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Abstracts tagged "pulmonary"

  • Abstract Number: 1370 • ACR Convergence 2021

    Complement Factor D and Factor H Represent Disease and Severity Biomarkers for Systemic Sclerosis Associated Pulmonary Arterial Hypertension (SSc-PAH)

    Roberta G Marangoni1, Changyong Feng1, Ashley Frazer-Abel2, Stephen Tomlinson3, Amy Wielgosz1, Katie Lutz4, Michael Pauciulo4, William Nichols4, V. Michael Holers5, Christopher Ritchlin6, R James White III1 and Benjamin Korman1, 1University of Rochester, Rochester, NY, 2University of Colorado Denver, Colorado, CO, 3Medical University of South Carolina, Charleston, SC, 4Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 5University of Colorado, Denver, CO, 6Division of Allergy, Immunology, and Rheumatology, School of Medicine and Dentistry, University of Rochester Medical Center, Rochester, NY

    Background/Purpose: Pulmonary arterial hypertension (PAH) is a severe vascular complication of systemic sclerosis (SSc) and a major cause of mortality. Despite significant advances in the…
  • Abstract Number: 1379 • ACR Convergence 2021

    Serum Levels of the Soluble Receptor for Advanced Glycation Endproducts Are Prospectively Associated with Pulmonary Arterial Hypertension in Systemic Sclerosis

    Isabella Atzeni1, Yehya Al-Adwi2, Berber Doornbos-van der Meer2, Anniek Van Roon2, Caroline Roozendaal1, Andries Smit2, Alja J. Stel2, Harry Van Goor2, Tji-Joong Gan1, Johanna Westra2 and Douwe J Mulder2, 1University of Groningen, University Medical Centre Groningen, Groningen, Groningen, Netherlands, 2University of Groningen, University Medical Centre Groningen, Groningen, Netherlands

    Background/Purpose: Interstitial lung disease (ILD) and pulmonary arterial hypertension (PAH) are the leading causes of death in Systemic Sclerosis (SSc). Markers for early detection of…
  • Abstract Number: 1385 • ACR Convergence 2021

    Overall Survival in Patients with Systemic Autoimmune Diseases Following Lung or Heart-Lung Transplantation at a Single High-Volume Academic Transplant Center: A Comparative Cohort Study

    Jason Melehani1, Shufeng Li2, Joshua Mooney3 and Lorinda Chung2, 1Stanford University, San Jose, CA, 2Stanford University, Palo Alto, CA, 3Stanford University, Stanford, CA

    Background/Purpose: Lung manifestations of systemic autoimmune diseases are a frequent cause of early death. For many patients, current treatments cannot arrest the inexorable progression to…
  • Abstract Number: 1386 • ACR Convergence 2021

    Measurement of TIMP-1 in Pulmonary Vessels May Be a Novel Marker of Reflecting mPAP in CTD-PH

    Shusaku Nakashima1, Kaori Ishikawa1, Kiyo Ueeda1, Tomohiro Kameda1, Hiromi Shimada1, Risa Wakiya1, Mansour mai1, Mikiya Kato1, Taichi Miyagi2, Koichi Sugihara1, Rina Semba1, Mao Mizusaki1 and Hiroaki Dobashi3, 1Kagawa University, Takamatsu, Japan, 2Kagawa University, Kidagun, Japan, 3Department of Internal Medicine, Division of Hematology, Rheumatology and Respiratory Medicine, Faculty of Medicine, Kagawa University, Kagawa, Japan

    Background/Purpose: CTD is a disease with immune abnormalities which could alter normal cytokine profile. CTD-PH has a different pathogenesis from that of iPAH, and immunosuppressive…
  • Abstract Number: 1662 • ACR Convergence 2021

    Unrecognised, Subclinical, Structural or Functional Lung Changes in Rheumatoid Arthritis Is Associated with a Higher Risk of Developing Serious Respiratory Tract Infection

    Benjamin Worcester1, Dorothy Wang2, Susan Morton3 and Michelle Leech4, 1Monash Health, Melbourne, Australia, 2Melbourne Health, Clayton, Australia, 3Monash Health, Clayton, Australia, 4Monash Medical Centre, Australia, Australia

    Background/Purpose: The incidence of lung disease within the rheumatoid arthritis is well described and likely underestimated. Additionally, RA patients are at higher risk for developing…
  • Abstract Number: 1855 • ACR Convergence 2021

