Health, Montvale, NJ, 37Irish Children's Arthritis Network, Bansha, Ireland, 38University of Otago, Wellington, New Zealand, 39Boston Children's Hospital / Beth Israel Deaconess Medical Center, Cambridge, MA, 40Boston University, Boston, MA, 41McMaster University, Hamilton, ON, Canada, 42HealthPartners, Eagan, MN, 43University of Queensland School of Clinical Medicine, Brisbane, Australia, 44Centre for Rheumatology & Department of Neuromuscular Diseases, University College London, London, United Kingdom, 45University of Manchester, Manchester Centre for Dermatology Research, Manchester, United Kingdom

    Background/Purpose: While tumor necrosis factor inhibitors (TNFi) are widely prescribed globally due to their high efficacy across immune-mediated inflammatory diseases (IMIDs), the impact of COVID-19…
  • Abstract Number: 0802 • ACR Convergence 2021

    Infection in Rheumatoid Arthritis Patients Treated with Golimumab

    Louis Bessette1, Proton Rahman2, John Kelsall3, Jane Purvis4, Emmanouil Rampakakis5, Allen Lehman6, Meagan Rachich6, Francois Nantel7 and Odalis Asin-Milan6, 1Laval University, Québec City, QC, Canada, 2Department of Medicine, Eastern Health and Memorial University of Newfoundland, St John's, NL, Canada, 3Providence Health Care, Vancouver, BC, Canada, 4Peterborough Education, Peterborough, ON, Canada, 5JSS Medical Research, Montréal, QC, Canada, 6Janssen Inc., Toronto, ON, Canada, 7., Montreal, ON, Canada

    Background/Purpose: Biologic use in RA is a well-characterized risk factors for infections. The aim of this analysis was to characterize the incidence of infection in…
  • Abstract Number: 1830 • ACR Convergence 2021

    Discontinuation of Tumor Necrosis Factor Inhibitors in Psoriatic Arthritis and Psoriasis

    Sophia Wolfe1, Elizabeth Cheng2, Kavya Ganuthula1, Meika Fang3, Gail Kerr4, Jessica Walsh5, Elizabeth Chang6, Siba Raychaudhuri7, Kyle Brees2, Robert Dellavalle1, Andreas Reimold8 and Liron Caplan9, 1Rocky Mountain Regional VAMC/University of Colorado School of Medicine, Aurora, CO, 2Rocky Mountain Regional VAMC, Aurora, CO, 3David Geffen School of Medicine at UCLA/West Los Angeles Veterans Affairs Medical Center (VAMC), Los Angeles, CA, 4Washington D.C., Veterans Affairs Medical Center (VAMC)/Georgetown and Howard Universities, Washington, DC, 5Salt Lake City Veteran Affairs Medical Center (VAMC)/University of Utah Hospital, Salt Lake City, UT, 6Phoenix VAMC, Phoenix, AZ, 7Sacramento Veterans Affairs Medical Center (VAMC)/University of California-Davis Health, Davis, CA, 8University of Texas – Southwestern Medical Center/Dallas Veterans Affairs Medical Center (VAMC), Dallas, TX, 9Rocky Mountain Regional Veterans Affairs Medical Center (VAMC)/University of Colorado School of Medicine, Aurora, CO

    Background/Purpose: Psoriatic arthritis (PsA) is a chronic inflammatory disease of the joints and skin that affects 1/1000 people in the US. Tumor necrosis factor-alpha (TNF-α)…
  • Abstract Number: 0116 • ACR Convergence 2021

    COVID-19 mRNA Vaccine Side Effects Among Individuals with Rheumatic Disease

    Kaleb Michaud1, Adam Cornish2, Alison Freifeld1, Patricia Katz3 and Kristin Wipfler2, 1University of Nebraska Medical Center, Omaha, NE, 2FORWARD, The National Databank for Rheumatic Diseases, Omaha, NE, 3University of California San Francisco, San Francisco, CA

    Background/Purpose: Over 135 million Americans were fully vaccinated to COVID-19 by June 2021, yet there was a paucity of data on side effects for those…
  • Abstract Number: 0813 • ACR Convergence 2021

