Abstracts tagged "radiography and rheumatoid arthritis (RA)"

Abstract Number: 2007 • 2012 ACR/ARHP Annual Meeting
Radiological Peripheral Involvement At Hands, Feet and Hips in Young Adults with Polyarticular Idiopathic Juvenile Arthritis
Muriel Elhai¹, Ramin Bazeli², Veronique Freire², Antoine Feydy², Andre Kahan³, Chantal Job-Deslandre⁴ and Julien Wipff¹, ¹Rheumatology A, Paris Descartes University, Cochin Hospital, APHP, Paris, France, ²Radiology B, Paris Descartes University, Cochin Hospital, APHP, Paris, France, ³Service de Rhumatologie A, Rheumatology A, Paris Descartes University, Cochin Hospital, APHP, Paris, France, ⁴Service de Rhumatologie, Rheumatology A, Paris Descartes University, Cochin Hospital, APHP, Paris, France
Background/Purpose: Radiographic damage was recently considered to be a feature of poor prognosis in cases of polyarticular juvenile idiopathic arthritis (pJIA). However, most radiographic studies…
Abstract Number: 1849 • 2012 ACR/ARHP Annual Meeting
Value of Matrices Developed to Identify Early Rheumatoid Arthritis Patients with Rapid Radiographic Progression Despite Methotrexate Therapy: A Comparison of Their Performance in the Early Rheumatoid Arthritis Espoir Cohort
Bruno Fautrel¹, Benjamin Granger², Bernard Combe³, Francis Guillemin⁴, Alain Saraux⁵ and Xavier Le Loët⁶, ¹Rheumatology / GRC08-EEMOIS, APHP-Pitie Salpetriere Hospital / UPMC, Paris, France, ²Biostatistics - GRC08-EEMOIS, Université Pierre et Marie Curie - Paris 6 ; AP-HP, Paris, France, ³CHU Lapeyronie, Montpellier, France, ⁴Hopitaux de Brabois, Nancy, France, ⁵Department of rheumatology and unit of immunology (EA 2216), Université Brest Occidentale, Brest, France, ⁶Rheumatology, Department of Rheumatology, Rouen University Hospital & Inserm 905, Institute for Biomedical Research, University of Rouen, Rouen, France
Background/Purpose: Rapid radiographic progression (RRP) – i.e., increase of the Sharp/van der Heijde score (vSHS) ≥ 5 points during the 1st year – is a…
Abstract Number: 1794 • 2012 ACR/ARHP Annual Meeting
Matrix Metalloproteinase 3 and Acute Phase Proteins As Markers of Disease Activity and Radiographic Damage in Early Rheumatoid Arthritis
Mahmood MTM Ally¹, Bridget Hodkinson², Pieter W.A Meyer¹, Eustasius Musenge³, Mohammed Tikly⁴ and Ronald Anderson¹, ¹University of Pretoria, Pretoria, South Africa, ²Rheumatology, University of the Witwatersrand, Johannesburg, South Africa, ³University of Witwatersrand, Johannesburg, South Africa, ⁴Rheumatology, Division of Rheumatology, University of the Witwatersrand, Johannesburg, South Africa
Background/Purpose: Although matrix metalloproteinase-3 (MMP-3) is believed to be intimately involved in the immunopathogenesis of rheumatoid arthritis (RA), relatively little is known about its relationships…
Abstract Number: 1203 • 2012 ACR/ARHP Annual Meeting
High Expression of Genes in the Toll-Like Receptor and Interferon Pathways Are Associated with Radiographic Damage in African-Americans with ACPA-Positive RA
Maria I. Danila¹, A. D. Steg², Xiangqin Cui³, David Redden⁴, M. R. Johnson², Richard J. Reynolds⁵, D. van der Heijde⁶, Doyt L. Conn⁷, Beth L. Jonas⁸, Leigh F. Callahan⁹, Larry W. Moreland¹⁰, P. K. Gregersen¹¹ and S. Louis Bridges Jr.