    Up-regulation of TNFα Gene in Peripheral Blood Is Useful for Predicting the Development of Exercise-induced Pulmonary Hypertension, Which Is Early Stage of Pulmonary Vascular Disease Associated with Systemic Sclerosis

    Yoshinobu Koyama1, Yoshiharu Sato2, Tatsuma Shoji2, Soichiro Fuke1, Takatsune Umayahara1 and Moe Sakamoto1, 1Japanese Red Cross Okayama Hospital, Okayama, Japan, 2DNA Chip Research Inc, Tokyo, Japan

    Background/Purpose: Pulmonary hypertension (PH) is prominent as a vascular involvement of systemic sclerosis (SSc), which remains a leading cause of death in spite of current…
  • Abstract Number: 0084 • ACR Convergence 2021

    COVID-19 Pneumonia in Two Hospitals: Similar Outcomes Despite Differential Use of Tocilizumab

    Leanna Wise1, Lauren Mathias2, Wendy Mack2, Aarya Kafi3, Yash Kothari2, Omkar Rao3 and William Stohl4, 1LAC+USC/Keck Medicine of USC, Pasadena, CA, 2University of Southern California, Los Angeles, CA, 3University of California San Diego, San Diego, CA, 4University of Southern California Keck School of Medicine, Los Angeles, CA

    Background/Purpose: A substantial number of patients with COVID-19 pneumonia develop a hyperinflammatory state. The anti-IL-6 receptor (IL-6R) mAb tocilizumab (TCZ) has been used in such…
  • Abstract Number: 0150 • ACR Convergence 2021

    Clinical Characteristics and Quantitative CT Findings in Connective Tissue Disease-Associated Interstitial Lung Disease

    Sirus Jesudasen1, Badar Patel2, Kristin D'Silva1, Pietro Nardelli2, Ruben San José Estépar2, George Washko2, Raúl San José Estépar2, Farbod Rahaghi2 and Sydney Montesi1, 1Massachusetts General Hospital, Boston, MA, 2Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Precapillary Pulmonary Hypertension (PPH) is a known complication of connective tissue disease-associated interstitial lung disease (CTD-ILD) but at present requires right heart catheterization (RHC)…
  • Abstract Number: 0152 • ACR Convergence 2021

    Deep Learning-Derived Chest Radiograph Scores in COVID-19 in Rheumatic Disease Patients versus General Population Comparators

    Naomi Patel1, Kristin D'Silva1, Matthew Li1, Tiffany Hsu2, Michael Di Iorio3, Xiaoqing Fu1, Claire Cook4, Lauren Prisco5, Lily Martin6, Kathleen Vanni6, Alessandra Zaccardelli6, Yuqing Zhang7, Jayashree Kalpathy-Cramer1, Jeffrey Sparks6 and Zachary Wallace8, 1Massachusetts General Hospital, Boston, MA, 2Brigham and Women's Hospital, Jamaica Plain, MA, 3Brigham and Women's Hospital, Brookline, MA, 4Division of Rheumatology, Allergy, and Immunology, Mass General Hospital, Boston, MA, 5Brigham and Women's Hospital, Pound Ridge, MA, 6Brigham and Women's Hospital, Boston, MA, 7Massachusetts General Hospital, Quincy, MA, 8Massachusetts General Hospital, Newton, MA

    Background/Purpose: Patients with rheumatic diseases and COVID-19 may have higher risk of mechanical ventilation than those without rheumatic diseases. We compared COVID-19 lung disease between…
  • Abstract Number: L04 • ACR Convergence 2020

    Influenza Adverse Events in Patients with Rheumatoid Arthritis in the Tofacitinib Clinical Program

    Kevin L Winthrop1, Arne Yndestad2, Dan Henrohn3, Hyejin Jo4, Sara Marsal5, Maria Galindo6, Annette Diehl7, Andrea B Shapiro8 and Stanley B Cohen9, 1Oregon Health & Science University, Portland, OR, 2Pfizer Inc, Oslo, Norway, 3Pfizer Inc, Sollentuna, Sweden, 4Syneos Health, Raleigh, NC, 5Vall d’Hebron Hospital, Barcelona, Spain, 6Rheumatology Unit, Hospital Universitario 12 de Octubre, Madrid, Spain, 7Pfizer Inc, Collegeville, PA, 8Pfizer Inc, Peapack, NJ, 9Metroplex Clinical Research Center, Dallas, TX

