Abstracts tagged "radiography and rheumatoid arthritis (RA)"

Abstract Number: 350 • 2013 ACR/ARHP Annual Meeting
Cortical Bone Density As Measured By Digital X-Ray Radiogrammetry Correlates with Radiographic Joint Damage In The Hands Within 1 Year In Psoriatic Arthritis
Agnes Szentpetery¹, Muhammad Haroon², Phil Gallagher³, Eric J. Heffernan⁴ and Oliver FitzGerald², ¹Rheumatology, Dublin Academic Medical Centre, St. Vincent's University Hospital, Dublin, Ireland, ²Department of Rheumatology, Dublin Academic Medical Centre, St. Vincent's University Hospital, Dublin, Ireland, ³Rheumatology, St. Vincent's University Hospital, Dublin, Ireland, ⁴Radiology, St. Vincent's University Hospital, Dublin, Ireland
Background/Purpose: Structural destruction in peripheral joints may occur over time in both PsA and RA. We previously reported that 47% of early PsA patients treated…
Abstract Number: 185 • 2013 ACR/ARHP Annual Meeting
No Secular Trends In Real Live Radiographic Progression Of Rheumatoid Arthritis In Recent Year
Miriam Gärtner¹, Farideh Alasti², Gabriela Supp¹, Josef S. Smolen³ and Daniel Aletaha¹, ¹Department of Internal Medicine III, Division of Rheumatology, Medical University of Vienna, Vienna, Austria, ²Department of Medicine III, Division of Rheumatology, Medical University of Vienna, Vienna, Austria, ³Department of Rheumatology, Medical University of Vienna and Hietzing Hospital, Vienna, Austria
Background/Purpose: Progression of joint damage as measured radiographically is a hallmark of rheumatoid arthritis (RA), and its reduction a key claim for traditional and novel…
Abstract Number: 2883 • 2013 ACR/ARHP Annual Meeting
Clinical Characteristics of Rheumatoid Arthritis Patients with Secondary Sjögren’s Syndrome and Association with Joint Damage
Lindsay E. Brown¹, Michelle A. Frits², Christine K. Iannaccone², Michael E. Weinblatt², Nancy A. Shadick³ and Katherine P. Liao⁴, ¹Internal Medicine, Massachusetts General Hospital, Boston, MA, ²Department of Medicine, Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, ³Rheumatology/Immunology, Brigham and Women's Hospital, Boston, MA, ⁴Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA
Background/Purpose: Secondary Sjögren's syndrome (sSS) is a common extra-articular manifestation of rheumatoid arthritis (RA). However, the clinical characteristics of this subgroup of patients are not…
Abstract Number: 2379 • 2013 ACR/ARHP Annual Meeting
In Rheumatoid Arthritis Patients With Stable Low Disease Activity On Methotrexate Plus Etanercept, Continuation Of Etanercept Is Superior Both Clinically and Radiographically To Discontinuation: Results From a Randomized, 3-Armed, Double-Blind Clinical Trial
Mikkel Østergaard¹, Marjatta Leirisalo-Repo², Till Uhlig³, Marita Jansson⁴, Esbjörn Larsson⁴, Fiona Brock⁵ and Ronald F. van Vollenhoven⁶, ¹Copenhagen University Hospital Glostrup, Copenhagen, Denmark, ²Department of Medicine, Division of Rheumatology, Helsinki University Central Hospital, Helsinki, Finland, ³Diakonhjemmet Hospital, Oslo, Norway, ⁴Pfizer AB, Sollentuna, Sweden, ⁵Quanticate, Hitchin, Hertfordshire, United Kingdom, ⁶Clinical Trials Unit Department of Rheumatology, The Karolinska Institute, Stockholm, Sweden
Background/Purpose: The randomized clinical trial “DOSERA” has shown that in patients receiving concomitant methotrexate (MTX) therapy, continuation of etanercept (ETN) at 50 mg wkly is…
Abstract Number: 1957 • 2013 ACR/ARHP Annual Meeting
