ACR Meeting Abstracts

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Abstracts tagged "pulmonary"

  • Abstract Number: 1835 • ACR Convergence 2022

    Clinical Features of Patients with Sarcoidosis and Concomitant Connective Tissue Disease

    Magdalena Harasimowicz1, Emily GIlbert2, Sarah Yi3 and Rochella Ostrowski4, 1Loyola University Medical Center Department of Internal Medicine, Chicago, IL, 2Loyola University Medical Center Division of Pulmonary and Critical Care Medicine, Maywood, IL, 3Loyola University Stritch School of Medicine, Maywood, IL, 4Loyola University Medical Center Division of Rheumatology, Maywood, IL

    Background/Purpose: Sarcoidosis is a multiorgan granulomatous disease with a prevalence of 60 per 100,000 in the United States.1 Given the low prevalence of both sarcoidosis…
  • Abstract Number: 0804 • ACR Convergence 2022

    Incidence and Risk Factors of Active Tuberculosis in Patients with Rheumatic Diseases Complicated with Tuberculosis Infection: A Multicenter Prospective Cohort Study

    Lifan Zhang1, yuchen liu2, xiaoqing zou3, shi chen2, yanan ma2, huimin ma4, qifei cao4, zhengrong yang4, Fengchun ZHANG5, Yan Zhao5, Xiaofeng Zeng6 and Xiaoqing Liu1, 1Division of Infectious Diseases, Department of Internal medicine, State Key Laboratory of Complex Severe and Rare Disease, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College; Clinical Epidemiology Unit, Peking Union Medical College, International Clinical Epidemiology Network; Center for Tuberculosis Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China, 2Division of Infectious Diseases, Department of Internal medicine, State Key Laboratory of Complex Severe and Rare Disease, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College; Peking Union Medical College Hospital, Peking Union Medical College, Beijing, China, 3Division of Infectious Diseases, Department of Internal medicine, State Key Laboratory of Complex Severe and Rare Disease, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College; School of Population Medicine and Public Health, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China, 4Division of Infectious Diseases, Department of Internal medicine, State Key Laboratory of Complex Severe and Rare Disease, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China, 5Peking Union Medical College Hospital, Beijing, China, 6Department of Rheumatology, Peking Union Medical College Hospital (PUMCH), Chinese Academy of Medical Sciences National Clinical Research Center for Dermatologic and Immunologic Diseases (NCRC-DID), Beijing, China

    Background/Purpose: China remains a high-burden country of both rheumatic disease (RD) and tuberculosis (TB) till today. Patients with RD are considered as a high-risk population…
  • Abstract Number: 1844 • ACR Convergence 2022

    Biological Therapy in Neurosarcoidosis: Study of 30 Patients from a Series of 234 Systemic Sarcoidosis from a University Hospital

    Alba Herrero-Morant1, David Martínez-López2, Lara Sánchez-Bilbao2, iñigo Gonzalez-Mazon2, José Luis Martín-Varillas3, Raúl fernández-ramón2, Carmen Alvarez Reguera2, Miguel Ángel González-Gay4 and Ricardo Blanco5, 1Hospital Universitario Marqués de Valdecilla, Ontinyent, Spain, 2Hospital Universitario Marqués de Valdecilla, Santander, Spain, 3Hospital de Laredo, Laredo, Cantabria, Spain, 4Department of Medicine and Psychiatry, Universidad de Cantabria; Rheumatology Division, Hospital Universitario Marqués de Valdecilla; Research group on genetic epidemiology and atherosclerosis in systemic diseases and in metabolic diseases of the musculoskeletal system, IDIVAL, Santander, Spain. Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa, 5Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain

    Background/Purpose: Neurosarcoidosis (NS) is a severe complication of sarcoidosis. NS may be classified according to several subtypes. Data on therapy, including biological therapy (BT) is…
  • Abstract Number: 0823 • ACR Convergence 2022

    Pulmonary Manifestations in VEXAS (Vacuoles, E1 Enzyme, X-linked, Autoinflammatory, Somatic) Syndrome: A Systematic Literature Review

    Koushan Kouranloo1, Athea Ashley2, Sizheng Zhao3 and Mrinalini Dey4, 1Liverpool University Hospitals NHS Foundation Trust, Liverpool, United Kingdom, 2School of Medicine, University of Liverpool, Liverpool, United Kingdom, 3University of Manchester, Liverpool, United Kingdom, 4Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool, United Kingdom

    Background/Purpose: VEXAS (vacuoles, E1 enzyme, X-linked, auto-inflammatory, somatic) syndrome is a newly described auto-inflammatory disease, characterised by somatic mutation of UBA1 [1]. A consistent feature…
  • Abstract Number: 1881 • ACR Convergence 2022