¹², ¹Med/Clinical Immun & Rheum, Univ of Alabama-Birmingham, Birmingham, AL, ²University of Alabama at Birmingham, ³Biostatistics, University of Alabama at Birmingham, ⁴Biostatistics, University of Alabama at Birmingham, Birmingham, AL, ⁵Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ⁶Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁷Rheumatology, Emory Univ School of Medicine, Atlanta, GA, ⁸Thurston Arthritis Research Ct, University of North Carolina at Chapel Hill, Chapel Hill, NC, ⁹Thurston Arthritis Res Ctr, University of North Carolina, Chapel Hill, NC, ¹⁰Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, ¹¹Genomics and Human Genetics, Feinstein Institute Medical Research and North Shore-Long Island Jewish Health System, Manhasset, NY, ¹²Division of Clinical Immunology & Rheumatology, University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: The clinical phenotype of rheumatoid arthritis (RA) ranges from mild joint inflammation to severe joint destruction, but molecular factors responsible for variability are incompletely…
Abstract Number: 1052 • 2012 ACR/ARHP Annual Meeting
Systematic Review of the Association Between Magnetic Resonance Imaging and Radiographic Detection of Erosions in Rheumatoid Arthritis
Ruben Tavares¹, Stephen R. Tytus², Karen A. Beattie³, Maggie Larche⁴, Naveen Parasu⁵, Colin E. Webber⁶, Lawrence E. Hart⁷ and Jonathan D. Adachi⁸, ¹McMaster University, Hamilton, ON, Canada, ²Northern Ontario School of Medicine, Sudbury, ON, Qatar, ³Medicine, McMaster University, Hamilton, ON, Canada, ⁴Rheumatology, McMaster University, Hamilton, ON, Canada, ⁵Radiology, Hamilton Health Sciences, Hamilton, ON, Canada, ⁶Department of Nuclear Medicine, Hamilton Health Sciences, Hamilton, ON, Canada, ⁷Medicine (Rheumatology), St. Joseph's Health Care, Hamilton, ON, Canada, ⁸St Joseph's Healthcare Hamilton, Hamilton, ON, Canada
Background/Purpose: In rheumatoid arthritis (RA), disparities between erosive bone lesion detection on magnetic resonance imaging (MRI) and X-ray require reconciliation. It is hypothesized that early…
Abstract Number: 1015 • 2012 ACR/ARHP Annual Meeting
Analysis of Integrated Radiographic Data for Two Long-Term, Open-Label Extension Studies of Adalimumab
Désirée van der Heijde¹, Robert Landewé², Edward Keystone³, Ferdinand C. Breedveld⁴, Shufang Liu⁵ and Neelufar Mozaffarian⁶, ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Int Med/Rheumatology, Academic Medical Center, Amsterdam, Netherlands, ³University of Toronto, Professor of Medicine, Toronto, ON, Canada, ⁴Dept of Rheumatology C1R, Leiden University Medical Center, Leiden, Netherlands, ⁵Immunology Development, Abbott, Abbott Park, IL, ⁶Abbott, Abbott Park, IL
Background/Purpose: The assessment of radiographic data from long-term studies in patients (pts) with rheumatoid arthritis (RA) poses a significant challenge, given the potential involvement of…
Abstract Number: 1016 • 2012 ACR/ARHP Annual Meeting
The Effect of Evaluation Variability At the Unit of Measurement On the Reliability of Omeract Ramris and Van Der Heijde-Modified Sharp Score
Ruben Tavares¹, Naveen Parasu², Karen Finlay³, Erik Jurriaans³, Hao Wu¹, Karen A. Beattie⁴, Maggie Larche⁵, Lawrence E. Hart⁶, William G. Bensen⁷, Raja S. Bobba⁵, Alfred A. Cividino⁴, Colin E. Webber⁸, Jean-Eric Tarride⁹ and Jonathan D. Adachi¹⁰, ¹McMaster University, Hamilton, ON, Canada, ²Radiology, Hamilton Health Sciences, Hamilton, ON, ³Radiology, Hamilton Health Sciences, Hamilton, ON, Canada, ⁴Medicine, McMaster University, Hamilton, ON, Canada, ⁵Rheumatology, McMaster University, Hamilton, ON, Canada, ⁶Medicine (Rheumatology), St. Joseph's Health Care, Hamilton, ON, Canada, ⁷Department of Medicine, Division of Rheumatology, St. Joseph's Hospital and McMaster University, Hamilton, ON, Canada, ⁸Department of Nuclear Medicine, Hamilton Health Sciences, Hamilton, ON, Canada, ⁹Clinical Epidemiology and Biostatistics (CE&B) and Economics, Programs for Assessment of Technology in Health (PATH) Research Institute, Hamilton, ON, Canada, ¹⁰St Joseph's Healthcare Hamilton, Hamilton, ON, Canada
