Abstracts tagged "Prognostic factors and rheumatoid arthritis (RA)"

Abstract Number: 2522 • 2012 ACR/ARHP Annual Meeting
M-Ficolin, an Activator of the Complement System, Is the Strongest Predictor of Both DAS28 Remission and Low Disease Activity in a Cohort of 180 Early DMARD Naïve Rheumatoid Arthritis Patients Followed in the Opera-Study
Christian G. Ammitzbøll¹, Jens Christian Jensenius², Torkell Ellingsen³, Steffen Thiel², Kim Hørslev-Petersen⁴, Merete L. Hetland⁵, Peter Junker⁶, Julia Johansen⁷, Mikkel Østergaard⁸, Jan Pødenphant⁹ and Kristian Stengaard-Pedersen¹, ¹Arhus University Hospital, Aarhus, Denmark, ²Biomedicine, Aarhus University, Aarhus, Denmark, ³Silkeborg Regional Hospital, Silkeborg, Denmark, ⁴Institute of Regional Health Services Research, University of Southern Denmark, Graasten, Denmark, ⁵Copenhagen University Hospital Glostrup, Copenhagen, Denmark, ⁶Odense University Hospital, Odense, Denmark, ⁷Glostrup Hospital, Glostrup, Denmark, ⁸Copenhagen University Hospital Glostrup, Glostrup, Denmark, ⁹Gentofte Hospital
Background/Purpose: M-ficolin is a soluble pattern recognition molecule that activates the complement system. We recently reported a factor 300 difference in the synovial fluid M-ficolin…
Abstract Number: 2128 • 2012 ACR/ARHP Annual Meeting
Matrix Metalloproteinase 3: A Biomarker of Disease Activity in Rheumatoid Arthritis
Sandra Reuter¹, Torsten Matthias² and Bruno Larida³, ¹AIRA e.V., AESKU.KIPP Institute, Wendelsheim, Germany, ²AESKU.Diagnostics GmbH & Co. KG, Wendelsheim, Germany, ³AESKU.DIAGNOSTICS INC, Oakland, CA
Background/Purpose: New biomarkers for monitoring Rheumatoid Arthritis (RA) disease activity and prognosis of progression are urgently needed to individually optimize drug therapy and prevent joint…
Abstract Number: 2120 • 2012 ACR/ARHP Annual Meeting
Predictive Value of Anti-CCP Positivity On Disease Course and Response to Therapy in Early Rheumatoid Arthritis. Results From the Swedish EIRA Study
Saedis Saevarsdottir¹, Marie Holmqvist², Johan Askling³, Lars Alfredsson⁴ and Lars Klareskog⁵, ¹Rheumatology Unit, Dept. of Medicine, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden, ²Karolinska Institutet, Stockholm, Sweden, ³Department of Medicine, Rheumatology Unit & Clinical Epidemiology Unit, Karolinska Institute, Stockholm, Sweden, ⁴Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, ⁵Department of Medicine, Rheumatology Unit, Karolinska Institute, Stockholm, Sweden
Background/Purpose: Does anti-CCP-positivity predict disease course and response to therapy in early rheumatoid arthritis (RA)? Methods: We retrieved clinical follow-up data for patients entering the…
Abstract Number: 1830 • 2012 ACR/ARHP Annual Meeting
Drugs Are the Major Cost Driver of Rheumatoid Arthritis As Soon As the First Year of the Disease: An Economic Analysis Based On the Espoir Cohort Data
Bruno Fautrel¹, Sandy Lucier², Georges Haour², Hassani Maoulida², Stephanie Harvard¹, Alain Saraux³, Xavier Mariette⁴, Francis Guillemin⁵, Isabelle Durand-Zaleski² and Karine Chevreul², ¹Rheumatology / GRC08-EEMOIS, APHP-Pitie Salpetriere Hospital / UPMC, Paris, France, ²APHP - URC Eco, Paris, France, ³Department of rheumatology and unit of immunology (EA 2216), Université Brest Occidentale, Brest, France, ⁴Rheumatology, Université Paris-Sud, Le Kremlin Bicetre, France, ⁵Hopitaux de Brabois, Nancy, France
Background/Purpose: Many studies have explored the economic burden of established RA but few data are available about the determinants of costs in early rheumatoid arthritis…
Abstract Number: 1214 • 2012 ACR/ARHP Annual Meeting
The Impact of Periodontal Disease On Early Inflammatory Arthritis Persists Even After All Teeth Are Lost
