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Abstracts tagged "Prognostic factors and rheumatoid arthritis (RA)"

  • Abstract Number: 1214 • 2012 ACR/ARHP Annual Meeting

    The Impact of Periodontal Disease On Early Inflammatory Arthritis Persists Even After All Teeth Are Lost

    Gisela Westhoff1, Paola de Pablo2, Thomas Dietrich3, Georg Schett4 and Angela Zink5, 1Epidemiology Unit, German Rheumatism Research Center Berlin, Berlin, Germany, 2Rheumatology, College of Medical & Dental Sciences, IBR 3rd floor, University of Birmingham, Birmingham, United Kingdom, 3College of Medical and Dental Sciences, The School of Dentistry, University of Birmingham, Birmingham, UK, Birmingham, United Kingdom, 4Dept of Medicine 3, Rheumatology and Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany, 5German Rheumatism Research Centre and Charité University Medicine, Berlin, Germany

    Background/Purpose: Data suggests that individuals with periodontal disease (PD) may be more likely to develop rheumatoid arthritis (RA) and have worse disease activity. PD is…
  • Abstract Number: 830 • 2012 ACR/ARHP Annual Meeting

    Five-Year Favourable Outcome of Patients with Early Rheumatoid Arthritis in the 2000s: Data From the Espoir Cohort

    Bernard G. Combe1, Nathalie Rincheval2, Joelle Benessiano3, Francis Berenbaum4, Alain G. Cantagrel5, Jean-Pierre Daurès2, Maxime Dougados6, Patrice Fardellone7, Bruno Fautrel8, Rene-Marc Flipo9, Philippe M. Goupille10, Francis Guillemin11, Xavier X. Le Loet12, Isabelle Logeart13, Xavier Mariette14, Olivier Meyer15, Philippe Ravaud16, Alain Saraux17, Thierry Schaeverbeke18 and Jean Sibilia19, 1Rhumatologie, Hopital Lapeyronie, