ACR Meeting Abstracts

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Abstracts tagged "pulmonary"

  • Abstract Number: 0520 • ACR Convergence 2020

    Antiphospholipid Antibodies and Thrombotic Events in COVID-19 Patients Hospitalized in Medicine Ward

    Alexandre Le Joncour1, Corinne Frere1, Isabelle Martin-Toutain1, Paul Gougis1, Pascale Ghillani-Dalbin1, Georgina Maalouf1, Matheus Vieira1, Anne-Genevieve Marcelin1, Joe-Elie Salem1, Yves Allenbach2, David Saadoun3, Olivier Benveniste4 and Patrice Cacoub1, 1APHP, paris, France, 2Sorbonne Université, Paris, Ile-de-France, France, 3AP-HP, Groupe Hospitalier Pitié-Salpêtrière, Department of Internal Medicine and Clinical Immunology, F-75013, Paris, France, Centre national de références Maladies Autoimmunes et systémiques rares et Maladies Autoinflammatoires rares, PAris, France, 4Sorbonne Université, paris, France

    Background/Purpose: A high prevalence of thrombotic events has been reported in critically ill COVID-19 patients but data on the prevalence of thrombosis in ward patients…
  • Abstract Number: 1695 • ACR Convergence 2020

    Anti-Melanoma Differentiation Associated Protein 5 (MDA5) Positive Juvenile Dermatomyositis: Focus on the Lung

    David Moreno McNeill1, Miriah Gillispie-Taylor2, Kevin Baszis3, Edouard Sayad1, Manuel Silva Carmona1 and Tiphanie Vogel1, 1Baylor College of Medicine/Texas Children's Hospital, Houston, TX, 2Baylor College of Medicine, Houston, 3Washington Univ School of Medicine, St Louis, MO

    Background/Purpose: A subset of juvenile dermatomyositis (JDM), clinically amyopathic dermatomyositis (CADM), is uncommon and mainly described in adults. CADM is classically characterized by skin ulcerations,…
  • Abstract Number: 0785 • ACR Convergence 2020

    Identification of Recruited CCR2+ Inflammatory Monocytes in a Mouse Model of RA-associated Lung Disease with Potential Role for resolvin-D1 in Reducing Monocyte Inflammatory Responses

    Austin Barry1, Geoffrey Thiele1, Ted Mikuls1, Michael Duryee1, Amy Nelson1, Rohit Gaurav1, Bryant England1 and Jill Poole1, 1University of Nebraska Medical Center, Omaha, NE

    Background/Purpose: Patients with rheumatoid arthritis (RA) are at an increased risk for comorbid chronic lung disease, with premature mortality. Therapies for RA-associated lung disease are…
  • Abstract Number: 1908 • ACR Convergence 2020

    Establishment of iPSc and Differentiated Endothelial Cells of Systemic Sclerosis Associated Pulmonary Arterial Hypertension ; Functional and Molecular Analysis

    Yuki Kudo1, Masaru Kato2, Yuhei Shibata1, Michihito Kono2, Yuichiro Fujieda2, Olga Amengual2, Kenji Oku2 and Tatsuya Atsumi3, 1Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan, 2Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan, 3Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine, Hokkaido University, Sapparo, Hokkaido, Japan

    Background/Purpose: Pulmonary arterial hypertension (PAH) occurs either primarily or in association with other diseases such as connective tissue diseases. PAH associated with systemic sclerosis (SSc-PAH)…
  • Abstract Number: 0912 • ACR Convergence 2020

    Effectiveness of DETECT Algorithm in Japanese Systemic Sclerosis Patients with Old or New Hemodynamic Definition of Pulmonary Arterial Hypertension

    Takanori Ito1, Takehiro Nakai2, Genki Kidoguchi2, Sho Fukui2, Hiroki Ozawa2, Satoshi Kawaai2, Yukihiko Ikeda2, Hisanori Shimizu2, Yasuhiro Suyama3, Atsushi Nomura2, Hiromichi Tamaki1, Kenichi Yamaguchi2 and Masato Okada1, 1St. Luke's International Hospital, Tokyo, Japan, 2St. Luke's International Hospital, Chuo-ku, Tokyo, Japan, 3JR Tokyo General Hospital, Tokyo, Japan

