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Abstracts tagged "Psoriatic arthritis"

  • Abstract Number: 1459 • ACR Convergence 2025

    Fungal Infections, Including Candida, in Patients With Active Psoriatic Arthritis (PsA) Treated With Secukinumab: A Pooled Analysis of 9 Phase 3 Trials

    Shikha Singla1, Linda Grinnell-Merrick2, Weibin Bao3, Artem Zharkov4 and Abhijeet Danve5, 1Medical College of Wisconsin, Milwaukee, WI, 2Novartis Pharmaceuticals Corporation, East Hanover, NJ, 3Novartis Pharmaceuticals Corporation, Hanover, NJ, 4Novartis Pharma AG, Basel, Switzerland, 5Section of Rheumatology, Department of Medicine, Yale School of Medicine, New Haven, CT

    Background/Purpose: PsA is a chronic inflammatory disease characterized by joint pain, swelling and stiffness, and is often accompanied by cutaneous changes linked to psoriasis. Patients…
  • Abstract Number: 1426 • ACR Convergence 2025

    Understanding the Drivers of BASDAI and Back Pain Scores in Psoriatic Arthritis

    Pankti Mehta1, Fadi Kharouf2, Virginia Carrizo Abarza3, Shangyi Gao4, Dafna D. Gladman5, Vinod Chandran6 and Denis Poddubnyy7, 1University of Toronto, Gladman Krembil Psoriatic Arthritis Research Program, Toronto, ON, Canada, 2University Health Network and University of Toronto, Toronto, ON, Canada, Toronto, ON, Canada, 3University of Toronto, Toronto, 4Gladman-Krembil Psoriatic Arthritis Research Program, Centre for Prognosis Studies in the Rheumatic Diseases, Schroeder Arthritis Institute, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada, Toronto, ON, Canada, 5Schroeder Arthritis Institute, Krembil Research Institute, Toronto Western Hospital, Division of Rheumatology, Toronto, ON, Canada, 6University of Toronto, Toronto, ON, Canada, 7Division of Rheumatology, Department of Medicine, University Health Network and University of Toronto, Toronto, Ontario, Canada, and Department of Gastroenterology, Infectious Diseases and Rheumatology, Charité – Universitätsmedizin Berlin, Berlin, Germany; Department of Epidemiology, German Rheumatism Research Centre, Berlin, Germany

    Background/Purpose: The Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) is the most commonly used tool to assess axial disease in psoriatic arthritis (PsA). However, five…
  • Abstract Number: 1095 • ACR Convergence 2025

    Tolerance of non-TNF α treatments in patient with an inflammatory rheumatic (IRD) and autoimmune demyelinating diseases: French retrospective cases series

    dellal azeddine1, Jean-Guillaume Letarouilly2, Jacques Morel3, René-Marc Flipo4, Valerie Devauchelle5, richette pascal6, Philippe Dieude7, Hubert Marotte8, FELTEN Renaud9, LATOURTE Augustin10, CHEVET Baptiste11, HILLIQUIN Pascal12, SORDET Christelle9, DERNIS mmanuelle13, WENDLING Daniel14, Arsène Mekinian15, Nathalie BALLANDRAUD16, Christophe Richez17, TOURNADRE Anne18, salmon Jean -Hugues19, SAILLOT Carine20, kedra joanna21, nahon stephane22, LE GOFF Benoit23, Bruno Fautrel24, Francis BERENBAUM25, David SAADOUN26, PHAM Thao16 and SELLAM JEREMIE27, 1GHI LE RAINCY MONTFERMEIL, Montfermeil, France, 2Université de Lille, CHU Lille, Service de rhumatologie, Lille, France, LILLE, Nord-Pas-de-Calais, France, 3CHU and University of Montpellier, Montpellier, France, 4Université de Lille, CHU Lille, Service de rhumatologie, Lille, France, Lille, France, 5UBO, Brest, France, 6Rheumatology Department, Lariboisiere Hospital, Paris, Ile-de-France, France, 7Service de Rhumatologie, Hôpital Bichat APHP, Paris, Paris, Ile-de-France, France, 8INSERM 1059/University of Saint-Etienne, Saint-Etienne, France, 9Service de Rhumatologie, Centre de référence des maladies auto-immunes rares (RESO), Hôpitaux Universitaires de Strasbourg, Strasbourg, Strasbourg, Alsace, France, 10Rheumatology Department, Lariboisiere Hospital, Paris, France, 11CHU BREST, brest, Bretagne, France, 12CH SUD FRANCILIEN, PARIS, France, 13chu caen, CAEN, Haute-Normandie, France, 14CHU de Besançon, Besançon, Franche-Comte, France, 15Department of Internal Medicine, Inflammation-Immunopathology-Biotherapy Department (DMU i3), Saint-Antoine University Hospital, 75012 Paris, France, Paris, France, 16CHU MARSEILLE, marseille, Provence-Alpes-Cote d'Azur, France, 17Bordeaux University Hospital, Bordeaux, France, 18CHU CLERMONT, CLERMONT, Lorraine, France, 19CHU REIMS, REIMS, Champagne-Ardenne, France, 20CHU ORLEANS, ORLEANS, Pays de la Loire, France, 21Pitié-Salpêtrière Hospital, Rheumatology Department, APHP, Sorbonne University,, Paris, France, 22GHI LE RAINCY MONTFERMEIL, Montfermeil, Ile-de-France, France, 23CHU Nantes, Nantes, France, 24Sorbonne Université - APHP, Department of Rheumatology, Hôpital Pitié-Salpêtrière, Inserm UMRS 1136-5, PARIS, France, Paris, France, 25Sorbonne University/Inserm/AP-HP/4Moving Biotech, Paris, France, 26CHU LA PITIE SALPETRIERE, PARIS, Ile-de-France, France, 27Sorbonne Université, Inserm, Centre de Recherche Saint-Antoine, CRSA, F-75012 Paris, France, /Rheumatology Department, AP-HP Saint-Antoine Hospital, 184, rue du Faubourg Saint-Antoine, 75012, Paris, France., Paris, France

