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Abstracts tagged "Psoriatic arthritis"

  • Abstract Number: 1336 • ACR Convergence 2020

    Bone Mineral Density, Trabecular Bone Score and Proximal Femur 3D-DXA Analysis in Psoriatic Diseases

    Eric Toussirot1, Renaud Winzenrieth2, Maxime Desmarets3, Daniel Wendling4, Francois Aubin5 and Gilles Dumoulin6, 1CIC biotherapies, Besançon University Hospital, Besançon, France, 2GALGO medical, Barcelona, Spain, 3INSERM CIC-1431, Besancon, France, 4CHU Besançon, department of rheumatology, Besancon, France, 5Dermatology, Besancon, France, 6Laboratoire de Biochimie Médicale, UF de Biochimie Endocrinienne et Métabolique, Besancon, France

    Background/Purpose: current data regarding areal bone mineral density (aBMD) in patients with psoriasis (PsO) or psoriatic arthritis (PsA) are conflicting. Results on Trabecular Bone Score…
  • Abstract Number: 1368 • ACR Convergence 2020

    Proportions of Patients Achieving a Minimal Disease Activity State upon Treatment with Tildrakizumab in a Psoriatic Arthritis Phase 2b Study

    Peter Nash1, Michael Luggen2, Ferran J. García Fructuoso3, Richard Chou4, Alan Mendelsohn5, Stephen Rozzo5 and Iain McInnes6, 1School of Medicine Griffith University, Brisbane, Queensland, Australia, 2University Hospital/University of Cincinnati College of Medicine, Cincinnati Rheumatic Disease Study Group, Inc, Cincinnati, OH, 3Hospital CIMA Sanitas, Barcelona, Spain, 4University at Buffalo, School of Medicine and Biomedical Sciences, Amherst, NY, 5Sun Pharmaceutical Industries, Inc., Princeton, NJ, 6Institute of Infection, Immunity, and Inflammation, University of Glasgow, Glasgow, United Kingdom

    Background/Purpose: Tildrakizumab (TIL) is a high-affinity anti–interleukin-23p19 monoclonal antibody approved in the US, EU, and Australia to treat moderate to severe plaque psoriasis.1 A randomized,…
  • Abstract Number: 1771 • ACR Convergence 2020

    Fertility and Pregnancy Outcomes in Women with Spondyloarthritis: A Systematic Review and Meta-analysis

    Sabrina Hamroun1, Aghilès Hamroun2, Jean-Joël Bigna3, Frauke Foerger4, Edem Allado5 and Anna Molto1, 1Rheumatology Department, Cochin Hospital, Paris, Paris, France, 2Lille University, Faculty of Medicine, Lille, France, Lille, France, 3School of Public Health, Faculty of Medicine, University of Paris Sud XI, Le Kremlin-Bicêtre, France, Paris, France, 4University Hospital and University of Bern, Bern, Switzerland, Bern, Switzerland, 5Rheumatology Department, University Hospital of Nancy, France, Nancy, France

    Background/Purpose: Women with spondyloarthritis (SpA) are often affected by the disease during their reproductive years1. However, little is known about the impact of the disease…
  • Abstract Number: 0182 • ACR Convergence 2020

    Chronic Kidney Disease Is Underestimated in Patients with Rheumatoid Arthritis – Real World Data Gathered from a Network of Rheumatologists

    Stefan Kleinert1, Peter Bartz-Bazzanella2, Cay von der Decken3, Kirsten Karberg4, Florian Schuch5, Georg Gauler6, Patrick Wurth7, Susanna Spaethling-Mestekemper8, Christoph Kuhn9, Matthias Englbrecht10, Wolfgang Vorbrueggen11 and Martin Welcker12, 1Rheumatology-Nephrology Practice, Erlangen, Germany, 2Department of Rheumatology, Internal Medicine, Rhein-Maas-Hospital, Wuerselen, Germany, 3Medical Centre Stolberg, Stolberg, Germany, 4Practice for Rheumatology and Internal Medicine, Berlin, Germany, 5Rheumatology-Nephrology Practice, Erlangen, 6Rheumatology Practice, Osnabrueck, 7Rheumatology Practice, Osnabrueck, Germany, 8Rheumatology Group Practice, Muenchen, Germany, 9Rheumatology Practice, Karlsruhe, 10Freelance Healthcare Data Scientist, Eckental, Germany, 11Foundation for fostering rheumatology, Wuerselen, Germany, 12MVZ für Rheumatologie Dr. M. Welcker, Planegg, Germany

