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Abstracts tagged "pulmonary"

  • Abstract Number: 0299 • ACR Convergence 2024

    Real-World Tolerability of Nintedanib in Connective Tissue Disease-Associated Interstitial Lung Disease

    Saloni Goyal, Briana DiSilvio and Joanna Marco, Allegheny Health Network, Pittsburgh, PA

    Background/Purpose: Nintedanib is an antifibrotic medication used to treat interstitial lung disease (ILD), including connective tissue disease-associated ILD (CTD-ILD). Clinical trials that led to its…
  • Abstract Number: 1114 • ACR Convergence 2024

    Nintedanib in Autoimmune Disease-related Interstitial Lung Disease: Real-life Effectiveness, Safety and Tolerance in a Spanish Multicenter Study

    paula pérez garcía1, Miriam Retuerto Guerrero2, yanira chuquimia mendoza3, Jesús Loarce4, Belén Atienza-Mateo5, Carolina Merino6, marina pavia pascual7, cristiana sieiro santos8, Clara Moriano9 and elvira Diez álvarez10, 1Complejo Asistencial Universitario de León, león, Spain, 2Complejo Asistencial Universitario de León, Leon, Spain, 3Complejo asistencial univeritario de león, león, Spain, 4Ramón y Cajal University Hospital, Madrid, Madrid, Spain, 5Division of Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Immunopathology group, Santander, Cantabria, Spain, 6Hospital Universitario Puerta de Hierro Majadahonda., Majadahonda (Madrid), Spain, 7Hospital General Universitario Gregorio Marañon, madrid, Spain, 8Rheumatology Department, Complejo Asistencial Universitario de León, León, Spain, Leon, Spain, 9Hospital León, LEON, Spain, 10Complejo Asistencial Universitario de Leon, Leon

    Background/Purpose: Interstitial lung disease (ILD) is a severe complication of autoimmune diseases (AD). In recent years, new strategies for the treatment of progressive pulmonary fibrosis…
  • Abstract Number: 2059 • ACR Convergence 2024

    The Rs35705950 Promoter Variant of Muc5b Is Associated with Usual Interstitial Pneumonia in Antisynthetase Syndrome

    Daphne Rivero Gallegos1, Mayra Mejía2, Karol J. Nava-Quiroz2, Heidegger N. Mateos-Toledo3, Héctor I. Rocha-González4, Juan C. Huerta-Cruz3, Espiridion Ramos-Martínez5, Gloria Pérez-Rubio3, Ingrid Fricke-Galindo3, Jorge Rojas-Serrano6 and Ramcés Falfán-Valencia3, 1INER, Ciudad de México, Mexico State, Mexico, 2INER, Mexico, Distrito Federal, Mexico, 3INER, Mexico City, Distrito Federal, Mexico, 4Instituto Politècnico Nacional, Mexico City, Distrito Federal, Mexico, 5UNAM, Ciudad de Mexico, Distrito Federal, Mexico, 6National Institute of Respiratory Diseases, Ismael Cosío Villegas, Mexico City, Mexico

    Background/Purpose: Rs35705950 variant in the MUC5B gene promoter is a critical genetic risk factor in idiopathic pulmonary fibrosis (IPF). It has been associated with usual…
  • Abstract Number: 0281 • ACR Convergence 2023

    Is There a Decreased Risk of Developing CF Arthropathy in CF Patients Undergoing Treatment That Targets the F508del Mutation?

    Kristin Schmiedeberg1, Anna-Lena Walter1, Lukas Joos1, Martin Brutsche1, Johannes von Kempis2 and Andrea Rubbert-Roth1, 1Cantonal Hospital St. Gallen, St. Gallen, Switzerland, 2Kantonsspital St. Gallen, Division of rheumatology and immunology, St. Gallen, Switzerland

    Background/Purpose: Cystic fibrosis (CF) is characterized by mutations within the CFTR (cystic fibrosis transmembrane conductance regulator) gene that result in a defect of the chloride…
  • Abstract Number: 1514 • ACR Convergence 2023

    Phase I Study to Evaluate the Safety of Allogeneic Bone Marrow Derived Mesenchymal Stem Cells for Interstitial Lung Disease in Patients with Connective Tissue Disorders

    Andy Abril1, Isabel Mira-Avendano2, Nisha Durand1, Hassan Baig1, augustine Lee1, Meghan Baer1 and Abba Zubair1, 1Mayo Clinic, Jacksonville, FL, 2University of Texas, Houston, TX

    Background/Purpose: Interstitial lung disease (ILD) is a leading cause of morbidity and mortality in connective tissue disorders (CTD) including rheumatoid arthritis, scleroderma and inflammatory myopathies.…
  • Abstract Number: 1927 • ACR Convergence 2023

