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Abstracts tagged "psoriasis"

  • Abstract Number: 1422 • 2016 ACR/ARHP Annual Meeting

    Identifying Generic and Specific Patients’ Perspectives on Disease- and Treatment-Related Issues in Rheumatoid Arthritis, Psoriatic Arthritis, and Psoriasis: A Qualitative Concept Mapping Study

    Tanja Schjødt Jørgensen1, Louise Klokker1, Henrik Gudbergsen2, Simon Francis Thomsen3, Robin Christensen4, Henning Bliddal1 and Lars Erik Kristensen1, 1The Parker Institute, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark, 2The Parker Institute, Copenhagen University Hospital, Bispebjerg and Frederiksberg,, Copenhagen, Denmark, 3Department of Dermatology, Bispebjerg Hospital & Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark, 4Musculoskeletal Statistics Unit, The Parker Institute, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark

    Identifying generic and specific patients’ perspectives on disease- and treatment-related issues in rheumatoid arthritis, psoriatic arthritis, and psoriasis: a qualitative concept mapping studyT.S. Jørgensen1, L.…
  • Abstract Number: 7L • 2015 ACR/ARHP Annual Meeting

    Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA): Treatment Recommendations for Psoriatic Arthritis 2015

    Laura C Coates1,2, Arthur Kavanaugh3, Philip J. Mease4, Enrique R. Soriano5, M Laura Acosta-Felquer6, April W Armstrong7, Wilson Bautista-Molano8, Wolf-Henning Boehncke9, Willemina Campbell10, Alberto Cauli11, Luis Espinoza12, Oliver FitzGerald13, Dafna D. Gladman14, Alice B. Gottlieb15, Philip S. Helliwell2, M. Elaine Husni16, Thorvardur Love17,18, Ennio Lubrano19, Neil J McHugh20, Peter Nash21, Alexis Ogdie-Beatty22, Ana-Maria Orbai23, Andrew Parkinson24, Denis O'Sullivan25, Cheryl F Rosen26, Sergio Schwartzman27, Evan Siegel28, Sergio Toloza29, William Tuong30 and Christopher T. Ritchlin31, 1Medicine, University of Rochester, Rochester, NY, 2Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, 3University of California San Diego, La Jolla, CA, 4Rheumatology Research, Swedish Medical Center, Seattle, WA, 5Rheumatology, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, 6Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, 7Keck School of Medicine, University of Southern California, Los Angeles, CA, 8Department of Rheumatology, Faculty of Medicine HMC/UMNG, Bogota, Colombia, Bogotá, Colombia, 9Department of Dermatology,, Geneva University Hospital, Geneva, Switzerland, 10Toronto Western Hospital, Toronto, ON, Canada, 11University of Cagliari, Cagliari, Italy, 12Medicine-Section of Rheumatology, LSU Medical Center, New Orleans, LA, 13Department of Rheumatology, St. Vincent’s University Hospital, UCD School of Medicine and Medical Sciences and Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland, 14Division of Rheumatology, Toronto Western Hospital and University of Toronto, Toronto, ON, Canada, 15Tufts Medical Center, Boston, MA, 16Rheumatology Dept A50, Cleveland Clinic, Cleveland, OH, 17Faculty of Medicine, University of Iceland, Reykjavik, Iceland, 18Landspitali University Hospital, Reykjavík, Iceland, 19Cattedra di Reumatologia, Università del Molise, Campobasso, Italy, 20Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom, 21Department of Medicine, University of Queensland, Brisbane, Australia, 22Medicine/Rheumatology, Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA, 23Rheumatology, Johns Hopkins University, Baltimore, MD, 24Chapel Allerton Hospital, Leeds, United Kingdom, 25St. Vincent’s University Hospital, Dublin, Ireland, 26Division of Dermatology, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada, 27Rheumatology, Hospital for Special Surgery, New York, NY, 28Arthritis & Rheumatism Assoc, Wheaton, MD, 29Rheumatology, Ministry of Health, San Fernando del Valle de Catamarca, Argentina, 30Department of Dermatology, University of California David, Davis, CA, 31Allergy, Immunology and Rheumatololgy Division, University of Rochester Medical Center, Rochester, NY