    Background/Purpose: Patient registries have become a common approach to learn from patient-related data by prospectively including large numbers of individuals into a sample followed over…
  • Abstract Number: 0320 • ACR Convergence 2020

    Assessment of Implementation of Treat to Target Concept Using Validated Composite Scores in Psoriatic Arthritis Patients

    Tal Gazitt1, Muhanad Abu Elhija1, Amir Haddad1, Idit Lavi1, Muna Elias1 and Devy Zisman1, 1Carmel Hospital, Haifa, Israel

    Background/Purpose: To assess the implementation of the “Treat-to-Target” (T2T) concept using validated composite disease activity scores in daily management of psoriatic arthritis (PsA).Methods: A retrospective…
  • Abstract Number: 0336 • ACR Convergence 2020

    Anxiety and Depression in Psoriatic Arthritis (PsA) – Prevalence and Impact on Patient Reported Outcomes: Real-World Survey in the US and Europe

    Laure Gossec1, Jessica Walsh2, Kaleb Michaud3, Elizabeth Holdsworth4, Steven Peterson5, Sophie Meakin4, Nicola Booth4, Soumya Chakravarty6, James Piercy4 and Alexis Ogdie7, 1Sorbonne Université and Hôpital Universitaire Pitié Salpêtrière, Paris, France, 2University of Utah School of Medicine, George E. Wahlen Veteran Affairs Medical Center, Salt Lake City, UT, 3University of Nebraska Medical Center, Omaha, NE, 4Adelphi Real World, Bollington, United Kingdom, 5Janssen Immunology Global Commercial Strategy Organization, Horsham, PA, 6Janssen Scientific Affairs, LLC, Horsham, PA, USA and Drexel University College of Medicine, Horsham, PA, 7Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA

    Background/Purpose: Anxiety and depression are comorbidities among PsA patients. The impact of anxiety and depression on outcomes in PsA patients has not been characterized in…
  • Abstract Number: 0359 • ACR Convergence 2020

    Clinical Characteristics of Psoriatic Arthritis Patients with Physician-Identified Spondylitis, According to HLA-B27 Status: An Analysis from the Corrona Psoriatic Arthritis/Spondyloarthritis Registry

    Philip Mease1, Soumya Chakravarty2, Robert McLean3, Taylor Blachley3, Toana Kawashima4, Iris Lin5, Jonathan Uy6, Arthur Kavanaugh7 and Alexis Ogdie8, 1Seattle Rheumatology Associates, P.L.L.C., Seattle, WA, 2Janssen Scientific Affairs, LLC, Horsham, PA, USA and Drexel University College of Medicine, Horsham, PA, 3Corrona, LLC, Waltham, MA, 4Corrona, LLC, Waltham, 5Janssen Immunology Global Commercial Strategy Organization, Horsham, 6Janssen Scientific Affairs, LLC, Horsham, 7UC San Diego Health System, San Diego, CA, 8Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA

    Background/Purpose: Axial disease in psoriatic arthritis (PsA) has been reported to occur in anywhere from 25% to 75% of PsA patients (pts). It can be…
  • Abstract Number: 0500 • ACR Convergence 2020

    Genomic, Phenomic, Proteomic Predictors of Psoriatic Arthritis

    Jessica Walsh1, Sophie Belman2, Courtney Carroll2, Michael Milliken2, Benjamin Haaland2, Kristina Callis Duffin2, Gerald Krueger2 and Bing-jian Feng2, 1University of Utah School of Medicine, George E. Wahlen Veteran Affairs Medical Center, Salt Lake City, UT, 2University of Utah, Salt Lake City, UT

    Background/Purpose: Delays in diagnosis of psoriatic arthritis (PsA) are common and impair quality of life and function. The study objective was to identify phenotypes, genetic…
  • Abstract Number: 0878 • ACR Convergence 2020

