ACR Meeting Abstracts

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Abstracts tagged "psoriatic arthritis and rheumatoid arthritis (RA)"

  • Abstract Number: 369 • 2019 ACR/ARP Annual Meeting

    Methotrexate and Interstitial Lung Disease in Patients with Inflammatory Articular Disease: A Systematic Review

    Esteban Rubio1, Alejandro Muñoz 1 and Núria Casamira 2, 1Rheumatology Department, University Hospital Virgen del Rocío, Sevilla, Spain, 2Medical Department, Gebro Pharma S.A., Barcelona, Spain

    Background/Purpose: Methotrexate (MTX) is a commonly used drug for inflammatory joint diseases.  Occasionally, its use has been associated with diffuse interstitial lung disease (DILD) development1. A…
  • Abstract Number: 2469 • 2019 ACR/ARP Annual Meeting

    Diversity of Poly-Functional T Cells in Psoriatic Arthritis and Rheumatoid Arthritis and Its Therapeutic Significance

    Siba Raychaudhuri1 and Smritikana Raychaudhuri 2, 1UC Davis School of Medicine, Sacramento, CA, 2UC Davis School of Medicine, Davis, CA

    Background/Purpose: Importance to specific T cell subpopulations has been attributed for specific diseases such as Th17 cells in psoriatic disease, Th1 cells in TB and…
  • Abstract Number: 2476 • 2019 ACR/ARP Annual Meeting

    Side Effects of Methotrexate and TNFi: Differences in Tolerability Among Patients with PsA and RA

    Alexis Ogdie1, Ervant Maksabedian 2, Bradley Stolshek 2, Yomei Shaw 3 and Kaleb Michaud 4, 1University of Pennsylvania, Philadelphia, PA, 2Amgen Inc., Thousand Oaks, CA, 3FORWARD, The National Databank for Rheumatic Diseases, Wichita, KS, 4FORWARD, The National Databank for Rheumatic Diseases and University of Nebraska Medical Center, Wichita, KS

    Background/Purpose: Methotrexate (MTX) is generally well tolerated in rheumatoid arthritis (RA) but little is known about the tolerability of MTX in psoriatic arthritis (PsA).  One…
  • Abstract Number: 366 • 2018 ACR/ARHP Annual Meeting

    Infectious Complications of Immunosuppressive Therapy in Patients with Common Variable Immunodeficiency (CVID) and Inflammatory Arthritis

    Fatima Alduraibi1, Monica Lawrence2, Larry Borish2 and Adam Carlson3, 1Department of Medicine, University of Virginia Health System, charlottesville, VA, 2Department of Medicine, Division of Allergy and Immunology, University of Virginia Health System, Charlottesville, VA, 3Department of Medicine, Division of Rheumatology, University of Virginia Health System, Charlottesville, VA

    Background/Purpose: Common variable immunodeficiency (CVID) is one of the most common symptomatic primary immunodeficiency syndrome with an incidence of ~1 in 25,000 people. CVID is…
  • Abstract Number: 450 • 2018 ACR/ARHP Annual Meeting

    Injection Site Reaction Associated with Subcutaneous Biologic Agents and Methotrexate. Analysis from the Rhumadata® Clinical Database and Registry

    Denis Choquette1, Louis Bessette2, Jacques Brown2, Boulos Haraoui1, Frédéric Massicotte1, Jean-Pierre Pelletier1, Jean-Pierre Raynauld1, Marie-Anaïs Rémillard1, Diane Sauvageau1, Angèle Turcotte2, Édith Villeneuve1 and Louis Coupal1, 1Rheumatology, Institut de Recherche en Rhumatologie de Montréal (IRRM), Montréal, QC, Canada, 2Rheumatology, Centre de l'Ostéoporose et de Rhumatologie de Québec (CORQ), Québec, QC, Canada

    Background/Purpose: Injection Site Reaction (ISRs) are associated with the subcutaneous (SC) route of administration of all biologic agents, and 3% to 15% of patients reports…
  • Abstract Number: 512 • 2018 ACR/ARHP Annual Meeting