    Background/Purpose:  Since the 2009 GRAPPA treatment recommendations were published, therapeutic options and management strategies for psoriatic arthritis (PsA) have advanced considerably. We updated and improved…
  • Abstract Number: 1737 • 2015 ACR/ARHP Annual Meeting

    Increased Osteoclast Precursors with an Elevated DC-STAMP Expression May Identify Psoriasis Patients at Risk for Psoriatic Arthritis

    Yahui Grace Chiu1, Sutha Shanmugarajah2, Dongge Li3, Megan Freiburger4, Sharon Moorehead5, Dafna Gladman6 and Christopher T. Ritchlin7, 1Allergy, Immunology, and Rheumatology, University of Rochester, Rochester, NY, 2Toronto Western Hospital, Toronto, ON, Canada, 3Allergy, Immunology and Rheumatology, University of Rochester, Rochester, NY, 4Biology, University of Rochester, Rochester, NY, 5Allergy, Immunology & Rheumatology, University of Rochester, Rochester, NY, 6Allergy, Immunology & Rheumatology, Toronto Western Hospital, Toronto, ON, Canada, 7Allergy, Immunology and Rheumatololgy Division, University of Rochester Medical Center, Rochester, NY

    Background/Purpose: Approximately 25% of psoriasis (Ps) patients develop into psoriatic arthritis (PsA) within 10 years. This Ps-to-PsA transition paradigm provides a unique opportunity to recognize…
  • Abstract Number: 2063 • 2015 ACR/ARHP Annual Meeting

    The Survival Impact of Statins in Psoriasis and Psoriatic Arthritis: A General Population-Based Cohort Study

    Sian Yik Lim1, Na Lu2 and Hyon K. Choi2, 1Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 2Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA

    Background/Purpose: Given their lipid-lowering and anti-inflammatory properties, statins may have dual cardioprotective and anti-rheumatic benefits in psoriasis or psoriatic arthritis. These effects may confer survival…
  • Abstract Number: 2065 • 2015 ACR/ARHP Annual Meeting

    Verification of Novel Soluble Biomarkers That Differentiate Patients with Psoriatic Arthritis from Those with Psoriasis without Psoriatic Arthritis

    Vinod Chandran1, Daniela Cretu2,3, Lisa Gao4, Kun Liang4, Antoninus Soosaipillai3 and Eleftherios Diamandis2,3,5, 1Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 2Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada, 3Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, ON, Canada, 4Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, ON, Canada, 5Department of Clinical Biochemistry, University Health Network, Toronto, ON, Canada

    Background/Purpose: There is a high prevalence of undiagnosed psoriatic arthritis (PsA) in psoriasis patients. Therefore identifying soluble biomarkers for PsA will help in screening psoriasis…
  • Abstract Number: 2806 • 2015 ACR/ARHP Annual Meeting

    Bacterial Skin Microbiome in Psoriatic Arthritis – Pilot Data from Psoriatic Plaques on Dry Skin Sites from Patients with Psoriasis (PsC) and Psoriatic Arthritis (PsA)

    Madhura Castelino1, Stephen Eyre2, Mauro Tutino2, John Moat3, Paul Martin2, Umer Ijaz4, Christopher Quince5, Pauline Ho1, Mathew Upton6 and Anne Barton1,7, 1NIHR Manchester Musculoskeletal Biomedical Research Unit, Manchester Academic Health Science Centre, Manchester, United Kingdom, 2Arthritis Research UK Centre for Genetics and Genomics, University of Manchester, Manchester, United Kingdom, 3Microbiology and Virology Unit, University of Manchester, Manchester, United Kingdom, 4School of Engineering, University of Glasgow, Glasgow, United Kingdom, 5Warwick Medical School, University of Warwick, Coventry, United Kingdom, 6Plymouth University Peninsula Schools of Medicine and Dentistry, Plymouth, United Kingdom, 7Arthritis Research UK Centre for Genetics and Genomics, Centre for Musculoskeletal Research, Manchester Academic Health Science Centre, The University Of Manchester, Manchester, United Kingdom

