Abstracts tagged "psoriasis"

Abstract Number: 1733 • 2016 ACR/ARHP Annual Meeting
Sustained Efficacy of Ixekizumab in Patients with Moderate-to-Severe Plaque Psoriasis and Concomitant Psoriatic Arthritis
Kim Papp¹, Alice B. Gottlieb², Catherine L. Shuler³, Russel T. Burge³, Gregory Cameron³, Lisa Kerr³ and Philip J Mease⁴, ¹K Papp Clinical Research, Inc. and Probity Medical Research, Waterloo, ON, Canada, ²Tufts University School of Medicine, Boston, MA, ³Eli Lilly and Company, Indianapolis, IN, ⁴Rheumatology Research, Swedish Medical Center and University of Washington, Seattle, WA
Background/Purpose: PsA, a chronic immune-mediated inflammatory disease, can be progressive and destructive, resulting in physical deformities, impaired function, decreased quality of life, and increased mortality.…
Abstract Number: 7L • 2015 ACR/ARHP Annual Meeting
Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA): Treatment Recommendations for Psoriatic Arthritis 2015
Laura C Coates^1,2, Arthur Kavanaugh³, Philip J. Mease⁴, Enrique R. Soriano⁵, M Laura Acosta-Felquer⁶, April W Armstrong⁷, Wilson Bautista-Molano⁸, Wolf-Henning Boehncke⁹, Willemina Campbell¹⁰, Alberto Cauli¹¹, Luis Espinoza¹², Oliver FitzGerald¹³, Dafna D. Gladman¹⁴, Alice B. Gottlieb¹⁵, Philip S. Helliwell², M. Elaine Husni¹⁶, Thorvardur Love^17,18, Ennio Lubrano¹⁹, Neil J McHugh²⁰, Peter Nash²¹, Alexis Ogdie-Beatty²², Ana-Maria Orbai²³, Andrew Parkinson²⁴, Denis O'Sullivan²⁵, Cheryl F Rosen²⁶, Sergio Schwartzman²⁷, Evan Siegel²⁸, Sergio Toloza²⁹, William Tuong³⁰ and Christopher T. Ritchlin³¹, ¹Medicine, University of Rochester, Rochester, NY, ²Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ³University of California San Diego, La Jolla, CA, ⁴Rheumatology Research, Swedish Medical Center, Seattle, WA, ⁵Rheumatology, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁶Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁷Keck School of Medicine, University of Southern California, Los Angeles, CA, ⁸Department of Rheumatology, Faculty of Medicine HMC/UMNG, Bogota, Colombia, Bogotá, Colombia, ⁹Department of Dermatology,, Geneva University Hospital, Geneva, Switzerland, ¹⁰Toronto Western Hospital, Toronto, ON, Canada, ¹¹University of Cagliari, Cagliari, Italy, ¹²Medicine-Section of Rheumatology, LSU Medical Center, New Orleans, LA, ¹³Department of Rheumatology, St. Vincent’s University Hospital, UCD School of Medicine and Medical Sciences and Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland, ¹⁴Division of Rheumatology, Toronto Western Hospital and University of Toronto, Toronto, ON, Canada, ¹⁵Tufts Medical Center, Boston, MA, ¹⁶Rheumatology Dept A50, Cleveland Clinic, Cleveland, OH, ¹⁷Faculty of Medicine, University of Iceland, Reykjavik, Iceland, ¹⁸Landspitali University Hospital, Reykjavík, Iceland, ¹⁹Cattedra di Reumatologia, Università del Molise, Campobasso, Italy, ²⁰Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom, ²¹Department of Medicine, University of Queensland, Brisbane, Australia, ²²Medicine/Rheumatology, Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA, ²³Rheumatology, Johns Hopkins University, Baltimore, MD, ²⁴Chapel Allerton Hospital, Leeds, United Kingdom, ²⁵St. Vincent’s University Hospital, Dublin, Ireland, ²⁶Division of Dermatology, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada, ²⁷Rheumatology, Hospital for Special Surgery, New York, NY, ²⁸Arthritis & Rheumatism Assoc, Wheaton, MD, ²⁹Rheumatology, Ministry of Health, San Fernando del Valle de Catamarca, Argentina, ³⁰Department of Dermatology, University of California David, Davis, CA, ³¹Allergy, Immunology and Rheumatololgy Division, University of Rochester Medical Center, Rochester, NY