    Improvement in Clinical Disease Activity and Patient-Reported Outcomes After 6 Months of Treatment with Abatacept, Stratified by Line of Therapy, in Patients with RA: Results from a Large, US, National Observational Study

    Leslie Harrold1, Keith Wittstock2, Sheila Kelly2, Sang Hee Park2, Xue Han2, Ying Shan1, Carla Roberts-Toler1, Nicole Middaugh1 and Vadim Khaychuk2, 1CorEvitas, LLC, Waltham, MA, 2Bristol Myers Squibb, Princeton, NJ

    Background/Purpose: RA is more responsive to treatment in the early stages of disease, and early treatment may lead to better long-term outcomes.1,2 Data on the…
  • Abstract Number: 1831 • ACR Convergence 2021

    Predictors of Response, Adverse Events and Treatment Retention in Psoriatic Arthritis Patients Treated with Golimumab in a Prospective, Observational Registry

    Proton Rahman1, Isabelle Fortin2, Regan Arendse3, Derek Haaland4, Arthur Karasik5, Maqbool Sheriff6, Emmanouil Rampakakis7, Meagan Rachich8, Francois Nantel9, Allen Lehman8 and Odalis Asin-Milan8, 1Department of Medicine, Eastern Health and Memorial University of Newfoundland, St John's, NL, Canada, 2CREQ, Rimouski, QC, Canada, 3University of Saskatchewan, Saskatoon, SK, Canada, 4McMaster University, Hamilton, Ontario and The Waterside Clinic, Oro Medonte, ON, Canada, 5Arthur Karasik Medicine Professional Corporation, Toronto, ON, Canada, 6Nanaimo Regional Hospital, Nanaimo, BC, Canada, 7JSS Medical Research, Montréal, QC, Canada, 8Janssen Inc., Toronto, ON, Canada, 9., Montréal, QC, Canada

    Background/Purpose: The Biologic Treatment Registry Across Canada (BioTRAC) was a prospective, observational registry that enrolled psoriatic arthritis (PsA) patients treated with subcutaneous golimumab (GLM) between…
  • Abstract Number: 0190 • ACR Convergence 2021

    Long-term Safety of Canakinumab in Patients with Autoinflammatory Periodic Fever Syndromes – Interim Analysis of the RELIANCE Registry

    Jasmin Kuemmerle-Deschner1, Jorg Henes2, Birgit Kortus-Goetze3, Tilmann Kallinich4, Prasad T. Oommen5, Juergen Rech6, Frank Weller-Heinemann7, Gerd Horneff8, Ivan Foeldvari9, Aleš Janda10, Catharina Schuetz11, Frank Dressler12, Michael Borte13, Markus Hufnagel14, Axel Braner15, Florian Meier16, Michael Fiene17, Julia Weber-Arden18 and Norbert Blank19, 1Pediatric Rheumatology and Autoinflammatory Reference Center, University Children's Hospital Tuebingen, Tuebingen, Germany, 2University Hospital Tuebingen, Tuebingen, Germany, 3Division of Nephrology, University of Marburg, Marburg, Germany, 4Charité University Medicine, Nuremberg, Germany, 5Clinic of Pediatric Hematology, Oncology and Clinical Immunology, Heinrich-Heine-University Duesseldorf, Duesseldorf, Germany, 6Friedrich-Alexander University (FAU) Erlangen-Nuernberg and Universitaetsklinikum Erlangen, Department of Internal Medicine 3 - Rheumatology and Immunology, Germany, Erlangen, Germany, 7Klinikum Bremen-Mitte, Prof. Hess Kinderklinik, Bremen, Germany, 8Paediatric Rheumatology International Trials Organisation (PRINTO), Sankt Augustin, Germany, 9Hamburger Zentrum fuer Kinder- und Jugendrheumatologie, Hamburg, Germany, 10Department of Pediatrics, University Hospital Ulm, Ulm, Germany, 11Pediatrics, Medizinische Fakultaet Carl Gustav Carus, Technische Universitaet Dresden, Dresden, Germany, 12Division of Pediatric Pneumology, Allergology and Neonatology, Hannover Medical School, Hannover, Germany, 13ImmunoDeficiencyCenter Leipzig (IDCL), Hospital St. Georg gGmbH Leipzig, Leipzig, Germany, 14Division of Pediatric Infectious Diseases and Rheumatology, Department of Pediatrics and Adolescent Medicine, University Hospital Medical Center Freiburg, Medical Faculty, University of Freiburg, Freiburg, Germany, 15Department of Medicine II, Rheumatology, University Hospital Frankfurt, Germany, Frankfurt a.M., Germany, 161 Division of Rheumatology, University Hospital Frankfurt, Goethe University, Frankfurt am Main, Germany 2 Fraunhofer Institute for Molecular Biology and Applied Ecology IME, Project Group Translational Medicine and Pharmacology TMP, Frankfurt am Main, Germany, Frankfurt a.M., Germany, 17Department of Internal Medicine, District Hospital Demmin, Demmin, Germany, 18Novartis Pharma GmbH, Nuremberg, Germany, 19Rheumatology, University Hospital Heidelberg, Eppelheim, Germany