    Background/Purpose: In complex traits like psoriasis (PsC) and psoriatic arthritis (PsA) interactions between genetics and environmental factors are thought to result in the development of…
  • Abstract Number: 2886 • 2015 ACR/ARHP Annual Meeting

    Secukinumab Safety and Tolerability in Patients with Active Psoriatic Arthritis and Psoriasis: Results from a Pooled Safety Analysis

    Philip J. Mease1, Iain B. McInnes2, Alice B. Gottlieb3, Albert Widmer4, Luminita Pricop5 and Shephard Mpofu4, 1Rheumatology Research, Swedish Medical Center, Seattle, WA, 2Immunology, Infection and Inflammation, University of Glasgow, Glasgow, United Kingdom, 3Dermatology, Tufts Medical Center, Boston, MA, 4Novartis Pharma AG, Basel, Switzerland, 5Integrated Hospital Care (IHC) Franchise, Novartis Pharmaceuticals Corporation, East Hanover, NJ

    Background/Purpose: Secukinumab, a fully human anti–interleukin-17A monoclonal antibody, has been shown to improve the signs and symptoms of psoriasis and psoriatic arthritis (PsA).1–3 Here, we…
  • Abstract Number: 3118 • 2015 ACR/ARHP Annual Meeting

    Clinical Characteristics and Disease Outcomes in Psoriatic Arthritis Patients By Extent of Body Surface Area Affected By Psoriasis: Results from Corrona Registry

    Philip J. Mease1,2,3,4, Chitra Karki5, Carol J. Etzel5,6, Arthur Kavanaugh7, Christopher T. Ritchlin8, Wendi Malley5, Vivian Herrera9, Jacqueline B. Palmer9 and Jeffrey D. Greenberg5,10, 1Swedish Medical Center and University of Washington School of Medicine, Seattle, WA, 2Seattle Rheumatology Associates, Seattle, WA, 3Rheumatology Research, Swedish Medical Center, Seattle, WA, 4Clinical Professor, University of Washington School of Medicine, Seattle, WA, 5Corrona, LLC, Southborough, MA, 6University of Texas M.D. Anderson Cancer Center, Houston, TX, 7University of California San Diego, La Jolla, CA, 8Allergy, Immunology and Rheumatololgy Division, University of Rochester Medical Center, Rochester, NY, 9Novartis Pharmaceuticals Corporation, East Hanover, NJ, 10NYU School of Medicine, New York, NY

    Background/Purpose: Psoriatic arthritis (PsA) is a type of inflammatory arthritis that is commonly comorbid with the skin condition, psoriasis. A major contributor to the severity…
  • Abstract Number: 3119 • 2015 ACR/ARHP Annual Meeting

    The Risk of Venous Thromboembolism in Psoriatic Arthritis, Psoriasis and Rheumatoid Arthritis

    Alexis Ogdie-Beatty1, Daniel Shin2, Junko Takeshita2, Zelma ChiesaFuxench2 and Joel Gelfand3, 1Medicine/Rheumatology, University of Pennsylvania, Philadelphia, PA, 2University of Pennsylvania, Philadelphia, PA, 3University of Pennsylvania Health System , Philadelphia, PA

    Background/Purpose: Venous thromboembolism (VTE), the combined endpoint of deep venous thrombosis (DVT) and pulmonary embolism (PE), is a common and potentially deadly medical problem with…
  • Abstract Number: 3120 • 2015 ACR/ARHP Annual Meeting

    The Prevalence, Incidence and Management of Hypertension, Diabetes and Hyperlipidemia in Psoriatic Arthritis, Psoriasis and Rheumatoid Arthritis

    Kashif Jafri1, Christie M. Bartels2, Daniel Shin3 and Alexis Ogdie-Beatty4, 1Department of Medicine, University of Pennsylvania, Philadelphia, PA, 2Medicine, Rheumatology, University of Wisconsin School of Medicine and Public Health, Madison, WI, 3University of Pennsylvania, Philadelphia, PA, 4Medicine/Rheumatology, University of Pennsylvania, Philadelphia, PA