Background/Purpose: Since the 2009 GRAPPA treatment recommendations were published, therapeutic options and management strategies for psoriatic arthritis (PsA) have advanced considerably. We updated and improved…
Abstract Number: 566 • 2015 ACR/ARHP Annual Meeting
Genome-Wide Trans-Ancestry Meta-Analysis of Herpes Zoster in RA and Pso Patients Treated with Tofacitinib
Nan Bing¹, HuanYu Zhou¹, BaoHong Zhang¹, John D Bradley², Makoto Nagaoka³, Hernan Valdez⁴, Michael Vincent¹ and James D. Clark¹, ¹Pfizer Inc, Cambridge, MA, ²Pfizer Inc, Groton, CT, ³Pfizer Inc, Tokyo, Japan, ⁴Pfizer Inc, New York, NY
Background/Purpose: Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis (RA). Rates of herpes zoster (HZ) were higher than observed with…
Abstract Number: 3234 • 2015 ACR/ARHP Annual Meeting
Roadblocks Perceived By Canadian Dermatologists for Referring Patients with Suspected Psoriatic Arthritis
Renise Ayearst¹, Daniel Pereira¹, Charles Lynde², Holly Etchegary³ and Vinod Chandran¹, ¹Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ²University of Toronto, Toronto, ON, Canada, ³Memorial University of Newfoundland, St.John's, NF, Canada
Background/Purpose: The current system of referral by Canadian dermatologists of patients who may have psoriatic arthritis (PsA) to rheumatologists is suboptimal. Hypothesizing that knowledge level,…
Abstract Number: 649 • 2015 ACR/ARHP Annual Meeting
Measures of Health-Related Quality of Life in Psoriatic Arthritis: Are They Sensitive to Both Joint and Skin Aspects?
Mwidimi Ndosi¹, Ming-Anne Hsu², J. Cappelleri³, Amit Chhabra⁴, Heather Jones⁵ and Philip S. Helliwell⁶, ¹School of Healthcare, University of Leeds, Leeds, United Kingdom, ²445 Eastern Point Road, Pfizer Inc, Groton, CT, ³Statistics, Pfizer Inc, New London, CT, ⁴Pfizer Inc, Collegeville, PA, ⁵Inflammation Global Medical Affairs, Pfizer, Collegeville, PA, ⁶Section of Musculoskeletal Disease, University of Leeds, Leeds, United Kingdom

Background/Purpose: Psoriatic Arthritis Quality of Life (PsAQol), Ankylosing Spondylitis Quality of Life (ASQoL), and Dermatology Life Quality Index (DLQI) are tools that assess different aspects of health-related…
Abstract Number: 657 • 2015 ACR/ARHP Annual Meeting
Routine Assessment of Patient Index Data 3 Score (RAPID3) and Psoriasis Quality of Life (PQoL-12) Assess Different Domains in Psoriasis (PsO) and Psoriatic Arthritis (PsA) Patients
Kiana Vakil-Gilani¹, Alexis Dinno², Neha Garg³ and Atul A. Deodhar⁴, ¹Arthritis and Rheumatic diseases, Oregon Health and Science University, Portland, OR, ²School of Community Health, Portland State University, Portland, OR, ³Rheumatology, Oregon Health and Science University, Portland, OR, ⁴Division of Arthritis & Rheumatic Diseases, Oregon Health & Science University, Portland, OR
Background/Purpose: PQoL-12 is a validated composite tool (range: 0–120) assessing patients' quality of life in PsO and PsA. RAPID3 is another validated composite index (range:…
Abstract Number: 670 • 2015 ACR/ARHP Annual Meeting
Evaluation of the Predictive Value of Non-Specific Musculoskeletal Symptoms in Preclinical Phases of Psoriatic Arthritis