    Absolute Lymphocyte Count Is Negatively Correlated with Atherosclerotic Cardiovascular Disease Risk Score and Red Cell Distribution Width in Psoriatic Arthritis and Increases with TNF-Inhibitor Therapy

    Angela Gupta1, Sofi Damjanovska2, Alyssa Lange3, Brigid Wilson4, Taissa Bej4, Maya Mattar5, David Zidar6 and Donald Anthony7, 1(1) Department of Medicine, VA Medical Center and VA GRECC, Case Western Reserve University, Cleveland OH, Cleveland, 2(1) Department of Medicine, VA Medical Center and VA GRECC, Case Western Reserve University, Cleveland OH, Cleveland, OH, 3Case Western Reserve University, Cleveland, 4Department of Medicine, VA Medical Center and VA GRECC, Case Western Reserve University, Cleveland OH, Cleveland, 5Department of Medicine, VA Medical Center and VA GRECC, Case Western Reserve University, Cleveland OH, Cleveland, OH, 6Case Western Reserve University/Cleveland VA Medical Center, Cleveland, 7Case Western Reserve University/Cleveland VA Medical Center/MetroHealth Medical Center, Cleveland, OH

    Background/Purpose: Absolute lymphocyte count (ALC) is a parameter that represents the number of lymphocytes (B, T, and NK cells) in the blood, and lymphopenia often…
  • Abstract Number: 0910 • ACR Convergence 2020

    Effect of Filgotinib on the Complete Resolution of Enthesitis in Psoriatic Arthritis (PsA) Patients: 52-week Results from EQUATOR2

    Philip Mease1, Laura Coates2, Filip Van den Bosch3, Philip Helliwell4, Dafna Gladman5, Leen Gilles6, Lien Gheyle6, Mona Trivedi7, Muhsen Alani8 and Robin Besuyen9, 1Seattle Rheumatology Associates, P.L.L.C., Seattle, WA, 2University of Oxford, Oxford, United Kingdom, 3Ghent University Hospital, Ghent, Belgium, 4Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, 5Krembil Research Institute, Toronto Western Hospital, Toronto, ON, Canada, 6Galapagos NV, Mechelen, Belgium, 7Gilead Sciences, Inc., Foster City, CA, 8Gilead Sciences, Inc. and University of Washington, Foster City, CA, 9Galapagos BV, Leiden, Netherlands

    Background/Purpose: EQUATOR (NCT03101670) was a 16-week, Phase 2, double-blind, randomized placebo-controlled trial of filgotinib for PsA. At Week 16, placebo-treated patients could switch to filgotinib…
  • Abstract Number: 1337 • ACR Convergence 2020

    Relationship of the Pro12Ala Polymorphism of the PPARg Gene with Inflammatory Activity, Osteoporosis and Obesity in Patients with Psoriatic Arthritis

    Olga Compán1, Maria Elisa Acosta2, Sonia Pastor2, Guadalupe Manzano Canabal2, Luis Gomez-Lechon Quiros3, Cristina Hidalgo Calleja4, Noelia Cubino2, Ricardo Usategui5, Rogelio Gonzalez Sarmiento5, Olga Martinez Gonzalez6, Ana Isabel Turrión2, Javier Del Pino-Montes2 and Carlos Montilla Morales2, 1Hospital Universitario de Salamanca, ´Salamanca, Spain, 2Hospital Universitario de Salamanca, Salamanca, Spain, 3Complejo Asistencial Universitario de Salamanca, Salamanca, Spain, 4Hospital Universitario Salamanca, Salamanca, Spain, 5Instituto de Investigación Biomédica de Salamanca, Salamanca, Spain, 6Hospital Universitario de Salamanca, Zamora, Spain

    Background/Purpose: In the pathogenesis of psoriatic arthritis (PsA), increased inflammatory cytokines lead to increased RANGO-L activity and stimulation of osteoclasts, leading to osteoporosis. This comorbidity,…
  • Abstract Number: 1369 • ACR Convergence 2020

    Efficacy of Tildrakizumab in PsA: DAPSA Remission and Low Disease Activity in PASDAS Through Week 52

