Abstracts tagged "race/ethnicity"

Abstract Number: 0668 • ACR Convergence 2022
Differential Expression of Interferon Related Genes in SLE Patients of Asian and European Ancestries Abstract
Ian Rector¹, Prathyusha Bachali², Jinoos Yazdany³, Maria Dall'Era⁴, Amrie Grammer⁵ and Peter lipsky¹, ¹AMPEL Biosolutions, Charlottesville, VA, ²AMPEL BioSolutions, Redmond, WA, ³UCSF, San Francisco, CA, ⁴University of California, Division of Rheumatology, San Francisco, CA, ⁵AMPEL LLC, Charlottesville, VA
Background/Purpose: Interferon has been shown to play a role in the pathogenesis of SLE, but insufficient studies have been conducted into the differences in interferon…
Abstract Number: 1922 • ACR Convergence 2022
Multi-Joint Osteoarthritis Phenotypes by Race/Ethnicity and Sex: Preliminary Descriptive Data from the Johnston County Health Study
Sherwin Novin¹, Carolina Alvarez², Todd Schwartz³, Yvonne Golightly⁴ and Amanda Nelson², ¹University of North Carolina, Chapel Hill, NC, ²University of North Carolina at Chapel Hill, Chapel Hill, NC, ³University of North Carolina-Chapel Hill, Chapel Hill, NC, ⁴University of Nebraska Medical Center, Omaha, NE
Background/Purpose: To describe phenotypes of multi-joint osteoarthritis (MJOA) definitions by race/ethnicity and sex in a community-based cohort.Methods: The Johnston County Health Study (JoCoHS) is an…
Abstract Number: 0102 • ACR Convergence 2022
Impact of Racial Implicit Bias on Juvenile Idiopathic Arthritis Patients’ Treatment Recommendations
Alisha Akinsete¹, Illir Agalliu², Dawn Wahezi¹, Ellen Silvers², Onjona Hossain², Irene Blanco², Tamar Rubinstein³ and Cristina Gonzalez², ¹Children's Hospital at Montefiore, Bronx, NY, ²Albert Einstein College of Medicine, Bronx, NY, ³Albert Einstein College of Medicine, White Plains, NY
Background/Purpose: There are racial and ethnic disparities in juvenile idiopathic arthritis (JIA). Implicit bias can contribute to these health disparities through provider communication and medical…
Abstract Number: 0681 • ACR Convergence 2022
Antiphospholipid Antibodies and Incident Cardiovascular Events in a Diverse Population: Results from the Dallas Heart Study
Yu (Ray) Zuo¹, Sherwin Navaz¹, Wenying Liang¹, Chun Li², Colby Ayers³, Christine Rysenga¹, Alyssa Harbaugh¹, Gary Norman⁴, Elizabeth Solow³, Dami Akinmolayemi⁵, Anand Rohatgi³, David Karp⁶, Jason S Knight⁷ and James de Lemos³, ¹University of Michigan, Ann Arbor, MI, ²People's Hospital Peking University, Beijing, China, ³UT Southwestern Medical Center, Dallas, TX, ⁴Werfen, San Diego, ⁵Columbia University, New York, NY, ⁶UT Southwestern, Dallas, TX, ⁷University of Michigan, Division of Rheumatology, Ann Arbor, MI
Background/Purpose: While circulating antiphospholipid antibodies (aPL) are recognized as an important acquired risk factor for thrombotic events, the prevalence of aPL in the general population…
Abstract Number: 1935 • ACR Convergence 2022
Racial Disparities Influence Healthcare Utilization in Pediatric Rheumatology Clinic
William Soulsby¹ and Emily von Scheven², ¹University of California, San Francisco, San Francisco, CA, ²UCSF, San Francisco, CA
Background/Purpose: Racial disparities are prevalent in chronic illness, including pediatric rheumatic diseases. Prior work has investigated the impact of race on disease activity and damage…
Abstract Number: 0106 • ACR Convergence 2022
A Systematic Review of Racial and Ethnic Disparities in Disease Related Outcomes Among Patients with SLE