    Background/Purpose: The use of TNFα antagonist is not recommended if the patient have a suspicion or demyelinating diseases (DD) confirmed [1]. There are a few…
  • Abstract Number: 0567 • ACR Convergence 2025

    Sonelokimab in Biologic-Experienced Patients With Active Psoriatic Arthritis: Results From a Phase 2 Trial (ARGO) and Study Design of a Phase 3 Trial (IZAR-2) in Patients With Inadequate Response or Intolerance to Biologic TNFi, Including a Risankizumab Reference Arm

    Atul Deodhar1, Laure Gossec2, Philip J. Mease3, Xenofon Baraliakos4, Lihi Eder5, Alan Kivitz6, Helena Marzo-Ortega7, Frank Behrens8, Ana-Maria Orbai9, Georg Schett10, Arthur Kavanaugh11, Dennis McGonagle12, Christopher Ritchlin13, Nuala Brennan14, Ben Porter-Brown14, Eva Cullen14, Matthew R. Thomas14, Marius Albulescu14, Alex Godwood14, Kristian Reich15 and Laura Coates16, 1Division of Arthritis and Rheumatic Diseases, Oregon Health & Science University, Portland, OR, 2Sorbonne Universite and Pitie-Salpetriere Hospital, Paris, France, 3Department of Rheumatology, Providence-Swedish Medical Center and University of Washington, Seattle, WA, 4Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany, 5University of Toronto, Toronto, ON, Canada, 6Altoona Center for Clinical Research, Duncansville, PA, 7NIHR Leeds Biomedical Research Centre, The Leeds Teaching Hospitals NHS Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine (LIRMM), University of Leeds, Leeds, United Kingdom, 8Rheumatology, Immunology - Inflammation Medicine, University Hospital Goethe-University & Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Frankfurt am Main, Germany, 9Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, 10Uniklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany, Erlangen, Germany, 11University of California, San Diego, School of Medicine, San Diego, CA, 12Leeds Institute of Rheumatic and Musculoskeletal Medicine (LIRMM), University of Leeds, Leeds, United Kingdom, 13University of Rochester Medical Center, Canandaigua, NY, 14MoonLake Immunotherapeutics AG, Zug, Switzerland, 15MoonLake Immunotherapeutics AG and Translational Research in Inflammatory Skin Diseases, Institute for Health Services Research in Dermatology and Nursing, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, Zug, Switzerland, 16Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, England, United Kingdom

    Background/Purpose: Sonelokimab (SLK), a novel Nanobody that binds to both IL-17A and IL-17F with similarly high affinity, is designed to target difficult-to-reach sites of inflammation.…
  • Abstract Number: 0549 • ACR Convergence 2025

    High Prevalence of Obstructive Sleep Apnea in Psoriatic Arthritis: A Polysomnography-Based Cross-Sectional Study

    Suzan Attar1, Siraj Walli2, Yasser Bawazir3, Mohammad Mustafa4, Ayah Boudal5, Faris alhejailli2, Ahmad Bamagoos2 and Omar Kanbr2, 1King Abdulaziz University, Saudi Arabia, Jeddah, Saudi Arabia, 2KAU, Jeddah, Saudi Arabia, 3King Abdulaziz University, Jeddah, Saudi Arabia, 4Jeddah University, Jeddah, Saudi Arabia, 5King Abdullah Medical Complex, Jeddah, Saudi Arabia