Correlation Of Structural Abnormalities Of The Wrist and Metacarpophalangeal Joints Evaluated By High-Resolution Peripheral Quantitative Computed Tomography, 3 Tesla MRI and Conventional Radiographs In Rheumatoid Arthritis
Chan Hee Lee^1,2, Waraporn Srikhum^2,3, Andrew J. Burghardt⁴, Warapat Virayavanich^2,5, Thomas M. Link², John B. Imboden⁶ and Xiaojuan Li⁷, ¹Div Rheum Dept of Intl Med, NHIC Ilsan Hospital, Goyang-si, South Korea, ²Musculoskeletal Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, ³Department of Radiology, Thammasat University, Pathumthani, Thailand, ⁴Department of Radiology & Biomedical Imaging, Musculoskeletal Quantitative Imaging Research, UCSF, San Francisco, CA, ⁵Department of Radiology, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand, ⁶Department of Medicine, Division of Rheumatology, UCSF, San Francisco, CA, ⁷Department of Radiology and Biomedical Imaging, Musculoskeletal Quantitative Imaging Research, UCSF, San Francisco, CA
Background/Purpose: Early detection of joint inflammation and tissue damage are critical for patient management in rheumatoid arthritis (RA). High-resolution peripheral quantitative computed tomography (HR-pQCT) is…
Abstract Number: 1968 • 2013 ACR/ARHP Annual Meeting
A Novel, Feasible and Reliable Method Of Radiographic Scoring Of Rheumatoid Arthritis
Priyanka Vashisht¹, Harlan Sayles², Ted R. Mikuls² and Alan R. Erickson², ¹Creighton University Medical Center, Omaha, NE, ²Omaha VA Medical Center and University of Nebraska Medical Center, Omaha, NE
Background/Purpose: Radiographs of the hands and feet are used to evaluate the disease course of rheumatoid arthritis (RA) with several scoring systems previously described. However,…
Abstract Number: 1457 • 2013 ACR/ARHP Annual Meeting
Inhibitory Effect Of Abatacept On Joint Damage In Rheumatoid Arthritis Patients With Or Without Concomitant Methotrexate: A Retrospective Multicenter Analysis Of 12 Months Of Abatacept Treatment In Routine Clinical Practice
Isao Matsushita¹, Hiraku Motomura¹, Eiko Seki¹ and Tomoatsu Kimura², ¹Department of Orthopaedic Surgery, Faculty of Medicine, University of Toyama, Toyama, Japan, ²Department of rthopaedic Surgery, Faculty of Medicine, University of Toyama, Toyama, Japan
Background/Purpose: Abatacept is approved for use with or without methotrexate (MTX). The purpose of this study was to clarify the inhibitory effect of abatacept on…
Abstract Number: 1203 • 2012 ACR/ARHP Annual Meeting
High Expression of Genes in the Toll-Like Receptor and Interferon Pathways Are Associated with Radiographic Damage in African-Americans with ACPA-Positive RA
Maria I. Danila¹, A. D. Steg², Xiangqin Cui³, David Redden⁴, M. R. Johnson², Richard J. Reynolds⁵, D. van der Heijde⁶, Doyt L. Conn⁷, Beth L. Jonas⁸, Leigh F. Callahan⁹, Larry W. Moreland¹⁰, P. K. Gregersen¹¹ and S. Louis Bridges Jr.¹², ¹Med/Clinical Immun & Rheum, Univ of Alabama-Birmingham, Birmingham, AL, ²University of Alabama at Birmingham, ³Biostatistics, University of Alabama at Birmingham, ⁴Biostatistics, University of Alabama at Birmingham, Birmingham, AL, ⁵Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ⁶Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁷Rheumatology, Emory Univ School of Medicine, Atlanta, GA, ⁸Thurston Arthritis Research Ct, University of North Carolina at Chapel Hill, Chapel Hill, NC, ⁹Thurston Arthritis Res Ctr, University of North Carolina, Chapel Hill, NC, ¹⁰Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, ¹¹Genomics and Human Genetics, Feinstein Institute Medical Research and North Shore-Long Island Jewish Health System, Manhasset, NY, ¹²Division of Clinical Immunology & Rheumatology, University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: The clinical phenotype of rheumatoid arthritis (RA) ranges from mild joint inflammation to severe joint destruction, but molecular factors responsible for variability are incompletely…