    Incidence of First Cardiovascular Event in Spanish Patients with Chronic Inflammatory Rheumatic Diseases: Prospective Data from an Observational Multicentric Study

    Maria Auxiliadora Martin1, Santos Castañeda2, Carlos González-Juanatey3, Fernando Sánchez-Alonso4, María Carmen García-Gómez5, R López-González6, Jesus Babio7, Antonio Juan-Mas8, María P Moreno-Gil9, Olga Sanchez-González10, Montserrat Romera11, Jose A Pinto-Tasende12, Jose A Piqueras13, Dolores Fábregas14, Javier Llorca15 and Miguel Angel González-Gay16, 1Research Unit of Spanish Society of Rheumatology,, Madrid, Spain, 2Hospital Universitario La Princesa, IIS-Princesa, Madrid, Spain, 3Cardiology Division, Hospital Xeral-Calde, Lugo, Spain, 4Unidad de Investigación, Spanish Society of Rheumatology, Madrid, Spain, 5Rheumatology Division, Consorci Sanitari de Terrassa, Terrassa (Barcelona), Spain, 6Rheumatology, Complejo Hospitalario de Zamora. Spain, Zamora, Spain, 7Rhaumatology, H General de Cabueñes, Gijon, Spain, 8Division of Rheumatology, Hospital Son Llatzer, Palma de Mallorca, Spain, Spain, 9Division of Rheumatology, Hospital San Pedro de Alcántara, Cáceres, Spain, 10Division of Rheumatology, Hospital del Sureste, Madrid, Spain, 11Division of Rheumatology, Hospital de Bellvitge, Barcelona, Spain, 12Complejo Hospitalario Universitario de A Coruña, A Coruña, Spain, 13Division of Rheumatology, Hospital Universitario de Guadalajara, Guadalajara, Spain, 14Division of Rheumatology, Hospital de Barbastro, Huesca, Spain, 15Department of Epidemiology and Computational Biology, School of Medicine, University of Cantabria, and CIBER Epidemiología y Salud Pública (CIBERESP), IDIVAL, Santander, Spain, Santander, Spain, 16School of Medicine, University of Cantabria, Santander, Spain, Santander, Spain

    Background/Purpose: To determine the incidence and risk factors implicated in the development of first cardiovascular event (CVE) in patients with chronic inflammatory rheumatic diseases (CIRD)…
  • Abstract Number: 605 • 2018 ACR/ARHP Annual Meeting

    Clinical Outcomes of Golimumab As Second Line TNF Inhibitor Treatment in Patients with Rheumatoid Arthritis (RA), Psoriatic Arthritis (PsA) or Ankylosing Spondylitis (AS) – Subanalysis of a Non-Interventional Study in Germany

    Klaus Krüger1, Gerd R. Burmester2, Siegfried Wassenberg3, Astrid Thiele4 and Matthias H. Thomas5, 1Medical Centre of Rheumatology, Munich, Germany, 2Rheumatology and Clinical Immunology, Charité-University Medicine Berlin, Berlin, Germany, 3Rheumazentrum Ratingen, Ratingen, Germany, 4Krankenhaus St. Josef Wuppertal, Wuppertal, Germany, 5Medical Affairs, MSD Sharp & Dohme GmbH, Bünde, Germany

    Background/Purpose: Golimumab (GLM) has demonstrated efficacy and safety in patients (pts.) with active RA after treatment with at least one TNFi in a RCT. However,…
  • Abstract Number: 1147 • 2018 ACR/ARHP Annual Meeting

    Golimumab Improves Work Productivity and Activity Impairment in Patients with Rheumatoid Arthritis (RA), Ankylosing Spondylitis (AS) and Psoriatic Arthritis (PsA): 1-Year Results from a Non- Interventional Trial in Germany

    Klaus Krüger1, Sven Remstedt2, Astrid Thiele3 and Ines Klaudius4, 1Medical Centre of Rheumatology, Munich, Germany, 2Rheuma Praxis Berlin, Berlin, Germany, 3Krankenhaus St. Josef Wuppertal, Wuppertal, Germany, 4MSD Sharp & Dohme GmbH, Haar, Germany