    Background/Purpose: Patients (pts) with RA have increased susceptibility to seasonal influenza and its complications.1 The COVID-19 pandemic highlights the need to understand acute respiratory RNA…
  • Abstract Number: 1051 • ACR Convergence 2020

    Rituximab for Interstitial Pneumonia with Autoimmune Features at Two Academic Medical Centers

    Kristin D'Silva1, Iazsmin Bauer Ventura2, Marcy Bolster3, Flavia Castelino4, Amita Sharma1, Brent Little1, Ayodeji Adegunsoye2, Mary Strek2, Sydney Montesi1 and Hyon Choi5, 1Massachusetts General Hospital, Boston, MA, 2University of Chicago, Chicago, IL, 3Massachusetts General Hospital, Concord, MA, 4Massachusetts General Hospital/Harvard Medical School, Boston, MA, 5Massachusetts General Hospital, Department of Medicine, Division of Rheumatology, Lexington, MA

    Background/Purpose: Many patients with interstitial lung disease (ILD) have autoimmune features without a distinct rheumatic disease and are thus designated as having interstitial pneumonia with…
  • Abstract Number: 0015 • ACR Convergence 2020

    COVID -19 Lung Inflammation – What Have We Learnt so Far ?

    Sriya Gokaraju1, Maria Darda2, Vinod Vijayaraghavan Nalini Warrier3, Irina Duta3, Fiona Hayes3, Yasser Ahmed4 and Gouri Koduri3, 1Southend University Hospital NHS Trust, Essex, United Kingdom, 2Southend University Hospital NHS Trust, Essex, United Kingdom, 3Southend University Hospital NHS Trust, Essex, United Kingdom, 4Southend University Hospital, Essex, United Kingdom

    Background/Purpose: The SARS CoV-2 pandemic has inspired new interest in understanding the fundamental pathology of pneumonia and Acute Respiratory Distress Syndrome (ARDS). SARS CoV-2 in…
  • Abstract Number: 1052 • ACR Convergence 2020

    Connective Tissue Disease-Related Interstitial Lung Disease in American Indian/Alaska Native People in Alaska

    Joanna Marco1 and Elizabeth Ferucci2, 1University of Washington, Seattle, WA, 2Alaska Native Tribal Health Consortium, Anchorage, AK

    Background/Purpose: Many connective tissue diseases are known to cause interstitial lung disease (ILD). American Indian/Alaska Native (AI/AN) populations have higher prevalence and severity of a…
  • Abstract Number: 0279 • ACR Convergence 2020

    Pulmonary Involvement in a Single Center Cohort of Patients with Systemic Lupus Erythematosus

    Naci Senkal1, Esen Kiyan2, Elif Kocasoy-Orhan3, Ali Demir4, Mehmet Aydogan5, Yasemin Yalcinkaya6, Ahmet Gul6, Murat Inanc7, Mahdume Lale Öcal6 and Bahar Artım-Esen6, 1Department of Internal Medicine, Istanbul Faculty of Medicine, Istanbul University, İstanbul, Turkey, 2Department of Chest Disease, Istanbul Faculty of Medicine, Istanbul University, İstanbul, Turkey, 3Department of Neurology, Istanbul Faculty of Medicine, Istanbul University, İstanbul, Turkey, 4Fulya Radiologic Imaging Center, İstanbul, Turkey, 5Department of Cardiology, Istanbul Faculty of Medicine, Istanbul University, İstanbul, Turkey, 6Department of Rheumatology, Istanbul Faculty of Medicine, Istanbul University, İstanbul, Turkey, 7Department of Rheumatology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey

    Background/Purpose: The prevalence of SLE pulmonary involvement varies depending on several factors, including diagnostic methods. In this study, we sought to determine the frequency of…
  • Abstract Number: 1200 • ACR Convergence 2020

    Serum Anti-PAD4 and Anti-PAD3/4XR Antibodies in Rheumatoid Arthritis Associated-Interstitial Lung Disease Are Associated with Better Lung Function

    Tim Wilson1, Joshua Solomon2, Jeffrey Swigris2, Erika Darrah3 and M Kristen Demoruelle1, 1University of Colorado, Denver, CO, 2National Jewish Health, Denver, CO, 3Division of Rheumatology, Johns Hopkins University, Baltimore, MD

    Background/Purpose: Rheumatoid arthritis (RA) associated-interstitial lung disease (ILD) affects approximately 10% of RA patients. It is a leading cause of morbidity and mortality, which is…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].

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