    Background/Purpose: Background: Obstructive sleep apnea (OSA) is increasingly recognized in patients with psoriatic arthritis (PsA), yet few studies have used polysomnography (PSG)—the gold-standard diagnostic method.…
  • Abstract Number: 0405 • ACR Convergence 2025

    Juvenile Psoriatic Arthritis and Enthesitis-Related Arthritis: 4-Year Results From the JUNIPERA Extension Study

    Hermine Brunner1, Ivan Foeldvari2, Gerd Horneff3, Antonio Mera Varela4, Angelo Ravelli5, Sharonjeet Kaur6, Swapnil Suhas Dahale7, Ruvie Martin8, Daniel Lovell1, Alberto Martini9 and Nicolino Ruperto10, 1Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2Hamburger Zentrum fuer Kinder und Jugendrheumatologie, Rheumatology, Hamburg, Germany, 3Asklepios Klinik, Hamburg, Germany, 4Rheumatology Division. Hospital Clínico Universitario de Santiago and Instituto de Investigaciones Sanitarias (IDIS), School of Medicine, Santiago de Compostela, Spain, 5IRCCS Istituto Giannina Gaslini, Genoa, Italy, Genoa, Genoa, Italy, 6Novartis Pharma AG, Basel, Switzerland, 7IQVIA, Mumbai, India, 8Novartis Pharmaceuticals Corporation, East Hanover, NJ, 9Università di Genova, Genova, Italy, 10Université Milano Bicocca and Fondazione IRCSS S. Gerardo dei Tintori, Monza, Monza and Brianza, Italy

    Background/Purpose: Secukinumab demonstrated efficacy and safety in patients with juvenile idiopathic arthritis (JIA), including enthesitis-related arthritis (ERA) and juvenile psoriatic arthritis (JPsA), for up to…
  • Abstract Number: 0583 • ACR Convergence 2025

    Baseline Peripheral Phenotypes Are Associated with Differential Response to TNF Inhibitors in Psoriatic Arthritis. A Cluster Analysis Approach

    Raquel Granados1, Jesús Eduardo Martín Salazar2, María Ángeles Puche-Larrubia3, Pedro Ortiz Buitrago4, María Dolores López-Montilla5, Jerusalén Calvo6, Rafaela Ortega-Castro7, Montserrat Romero-Gómez8, Alejandro Escudero-Contreras9, Nuria Barbarroja10 and Clementina López Medina11, 1Hospital Universitario Reina Sofia, Cordoba, Andalucia, Spain, 2Maimonides Institute for Research in Biomedicine of Cordoba (IMIBIC)/ University of Cordoba/ Reina Sofia University Hospital, Rheumatology service/Department of Medical and Surgical Sciences, Cordoba, Spain, Cordoba, Andalucia, Spain, 3Reina Sofia University Hospital, Granada, Spain, 4Maimonides Institute of Biomedical Research of Córdoba (IMIBIC), Cordoba, Andalucia, Spain, 5Rheumatology Department, Reina Sofía University Hospital, Cordoba/IMIBIC/University of Cordoba., CORDOBA, Spain, 6IMIBIC / Reina Sofia Hospital / University of Cordoba, Córdoba, Spain, 7Rheumatology service/Maimonides Institute for Research in Biomedicine of Cordoba (IMIBIC)/ Reina Sofia University Hospital/ University of Cordoba, Spain, Cordoba, Andalucia, Spain, 8Reina Sofia University Hospital, Cordoba, Andalucia, Spain, 9Reina Sofia University Hospital/Maimonides Institute of Biomedical Research of Córdoba(IMIBIC)/University of Cordoba, Cordoba, Andalucia, Spain, 10Rheumatology service/Maimonides Institute for Research in Biomedicine of Cordoba (IMIBIC)/ Reina Sofia University Hospital/ University of Cordoba, Spain/CobiomicBioscience S.l, Cordoba, Spain, Cordoba, Spain, 11Department of Medicine, Hospital Universitario Reina Sofia, University of Cordoba, IMIBIC, Cordoba, Spain

    Background/Purpose: Previous studies have identified subgroups of patients with psoriatic arthritis (PsA) based on the severity of the disease [1,2]. However, no analysis to date…
  • Abstract Number: 0225 • ACR Convergence 2024

    Prediction of Response to Therapies and Flares Based on Ultrasound Findings at Baseline in Psoriatic Arthritis: An Analysis on a Joint Level