    Saima Chohan1, Arthur Kavanaugh2, Vibeke Strand3, Richard Chou4, Alan Mendelsohn5, Stephen Rozzo5 and Philip Mease6, 1Arizona Arthritis and Rheumatology Research, PLLC, Pheonix, AZ, 2UC San Diego Health System, San Diego, CA, 3Division of Immunology/Rheumatology, Stanford University, Palo Alto, CA, 4University at Buffalo, School of Medicine and Biomedical Sciences, Amherst, NY, 5Sun Pharmaceutical Industries, Inc., Princeton, NJ, 6Seattle Rheumatology Associates, P.L.L.C., Seattle, WA

    Background/Purpose: Tildrakizumab (TIL), an anti–interleukin-23p19 monoclonal antibody, is approved in the US, EU, and Australia for treatment of moderate to severe plaque psoriasis. A randomized,…
  • Abstract Number: 1780 • ACR Convergence 2020

    Maternal and Fetal Outcomes in Pregnant Women with Psoriatic Arthritis: A Systematic Literature Review

    Agna Neto1, Rita Pinheiro Torres2, Helena Donato3, Ana Filipa Mourão2, Jaime Branco2 and Fernando Pimentel-Santos4, 11. Rheumatology Department, Hospital Central do Funchal, Madeira, Portugal. 2. Hospital de Egas Moniz, CHLO, Lisbon, Portugal. 3. CEDOC, NOVA Medical School, Lisbon, Portugal, Lisbon, Portugal, 22. Hospital de Egas Moniz, CHLO, Lisbon, Portugal. 3. CEDOC, NOVA Medical School, Lisbon, Portugal, Lisbon, Portugal, 34. Serviço de Documentação, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal, Coimbra, Portugal, 43.CEDOC, NOVA Medical School, Faculdade de Ciências Médicas da Universidade NOVA de Lisboa, Lisboa, Portugal; 7.Hospital Egas Moniz (CHLO) (Rheumatology Department), Lisboa, Portugal, Lisbon, Portugal

    Background/Purpose: The onset of psoriatic arthritis (PsA) often occurs between the ages of 30 and 50 years. Accordingly, many female patients are diagnosed during childbearing…
  • Abstract Number: 0305 • ACR Convergence 2020

    A Delphi Consensus Study to Standardize Terminology for the Pre-clinical Phase of Psoriatic Arthritis

    Rebecca Haberman1, Lourdes Perez-Chada2, Vinod Chandran3, Cheryl Rosen4, Christopher Ritchlin5, Lihi Eder6, Philip Mease7, Soumya Reddy8, Alexis Ogdie9, Joseph Merola10 and Jose Scher1, 1NYU School of Medicine, New York City, 2Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 3Krembil Research Institute, Toronto Western Hospital, Toronto, ON, Canada, 4University of Toronto, Toronto, ON, Canada, 5Department of Medicine, University of Rochester Medical Center, Rochester, NY, 6Women’s College Research Institute, University of Toronto, Toronto, ON, Canada, 7Seattle Rheumatology Associates, P.L.L.C., Seattle, WA, 8NYU School of Medicine, New York, NY, 9University of Pennsylvania, Philadelphia, PA, 10Brigham and Women’s Hospital, Harvard Medical School, Boston, MA

    Background/Purpose: The concept of prevention of psoriatic arthritis (PsA) has gained increased interest given the physical limitation and poor quality-of-life experienced by PsA patients coupled…
  • Abstract Number: 0321 • ACR Convergence 2020

    Outcome Measures in Psoriatic Arthritis Registries Are Very Heterogeneous: A Systematic Literature Review of 27 Registries, or 16183 Patients

    Krystel Aouad1, Georgia Moysidou1, Antsa Rakotozafiarison1, Bruno Fautrel2 and Laure Gossec1, 1Sorbonne University, INSERM; Pitié-Salpêtrière Hospital, Paris, Ile-de-France, France, 2Sorbonne University, INSERM, IPLES; Pitié-Salpêtrière Hospital, Paris, Ile-de-France, France

    Background/Purpose: Psoriatic arthritis (PsA) is a multidimensional inflammatory disease for which multiple outcome measures can be used, to assess disease activity e.g. through composite scores,…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. Academic institutions, private organizations and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part a scientific presentation or presentation of additional new information that will be available at the time of the meeting) is under embargo until Saturday, November 11, 2023.

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