Abstract Number: 1052 • 2012 ACR/ARHP Annual Meeting
Systematic Review of the Association Between Magnetic Resonance Imaging and Radiographic Detection of Erosions in Rheumatoid Arthritis
Ruben Tavares¹, Stephen R. Tytus², Karen A. Beattie³, Maggie Larche⁴, Naveen Parasu⁵, Colin E. Webber⁶, Lawrence E. Hart⁷ and Jonathan D. Adachi⁸, ¹McMaster University, Hamilton, ON, Canada, ²Northern Ontario School of Medicine, Sudbury, ON, Qatar, ³Medicine, McMaster University, Hamilton, ON, Canada, ⁴Rheumatology, McMaster University, Hamilton, ON, Canada, ⁵Radiology, Hamilton Health Sciences, Hamilton, ON, Canada, ⁶Department of Nuclear Medicine, Hamilton Health Sciences, Hamilton, ON, Canada, ⁷Medicine (Rheumatology), St. Joseph's Health Care, Hamilton, ON, Canada, ⁸St Joseph's Healthcare Hamilton, Hamilton, ON, Canada
Background/Purpose: In rheumatoid arthritis (RA), disparities between erosive bone lesion detection on magnetic resonance imaging (MRI) and X-ray require reconciliation. It is hypothesized that early…
Abstract Number: 1015 • 2012 ACR/ARHP Annual Meeting
Analysis of Integrated Radiographic Data for Two Long-Term, Open-Label Extension Studies of Adalimumab
Désirée van der Heijde¹, Robert Landewé², Edward Keystone³, Ferdinand C. Breedveld⁴, Shufang Liu⁵ and Neelufar Mozaffarian⁶, ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Int Med/Rheumatology, Academic Medical Center, Amsterdam, Netherlands, ³University of Toronto, Professor of Medicine, Toronto, ON, Canada, ⁴Dept of Rheumatology C1R, Leiden University Medical Center, Leiden, Netherlands, ⁵Immunology Development, Abbott, Abbott Park, IL, ⁶Abbott, Abbott Park, IL
Background/Purpose: The assessment of radiographic data from long-term studies in patients (pts) with rheumatoid arthritis (RA) poses a significant challenge, given the potential involvement of…
Abstract Number: 1016 • 2012 ACR/ARHP Annual Meeting
The Effect of Evaluation Variability At the Unit of Measurement On the Reliability of Omeract Ramris and Van Der Heijde-Modified Sharp Score
Ruben Tavares¹, Naveen Parasu², Karen Finlay³, Erik Jurriaans³, Hao Wu¹, Karen A. Beattie⁴, Maggie Larche⁵, Lawrence E. Hart⁶, William G. Bensen⁷, Raja S. Bobba⁵, Alfred A. Cividino⁴, Colin E. Webber⁸, Jean-Eric Tarride⁹ and Jonathan D. Adachi¹⁰, ¹McMaster University, Hamilton, ON, Canada, ²Radiology, Hamilton Health Sciences, Hamilton, ON, ³Radiology, Hamilton Health Sciences, Hamilton, ON, Canada, ⁴Medicine, McMaster University, Hamilton, ON, Canada, ⁵Rheumatology, McMaster University, Hamilton, ON, Canada, ⁶Medicine (Rheumatology), St. Joseph's Health Care, Hamilton, ON, Canada, ⁷Department of Medicine, Division of Rheumatology, St. Joseph's Hospital and McMaster University, Hamilton, ON, Canada, ⁸Department of Nuclear Medicine, Hamilton Health Sciences, Hamilton, ON, Canada, ⁹Clinical Epidemiology and Biostatistics (CE&B) and Economics, Programs for Assessment of Technology in Health (PATH) Research Institute, Hamilton, ON, Canada, ¹⁰St Joseph's Healthcare Hamilton, Hamilton, ON, Canada
Background/Purpose: The Outcome Measures in Rheumatology (OMERACT) Rheumatoid Arthritis Magnetic Resonance Imaging Score (RAMRIS) and van der Heijde-modified Sharp score (vdHSS) are recognized semi-quantitative measures…
