ACR Meeting Abstracts

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Abstracts tagged "prognostic factors"

  • Abstract Number: 2554 • ACR Convergence 2023

    Validation of a Flare Risk Index Informed by Select Immune Mediators in Systemic Lupus Erythematosus in a Confirmatory Cohort

    Melissa Munroe1, Derek Blankenship2, Daniele DeFreese2, Adrian Holloway2, Mohan Purushothaman2, Wade DeJager3, Susan Macwana3, Joel Guthridge3, Stan Kamp3, Nancy Redinger3, Teresa Aberle3, Eliza Chakravarty3, Cristina Arriens4, Yanfeng Li5, Hu Zeng5, Stephanie Dezzutti6, Peter Izmirly7, Uma Thanarajasingam5, Diane L. Kamen6, Jill Buyon8, Judith James3 and Eldon Jupe2, 1Oklahoma Medical Research Foundation; Progentec Diagnostics, Inc., Oklahoma City, OK, 2Progentec Diagnostics, Inc., Oklahoma City, OK, 3Oklahoma Medical Research Foundation, Oklahoma City, OK, 4Oklahoma Medical Research Foundation and University of Oklahoma Health Sciences Center, Department of Arthritis & Clinical Immunology, Oklahoma City, OK, 5Mayo Clinic, Rochester, MN, 6Medical University of South Carolina, Charleston, SC, 7New York University School of Medicine, New York, NY, 8NYU Grossman School of Medicine, New York, NY

    Background/Purpose: SLE is marked by immune dysregulation linked to varied clinical disease activity. Using a unique confirmatory cohort of SLE patients, this study seeks to…
  • Abstract Number: 0382 • ACR Convergence 2023

    Heterogeneity Within a “difficult to Treat” Rheumatoid Arthritis Patients Cohort: 36% May Have a More Benign Course and Have Distinct Characteristics at bDMARD or tsDMARD Initiation

    Irini Flouri1, Antonios Bertsias2, Argyro Repa2, Nestor Avgoustidis2, Eleni Kalogiannaki2, Sofia Pitsigavdaki3, George Bertsias4 and Prodromos Sidiropoulos4, 1University of Crete Medical School, Heraklion, Greece, 2Rheumatology, Clinical Immunology and Allergy Department, Medical School, University of Crete, Heraklion, Greece, 3Rheumatology, Clinical Immunology and Allergy Department, Medical School, University of Crete, Crete, Greece, 4Rheumatology, Clinical Immunology and Allergy Department, Medical School, University of Crete, Greece; Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology Hellas (FORTH), Heraklion, Greece

    Background/Purpose: Early detection of difficult to treat (D2T) RA patients as well as better characterization of their long-term course represent unresolved issues. Herein we aimed…
  • Abstract Number: 1167 • ACR Convergence 2023

    Transcriptome Analysis of Peripheral Blood Reveals Superiority of the Triple Combination of Baricitinib, Rituximab, and Tacrolimus Therapy (BRT-Tx.) for anti-MDA5 Antibody-positive Dermatomyositis (MDA5-DM)

    Yoshinobu Koyama1, Yoshiharu Sato2, Yu Nakai3 and Moe Tokunaga(Sakamoto)3, 1Japanese Red Cross Okayama Hospital, Okayama, Japan, 2DNA Chip Research Inc, Tokyo, Japan, 3Rheumatology, Center for Autoimmune diseases, Japanese Red Cross Okayama Hospital, Okayama, Japan

    Background/Purpose: MDA5-DM is characterized by high mortality due to rapid progressive ILD. We reported that in MDA-5DM, (1) RIG-1-like receptor signaling is enhanced, (2) antiviral…
  • Abstract Number: 1972 • ACR Convergence 2023

    Evaluation of Myositis Autoantibodies as Predictors of Response to IVIG: Post-hoc Analysis of a Large Randomized, Double-Blind, Placebo-Controlled Phase III Trial

    Christina Charles-Schoeman1, Joachim Schessl2, Rohit Aggarwal3 and and the ProDERM investigators4, 1UCLA Medical Center, Santa Monica, CA, 2Friedrich-Baur-Institute, Ludwig-Maximilians University of Munich, Munich, Germany, 3University of Pittsburgh, Pittsburgh, PA, 4Institutions in Europe and North America, Vienna, Austria

    Background/Purpose: Dermatomyositis (DM) is an immune-mediated inflammatory myopathy (IIM). Two subsets ofautoantibodies have been identified in patients with IIM: Myositis-specific antibodies (MSA) and myositis-associated antibodies…
  • Abstract Number: 2561 • ACR Convergence 2023

    The Prognostic Value of the “2022 ACR/EULAR Classification Criteria for Giant Cell Arteritis”: Data from the Italian Society of Rheumatology Vasculitis Study Group

    Alessandro Tomelleri1, Corrado Campochiaro2, Francesco Muratore3, Sara Monti4, Nicola Farina5, Chiara Marvisi6, Elena Galli7, Alessandra Milanesi8, Naomi Viapiana5, Alvise Berti9, Roberto Bortolotti9, Milena Bond10, Roberto Padoan11, Mara Felicetti9, Franco Schiavon12, Carlotta Nannini13, Fabrizio Cantini13, Alessandro Giollo14, Maurizio Rossini15, Edoardo Conticini16, Bruno Frediani17, Fabrizio Conti18, Roberta Priori18, Marco Sebastiani19, Giulia Cassone20, Luca Quartuccio Quartuccio21, Elena Treppo22, Silvano Bettio23, Ariela Hoxha24, Marco Lovisotto24, Giacomo Emmi25, irene mattioli26, Pietro Leccese27, Roberto F. Caporali28, Lorenza Maria Argolini29, Rosario Foti30, Elisa Visalli30, Michele Colaci31, Carlomaurizio Montecucco32, Lorenzo Dagna33 and Carlo Salvarani34, 1Unit of Immunology, Rheumatology, Allergy and Rare Diseases, San Raffaele Scientific Institute, Milano, Italy, 2IRCCS San Raffaele Hospital, Unit of Immunology, Rheumatology, Allergy and Rare Disease. Vita-Salute San Raffaele University, Milan, Italy, 3IRCCS di Reggio Emilia, Reggio Emilia, Italy, 4Division of Rheumatology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy; Department of Internal Medicine and Therapeutics, Università di Pavia, Pavia, Italy, 5IRCCS San Raffaele Hospital, Milan, Italy, 6IRCCS di Reggio Emilia, Reggio Emilia, Italy, Reggio Emilia, Italy, 7Azienda Unità Sanitaria Locale-IRCCS Di Reggio Emilia, Reggio Emilia, Italy, 8Fondazione IRCCS Policlinico San Matteo, Pavia, Italy, 9Santa Chiara Hospital of Trento, Trento, Italy, 10Azienda sanitaria dell'Alto Adige, Merano, Italy, 11Department of Medicine DIMED, University of Padova, Padova, Italy, 12University of Padova, Padova, Italy, 13Santo Stefano Hospital Prato, Prato, Italy, 14Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, Padua, Italy, 15Rheumatology Unit, Department of Medicine, University of Verona, Verona, Italy, 16Tallaght University Hospital, Dublin, Ireland, 17University of Siena, Siena, Italy, 18University of Rome La Sapienza, Rome, Italy, 19Azienda Policlinico di Modena, Modena, Italy, 20University of Modena and Reggio Emilia, Modena, Italy, 21Rheumatology Division, Department of Medicine, University of Udine, Udine, Italy, 22Physician, Moimacco, Italy, 23University of Padua, Treviso, Italy, 24San Bortolo Hospital of Vicenza, Vicenza, Italy, 25University of Florence, Florence, Italy, 26University of Florence, Firenze, Italy, 27Regional Hospital San Carlo, Potenza, Italy, 28Department of Clinical Sciences and Community Health, University of Milan, and Department of Rheumatology and Medical Sciences, ASST Gaetano Pini-CTO, Milano, Italy, 29ASST Gaetano Pini, Milano, Italy, 30AOU San Marco, Catania, Catania, Italy, Catania, Italy, 31University of Catania, Catania, Italy, 32Unità Operativa e Cattedra di Reumatologia, IRCCS Policlinico S Matteo, Pavia, Italy, 33Ospedale San Raffaele, Milano, Italy, 34Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy

    Background/Purpose: The 2022 classification criteria for giant cell arteritis (GCA) have been recently published. The aim of this study is to investigate whether the score…
  • Abstract Number: 0392 • ACR Convergence 2023

    Novel Diagnostic Markers for Rheumatoid Arthritis Including Anti-CarP (Carbamylated Protein), Anti-Sa (Citrullinated Vimentin) and Anti-CEP1 (Citrullinated Enolase Peptide1) Are Frequently Positive in Diagnostic Profiles

    Jane Yang1, Rubio Punzalan1, Lehrhoff Andrew1, Michael Nappi1, Vincent ricchiuti2, Michael Zikry1 and Kelly Chun1, 1Labcorp, Calabasas, CA, 2Labcorp, Dublin, OH

    Background/Purpose: Despite the diagnostic contribution of Anti-CCP3.1 (cyclic citrillunated peptide) antibody and RF (rheumatoid factor) as classified by the 2010 ACR/EULAR RA criteria, approximately one-third…
  • Abstract Number: 1169 • ACR Convergence 2023

    All-cause Mortality and Risk Factors for Death in a Large Multi-center Prospective Registry Cohort of Idiopathic Inflammatory Myositis in China

    Liying Peng1, Peng Yin2, Mucong Li3, Qian Wang4, Yanhong wang1, Shuang Zhou4, chanyuan wu4, Jiuliang zhao1, Dong xu5, Mengtao Li3 and xiaofeng Zeng4, 1Peking Union Medical College, Beijing, China, 2Chinese Center for Disease Control and Prevention, Beijing, China, 3Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China, 4Department of Rheumatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China, 5Peking Union Medical College Hospital, Beijing, China

    Background/Purpose: Our study depicted the mortality and independent risk factors of IIM patients in a large multi-center prospective registry cohort in China. Methods: Patients registered…
  • Abstract Number: 2108 • ACR Convergence 2023

    Specific Symptom Clusters at Diagnosis Signal a Poorer Early RA Prognosis: Data from the Canadian Early Arthritis Cohort (CATCH)

    Susan Bartlett1, Clifton Bingham2, Orit Schieir3, Marie-France Valois4, Janet Pope5, Louis Bessette6, Gilles Boire7, Carol Hitchon8, Edward Keystone9, Carter Thorne10, Diane Tin11, Glen Hazlewood12 and Vivian Bykerk13, 1McGill University, Montreal, QC, Canada, 2Johns Hopkins Medicine, Baltimore, MD, 3McGill University, Montréal, QC, Canada, 4McGill University, Pointe-Claire, QC, Canada, 5University of Western Ontario, London, ON, Canada, 6Centre de l'Ostéoporose et de Rhumatologie de Québec, Quebec City, QC, Canada, 7Université de Sherbrooke, Sherbrooke, QC, Canada, 8University of Manitoba, Winnipeg, MB, Canada, 9Keystone Consulting Enterprises Inc., Toronto, ON, Canada, 10Southlake Regional Health Centre, Newmarket, ON, Canada, 11Newmarket Rheumatology Consultants, Newmarket, ON, Canada, 12University of Calgary, Calgary, AB, Canada, 13Hospital for Special Surgery, New York, NY

    Background/Purpose: Symptom clusters are stable groups of 2+ symptoms that are related to each other and frequently co-occur. Identifying symptom clusters in early RA may…
  • Abstract Number: 0406 • ACR Convergence 2023

    Obesity Is a Risk Factor for Poor Response to Treatment in Early Rheumatoid Arthritis – a NORD-STAR Spin-Off Study

    Violetta Dubovyk1, Gerdur Maria Grondal2, Bjorn Gudbjornsson3, Espen A Haavardsholm4, Marte Schrumpf Heiberg4, Merete Hetland5, Kim Hørslev-Petersen6, Meliha Kapetanovic7, Alf Kastbom8, John Lampa9, Kristina Lend10, Dan Nordstrom11, Michael Nurmohamed12, Milad Rizk13, Annika Söderbergh14, Till Uhlig15, Mikkel Østergaard16, Ronald van Vollenhoven12, Anna Rudin17 and Cristina Maglio18, 1University of Gothenburg, Gothenburg, Sweden, 2Department for Rheumatology, Landspitali University Hospital, Reykjavik, Iceland, 3Centre for Rheumatology Research, University Hospital, Reykjavik, Iceland, 4Diakonhjemmet Hospital, Oslo, Norway, 5Copenhagen Center for Arthritis Research, Rigshospitalet, Copenhagen, Denmark, 6University of Southern Denmark, Odense, Denmark, 7Lund University and Skåne University Hospital, Lund, Sweden, 8Linköping University, Linköping, Sweden, 9Stockholm County, Hãsselby, Sweden, 10Amsterdam UMC, Karolinska Institute, Stockholm, Sweden, 11Helsinki University Hospital, Helsinki, Finland, 12Amsterdam University Medical Centers, Amsterdam, Netherlands, 13Västmanlands Hospital Västerås, Västerås, Sweden, 14Örebro University Hospital, Örebro, Sweden, 15Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway, 16Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet; University of Copenhagen, Copenhagen, Denmark, 17Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden, 18Institute of Medicine, University of Gothenburg, Gothenburg, Sweden

    Background/Purpose: Several therapeutic options are currently available to treat rheumatoid arthritis (RA); however, the response to treatment is highly variable, and not all patients achieve…
  • Abstract Number: 1172 • ACR Convergence 2023

    Relapse Rate After Glucocorticoid-free Remission in Idiopathic Inflammatory Myopathies with Validation of the International Myositis Assessment & Clinical Studies Group (IMACS) Criteria for Remission and Relapse

    Hideaki Tsuji1, Fabricio Espinosa-Ortega2, Maryam Dastmalchi2, Ingrid Lundberg2 and Karin Lodin3, 1Division of Rheumatology, Department of Medicine, Karolinska Institutet; Department of Rheumatology and Clinical Immunology, Kyoto University Graduate School of Medicine, Kyoto, Japan, 2Division of Rheumatology, Department of Medicine, Karolinska Institutet; Department of Gastroenterology, Dermatotology, Rhematology, Karolinska Universitetssjukhuset, Stockholm, Sweden, 3Division of Rheumatology, Department of Medicine, Karolinska Institutet; Department of Gastroenterology, Dermatotology, Rhematology, Karolinska Universitetssjukhuset, Huddinge, Sweden

    Background/Purpose: Our aim was to explore whether maintenance of remission in patients with idiopathic inflammatory myopathy (IIM) depends on glucocorticoids (GCs) after achieving remission. Therefor…
  • Abstract Number: 2115 • ACR Convergence 2023

    Genetic Risk Load as a Predictor of Radiographic Damage and Mortality in Female Patients with Rheumatoid Arthritis

    Jihye Kim1, Yeon-Kyung Lee2, Youngho Park3, Ayeong Kwon4, Young-Chang Kwon1, Young Bin Joo2, Hye-Soon Lee5, Kwangwoo Kim4, Sang-Cheol Bae6 and So-Young Bang2, 1Hanyang University Institute for Rheumatology Research, Seoul, South Korea, 2Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, 3Department of Business Statistics, Hannam University, Daejeon, South Korea, 4Department of Biology, Kyung Hee University, Seoul, South Korea, 5Hanyang University, Guri, South Korea, 6Hanyang University Hospital for Rheumatic Diseases and Hanyang University Institute for Rheumatology Research, Department of Rheumatology, Seoul, South Korea