    Association Study Between anti-TIF1γ Antibody and Development of Neoplasia in Three Tertiary Hospitals

    Marina Pavía Pascual1, Isidro Jarque Canalias1, Jose Luis Morell2, Jesús Loarce Martos3, Lorena Montaño Tapia4, Olga Rusinovich1, Natalia de la Torre-Rubio1, Maria Machattou1, Pablo Navarro Palomo1, Maria Carmen Barbadillo Mateos1, Monica Fernandez Castro5, Blanca Garcia-Magallon1, Maria Hildegarda Godoy Tundidor1, Carolina Merino1, JESUS SANZ SANZ1, Jose Luis Andreu1 and Jose Campos1, 1Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain, 2Hospital Universitario Ramon y Cajal, Madrid, Spain, 3Hospital Universitario Ramón y Cajal, Madrid, Spain, 4Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Madrid, Spain, 5Puerta de Hierro Hospital, Madrid, Spain

    Background/Purpose: Anti-transcriptional intermediary factor 1γ (anti-TIF 1γ) antibody is robustly linked with malignancy-associated dermatomyositis (DM) in adults, but its specificity varies widely between series. TIF…
  • Abstract Number: 0944 • ACR Convergence 2022

    Inconsistent Family Planning Documentation in Women with Interstitial Pneumonia with Autoimmune Features (IPAF)

    Elena Joerns1, Brooke Mills2, Una Makris3, Traci Adams1 and Bonnie Bermas1, 1UT Southwestern, Dallas, TX, 2UT Southwestern Medical Center, Fort Worth, TX, 3UT Southwestern Medical Center and Dallas VA, Dallas, TX

    Background/Purpose: Family planning discussions improve pregnancy outcomes in women with interstitial lung disease (ILD). Women with interstitial pneumonia with autoimmune features (IPAF), a subset of…
  • Abstract Number: 1928 • ACR Convergence 2022

    Idiopathic Pulmonary Capillaritis Within the Spectrum of Pediatric Diffuse Alveolar Hemorrhage

    Angela Chun1, Tiphanie vogel1, Andrea Ramirez1, Marietta De Guzman2, Eyal Muscal1 and Manuel Silva-Carmona3, 1Baylor College of Medicine, Houston, TX, 2Baylor College of Medicine/ Texas Children's Hospital, Houston, TX, 3Baylor College of Medicine, Texas Children's Hospital, Houston, TX

    Background/Purpose: Diffuse alveolar hemorrhage (DAH) is a life-threatening syndrome with bleeding from the pulmonary microvasculature. It is classified as pulmonary capillaritis if histology shows neutrophilic…
  • Abstract Number: 1049 • ACR Convergence 2022

    Risk Stratification of Patients with Systemic Sclerosis-associated Pulmonary Arterial Hypertension in EUSTAR Using the Current and New Proposed Criteria

    Hilde Jenssen Bjørkekjær1, cosimo bruni2, PATRICIA E CARREIRA3, Paolo Airò4, CARMEN PILAR SIMEON5, Marie-Elise Truchetet6, Alessandro Giollo7, Alexandra Balbir-Gurman8, Mickaël MARTIN9, Chris Denton10, Armando Gabrielli11, Håvard Fretheim12, Imon Barua12, Helle Bitter13, Øyvind Midtvedt12, Kaspar Broch14, Arne Andreassen12, Yoshiya Tanaka15, Gabriela Riemekasten16, Ulf Müller-Ladner17, Marco Matucci-Cerinic2, Ivan Castellvi18, Elise Siegert19, Eric Hachulla20, Oliver Distler21 and Anna-Maria Hoffmann-Vold12, 1Department of Rheumatology, Hospital of Southern Norway, Kristiansand, Norway, Kristiansand, Norway, 2University of Florence, Florence, Italy, 3HOSPITAL 12 DE OCTUBRE, Madrid, Spain, 4Rheumatology and Clinical Immunology Unit, ASST Spedali Civili, Brescia, Italy, 5Hospital Vall D'Hebron, Barcelona, Spain, 6CHU de Bordeaux, Bordeaux, France, 7Rheumatology Section, Department of Medicine, University of Verona, Italy, Verona, Italy, 8Rheumatology Institute, Rambam Health Care Campus, Haifa, Israel, 9Poitiers's Universatory Hospital, Department of Internal Medicine, Poitiers, France, Mignaloux-Beauvoir, France, 10University College London, London, United Kingdom, 11Università Politecnica delle Marche, Ancona, Italy, 12Oslo University Hospital, Oslo, Norway, 13Sorlandet sykehus, Kristiansand, Norway, 14Oslo University Hospital, Rikshospitalet, Department of Cardiology, Oslo, Norway, Oslo, Norway, 15University of Occupational and Environmental Health, Kitakyusyu Fukuoka, Japan, 16University Clinic Schleswit-Holstein (UKSH), Luebeck, Germany, 17JLU Campus KK, Bad Nauheim, Germany, 18Hospital Universitari de la Santa Creu i Sant Pau, Vilafranca del Pened, Spain, 19Charité Hospital, Berlin, Germany, 20University of Lille, LILLE, France, 21Department of Rheumatology, University Hospital Zurich, University of Zurich, Zürich, Switzerland

