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Abstracts tagged "Raynaud’s phenomenon"

  • Abstract Number: 074 • 2023 Pediatric Rheumatology Symposium

    Clinical Characteristics of Juvenile Systemic Sclerosis in Korea: A 30-year Single Center Study

    Jieun Jeong1, Minji Kim1, Jiwon Jung2, Seon Hee Lim3 and Seong Heon Kim1, 1Department of Pediatrics, Seoul National University Children’s Hospital, Seoul, Republic of Korea, 2Department of Pediatrics, Asan Medical Center Children’s Hospital, University of Ulsan College of Medicine, Seoul, Republic of Korea, 3Department of Pediatrics, Pusan National University Children’s Hospital, Yangsan, Republic of Korea

    Background/Purpose: Juvenile systemic sclerosis (jSSc) is a rare autoimmune, chronic, multisystem, connective tissue disease characterized by progressive tissue fibrosis of the skin and internal organs.…
  • Abstract Number: 2036 • ACR Convergence 2022

    Development of Systemic Sclerosis in Patients with Primary Sjogren Syndrome and Raynauds Phenomenon

    Andres Martinez1, Julieta Morbiducci1, Constanza Arguissain1, Maria Tamborenea1, Marisel Bejarano2, Lucia Castorino1 and Anastasia Secco1, 1Rivadavia Hospital, Buenos Aires, Argentina, 2Rivadavia´s Hospital, Buenos Aires, Argentina

    Background/Purpose: Primary Sjögren's Syndrome (pSS) is an autoimmune disease, and Raynaud's Phenomenon (RP) is an extraglandular manifestation that can evolve into a systemic sclerosis-overlap syndrome.…
  • Abstract Number: 1061 • ACR Convergence 2022

    Safety and Tolerability of Aminaphtone in Systemic Sclerosis Patients: A Four-year Follow-up

    andrea cere, Emanuele Gotelli, Lercara Adriano, Carmen Pizzorni, sabrina Paolino, Alessandri Elisa, Maurizio Cutolo and Alberto Sulli, Laboratory of Experimental Rheumatology and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, IRCCS San Martino Polyclinic Hospital, Genova, Italy

    Background/Purpose: Recent studies proved that aminaphtone is an effective treatment for Raynaud's phenomenon (RP) secondary to systemic sclerosis (SSc). Laser Speckle Contrast Analysis (LASCA) further…
  • Abstract Number: 1529 • ACR Convergence 2022

    Clinical Nailfold Capillaroscopy Using Dinolite Microscope in Patients with Systemic Sclerosis

    Krishnasai Abhishek Madathanapalli1, Alyssa Williams2, Baran Ilayda Gunes2, Francis Perry Wilson3, John Pauling4, Robyn Domsic5, Lan Yu6 and Monique Hinchcliff7, 1University of Connecticut School of Medicine, Hartford, CT, 2Yale University, New Haven, CT, 3Yale school of medicine, New Haven, CT, 4North Bristol NHS Trust, Bristol, United Kingdom, 5University of Pittsburgh, Pittsburgh, PA, 6University of Pittsburgh School of Medicine, Pittsburgh, 7Yale School of Medicine, Westport, CT

    Background/Purpose: The clinical importance of nailfold capillaroscopy (NFC) has grown since its inclusion in the 2013 ACR/EULAR Classification Criteria for systemic sclerosis (SSc), yet few…
  • Abstract Number: 1557 • ACR Convergence 2022

    Microvascular Involvement in Behçet’s Disease: Study of Nailfold Capillaroscopy in Patients from a National Referral Center

    Belén Atienza-Mateo1, Alfonso del Peral-Fanjul2, Veronica Pulito-Cueto3, Diana Prieto-Peña1, Miguel Ángel González-Gay4 and Ricardo Blanco5, 1Research Group on Genetic Epidemiology and Atherosclerosis in Systemic Diseases and in Metabolic Bone Diseases of the Musculoskeletal System, IDIVAL; and Department of Rheumatology, Hospital Universitario Marqués de Valdecilla, Santander, Spain, 2Research Group on Genetic Epidemiology and Atherosclerosis in Systemic Diseases and Metabolic Bone Diseases of the Musculoskeletal System, IDIVAL, Santander, Spain, Spain, 3IDIVAL, Santander, Spain, 4Department of Medicine and Psychiatry, Universidad de Cantabria; Rheumatology Division, Hospital Universitario Marqués de Valdecilla; Research group on genetic epidemiology and atherosclerosis in systemic diseases and in metabolic diseases of the musculoskeletal system, IDIVAL, Santander, Spain. Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa, 5Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain

    Background/Purpose: Ocular and mucocutaneous manifestations of Behçet's disease (BD) are globally recognized and widely studied [Arthritis Rheumatol. 2019 Dec;71(12):2081-2089, Clin Exp Rheumatol. 2020 Sep-Oct;38 Suppl…
  • Abstract Number: 1773 • ACR Convergence 2022

    Epidemiology and Outcomes of Raynaud’s Phenomenon Hospitalizations in the US

    Rashmi Dhital1, Monica Guma2, Thuthiri Lwin3, Amar Suwal4 and Brian Pedersen1, 1UC San Diego, San Diego, CA, 2UCSD, La Jolla, CA, 3University of California San Diego, San Diego, CA, 4Reading Hospital, Tower Health, Reading, PA

    Background/Purpose: The prevalence of Raynaud's phenomenon (RP) in the general population is ~3-5%, of which 80–90% are primary. Autoimmune diseases are the most common causes…
  • Abstract Number: 0391 • ACR Convergence 2021

    High Frequency Ultrasound Imaging of Skin Thickness in Patients with Early Diffuse Cutaneous Systemic Sclerosis: An Objective Outcome Measure to Track Change over Time

    Elizabeth Marjanovic1, Calvin Heal1, Tonia Moore1, Joanne Manning2, Sarah Wilkinson1, Graham Dinsdale2, Mark Dickinson1, Jack Wilkinson1, Ariane Herrick3 and Andrea Murray1, 1University of Manchester, Manchester, United Kingdom, 2Salford Royal NHS Foundation Trust, Manchester, United Kingdom, 3University of Manchester, Salford, United Kingdom

    Background/Purpose: There are currently no validated objective measures of systemic sclerosis (SSc)-related skin thickening and this hampers clinical trials of potential new treatments. The modified…
  • Abstract Number: 0394 • ACR Convergence 2021

    Hyperspectral Imaging in Systemic Sclerosis-Raynaud Phenomenon

    Akash Gupta1, Shannon Teaw2, Alyssa Williams2, F. Perry Wilson3, Brandon Sumpio4, Bauer Sumpio4 and Monique Hinchcliff5, 1Department of Medicine, Yale University School of Medicine, New Haven, CT, 2Section of Rheumatology, Allergy & Immunology, Department of Medicine, Yale School of Medicine, New Haven, CT, 3Section of Nephrology, Department of Medicine, Yale School of Medicine, New Haven, CT; Department of Medicine Clinical and Translational Research Accelerator Yale School of Medicine, New Haven, CT, 4Division of Vascular Surgery, Department of Surgery, Yale School of Medicine, New Haven, CT, 5Yale School of Medicine, Westport, CT

    Background/Purpose: Raynaud phenomenon (RP), a microcirculatory, vasospastic disorder, may be primary or secondary to an autoimmune disease [e.g., an early indicator of systemic sclerosis (SSc)].…
  • Abstract Number: 0395 • ACR Convergence 2021

    RNA Polymerase III Autoantibody Levels and Risk of Systemic Sclerosis in Patients with Raynaud Phenomenon

    Megan Lockwood1, Yuqing Zhang2, Marcy Bolster1, Sara Schoenfeld1, Xiaoqing Fu1, Seth Brownmiller1, Ana Fernandes1 and Flavia Castelino1, 1Massachusetts General Hospital, Boston, MA, 2Massachusetts General Hospital, Quincy, MA

    Background/Purpose: Raynaud phenomenon is often the initial manifestation in systemic sclerosis (SSc) and can precede other SSc symptoms by years (1). Several SSc-specific autoantibodies are…
  • Abstract Number: 0399 • ACR Convergence 2021

    Nailfold Videocapillaroscopy Findings and Associations with Organ Involvement in Mixed Connective Tissue Disease

    Camille Kasser, Gonçalo Boleto, Yannick Allanore and Jerome Avouac, Université de Paris, Service de Rhumatologie, Hôpital Cochin, AP-HP.CUP, Paris, France

    Background/Purpose: Mixed connective tissue disease (MCTD) is a rare autoimmune condition characterized by Raynaud’s phenomenon, positivity of antibodies targeting the U1 small nuclear ribonucleoprotein particle…
  • Abstract Number: 0400 • ACR Convergence 2021

    Item Development for the Assessment of Systemic Sclerosis-associated Raynaud’s Phenomenon (ASRAP) Questionnaire

    John Pauling1, Lesley Ann Saketkoo2, Dinesh Khanna3, Christopher Denton4, Tracy Frech5, Ariane Herrick6, Laura Hummers7, Ami Shah8 and Robyn Domsic9, 1Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom, 2University Medical Center - Comprehensive Pulmonary Hypertension Center, New Orleans, LA, 3University of Michigan, Ann Arbor, MI, 4University College London Division of Medicine, Centre for Rheumatology and Connective Tissue Diseases, London, United Kingdom, 5University of Utah, Salt Lake City, UT, 6University of Manchester, Salford, United Kingdom, 7Johns Hopkins Univerisity, Baltimore, MD, 8Johns Hopkins Rheumatology, Baltimore, MD, 9University of Pittsburgh, Pittsburgh, PA