    Background/Purpose: Rheumatoid arthritis (RA) is an autoimmune disease characterized by an unpredictable prognosis and increased mortality risk. Although the role of genetics in RA mortality…
  • Abstract Number: 0489 • ACR Convergence 2023

    Prediction of Low Disease Activity in Patients with Psoriatic Arthritis Treated with Secukinumab in Real World – Data from a German Observational Study

    Asmir Vodencarevic1, Jan Brandt-Juergens2, Daniel Peterlik1, Benjamin Gmeiner1 and Uta Kiltz3, 1Novartis Pharma GmbH, Nürnberg, Germany, 2rheumatologische Schwerpunktpraxis, Berlin, Germany, 3Rheumazentrum Ruhrgebiet, Herne, Germany

    Background/Purpose: Secukinumab (SEC) proved to be an effective treatment for patients with psoriatic arthritis (PsA) in previous randomized clinical trials [1]. There is only limited…
  • Abstract Number: 1243 • ACR Convergence 2023

    Tubulointerstitial Inflammation Is Associated with End-Stage Renal Disease in Pediatric Lupus Nephritis: A Single Center Retrospective Cohort Study

    Ryan Mitacek, Qiong Liu, Linda Wagner-Weiner, Shireen Hashmat and Anthony Chang, University of Chicago, Chicago, IL

    Background/Purpose: Lupus nephritis (LN) is associated with significant morbidity and mortality. The 2018 International Society of Nephrology/Renal Pathology Society (ISN/RPS) classification criteria and the NIH…
  • Abstract Number: 2134 • ACR Convergence 2023

    Autoantibodies to Joint-related Proteins Predict Remission with High Specificity in New Onset RA

    Monica Leu Agelii1, Outi Sareila2, Erik Lönnblom2, Kristina Forslind3, Maria Andersson3, Alf Kastbom4, Christopher Sjöwall5, Lennart Jacobsson6, Jan Kihlberg7, Rikard Holmdahl2, Ingiäld Hafström2 and Inger Gjertsson8, 1Gothenburg University, Goteborg, Sweden, 2Karolinska Institutet, Stockholm, Sweden, 3FoU Spenshult, Halmstad, Sweden, 4Linköping University, Linköping, Sweden, 5Department of Biomedical and Clinical Sciences, Division of Inflammation and Infection/Rheumatology, Linköping University, Linköping, Sweden, 6University of Gothenburg, Malmö, Sweden, 7Uppsala University, Uppsala, Sweden, 8Department of Rheumatology and Inflammation research, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

    Background/Purpose: One of the major challenges in the management of rheumatoid arthritis (RA) is to determine individual treatment and predict the prognosis. On a group…
  • Abstract Number: 036 • 2023 Pediatric Rheumatology Symposium

    Predictive Factors of Long-lasting Remission Following Anakinra Withdrawal in Patients with Systemic Juvenile Idiopathic Arthritis After Achievement of Clinical Inactive Disease

    Germana Nardini1, Claudia Bracaglia2, Denise Pires Marafon1, Emanuela Sacco3, Arianna De Matteis1, Ivan Caiello1, Giusi Prencipe1, Fabrizio De Benedetti2 and Manuela Pardeo2, 1Division of Rheumatology, IRCCS Ospedale Pediatrico Bambino Gesu', Roma, Italy, 2Division of Rheumatology, IRCCS Ospedale Pediatrico Bambino Gesù, Roma, Italy, 3Fondazione Casa Sollievo della Sofferenza, Pediatria, San Giovanni Rotondo, Italy

    Background/Purpose: Systemic juvenile idiopathic arthritis (sJIA) is a rare autoinflammatory disease of unknown etiology. Several uncontrolled studies showed that early treatment with anakinra is associated…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. Academic institutions, private organizations and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part a scientific presentation or presentation of additional new information that will be available at the time of the meeting) is under embargo until Saturday, November 11, 2023.

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying financial and other sponsors about this policy. If you have questions about the abstract embargo policy, please contact the public relations department at [email protected].

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