Lihi Eder¹, Ari Polachek¹, Cheryl Rosen², Vinod Chandran¹, Richard J. Cook³ and Dafna D. Gladman¹, ¹Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ²Dermatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ³Statistics and Actuarial Science, University of Waterloo, Waterloo, ON, Canada
Background/Purpose: Limited information exists about the characteristics of pre-clinical phases of psoriatic arthritis (PsA). We aimed to assess whether the presence and trends in non-specific…
Abstract Number: 688 • 2015 ACR/ARHP Annual Meeting
Clinical Improvements in Psoriasis and Psoriatic Arthritis with Surgical Weight Loss
Monica Sethi¹, Christine Ren-Fielding², Ana Clara Caminer^3,4, Jose U. Scher⁵ and Soumya M. Reddy⁶, ¹Department of Surgery, Division of Bariatric Surgery, New York University School of Medicine, New York, NY, ²Department of Surgery, New York University School of Medicine, New York, NY, ³Rheumatology, Facultad de Ciencias Médicas, Universidad Nacional de Rosario, Rosario, Argentina, ⁴Rheumatology, Sanatorio Parque, Rosario, Argentina, ⁵Department of Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY, ⁶Division of Rheumatology, New York University School of Medicine, New York, NY
Background/Purpose: Obesity is more prevalent among patients with psoriasis and psoriatic arthritis (PsA). This correlation appears to be related to fat tissue-driven systemic inflammation. Although…
Abstract Number: 979 • 2015 ACR/ARHP Annual Meeting
HLA Class I Genes As Susceptibility Markers of Psoriatic Arthritis in Patients with Psoriasis – a Meta-Analysis
Lihi Eder¹, Fatima Abji², Cheryl Rosen³, Muhammad Haroon⁴, Vinod Chandran¹, Rubén Queiro⁵, Shelley Bull⁶, Richard J. Cook⁷, Proton Rahman⁸, Robert Winchester⁹, Oliver FitzGerald¹⁰ and Dafna D. Gladman¹, ¹Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ²University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ³Dermatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ⁴Kerry General Hospital, Tralee, Ireland, ⁵Rheumatology Service, Hospital Universitario Central de Asturias, Oviedo, Spain, ⁶School of Public Health, Mount Sinai Hospital, Toronto, ON, Canada, ⁷Statistics and Actuarial Science, University of Waterloo, Waterloo, ON, Canada, ⁸Computer Sciences, Memorial University of Newfoundland, St. John's, NF, Canada, ⁹Columbia University, New York, NY, ¹⁰Department of Rheumatology, St Vincent's University Hospital, Dublin, Ireland
Background/Purpose: Genes that differentiate patients with psoriatic arthritis (PsA) from those with psoriasis alone may serve as markers for the development of PsA in psoriasis…
Abstract Number: 1202 • 2015 ACR/ARHP Annual Meeting
Knowledge and Perception of Cardiovascular Disease Risk in Patients with Psoriatic Disease
Dennis Wong¹, Daniel Pereira², Sutha Shanmugarajah¹, Renise Ayearst², Dafna Gladman², Cheryl Rosen³ and Vinod Chandran², ¹University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ²Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ³Dermatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada
Background/Purpose: The prevalence of cardiovascular diseases (CVD) is higher in patients with psoriatic disease. Psoriatic disease is known to be an independent risk factor for…
Abstract Number: 1718 • 2015 ACR/ARHP Annual Meeting
Entheseal Abnormalities and Nail Involvement at the Distal Interphalangeal Joints on Ultrasound Examination in Patients with Psoriasis and Psoriatic Arthritis. Could the Nail-Enthesitis Theory be Supported?