    Background/Purpose: Autoinflammatory periodic fever syndromes (PFS) are characterized by severe systemic and organ inflammation. In clinical trials, successful treatment was achieved with the interleukin-1β inhibitor…
  • Abstract Number: 0814 • ACR Convergence 2021

    Patient Characteristics, Efficacy, and Treatment Patterns of Tofacitinib Monotherapy in Patients with RA: Contextualization of Randomized Controlled Trial Results with Real-world Data

    Janet Pope1, Axel Finckh2, Lucia Silva-Fernández3, Peter Mandl4, Haiyun Fan5, Jose L Rivas6, Monica Valderrama6 and María Montoro6, 1University of Western Ontario, London, ON, Canada, 2University Hospital of Geneva, Geneve - Vesenaz, Switzerland, 3Hospital Universitari Son Espases, Palma de Mallorca, Spain, 4Division of Rheumatology, Medical University of Vienna, Vienna, Austria, 5Pfizer Inc, Collegeville, PA, 6Pfizer SLU, Madrid, Spain

    Background/Purpose: Randomized controlled trials (RCTs) have long been considered the gold standard for clinical research, but can be complemented with real-world data (RWD) to further…
  • Abstract Number: 1855 • ACR Convergence 2021

    Up-regulation of TNFα Gene in Peripheral Blood Is Useful for Predicting the Development of Exercise-induced Pulmonary Hypertension, Which Is Early Stage of Pulmonary Vascular Disease Associated with Systemic Sclerosis

    Yoshinobu Koyama1, Yoshiharu Sato2, Tatsuma Shoji2, Soichiro Fuke1, Takatsune Umayahara1 and Moe Sakamoto1, 1Japanese Red Cross Okayama Hospital, Okayama, Japan, 2DNA Chip Research Inc, Tokyo, Japan

    Background/Purpose: Pulmonary hypertension (PH) is prominent as a vascular involvement of systemic sclerosis (SSc), which remains a leading cause of death in spite of current…
  • Abstract Number: 0191 • ACR Convergence 2021

    Influence of Canakinumab Dosing on Long-term Efficacy and Safety in Patients with Cryopyrin-associated Periodic Syndromes (CAPS) – 30-months Interim Analysis of the RELIANCE Registry