    Ummugulsum Gazel1, Seyyid Bilal Acikgoz2, Ricardo Sabido-Sauri1, Ozun Bayindir Tsechelidis3, Sylvia Sangwa4, Elliot Hepworth1 and Sibel Aydin5, 1University of Ottawa, Ottawa, ON, Canada, 2University of Ottawa, Rheumatology, Ottawa, ON, Canada, 3Ottawa University, Ottawa, ON, Canada, 4The Ottawa Hospital Research Institute, Ottawa, Canada, 5University of Ottawa - Ottawa, Ottawa, ON, Canada

    Background/Purpose: It is not clear how to interpret when the ultrasound and physical examination do not agree on a joint level. In this study, we…
  • Abstract Number: 0587 • ACR Convergence 2024

    Achieving Stringent Disease Control Criteria Was Associated with Greater Work Productivity Improvements in Patients with Active Psoriatic Arthritis: Results from Two Phase 3 Studies of Bimekizumab

    William Tillett1, Dafna Gladman2, Laure Gossec3, Jason Eells4, Patrick Healy5, Barbara Ink4, Nikos Lyris4 and Jessica A Walsh6, 1Royal National Hospital of Rheumatic Diseases; Department of Life Sciences, Centre for Therapeutic Innovation, University of Bath, Bath, United Kingdom, 2University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 3Sorbonne Université, Paris, France, 4UCB Pharma, Slough, United Kingdom, 5UCB Pharma, Morrisville, NC, 6Division of Rheumatology, Salt Lake City Veterans Affairs Health and University of Utah Health, Salt Lake City, UT

    Background/Purpose: Psoriatic arthritis (PsA) negatively impacts patients’ physical health and functional ability, which can contribute to reduced work productivity.1,2 We examined the association between achieving…
  • Abstract Number: 0928 • ACR Convergence 2024

    In Vitro Study of Fibroblast-Like Synoviocytes and Macrophages-Like Synoviocytes Isolated from Rheumatoid Arthritis, Psoriatic Arthritis Patients and Healthy Subjects

    monia Maccaferri1, Francesco Zambianchi2, Carlo Salvarani3 and Elisa Pignatti3, 1Azienda Ospedaliero Universitaria di Modena, Modena, Italy, 2Department of Maternal, Child and Adult Medical and Surgical Sciences, University of Modena and Reggio Emilia, Modena, Italy, 3Department of Surgery, Medicine Dentistry and Morphological Sciences with Interest in Transplant, Oncological and Regenerative Medicine, University of Modena and Reggio Emilia, Modena, Italy

    Background/Purpose: Interactions between fibroblast-like synoviocytes (FLSs) and macrophage-like synoviocytes (MLSs) are pivotal in the pathogenesis of RA and PsA. FLSs both activate and are activated…
  • Abstract Number: 1296 • ACR Convergence 2024

    Effectiveness of Inflammatory Arthritides Educational Modules and Potential for Improved Referral Times

    Christine Kim1, Vincent Vertalino2, Karen Kruzer3 and Allen Anandarajah4, 1University of Rochester, Rochester, 2University of Rochester, Hamburg, NY, 3University of Rochester, Victor, NY, 4University of Rochester Medical Center, Rochester, NY

    Background/Purpose: Early diagnosis and treatment of inflammatory arthritides [rheumatoid arthritis (RA), psoriatic arthritis (PsA) and ankylosing spondylitis (AS)] are associated with improved patient outcomes. However,…
  • Abstract Number: 1466 • ACR Convergence 2024

    Apremilast Treatment in Early Oligoarticular Psoriatic Arthritis Improves Clinical and Patient-Reported Outcomes for up to 48 Weeks – Data from a Phase 4 Trial

    Laure Gossec1, Laura Coates2, Dafna Gladman3, Alexis Ogdie4, Alvin F. Wells5, Joseph Merola6, Paolo Gisondi7, andreas pinter8, Mitsumasa Kishimoto9, Jyotsna Reddy10, Hamid Amouzadeh10, Rebecca Wang10, Shauna Jardon10, Michele Brunori10 and Philip Mease11, 1Sorbonne Université, Paris, France, 2University of Oxford, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Oxford, United Kingdom, 3University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 4Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 5Rheumatology and Immunotherapy Center, Franklin, WI, 6UT Southwestern Medical Center, Newton, MA, 7Dermatology and Venereology, Department of Medicine, Università di Verona, Verona, Italy, 8University Hospital of the Goethe University, Frankfurt am Main, Frankfurt, Germany, 9Department of Nephrology and Rheumatology, Kyorin University School of Medicine, Tokyo, Japan, 10Amgen Inc., Thousand Oaks, CA, 11Swedish Medical Center/Providence St. Joseph Health; University of Washington School of Medicine, Seattle, WA