Background/Purpose: The Outcome Measures in Rheumatology (OMERACT) Rheumatoid Arthritis Magnetic Resonance Imaging Score (RAMRIS) and van der Heijde-modified Sharp score (vdHSS) are recognized semi-quantitative measures…
Abstract Number: 1012 • 2012 ACR/ARHP Annual Meeting
Radiographic Deformity of the Foot Is Starting From the Early Stage of Rheumatoid Arthritis
Kenji Mamoto¹, Tatsuya Koike², Tadashi Okano¹, Atsuko Kamiyama², Yuko Sugioka¹, Masahiro Tada¹ and Hiroaki Nakamura¹, ¹Orthopedic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan, ²Rheumatosurgery, Osaka City University Graduate School of Medicine, Osaka, Japan
Background/Purpose: Foot deformities frequently arise in patients with rheumatoid arthritis (RA). It might cause gait dysfunction and lead to disability. However, the precise mechanism of…
Abstract Number: 981 • 2012 ACR/ARHP Annual Meeting
Aggregated Genetic Information Explains Variations On Hand Radiographic Scores in Rheumatoid Arthritis Patient
Jing Cui¹, Nancy A. Shadick², Katherine P. Liao³, Michael Weinblatt⁴, Robert M. Plenge⁵ and Elizabeth W. Karlson³, ¹Rheumatology, Brigham and Women's Hospital, Boston, MA, ²Rheumatology/Immunology, Brigham and Women's Hospital, Boston, MA, ³Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ⁴Rheumatology & Immunology, Brigham & Women's Hospital, Boston, MA, ⁵Division of Rheumatology, Immunology and Allergy and Division of Genetics, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA
Background/Purpose: Rheumatoid arthritis (RA) has an estimated heritability of approximately 60%. Joint destruction as a severity measure of RA is influenced by genetic factors, however…
Abstract Number: 812 • 2012 ACR/ARHP Annual Meeting
Intravenous Golimumab Inhibits Radiographic Progression and Maintains Clinical Efficacy and Safety in Patients with Active Rheumatoid Arthritis Despite Methotrexate Therapy: 1-Year Results of a Phase 3 Trial
Michael Weinblatt¹, Clifton O. Bingham III², Alan Mendelsohn³, Lenore Noonan⁴, Shihong Sheng⁵, Lilianne Kim⁶, Kim Hung⁶, Jiandong Lu⁶, Daniel Baker⁶ and Rene Westhovens⁷, ¹Rheumatology & Immunology, Brigham & Women's Hospital, Boston, MA, ²Department of Medicine, Johns Hopkins University, Baltimore, MD, ³Immunology, Janssen Research & Development, LLC, Spring House, PA, ⁴Immunology, Janssen Research & Development, LLC., Spring House, PA, ⁵Biostatistics, Janssen Research & Development, LLC, Spring House, PA, ⁶Janssen Research & Development, LLC, Spring House, PA, ⁷Rheumatology, University Hospital KU Leuven, Leuven, Belgium
Intravenous Golimumab Inhibits Radiographic Progression and Maintains Clinical Efficacy and Safety in Patients with Active Rheumatoid Arthritis Despite Methotrexate Therapy: 1-Year Results of a Phase…
Abstract Number: 766 • 2012 ACR/ARHP Annual Meeting
Anemia May Provide Clinically Relevant Information Beyond Conventional Disease Activity Assessment to Predict Radiographic Damage Progression in Rheumatoid Arthritis
Burkhard Moller¹, Frauke Förger², Peter M. Villiger³ and Axel Finckh⁴, ¹Rheumatology, Inselspital University Hospital, Bern, Switzerland, ²Rheumatology, Clinical Immunology and Allergology, Inselspital University Hospital of Bern, Bern, Switzerland, ³Rheumatology, Immunology and Allergology, University Hospital Bern, Bern, Switzerland, ⁴Rheumatology, Geneva University Hospitals, Geneva 14, Switzerland
Anemia may provide clinically relevant information beyond conventional disease activity assessment to predict radiographic damage progression in Rheumatoid ArthritisBurkhard Möller, Frauke Förger, Peter M. Villiger,…

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