Teresa Semalulu¹, Keerthana Pasumarthi¹, Kevin Zhao¹, Rauda AlDhaheri¹, Nadine Akbar², KAREN BEATTIE¹ and KONSTANTINOS TSELIOS³, ¹McMaster University, Hamilton, ON, Canada, ²Humber River Hospital and University of Toronto, Toronto, ON, Canada, ³McMaster University, Population Health Research Institute, Hamilton, ON, Canada
Background/Purpose: Racialized patients and ethnic minorities have worse outcomes in SLE. This is likely related to a complex interplay between genetic and non-genetic factors. Numerous…
Abstract Number: 0874 • ACR Convergence 2022
A Tale of Many Canadas: Associations of Ethnicity with Juvenile Idiopathic Arthritis Categories and Disease Severity at Presentation in a Multicultural Universal Healthcare Setting: Results from ReACCh-Out
Stephanie Wong¹, Lori Tucker², Kristin Houghton³, David Cabral⁴, Mercedes Chan², Ross Petty³, Andrea Human², Kimberly Morishita³, Rae Yeung⁵, Kiem Oen⁶, Ciaran Duffy⁷, Roberta Berard⁸, Gaelle Chedeville⁹, Thomas Loughin¹⁰, Matthew Berkowitz¹⁰ and Jaime Guzman¹¹, ¹University of British Columbia, Vancouver, BC, Canada, ²British Columbia Children's Hospital, Vancouver, BC, Canada, ³University of British Columbia - Vancouver, Vancouver, BC, Canada, ⁴BC Children's Hospital and University of British Columbia, Vancouver, BC, Canada, ⁵The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada, ⁶University of Manitoba, Toronto, ON, Canada, ⁷University of Ottawa, Ottawa, ON, Canada, ⁸London Health Sciences Centre, London, ON, Canada, ⁹McGill University, Montréal, QC, Canada, ¹⁰Simon Fraser University, Vancouver, BC, Canada, ¹¹University of British Columbia and BC Children's Hospital, Vancouver, BC, Canada
Background/Purpose: The distribution of Juvenile Idiopathic Arthritis (JIA) categories and disease severity at presentation vary across countries, however it is unclear how much of this…
Abstract Number: 2045 • ACR Convergence 2022
Does Ancestry Influence Primary Sjögren’s Syndrome Phenotype or Severity?
Maxime Beydon¹, Marie Dulin², Raphaèle Seror³, Frederic Desmoulins², Xavier Mariette⁴ and Gaetane Nocturne⁵, ¹Université Paris Cité, Paris, France, ²Kremlin Bicêtre Hospital - APHP, Paris, France, ³University Hospital Paris-Saclay, Le Kremlin Bicêtre, France, ⁴Paris-Saclay University, Rueil Malmaison, Ile-de-France, France, ⁵APHP, Le Kremlin Bicêtre, France
Background/Purpose: It is well established that in systemic lupus erythematous (SLE), disease burden is higher in patients from African ancestry (AA) than in Caucasian patients.…
Abstract Number: 0108 • ACR Convergence 2022
Study of the Level of Antibody Response to COVID-19 Vaccine in a Minority Population with Rheumatological Disorders
Tanushree Bhatt, Snigdha Gadireddy, Pravash Budhathoki and Giovanni Franchin, Bronxcare Health System, Bronx, NY
Background/Purpose: Multiple studies have shown reduced immunogenicity of mRNA covid vaccines in patients with rheumatological disease. The waning antibody levels in this population group, whether…
Abstract Number: 0962 • ACR Convergence 2022
Variability in Racial Disparities in Pregnancy Outcomes in Women with SLE by Diagnosis Algorithm
Megan Clowse¹, Jim Oates², Katie Kirchoff², April Barnado³, Saira Sheikh⁴, Leslie Crofford³ and Amanda Eudy⁵, ¹Duke University, Durham, NC, ²Medical University of South Carolina, Charleston, SC, ³Vanderbilt University Medical Center, Nashville, TN, ⁴University of North Carolina at Chapel Hill, Chapel Hill, NC, ⁵Duke University, Raleigh, NC