    Background/Purpose: The episodic and uniquely personalised nature of Raynaud’s phenomenon (RP) has led to reliance upon self-report to capture how patients ‘feel’ and ‘function’. Existing…
  • Abstract Number: 0401 • ACR Convergence 2021

    Item Reduction for the Assessment of Systemic Sclerosis-associated RAynaud’s Phenomenon (ASRAP) Questionnaire Using Data from the International Multicentre ASRAP Validation Study

    John Pauling1, Lan Yu2, Christopher Denton3, Tracy Frech4, Ariane Herrick5, Laura Hummers6, Lesley Ann Saketkoo7, Ami Shah8, Dinesh Khanna9 and Robyn Domsic2, 1Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom, 2University of Pittsburgh, Pittsburgh, PA, 3University College London Division of Medicine, Centre for Rheumatology and Connective Tissue Diseases, London, United Kingdom, 4University of Utah, Salt Lake City, UT, 5University of Manchester, Salford, United Kingdom, 6Johns Hopkins Univerisity, Baltimore, MD, 7University Medical Center - Comprehensive Pulmonary Hypertension Center, New Orleans, LA, 8Johns Hopkins Rheumatology, Baltimore, MD, 9University of Michigan, Ann Arbor, MI

    Background/Purpose: The Assessment of Systemic sclerosis-associated RAynaud’s Phenomenon (ASRAP) questionnaire is a novel patient-reported outcome (PRO) instrument devised to assess the severity and impact of…
  • Abstract Number: 0410 • ACR Convergence 2021

    Long-term Outcomes of Vascular Grafting of Medium Sized Vessels of the Wrist and Hand in Patients with Medication Refractory Systemic Sclerosis Related Raynaud’s Phenomenon at the University of Pennsylvania from 2009-2019

    Nora Sandorfi1, Chris Derk2 and Nora Hajnoczky3, 1University of Pennsylvania, Philadelphia, 2University of Pennsylvania, Philadelphia, PA, 3Albert Einstein Healthcare Network, Wallingford, PA

    Background/Purpose: Raynaud’s phenomenon (RP) seen in patients with an underlying autoimmune rheumatic disorder have both functional and structural dysfunction at the microvascular level and in…
  • Abstract Number: 0499 • ACR Convergence 2021

    Preliminary Assessment of Internal Reliability and Construct Validity of Long and Short-form Assessment of Systemic Sclerosis-associated RAynaud’s Phenomenon (ASRAP) Questionnaires

    John Pauling1, Lan Yu2, Christopher Denton3, Tracy Frech4, Ariane Herrick5, Laura Hummers6, Lesley Ann Saketkoo7, Ami Shah8, Dinesh Khanna9 and Robyn Domsic2, 1Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom, 2University of Pittsburgh, Pittsburgh, PA, 3University College London Division of Medicine, Centre for Rheumatology and Connective Tissue Diseases, London, United Kingdom, 4University of Utah, Salt Lake City, UT, 5University of Manchester, Salford, United Kingdom, 6Johns Hopkins Univerisity, Baltimore, MD, 7University Medical Center - Comprehensive Pulmonary Hypertension Center, New Orleans, LA, 8Johns Hopkins Rheumatology, Baltimore, MD, 9University of Michigan, Ann Arbor, MI

    Background/Purpose: The Assessment of Systemic sclerosis-associated RAynaud’s Phenomenon (ASRAP) questionnaire is a novel patient-reported outcome instrument devised to assess the severity and impact of SSc-RP.…
  • Abstract Number: 1365 • ACR Convergence 2021

    Release of High-Mobility Group Box-1 After an Raynaud’s Attack Potentially Leads to Fibroblast Activation and Interferon-γ Induced Protein-10 Production in Systemic Sclerosis

    Isabella Atzeni1, Yehya Al-Adwi2, Berber Doornbos-van der Meer2, Amel Eman Abdulle2, Anniek Van Roon2, Alja J. Stel2, Harry Van Goor2, Andries Smit2, Johanna Westra2 and Douwe J Mulder2, 1University of Groningen, University Medical Centre Groningen, Groningen, Groningen, Netherlands, 2University of Groningen, University Medical Centre Groningen, Groningen, Netherlands

    Background/Purpose: Raynaud’s Phenomenon (RP) leading to repetitive ischaemia and reperfusion (IR) stress, is the first recognisable sign of systemic sclerosis (SSc). Although RP has been…
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