    Background/Purpose: Most clinical trials of Psoriatic Arthritis (PsA) exclude patients with early oligoarticular (oligo) disease and there is limited evidence to drive treatment decisions in…
  • Abstract Number: 1902 • ACR Convergence 2024

    Ixekizumab for the Treatment of Patients with Spondyloarthritis – Real-world Evidence from the Nationwide Danish Registry, DANBIO

    Kasper Yde Jensen1, Merete Hetland2 and Bente Glintborg3, 1Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark, 2DANBIO and Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Centre of Head and Orthopedics, Rigshospitalet and University of Copenhagen, Copenhagen, Denmark, Glostrup, Denmark, 3DANBIO, Rigshospitalet Glostrup and University of Copenhagen, Virum, Denmark

    Background/Purpose: Clinical trials have provided robust evidence of the efficacy of ixekizumab, an IL-17 inhibitor, in improving the signs and symptoms of psoriatic arthritis (PsA)…
  • Abstract Number: 2315 • ACR Convergence 2024

    Exploring Antibodies in Psoriatic Arthritis: A Novel Autoimmune Biomarker Discovered

    Theo WIRTH1, Emmanuel Massy2, Nathalie Lambert3, Isabelle Auger3, Nathalie Balandraud1 and Florent Amatore4, 1Department of Rheumatology, Sainte Marguerite Hospital, Assistance Publique des Hôpitaux de Marseille, Aix Marseille University, Marseille, France, 2Department of Rheumatology, Lyon Sud Hospital, Hospices Civils de Lyon, Lyon, France, 3INSERM UMRs1097, Arthrites autoimmunes, Marseille, Marseille, France, 4Department of Dermatology, Nord hospital, Assistance Publique des Hôpitaux de Marseille, Aix Marseille University, MARSEILLE 9EME, France

    Background/Purpose: Psoriatic arthritis (PsA) can be challenging to diagnose due to the lack of specific biomarkers. Although a few teams have demonstrated the presence of…
  • Abstract Number: 2332 • ACR Convergence 2024

    PsAID12 Thresholds Defining Disease Impact Severity in Psoriatic Arthritis Developed in an Observational Setting Showed Higher Sensitivity but Lower Specificity Than Those Developed in a Randomized Controlled Trial Setting

    Clementina López Medina1, Ana-Maria Orbai2, Ennio Lubrano3, Laura Coates4, Uta Kiltz5, Ying Ying Leung6, PENELOPE PALOMINOS7, Juan Cañete8, Rossana Scrivo9, Andra Balanescu10, Emmanuelle Dernis11, Sandra Meisalu12, Adeline Ruyssen-Witrand13, MArtin Soubrier14, Sibel Aydin15, Lihi Eder16, Umut Kalyoncu17, Josef Smolen18, Maarten de Wit19 and Laure Gossec20, 1Reina Sofia University Hospital, Cordoba, Spain, 2Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, 3Vincenzo Tiberio Department of Medicine and Health Sciences, University of Molise, Campobasso, Italy, 4University of Oxford, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Oxford, United Kingdom, 5Rheumazentrum Ruhrgebiet Herne, Ruhr-University, D-44649 Herne, Germany, 6Singapore General Hospital, Singapore, Singapore, 7Hospital de Clinicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil, 8Hospital Clinic an IDIBAPS, Barcelona, Spain, 9Sapienza Università di Roma, Rome, Italy, Roma, Italy, 10UNIVERSITY OF MEDICINE AND PHARMACY CAROL DAVILA, Bucharest, Romania, 11CH LE MANS, LE MANS, Pays de la Loire, France, 12Physician, Tallinn, Estonia, 13Toulouse University Hospital, Toulouse, France, 14Gabriel-Montpied Hospital, Clermont-ferrand, France, 15University of Ottawa - Ottawa, Ottawa, ON, Canada, 16University of Toronto, Women’s College Hospital and Department of Medicine, Toronto, ON, Canada, 17Hacettepe University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Ankara, Turkey, 18Medical University of Vienna, Vienna, Austria, 19Stichting Tools, Patient Research Partner, Amsterdam, Netherlands, 20Sorbonne Université, Paris, France

    Background/Purpose: The Psoriatic Arthritis (PsA) Impact of Disease questionnaire (PsAID12) score (range 0-10) allows for the assessment of patient-important symptoms and life impact in PsA.…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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