Background/Purpose: Disparities in pregnancy outcomes among women with SLE remain understudied, with few available racially-diverse datasets. We previously validated algorithms to identify pregnancies in women…
Abstract Number: 2060 • ACR Convergence 2022
Increased Risk of Adverse Renal Outcomes in Patients of African Ancestry with Systemic Lupus Erythematosus (SLE) – Role of APOL1
Gul Karakoc, Ge Liu, Jorge Gamboa, Cecilia Chung, Jonathan Mosley, Michael Stein and Vivian Kawai, Vanderbilt University Medical Center, Nashville, TN
Background/Purpose: SLE disproportionately affects individuals of African (AA) compared to European ancestry (EA). In addition to a higher incidence, the disease is more severe in…
Abstract Number: 0112 • ACR Convergence 2022
What Drives Racial Disparities in Gout in the USA? – Population-Based, Sex-Specific, Casual Mediation Analysis
Natalie McCormick¹, Leo Lu², Chio Yokose³, amit johi⁴, Tony Merriman⁵, kenneth saag⁶, Yuqing Zhang⁷ and Hyon Choi⁸, ¹Massachusetts General Hospital, Boston, MA, ²Arthritis Research Canada, Vancouver, BC, Canada, ³Massachusetts General Hospital, Waltham, MA, ⁴Regeneron, Boston, MA, ⁵University of Otago, Dunedin, New Zealand, ⁶University of Alabama at Birmingham, Birmingham, AL, ⁷Massachusetts General Hospital, Quincy, MA, ⁸MASSACHUSETTS GENERAL HOSPITAL, Lexington, MA
Background/Purpose: Emerging US cohort data suggest gout and hyperuricemia impart larger burdens on adults self-reporting Black race, especially Black women, than those self-reporting White race.[1,2]…
Abstract Number: 1100 • ACR Convergence 2022
Racial Differences in Clinical Trial Perceptions Among a Large, Predominantly Black Cohort of Patients with Systemic Lupus Erythematosus in the Southeastern United States
Jessica Williams¹, Gaobin Bao¹, Charmayne Dunlop-Thomas², Cristina Drenkard², Kim Schofield¹ and S. Sam Lim², ¹Emory University School of Medicine, Atlanta, GA, ²Emory University, Atlanta, GA
Background/Purpose: Black patients have higher incidence and severity of systemic lupus erythematosus (SLE) and worse outcomes as compared to White patients, yet Black patients are…
Abstract Number: 2106 • ACR Convergence 2022
Disparities of African American Mortality Trends in South Carolina Lupus Cohort
Sean Carter¹, Dulaney Wilson¹, Samantha Minkin², David Dillon³, Baxter Murray¹ and Jim Oates¹, ¹Medical University of South Carolina, Charleston, SC, ²Vanderbilt University Medical Center, Nashville, TN, ³Rheumatology Associates of South Florida, Delray Beach, FL
Background/Purpose: SLE is a chronic autoimmune disorder associated with increased mortality compared to the general population; treatment for SLE has improved and survival rates have…
Abstract Number: 0115 • ACR Convergence 2022
Facilitators of Immunosuppressive Medication Adherence in Systemic Lupus Erythematosus: A Qualitative Study of Racial Minority Patients, Lupus Providers and Clinic Staff
Shannon Herndon¹, Amy Corneli², Carrie Dombeck³, Teresa Swezey³, Megan Clowse³, Jennifer Rogers⁴, Lisa Criscione-Schreiber², Rebecca Sadun³, Jayanth Doss³, Amanda Eudy⁵, Hayden Bosworth² and Kai Sun³, ¹Duke University Hospital, Durham, NC, ²Duke University School of Medicine, Durham, NC, ³Duke University, Durham, NC, ⁴Duke, Durham, NC, ⁵Duke University, Raleigh, NC
Background/Purpose: SLE disproportionately affects patients of color. Medication nonadherence is more common among patients of color with SLE and is associated with worse health outcomes.…

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