    Background/Purpose: Pulmonary arterial hypertension (PAH) is a major clinical challenge in systemic sclerosis (SSc). A new definition for precapillary PH is proposed. Risk stratification is…
  • Abstract Number: 1941 • ACR Convergence 2022

    Pediatric Idiopathic Pulmonary Hemosiderosis – a Single-Center, Retrospective Study Comparing Use of Commonly Used Steroid-Sparing Agents

    Melissa Argraves1, Melissa Lerman1, Julie Chase2 and Samuel Goldfarb3, 1Children's Hospital of Philadelphia, Philadelphia, PA, 2University of Kentucky, Lexington, KY, 3University of Minnesota, Minneapolis, MN

    Background/Purpose: Idiopathic Pulmonary Hemosiderosis (IPH) is a rare, pediatric predominant condition causing episodic diffuse alveolar hemorrhage, which can be recurrent and life-threatening. Chronic steroid use…
  • Abstract Number: 1057 • ACR Convergence 2022

    Usefulness of REVEAL 2.0 Score as a Prognosis Tool of All-Cause Pulmonary Hypertension in Systemic Sclerosis Patients: A Multicentric Study

    Ivette Casafont-Solé1, Laura Calvo2, Anne Riveros-Frutos3, Carlos De la Puente Bujidos4, Pau Alcubilla5, Lourdes Mateo1 and Ivan Castellví6, 1Hospital Universitari Germans Trias i Pujol, Badalona, Spain, 2Hospital Universitario Ramon y Cajal, Madrid, Spain, 3Hospital Universitari Germans Trias i Pujol, Barcelona, Spain, 4Ramon y Cajal University Hospital, Madrid, Spain, 5Hospital Clínic de Barcelona, Barcelona, Spain, 6Hospital Universitari de la Santa Creu i Sant Pau, Barcelona, Spain

    Background/Purpose: Pulmonary arterial hypertension (PAH) leads to a progressive right heart failure and death.PAH is a leading cause of death in Systemic Sclerosis (SSc). To…
  • Abstract Number: 2160 • ACR Convergence 2022

    The Role of CCL21 in Serum Samples from Systemic Sclerosis Patients

    Henriette Didriksen1, Øyvind Molberg2, Adi Mehta3, Suzana Jordan4, Håvard Fretheim3, Einar Gude3, Thor Ueland3, Cathrine Brunborg3, Vyacheslav Palchevskiy5, Torhild Garen3, Øyvind Midtvedt3, Arne Andreassen3, Fridtjof Lund-Johansen3, Oliver Distler4, John Belperio5 and Anna-Maria Hoffmann-Vold3, 1Oslo University Hospital, Moss, Norway, 2Department of Rheumatology, Oslo University Hospital, Oslo, Norway, Oslo, Norway, 3Oslo University Hospital, Oslo, Norway, 4Department of Rheumatology, University Hospital Zurich, University of Zurich, Zürich, Switzerland, 5University of California Los Angeles, Los Angeles, CA

    Background/Purpose: Chemokines appear to be important for the pathogenesis of autoimmune diseases. Humans may generate antibodies targeting chemokines leading to inhibition of signaling and driving…
  • Abstract Number: 1058 • ACR Convergence 2022

    Clinical Characteristics and Survival of Combined Pulmonary Arterial Hypertension and Interstitial Lung Disease in Systemic Sclerosis