    Background/Purpose: Non-interventional studies (NIS) are essential instruments in pharmaceutical research not only for pharmaceutical companies but also for regulatory authorities or reimbursement bodies in Germany.…
  • Abstract Number: 1386 • 2018 ACR/ARHP Annual Meeting

    Golimumab Improves Work Productivity and Activity As Well As Quality of Life in Patients with Rheumatoid Arthritis (RA), Psoriasis Arthritis (PsA) and Axial Spondyloarthritis (axSpA): Interim Results from a Non-Interventional Study in Austria (Go Active)

    Christian Dejaco1, Thomas Mueller2, Omid Zamani, MD3, Ulrike Kurtz, MD4, Stefan Egger, MD5, Johannes Resch Passini, MD6, Anna Totzauer, MD7, Wolfgang Eisterer8, Babak Yazdani-Biuki, MD, Univ.Doc.9, Thomas Schwingenschloegl, MD10, Peter Peichl, MD. Univ.Doc. Msc11, Angelika Kraus12, Gerhard Naerr, PhD13 and Verena Rickert, MD. MBA14, 1Rheumatology and Immunology, Medical University Graz, Graz, Austria, 2Private Office Dr. Thomas Mueller, Graz, Austria, 3Rheuma Zentrum Favoriten, Vienna, Austria, 4Rheuma Praxis Dr. Kurtz, Gleisdorf, Austria, 5Ordination Gesundheitsquadrat, Vienna, Austria, 6Rheumatology Department, Rheuma-Zentrum Wien-Oberlaa GmbH, Vienna, Austria, 7Private Office Dr. Anna Totzauer, Gmuend, Austria, 8Department of Hematology and Internal Oncology, KLINIKUM- KLAGENFURT am WÖRTHERSEE, Klagenfurt, Austria, 9Dr. Schrenk & Dr. Yazdani-Biuki OG - Gruppenpraxis, Fuerstenfeld, Austria, 10Private Office Dr. Thomas Schwingenschloegl, Wiener Neudorf, Austria, 11Private Office Prim. Univ. Doz. Dr. Peter Peichl, MSc, Vienna, Austria, 12Private Office, Private Office Angelika Kraus, Melk, Austria, 13Medical Affairs, Merck Sharp & Dohme GmbH, Vienna, Austria, 14Medical Affairs, Merck Sharp&Dohme GmbH, Vienna, Austria

    Background/Purpose: Golimumab has shown clinical efficacy and tolerability within its clinical trial program. No systematic outcome data regarding patient‐reported outcomes and health economic parameters reflecting…
  • Abstract Number: 1392 • 2018 ACR/ARHP Annual Meeting

    Decreased Injection Site Pain Associated with New Etanercept Formulation in Patients with Rheumatoid Arthritis or Psoriatic Arthritis

    Stanley Cohen1, Ahmed Samad2, Elaine Karis2, Bradley S. Stolshek2, Mona Trivedi2, Hao Zhang2, Girish A. Aras2, Greg Kricorian2 and James Chung2, 1Metroplex Clinical Research Center, Dallas, TX, 2Amgen Inc., Thousand Oaks, CA

    Background/Purpose: Injection site pain (ISP) is a component of the patient experience with injectable drugs. A new formulation of etanercept was developed to reduce ISP.…
  • Abstract Number: 1660 • 2018 ACR/ARHP Annual Meeting

    Depression Has a Greater Impact on Psoriatic Arthritis Than Rheumatoid Arthritis

    Surjeet Dheer1, Vivekanand Tiwari2, Ammarah Hussain1, Kakageldi Hommadov1, Ana Maheshwari1 and Martin J. Bergman3, 1Mercy Catholic Medical Center, Philadelphia, PA, 2St John's Hospital, Springfield, IL, 3Drexel University College of Medicine, Philadelphia, PA

    Background/Purpose: Depression has been shown to be more common in patients with psoriatic arthritis (PsA) and rheumatoid arthritis (RA), than in the general population. The…
  • Abstract Number: 1983 • 2018 ACR/ARHP Annual Meeting