M Laura Acosta-Felquer¹, Erika Catay², Leandro Ferreyra-Garrot³, Santiago Ruta¹, David A. Navarta⁴, Javier Rosa⁵, Ricardo Galimberti⁶, Maria L. Galimberti⁶, Ricardo Garcia-Monaco⁷ and Enrique R. Soriano⁸, ¹Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ²Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Instituto Universitario Hospital Italiano de Buenos Aires, and Fundacion PM Catoggio,, Buenos Aires, Argentina, ³Rheumatology Section, Internal Medicine Service, Hospital Italiano de Buenos Aires, Instituto Universitario Hospital Italiano de Buenos Aires, and Fundacion PM Catoggio, Internal Medicine, Argentina, Buenos Aires, Argentina, ⁴Internal Medicine, Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁵Rheumatology, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁶Dermatology Service, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁷Radiology and Imagenology Department, Hospital italiano de Buenos Aires, Buenos Aires, Argentina, ⁸Internal Medicine, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina
Background/Purpose: It has been shown that nail involvement in psoriasis is associated with systemic enthesopathy. The association of enthesopathy and nail disease at distal…
Abstract Number: 1737 • 2015 ACR/ARHP Annual Meeting
Increased Osteoclast Precursors with an Elevated DC-STAMP Expression May Identify Psoriasis Patients at Risk for Psoriatic Arthritis
Yahui Grace Chiu¹, Sutha Shanmugarajah², Dongge Li³, Megan Freiburger⁴, Sharon Moorehead⁵, Dafna Gladman⁶ and Christopher T. Ritchlin⁷, ¹Allergy, Immunology, and Rheumatology, University of Rochester, Rochester, NY, ²Toronto Western Hospital, Toronto, ON, Canada, ³Allergy, Immunology and Rheumatology, University of Rochester, Rochester, NY, ⁴Biology, University of Rochester, Rochester, NY, ⁵Allergy, Immunology & Rheumatology, University of Rochester, Rochester, NY, ⁶Allergy, Immunology & Rheumatology, Toronto Western Hospital, Toronto, ON, Canada, ⁷Allergy, Immunology and Rheumatololgy Division, University of Rochester Medical Center, Rochester, NY
Background/Purpose: Approximately 25% of psoriasis (Ps) patients develop into psoriatic arthritis (PsA) within 10 years. This Ps-to-PsA transition paradigm provides a unique opportunity to recognize…
Abstract Number: 2063 • 2015 ACR/ARHP Annual Meeting
The Survival Impact of Statins in Psoriasis and Psoriatic Arthritis: A General Population-Based Cohort Study
Sian Yik Lim¹, Na Lu² and Hyon K. Choi², ¹Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, ²Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA
Background/Purpose: Given their lipid-lowering and anti-inflammatory properties, statins may have dual cardioprotective and anti-rheumatic benefits in psoriasis or psoriatic arthritis. These effects may confer survival…
Abstract Number: 2065 • 2015 ACR/ARHP Annual Meeting
Verification of Novel Soluble Biomarkers That Differentiate Patients with Psoriatic Arthritis from Those with Psoriasis without Psoriatic Arthritis
Vinod Chandran¹, Daniela Cretu^2,3, Lisa Gao⁴, Kun Liang⁴, Antoninus Soosaipillai³ and Eleftherios Diamandis^2,3,5, ¹Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ²Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada, ³Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, ON, Canada, ⁴Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, ON, Canada, ⁵Department of Clinical Biochemistry, University Health Network, Toronto, ON, Canada
Background/Purpose: There is a high prevalence of undiagnosed psoriatic arthritis (PsA) in psoriasis patients. Therefore identifying soluble biomarkers for PsA will help in screening psoriasis…
Abstract Number: 2806 • 2015 ACR/ARHP Annual Meeting
Bacterial Skin Microbiome in Psoriatic Arthritis Ã¢â‚¬â€œ Pilot Data from Psoriatic Plaques on Dry Skin Sites from Patients with Psoriasis (PsC) and Psoriatic Arthritis (PsA)
Madhura Castelino¹, Stephen Eyre², Mauro Tutino², John Moat³, Paul Martin², Umer Ijaz⁴, Christopher Quince⁵, Pauline Ho¹, Mathew Upton⁶ and Anne Barton^1,7, ¹NIHR Manchester Musculoskeletal Biomedical Research Unit, Manchester Academic Health Science Centre, Manchester, United Kingdom, ²Arthritis Research UK Centre for Genetics and Genomics, University of Manchester, Manchester, United Kingdom, ³Microbiology and Virology Unit, University of Manchester, Manchester, United Kingdom, ⁴School of Engineering, University of Glasgow, Glasgow, United Kingdom, ⁵Warwick Medical School, University of Warwick, Coventry, United Kingdom, ⁶Plymouth University Peninsula Schools of Medicine and Dentistry, Plymouth, United Kingdom, ⁷Arthritis Research UK Centre for Genetics and Genomics, Centre for Musculoskeletal Research, Manchester Academic Health Science Centre, The University Of Manchester, Manchester, United Kingdom
Background/Purpose: In complex traits like psoriasis (PsC) and psoriatic arthritis (PsA) interactions between genetics and environmental factors are thought to result in the development of…

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