Gisela Westhoff¹, Paola de Pablo², Thomas Dietrich³, Georg Schett⁴ and Angela Zink⁵, ¹Epidemiology Unit, German Rheumatism Research Center Berlin, Berlin, Germany, ²Rheumatology, College of Medical & Dental Sciences, IBR 3rd floor, University of Birmingham, Birmingham, United Kingdom, ³College of Medical and Dental Sciences, The School of Dentistry, University of Birmingham, Birmingham, UK, Birmingham, United Kingdom, ⁴Dept of Medicine 3, Rheumatology and Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany, ⁵German Rheumatism Research Centre and Charité University Medicine, Berlin, Germany
Background/Purpose: Data suggests that individuals with periodontal disease (PD) may be more likely to develop rheumatoid arthritis (RA) and have worse disease activity. PD is…
Abstract Number: 830 • 2012 ACR/ARHP Annual Meeting
Five-Year Favourable Outcome of Patients with Early Rheumatoid Arthritis in the 2000s: Data From the Espoir Cohort
Bernard G. Combe¹, Nathalie Rincheval², Joelle Benessiano³, Francis Berenbaum⁴, Alain G. Cantagrel⁵, Jean-Pierre Daurès², Maxime Dougados⁶, Patrice Fardellone⁷, Bruno Fautrel⁸, Rene-Marc Flipo⁹, Philippe M. Goupille¹⁰, Francis Guillemin¹¹, Xavier X. Le Loet¹², Isabelle Logeart¹³, Xavier Mariette¹⁴, Olivier Meyer¹⁵, Philippe Ravaud¹⁶, Alain Saraux¹⁷, Thierry Schaeverbeke¹⁸ and Jean Sibilia¹⁹, ¹Rhumatologie, Hopital Lapeyronie, Montpellier, France, ²Institut Universitaire de Recherche Clinique, Montpellier, France, ³Rheumatology, Paris Unervisity Hospital BICHAT, Paris, France, ⁴Rheumatology, AP-HP, St Antoine Hospital, Paris, France, ⁵Dept of Rheumatology, Hopital Purpan, Toulouse CEDEX 9, France, ⁶Rheumatology B Department, Paris-Descartes University, APHP, Cochin Hospital, Paris, France, ⁷Service de Rhumatologie, C.H.U. D'Amiens, Amiens, France, ⁸Rheumatology / GRC08-EEMOIS, APHP-Pitie Salpetriere Hospital / UPMC, Paris, France, ⁹Rheumatology, Hopital R Salengro CHRU, Lille, France, ¹⁰Rheumatology, Hopital Trousseau, Tours, France, ¹¹Ecole de Sante Publique, Faculte de Medecin/BP 184, Vandoeuvre-les-Nancy, France, ¹²Rheumatology Department, CHU de ROUEN, Rouen, France, ¹³Pfizer, Paris, France, ¹⁴Rheumatology, Université Paris-Sud, Le Kremlin Bicetre, France, ¹⁵Rheumatology, Hopital Bichat, Paris, France, ¹⁶Rheumatology Department, Hotel Dieu University hospital, Paris, France, ¹⁷Rhumatologie, CHU de la Cavale Blanche, Brest Cedex, France, ¹⁸Service de Rhumatologie, Groupe Hospitalier Pellegrin, Bordeaux, France, ¹⁹Rhumatologie, CHU Hautepierre, Strasbourg, France
Background/Purpose: To report the five-year outcome of a large national multicentre, longitudinal and prospective cohort of patients with very early arthritis and rheumatoid arthritis (RA)…
Abstract Number: 363 • 2012 ACR/ARHP Annual Meeting
Risk Factors for Radiographic Progression During TNF-Inhibitor Treatment in 932 Rheumatoid Arthritis Patients Treated in Clinical Practice: Results From the Nationwide Danish Danbio Registry
Lykke Midtbøll Ørnbjerg¹, Mikkel Østergaard¹, Pernille Bøyesen², Anja Thormann¹, Ulrik Tarp¹, Wolfgang Bøhme¹, Ditte Dencker¹, Hanne M. Lindegaard³, Uta Engling Poulsen¹, Annette Hansen⁴, Vibeke Stevenius Ringsdal¹, Annette Schlemmer⁵, Niels Graudal¹, Anne Rødgaard Andersen¹, Jakob Espesen¹, Gina Kollerup¹, Torben Grube Christensen¹, Randi Pelck¹, Bente Glintborg¹, Ole Rintek Madsen¹, Dorte Vendelbo Jensen¹, Ole Majgaard¹ and Merete L. Hetland⁶, ¹DANBIO, On behalf of Depts of Rheumatology, North, South, Central, Zealand and Capital Region, Copenhagen, Denmark, ²Rheumatology, Diakonhjemmet Hospital, Olso, Norway, ³Department of Rheumatology, Odense University Hospital, Odense, Denmark, ⁴Department of Rheumatology, Gentofte University Hospital, Copenhagen, Denmark, ⁵Department of Rheumatology, Aalborg University Hospital, Aalborg, Denmark, ⁶Copenhagen University Hospital Glostrup, Copenhagen, Denmark
Background/Purpose: : Despite treatment with tumour necrosis factor inhibitors (TNFi) some rheumatoid arthritis (RA) patients progress radiographically in randomised controlled trials and observational cohorts (1).…

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