    Jessica Fairley1, Dylan Hansen2, Laura Ross3, Susanna Proudman4, Jo Sahhar5, Gene-Siew Ngian6, Jenny Walker7, Lauren Host8, Kathleen Morrisroe2, Diane Apostolopoulos9, Nava Ferdowsi2, Michelle Wilson9, Maryam Tabesh2, Wendy Stevens2 and Mandana Nikpour10, 1The University of Melbourne, Melbourne, Australia, 2St Vincent's Hospital Melbourne, Melbourne, Australia, 3The University of Melbourne at St. Vincent's Hospital, Brunswick, Australia, 4University of Adelaide, Medindie, Australia, 5Monash Health, Melbourne, Australia, 6Melbourne Health, Northcote, Australia, 7Royal Adelaide Hospital, Adelaide, Australia, 8Fiona Stanley Hospital, London, United Kingdom, 9Monash University, Melbourne, Australia, 10The University of Melbourne at St. Vincent's Hospital Melbourne, Melbourne, Australia

    Background/Purpose: Pulmonary arterial hypertension (PAH) and interstitial lung disease (ILD) are the leading causes of systemic sclerosis (SSc) associated death. There is increasing interest in…
  • Abstract Number: 2172 • ACR Convergence 2022

    Pulmonary Function in Patients Diagnosed of Early Systemic Sclerosis: 10 Years-Experience

    Samuel Leal Rodriguez1, Francisco Miguel Ortiz Sanjuan2, José Ivorra Cortés3, Laura Mas Sanchez3, Pablo Muñoz Martinez4, Carmen Riesco Bárcena5, Anderson Huaylla Quispe6, Cristobal Pavez Perales3, Inés Cánovas Olmos3, Luis Gonzalez Puig7, Elena Grau García3, Isabel Martínez-Cordellat3, Carmen Nájera Herranz3, Rosa Negueroles Albuixech3, JOSE ELOY OLLER RODRIGUEZ8, Elvira Vicens Bernabeu2, Alba Torrat Novés5, Daniel Ramos Castro3 and José andrés Román ivorra1, 1Hospital Universitari i Politécnic La Fe, València, Spain, 2Hospital Universitario de La Fe, València, 3Rheumatology Department. Hospital Universitario y Politécnico La Fe, València, Spain, 4Rheumatology Department. Hospital Universitario y Politécnico La Fe, Sagunto, Spain, 5Rheumatology Department. Hospital Universitario y Politécnico La Fe, València, 6Medicina, València, Spain, 7Hospital La Fe, Torrente, Valencia, Spain, 8Hospital Universitario de La Fe, València, Spain

    Background/Purpose: Interstitial lung disease (ILD) is a frequent complication of systemic sclerosis (SSc), often progressive and has a poor prognosis. A restrictive ventilatory defect could…
  • Abstract Number: 1090 • ACR Convergence 2022

    Pulmonary Function Testing (PFT) in Patients with Antineutrophil Cytoplasmic Antibodies (ANCA)-associated Vasculitis (AAV): Correlation with Radiologic Imaging

    Johannes Dieterich1, You-Shan Feng2, Juliane Mahrhold1, Abdallah El Rai3 and Bernhard Hellmich1, 1Department of Internal Medicine, Rheumatology and Immunology, Medius Kliniken, University of Tübingen, Kirchheim Teck, Germany, 2Institute for clinical Epidemiology and Biometry, University of Tübingen, Tübingen, Germany, 3Department of Radiology und Nuclear Medicine, Medius Kliniken, University of Tübingen, Nürtingen, Germany

    Background/Purpose: Although pulmonary manifestations occur frequently in AAV, empirical evidence of their impact on pulmonary function is scarce. This project analyzed PFT data from a…
  • Abstract Number: 2175 • ACR Convergence 2022

    Evaluation of the Distribution of Haemodynamic Parameters and Prognostic Impact in a Cohort of Patients with Systemic Sclerosis

    Zoe Brown1, Dylan Hansen2, Wendy Stevens2, Laura Ross1, Nava Ferdowsi2, Susanna Proudman3, Jenny Walker4, Jo Sahhar5, Gene-Siew Ngian6, Lauren Host7, Gabor Major8, Mandana Nikpour9 and Kathleen Morrisroe2, 1St Vincent's Hospital, Melbourne, Australia, 2St Vincent's Hospital Melbourne, Melbourne, Australia, 3University of Adelaide, Medindie, Australia, 4Flinders Medical Centre, Flinders University, Daw Park, Australia, 5Monash Health, Melbourne, Australia, 6Melbourne Health, Northcote, Australia, 7Fiona Stanley Hospital, London, United Kingdom, 8Hunter New England Health Service, Rankin Park - Newcastle, New South Wales, Australia, 9The University of Melbourne at St. Vincent's Hospital Melbourne, Melbourne, Australia

    Background/Purpose: Scleroderma (SSc) is a complex multisystem autoimmune disease, characterised by vasculopathy and fibrosis of skin and organs. Involvement of the cardiovascular system occurs frequently…
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