    Manifestations, Management and Outcomes of Interstitial Lung Disease Associated with Anti-synthetase Syndrome: A Systematic Literature Review

    Koushan Kouranloo1, Mrinalini Dey2, Veronica Yioe3, Lisa G Spencer3 and Caroline V Cotton4, 1Rheumatology & Internal Medicine Trainee- Surrey, UK. Education fellow University of Liverpool, Liverpool, United Kingdom, 2Queen Elizabeth Hospital, London, United Kingdom; University of Liverpool, Liverpool, United Kingdom, 3Liverpool Regional Lung Disease Service, Aintree Hospital, Lower Lane, Liverpool, United Kingdom, 4Department of rheumatology, Liverpool University NHS Foundation Trust, Liverpool, United Kingdom

    Background/Purpose: Anti-synthetase syndrome (ASS) is a chronic autoimmune inflammatory condition, characterized by myositis, interstitial lung disease (ILD), arthritis, Raynaud's phenomenon and mechanic's hands. This systematic…
  • Abstract Number: 0358 • ACR Convergence 2023

    Baseline Clinical Features and Biomarker Profiles of the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Systemic Juvenile Idiopathic Arthritis Associated Lung Disease (SJIA-LD) Cohort

    Esraa Eloseily1, Autumn Clark1, Min-Lee Chang2, MaryEllen Riordan3, alan Russell4, Marc Natter5, Sherry Thornton6, Yukiko Kimura7 and Grant Schulert1, 1Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2Boston Children's Hospital, Boston, MA, 3Hackensack Meridian Health, Hackensack, NJ, 4Duke Clinical Research Institute, Duke, NC, 5Harvard Medical School, Boston, MA, 6Cincinnati Children's Hospital, Cincinnati, OH, 7Hackensack Meridian School of Medicine, New York, NY

    Background/Purpose: Systemic juvenile idiopathic arthritis (SJIA) associated lung disease (SJIA-LD) is an emerging and life-threatening clinical problem with urgent unmet needs including prevalence, pathogenesis, disease…
  • Abstract Number: 1522 • ACR Convergence 2023

    Treatment of Pulmonary Arterial Hypertension in Patients with Connective Tissue Diseases: A Meta-analysis

    Mustafa Erdogan1, Sinem Nihal Esatoglu2, Burcak Kilickiran Avci3 and Gulen Hatemi2, 1Marmara University - Pendik Training and Research Hospital, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey, 2Istanbul University-Cerrahpasa, Cerrahpasa Medical School, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey, 3Istanbul University-Cerrahpasa, Cerrahpasa Medical School, Department of Cardiology, Istanbul, Turkey

    Background/Purpose: Treatment options for pulmonary arterial hypertension (PAH) have expanded in the last two decades. However, evidence for the treatment of connective tissue disease-associated PAH…
  • Abstract Number: 1940 • ACR Convergence 2023

    A Single-center, Observational, Retrospective, Case Control Study of Rituximab for the Treatment of Interstitial Pneumonia Associated with Autoimmune Features

    Tegveer Sandhu1, Lea Meir2, Nicole Ng1, Lila Klein1, Jigna Zatakia1, Maria Padilla1 and Ioannis Tassiulas1, 1Icahn School of Medicine at Mount Sinai, New York, NY, 2Icahn School of Medicine, New York, NY

    Background/Purpose: Patients with interstitial lung diseases (ILD) and clinical features of autoimmunity who do not satisfy the classification criteria for a specific autoimmune rheumatic disease…
  • Abstract Number: 0409 • ACR Convergence 2023

    Prevalence of Pulmonary Manifestations in Patients with Newly Diagnosed Rheumatoid Arthritis, Psoriatic Arthritis, and Peripheral Spondyloarthritis

    Lone Winter1, Dirk Skowasch1, Marcel Weber1, Daniel Kütting1, Charlotte Behning2, Peter Brossart3, Simon Petzinna4 and Valentin Sebastian Schäfer3, 1University Hospital Bonn, Bonn, Germany, 2Institute of Medical Biometry, Informatics and Epidemiology, University Hospital of Bonn, Bonn, Germany, 3Clinic of Internal Medicine III, Department of Oncology, Hematology, Rheumatology and Clinical Immunology, University Hospital of Bonn, Bonn, Germany, 4Clinic of Internal Medicine III, Oncology, Hematology, Rheumatology and Clinical Immunology, University Hospital Bonn, Bonn, Germany

    Background/Purpose: Pulmonary impairment is a common, yet poorly understood, extraarticular manifestation in rheumatic diseases, which is often inadequately screened and managed. This can result in…
  • Abstract Number: 1530 • ACR Convergence 2023

    Outcomes in Patients with Systemic Sclerosis Following Lung Transplantation: An Italian Multicentre Experience