    Mutations Associated with Clonal Hematopoiesis of Indeterminate Potential Are Found in Peripheral Blood and Synovial Fluid Macrophages from Patients with Rheumatoid and Psoriatic Arthritis

    Maria De Santis1, Matteo Zampini2, Natasa Isailovic1, Elena Generali1, Giacomo Maria Guidelli1, Matteo Della Porta2 and Carlo Selmi1,3, 1Rheumatology and Clinical Immunology Unit, Humanitas Research Hospital, Rozzano (MI), Italy, 2Oncology and Hematology Unit, Humanitas Research Hospital, Humanitas University, Rozzano (MI), Italy, 3BIOMETRA Department, University of Milan, Milan, Italy

    Background/Purpose: Myeloidmutations commonly associated to neoplasia in patients who do not meet the diagnostic criteria for myelodysplastic syndrome are coined as clonal hematopoiesis of indeterminate…
  • Abstract Number: 2060 • 2018 ACR/ARHP Annual Meeting

    Comparative Histologic and Molecular Analysis of Synovial Tissue in Early Treatment-Naïve Psoriatic and Rheumatoid Arthritis

    Alessandra Nerviani1, Frances Humby1, Gloria Lliso Ribera1, Wang Sin Tan1, Marie Astrid Boutet1, Katriona Goldmann1, Fabiola Bene1, Rebecca Hands1, Stephen Kelly2, Michele Bombardieri3, Myles J. Lewis3, Chris Buckley4, Peter C. Taylor5, Iain B. McInnes6 and Costantino Pitzalis1, 1Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom, 2Rheumatology Department, Barts Health NHS Trust, London, London, United Kingdom, 3Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Queen Mary University of London, London, United Kindgdom, London, United Kingdom, 4Institute of Inflammation and Ageing (IIA), University of Birmingham, Birmingham, United Kingdom, 5University of Oxford Botnar Research Centre, Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Oxford, United Kingdom, 6Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom

    Background/Purpose: Rheumatoid Arthritis (RA) and Psoriatic Arthritis (PsA) are chronic joint conditions characterised by persistent inflammation of the synovial tissue (ST). Previous reports suggested less…
  • Abstract Number: 1583 • 2017 ACR/ARHP Annual Meeting

    Increase in Arginase Activity and Related Arginine Metabolites in Patients with Rheumatoid Arthritis (RA) and Psoriatic Arthritis (PsA): Potential Mechanisms for Endothelial Dysfunction

    M. Elaine Husni1, Vandana Rai2, Marcia Leon Rabanal3 and Unnikrishnan Chandrasekharan4, 1Cleveland Clinic, Cleveland, OH, 2Cellular and Molecular Medicine, Cleveland Clinic Foundation, Cleveland, OH, 3Rheumatology, Cleveland Clinic Foundation, Cleveland, OH, 4Department of Cellular and Molecular Medicine, Cleveland Clinic, Cleveland, OH

    Background/Purpose: A high prevalence of CVD exists among patients with PsA and RA. The cardiovascular morbidity and mortality are hypothesized to be due in part…
  • Abstract Number: 2524 • 2017 ACR/ARHP Annual Meeting

    Weight Change before and after Diagnosis in Patients with Psoriatic Arthritis, Rheumatoid Arthritis, and Ankylosing Spondylitis

    Alexis Ogdie1, Michael D. George2, Joel Gelfand3, Maureen Dubreuil4, Thorvardur Love5 and Joshua Baker6, 1Medicine/Rheumatology and Epidemiology, University of Pennsylvania, Philadelphia, PA, 2Division of Rheumatology, University of Pennsylvania, Philadelphia, PA, 3University of Pennsylvania Health System , Philadelphia, PA, 4Clinical Epidemiology, Boston University School of Medicine, Boston, MA, 5Landspitali University Hospital, Reykjavik, Iceland, 6Rheumatology, University of Pennsylvania, Philadelphia, PA

    Background/Purpose:   Rheumatoid arthritis (RA) has been associated with weight loss around the time of diagnosis; little is known about weight change around diagnosis in…
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