    Background/Purpose: Systemic sclerosis-associated pulmonary arterial hypertension (SSc-PAH) has been known as a life-threatening manifestation in SSc. Earlier detection and subsequent interventions are important to improve…
  • Abstract Number: 1957 • ACR Convergence 2020

    A Single Cell Stromal Atlas Identifies Conserved Fibroblast Phenotypes Expanded in the Inflamed Synovium, Lung, Intestine, and Salivary Gland

    Ilya Korsunsky1, Kevin Wei2, Mathilde Pohin3, Edy Kim4, Jason Turner5, Saba Nayar6, Benjamin Fisher7, Karim Raza8, Matthias Friedrich9, Jennifer Marshall5, Adam Croft5, Mark Coles10, Andreas Frei11, Andrew Filer12, Francesca Barone5, Kara Lassen11, Fiona Powrie10, Christopher Buckley13, Michael Brenner2 and Soumya Raychaudhuri14, 1Brigham and Women's Hospital, Boston, MA, 2Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 3Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Science, Oxford, United Kingdom, 4Brigham and Women’s Hospital, Division of Pulmonary and Critical Care Medicine, Boston, MA, 5Rheumatology Research Group, Institute for Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Queen Elizabeth Hospital, Birmingham, United Kingdom, 6Institute for Inflammation and Ageing, University of Birmingham, Birmingham, United Kingdom, 7University Hospitals Birmingham NHS Foundation Trust-Birmingham, Birmingham, United Kingdom, 8Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, United Kingdom, 9Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Science, University of Oxford, Oxford, United Kingdom, 10Kennedy Institute of Rheumatology, University of Oxford, Oxford, United Kingdom, 11Roche Pharma Research and Early Development, Immunology, Infectious Diseases and Ophthalmology (I2O) Discovery and Translational Area, Roche Innovation Center Basel, Basel, Switzerland, 12Institute of Inflammation and Ageing, University of Birmingham, Birmingham, United Kingdom, 13University of Birmingham, Birmingham, United Kingdom, 14Brigham and Women’s Hospital and Harvard Medical School, Boston, MA

    Background/Purpose: Pro-inflammatory fibroblasts have been independently implicated in the pathogenesis of rheumatoid arthritis (RA), inflammatory bowel disease (IBD), interstitial lung disease (ILD), and Sjogren’s syndrome…
  • Abstract Number: 867 • 2019 ACR/ARP Annual Meeting

    Safety and Efficacy of B-cell Depletion with Rituximab for the Treatment of Systemic Sclerosis-associated Pulmonary Arterial Hypertension in a Multi-center NIH Clinical Trial

    Mark Nicolls1, David Badesch 2, Lorinda Chung 3, Robyn Domsic 4, Thomas Medsger 5, Ashley Pinckney 6, Lynette Keyes-Elstein 6, Carla D'Aveta 6, Meagan Spychala 6, R James White 7, Paul Hassoun 8, Fernando Torres 9, Jerry Molitor 10, Dinesh Khanna 11, Holden Maeker 12, Beverly Welch 13, Ellen Goldmuntz 14, Roham Zamanian 1 and -- On Behalf of ASC01 Investigators 15, 1Stanford University, Stanford, 2University of Colorado, Denver, 3Stanford University, Palo Alto, CA, 4University of Pittsburgh, Pittsburgh, PA, 5University of Pittsburgh, Pittsburgh, 6Rho Federal Systems, Durham, 7University of Rochester, Rochester, NY, 8Johns Hopkins School of Medicine, Baltimore, 9UT Southwestern, Dallas, 10University of Minnesota, University of Minnesota, 11Department of Medicine, University of Michigan, Ann Arbor, Michigan, USA, Ann Arbor, 12Stanford, Stanford, 13National Institute of Allergy and Infectious Diseases, NIH, Bethesda, 14NIAID, Washingto, DC, 15---, USA

    Background/Purpose: Pulmonary arterial hypertension (PAH) is a life-threatening complication of systemic sclerosis (SSc). Pre-clinical and clinical data have strongly implicated immune dysregulation and B cell…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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