    Jasmin Kuemmerle-Deschner1, Birgit Kortus-Goetze2, Prasad T. Oommen3, Aleš Janda4, Juergen Rech5, Tilmann Kallinich6, Frank Weller-Heinemann7, Gerd Horneff8, Ivan Foeldvari9, Catharina Schuetz10, Michael Borte11, Axel Braner12, Julia Weber-Arden13 and Norbert Blank14, 1Pediatric Rheumatology and Autoinflammatory Reference Center, University Children's Hospital Tuebingen, Tuebingen, Germany, 2Division of Nephrology, University of Marburg, Marburg, Germany, 3Clinic of Pediatric Hematology, Oncology and Clinical Immunology, Heinrich-Heine-University Duesseldorf, Duesseldorf, Germany, 4Department of Pediatrics, University Hospital Ulm, Ulm, Germany, 5Friedrich-Alexander University (FAU) Erlangen-Nuernberg and Universitaetsklinikum Erlangen, Department of Internal Medicine 3 - Rheumatology and Immunology, Germany, Erlangen, Germany, 6Charité University Medicine, Nuremberg, Germany, 7Klinikum Bremen-Mitte, Prof. Hess Kinderklinik, Bremen, Germany, 8Paediatric Rheumatology International Trials Organisation (PRINTO), Sankt Augustin, Germany, 9Hamburger Zentrum fuer Kinder- und Jugendrheumatologie, Hamburg, Germany, 10Pediatrics, Medizinische Fakultaet Carl Gustav Carus, Technische Universitaet Dresden, Dresden, Germany, 11ImmunoDeficiencyCenter Leipzig (IDCL), Hospital St. Georg gGmbH Leipzig, Leipzig, Germany, 12Department of Medicine II, Rheumatology, University Hospital Frankfurt, Germany, Frankfurt a.M., Germany, 13Novartis Pharma GmbH, Nuremberg, Germany, 14Rheumatology, University Hospital Heidelberg, Eppelheim, Germany

    Background/Purpose: The IL-1 inhibitor canakinumab (CAN) induces rapid remission of symptoms of CAPS (Cryopyrin-associated periodic syndromes), a monogenic autoinflammatory disease with severe systemic inflammation, both…
  • Abstract Number: 0817 • ACR Convergence 2021

    Biosimilar Infliximab Therapy in Rheumatoid Arthritis, Axial Spondyloarthritis and Psoriatic Arthritis: A Long-term Follow-up Study on Infliximab-naive Patients and Switched Patients from the Originator to the Biosimilar CT-P13

    Hubert MAROTTE1, Maryse Assing2, Nadir Mammar2, Yves Brault3 and Bruno Fautrel4, 1Rheumatology department - Unisersity Hospital of Saint-Etienne, Saint-Etienne, France, 2Inflammation & Immunology - Pfizer, Paris, France, 3Pfizer, Paris, France, 4Pitié Salpêtrière Hospital, APHP, Sorbonne Université, Paris, France

    Background/Purpose: ReFLECT study has been carried out to investigate real life use of CT-P13, the first monoclonal antibody biosimilar to infliximab (IFX) originator.Methods: ReFLECT is…
  • Abstract Number: 1880 • ACR Convergence 2021

    Description of an Internet-Based Cohort with a Self-Reported Diagnosis of Polyarteritis Nodosa

    Jason Springer1, Tanaz Kermani2, Dianne Shaw3, Kalen Young3, Cristina Burroughs4 and Peter Merkel5, 1Vanderbilt University Medical Center, Franklin, TN, 2University of California Los Angeles, West Hills, CA, 3Vasculitis Foundation, Kansas City, MO, 4Health Informatics Institute, Tampa, FL, 5University of Pennsylvania, Philadelphia, PA

    Background/Purpose: Polyarteritis nodosa (PAN) is form of medium-vessel vasculitis with an estimated annual incidence of 1 per million. The rarity of the disease makes traditional…
  • Abstract Number: 0734 • ACR Convergence 2020

    Differences and Similarities Between down Syndrome-associated Arthritis and Juvenile Idiopathic Arthritis in the New Childhood Arthritis and Rheumatology Research Alliance (CARRA) Registry

    Jordan Jones1, Chelsey Smith2, Daniel J Lovell3 and Mara Becker4, 1Children's Mercy Kansas City, Kansas City, MO, 2Children's Mercy Kansas City, Holden, MO, 3PRCSG, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 4Duke University School of Medicine, Durham, NC

    Background/Purpose: Down syndrome-associated arthritis (DA) is under-recognized with delay in diagnosis (1). The majority of those with DA present with polyarticular, rheumatoid factor (RF) and…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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