Abstract Number: 1012 • 2012 ACR/ARHP Annual Meeting
Radiographic Deformity of the Foot Is Starting From the Early Stage of Rheumatoid Arthritis
Kenji Mamoto¹, Tatsuya Koike², Tadashi Okano¹, Atsuko Kamiyama², Yuko Sugioka¹, Masahiro Tada¹ and Hiroaki Nakamura¹, ¹Orthopedic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan, ²Rheumatosurgery, Osaka City University Graduate School of Medicine, Osaka, Japan
Background/Purpose: Foot deformities frequently arise in patients with rheumatoid arthritis (RA). It might cause gait dysfunction and lead to disability. However, the precise mechanism of…
Abstract Number: 981 • 2012 ACR/ARHP Annual Meeting
Aggregated Genetic Information Explains Variations On Hand Radiographic Scores in Rheumatoid Arthritis Patient
Jing Cui¹, Nancy A. Shadick², Katherine P. Liao³, Michael Weinblatt⁴, Robert M. Plenge⁵ and Elizabeth W. Karlson³, ¹Rheumatology, Brigham and Women's Hospital, Boston, MA, ²Rheumatology/Immunology, Brigham and Women's Hospital, Boston, MA, ³Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ⁴Rheumatology & Immunology, Brigham & Women's Hospital, Boston, MA, ⁵Division of Rheumatology, Immunology and Allergy and Division of Genetics, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA
Background/Purpose: Rheumatoid arthritis (RA) has an estimated heritability of approximately 60%. Joint destruction as a severity measure of RA is influenced by genetic factors, however…
Abstract Number: 812 • 2012 ACR/ARHP Annual Meeting
Intravenous Golimumab Inhibits Radiographic Progression and Maintains Clinical Efficacy and Safety in Patients with Active Rheumatoid Arthritis Despite Methotrexate Therapy: 1-Year Results of a Phase 3 Trial
Michael Weinblatt¹, Clifton O. Bingham III², Alan Mendelsohn³, Lenore Noonan⁴, Shihong Sheng⁵, Lilianne Kim⁶, Kim Hung⁶, Jiandong Lu⁶, Daniel Baker⁶ and Rene Westhovens⁷, ¹Rheumatology & Immunology, Brigham & Women's Hospital, Boston, MA, ²Department of Medicine, Johns Hopkins University, Baltimore, MD, ³Immunology, Janssen Research & Development, LLC, Spring House, PA, ⁴Immunology, Janssen Research & Development, LLC., Spring House, PA, ⁵Biostatistics, Janssen Research & Development, LLC, Spring House, PA, ⁶Janssen Research & Development, LLC, Spring House, PA, ⁷Rheumatology, University Hospital KU Leuven, Leuven, Belgium
Intravenous Golimumab Inhibits Radiographic Progression and Maintains Clinical Efficacy and Safety in Patients with Active Rheumatoid Arthritis Despite Methotrexate Therapy: 1-Year Results of a Phase…
Abstract Number: 766 • 2012 ACR/ARHP Annual Meeting
Anemia May Provide Clinically Relevant Information Beyond Conventional Disease Activity Assessment to Predict Radiographic Damage Progression in Rheumatoid Arthritis
Burkhard Moller¹, Frauke Förger², Peter M. Villiger³ and Axel Finckh⁴, ¹Rheumatology, Inselspital University Hospital, Bern, Switzerland, ²Rheumatology, Clinical Immunology and Allergology, Inselspital University Hospital of Bern, Bern, Switzerland, ³Rheumatology, Immunology and Allergology, University Hospital Bern, Bern, Switzerland, ⁴Rheumatology, Geneva University Hospitals, Geneva 14, Switzerland
Anemia may provide clinically relevant information beyond conventional disease activity assessment to predict radiographic damage progression in Rheumatoid ArthritisBurkhard Möller, Frauke Förger, Peter M. Villiger,…

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