    Background/Purpose: Psoriasis, psoriatic arthritis (PsA), and rheumatoid arthritis (RA) are associated with an increased risk for cardiovascular disease (CVD).  While management of traditional CVD risk…
  • Abstract Number: 566 • 2015 ACR/ARHP Annual Meeting

    Genome-Wide Trans-Ancestry Meta-Analysis of Herpes Zoster in RA and Pso Patients Treated with Tofacitinib

    Nan Bing1, HuanYu Zhou1, BaoHong Zhang1, John D Bradley2, Makoto Nagaoka3, Hernan Valdez4, Michael Vincent1 and James D. Clark1, 1Pfizer Inc, Cambridge, MA, 2Pfizer Inc, Groton, CT, 3Pfizer Inc, Tokyo, Japan, 4Pfizer Inc, New York, NY

    Background/Purpose: Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis (RA). Rates of herpes zoster (HZ) were higher than observed with…
  • Abstract Number: 3234 • 2015 ACR/ARHP Annual Meeting

    Roadblocks Perceived By Canadian Dermatologists for Referring Patients with Suspected Psoriatic Arthritis

    Renise Ayearst1, Daniel Pereira1, Charles Lynde2, Holly Etchegary3 and Vinod Chandran1, 1Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 2University of Toronto, Toronto, ON, Canada, 3Memorial University of Newfoundland, St.John's, NF, Canada

    Background/Purpose: The current system of referral by Canadian dermatologists of patients who may have psoriatic arthritis (PsA) to rheumatologists is suboptimal. Hypothesizing that knowledge level,…
  • Abstract Number: 649 • 2015 ACR/ARHP Annual Meeting

    Measures of Health-Related Quality of Life in Psoriatic Arthritis: Are They Sensitive to Both Joint and Skin Aspects?

    Mwidimi Ndosi1, Ming-Anne Hsu2, J. Cappelleri3, Amit Chhabra4, Heather Jones5 and Philip S. Helliwell6, 1School of Healthcare, University of Leeds, Leeds, United Kingdom, 2445 Eastern Point Road, Pfizer Inc, Groton, CT, 3Statistics, Pfizer Inc, New London, CT, 4Pfizer Inc, Collegeville, PA, 5Inflammation Global Medical Affairs, Pfizer, Collegeville, PA, 6Section of Musculoskeletal Disease, University of Leeds, Leeds, United Kingdom

    Background/Purpose: Psoriatic Arthritis Quality of Life (PsAQol), Ankylosing Spondylitis Quality of Life (ASQoL), and Dermatology Life Quality Index (DLQI) are tools that assess different aspects of health-related…
  • Abstract Number: 657 • 2015 ACR/ARHP Annual Meeting

    Routine Assessment of Patient Index Data 3 Score (RAPID3) and Psoriasis Quality of Life (PQoL-12) Assess Different Domains in Psoriasis (PsO) and Psoriatic Arthritis (PsA) Patients

    Kiana Vakil-Gilani1, Alexis Dinno2, Neha Garg3 and Atul A. Deodhar4, 1Arthritis and Rheumatic diseases, Oregon Health and Science University, Portland, OR, 2School of Community Health, Portland State University, Portland, OR, 3Rheumatology, Oregon Health and Science University, Portland, OR, 4Division of Arthritis & Rheumatic Diseases, Oregon Health & Science University, Portland, OR

    Background/Purpose: PQoL-12 is a validated composite tool (range: 0–120) assessing patients' quality of life in PsO and PsA. RAPID3 is another validated composite index (range:…
  • Abstract Number: 670 • 2015 ACR/ARHP Annual Meeting

    Evaluation of the Predictive Value of Non-Specific Musculoskeletal Symptoms in Preclinical Phases of Psoriatic Arthritis

    Lihi Eder1, Ari Polachek1, Cheryl Rosen2, Vinod Chandran1, Richard J. Cook3 and Dafna D. Gladman1, 1Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 2Dermatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 3Statistics and Actuarial Science, University of Waterloo, Waterloo, ON, Canada

    Background/Purpose: Limited information exists about the characteristics of pre-clinical phases of psoriatic arthritis (PsA). We aimed to assess whether the presence and trends in non-specific…
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