    Claudia Iannone1, Maria Rosa Pellico1, Letizia Corinna Corinna Morlacchi2, Valeria Rossetti2, Marco Vicenzi2, Paolo Airò3, Marta Saracco4, Annamaria iagnocco4, Lorenzo Beretta5, Adriana Severino5, Eleonora Zaccara6, paola Faggioli6, Fabio Cacciapaglia7, Stefano Stano8, Silvia Cavalli9, Antonina Minniti9, giorgia Trignani9, francesco Blasi5, Roberto F. Caporali10 and Nicoletta Del Papa11, 1ASST Gaetano Pini CTO, Milan, Italy, 2Policlinico di Milano, Milan, Italy, 3Rheumatology and Clinical Immunology, ASST Spedali Civili of Brescia, University of Brescia, Brescia, Italy, 4AO Mauriziano di Torino, Torino, Italy, 5Policlinico di Milano, Milano, Italy, 6Legnano-ASST-Ovest Milanese, Legnano, Italy, 7Rheumatology Unit, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari, Bari, Italy, 8Policlinico di Bari, Bari, Italy, 9ASST Gaetano Pini CTO, Milano, Italy, 10Department of Clinical Sciences and Community Health, University of Milan, and Department of Rheumatology and Medical Sciences, ASST Gaetano Pini-CTO, Milano, Italy, 11Scleroderma Clinic, Dipartimento di Reumatologia, ASST Gaetano Pini CTO, Milano, Italy

    Background/Purpose: Lung transplantation (LT) is gaining ground in managing advanced ILD in SSc patients. However, concerns remain among surgeons due to SSc's complexity, multiorgan involvement…
  • Abstract Number: 2010 • ACR Convergence 2023

    B-FROST: Chronic OBstructive Pulmonary Disease and Vertebral FRacture of OSTeoporotic Origin: Results of a Real-life Cohort

    Amine Mouamnia, Armentieres Hospital Center, Armentieres, France

    Background/Purpose: Chronic obstructive pulmonary disease (COPD) is a chronic disease of the airways. It is mainly caused by smoking. Active smoking is a risk factor…
  • Abstract Number: 0617 • ACR Convergence 2023

    Pulmonary Rehabilitation in Connective Tissue Disease-Related Interstitial Lung Diseases

    Rosemary Gedert1, Suiyuan Huang2, Maya Sabbagh2, Melissa McInroy2, Steven Huang2, Dinesh Khanna2 and Vivek Nagaraja3, 1University of Michigan, Onsted, MI, 2University of Michigan, Ann Arbor, MI, 3Mayo Clinic Arizona, Scottsdale, AZ

    Background/Purpose: Interstitial lung disease (ILD) is a common manifestation of connective tissue disease (CTD)1. Pulmonary rehabilitation (PR) can be utilized to improve dyspnea and quality…
  • Abstract Number: 1588 • ACR Convergence 2023

    Monocyte-derived Macrophages Accumulate in the Lungs in anti-MDA5+ Dermatomyositis with RP-ILD: Proinflammatory and Profibrotic Phenotype Revealed by Single-cell RNA Sequencing

    Xiaoya Pei1, Jia Shi2, Yangzhong Zhou2, Xiao Zhang2, Xiaoman Wang1, Mingwei Tang2, Shuang Zhou2, chanyuan wu2, Jinmin Peng3, Mengtao Li4, xiaofeng Zeng2, Jun Liu5, Houzao Chen1 and Qian Wang2, 1State Key Laboratory of Medical Molecular Biology, Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China, 2Department of Rheumatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China, 3Medical Intensive Care Unit, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China, 4Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China, 5State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, China

    Background/Purpose: Anti-melanoma differentiation-associated gene 5-positive dermatomyositis (anti-MDA5+ DM) is a rare inflammatory autoimmune disease with impressively life-threatening rapid progressive interstitial lung disease (RP-ILD). The mechanism…
  • Abstract Number: 2173 • ACR Convergence 2023

    Window of Opportunity in the Treatment of Rheumatoid Arthritis-Interstitial Lung Disease with Abatacept. National Multicenter Study of 509 Patients

    Ana Serrano-Combarro1, Belén Atienza-Mateo2, libe Ibarrola-Paino3, Ivette Casafont-Sole4, Rafael Benito Melero-Gonzalez5, Alba Perez Linaza6, Santos Castañeda7, Rafaela Ortega Castro8, Natalia Mena Vazquez9, Nuria Vegas Revenga10, Lucia Cristina Dominguez Casas11, Cilia Peralta12, Trinidad Pérez-Sandoval13, Lorena Perez-Albadalejo14, Ruben Lopez-Sanchez15, MARIA GUADALUPE MANZANO CANABAL16, Anahy Maria Brandy-Garcia17, Patricia Lopez-Viejo18, Gema Bonilla19, Olga Maiz-Alonso20, Carmen carrasco-Cubero21, Marta Garijo Bufort22, Mireia Moreno23, Ana Urruticoechea24, Sergio Ordonez-Palau25, Carmen Gonzalez-Montagut Gomez26, andrea Garcia-Valle27, Juan Ramon De Dios Jimenez De Aber28, Fernando Lozano29, Tomás Vazquez-Rodriguez30, Maria Martin-Lopez31, Juan Maria Blanco-Madrigal32, Delia Fernández-Lozano33, Ignacio Brana Abascal34, Jesus Loarce-Martos35, Emilio Giner-Serret36, Virginia Ruiz-Esquide37, Clara ventin-Rodriguez38, Marina Rodriguez-lopez39, Pablo Andujar-Brazal40, Julia Fernandez-Melon41, Lilian Maria Lopez42, carlos Fernandez-Diaz43, Javier Loricera44, Ivan Ferraz Amaro45, Diego Ferrer46, Ricardo Blanco47 and On behalf of the Collaborative Group Members48, 1Hospital Universitario Marques de Valdecilla, IDIVAL, Santander, Spain, 2Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, 3Hospital Universitario de Navarra, Pamplona, Spain, 4Hospital Universitari Germans Trias i Pujol, Badalona, Spain, 5CHU Vigo, O Carballino, Spain, 6SERV. REUMATOLOGIA, Cadiz, Spain, 7Hospital Universitario de la Princesa, Madrid, Spain, 8Hospital Reina Sofía, Cordoba, Spain, 9IBIMA, Málaga, Spain, 10Hospital Galdakao- Usansolo, Galdakao, Spain, 11Hospital Universtario San Agustin, Oviedo, Spain, 12Hospital Clínico Lozano Blesa, Zaragoza, Spain, 13Hospital de León, León, Spain, 14Division of Rheumatology, Hospital Universitario de Jaén, Jaén, Spain, 15Hospital Universitario de Gran Canaria Doctor Negrín, Las Palmas de Gran Canaria, Spain, 16CAZA, Salamanca, Spain, 17Hospital Germans Trias i Pujol, Badalona, Spain, 18Division of Rheumatology, Hospital Severo Ochoa, Leganéz, Spain, 19Department of Rheumatology, Hospital Clínico Universitario La Paz, Madrid, Spain, 20University Hospital Donostia, San Sebastian, Spain, 21Department of Rheumatology, Hospital Universitario de Badajoz, Badajoz, Spain, 22Hospital de Sagunto, Valencia, Spain, 23Parc Tauli Hospital Universitari, I3PT(UAB), Barcelona, Spain, 24Hospital Can Misses, Ibiza, Spain, 25H. Arnau de Vilanova, Lleida, Spain, 26H. Clínico Universitario de Valladolid, Valladolid, Spain, 27Division of Rheumatology, Complejo Asistencial Universitario de Palencia, Palencia, Spain, 28Hospital de Araba, Alava, Spain, 29Hospital Universitario 12 de Octubre, Madrid, Spain, 30Rheumatology, Complejo Hospitalario Universitario de Ferrol, A Coruña, Spain, 31Hospital 12 de Octubre, Madrid, Spain, 32Division of Rheumatology, H. Universitario de Basurto, Bilbao, Spain, 33Hospital de Mérida, Merida, Spain, 34Division of Rheumatology, Hospital Universitario Central de Asturias, Oviedo, Spain, 35Ramón y Cajal University Hospital, Madrid, Spain, 36Hospital Royo Villanova, Teruel, Spain, 37Hospital Clinic, Rheumatology, Barcelona, Spain, 38Division of Rheumatology, Hospital Universitario de A Coruña, A Coruña, Spain, 39Division of Rheumatology, Hospital Clínico Universitario de Santiago, La Coruna, Spain, 40Division of Rheumatology, Hospital Universitario Doctor Peset, Valencia, Spain, 41Division of Rheumatology, Hospital Universitario Son Espases, Palma de Mallorca, Spain, 42Division of Rheumatology, Hospital Universitario Son Llàtzer, Mallorca, Spain, 43Division of Rheumatology, Hospital Universitario Reina Sofía, Murcia, Spain, 44Hospital Universitario Marqués de Valdecilla, Santander, Spain, 45Hospital Universitario de Canarias, Santa Cruz de Tenerife, Spain, 46Division of Pneumology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, 47Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, 48Spanish Collaborative Group of Interstitial Lung Disease Associated with Rheumatoid Arthritis, Spain, Spain

    Background/Purpose: Interstitial lung disease (ILD) is a severe complication of rheumatoid arthritis (RA). Abatacept (ABA) has demonstrated efficacy in the treatment of RA-ILD, especially if…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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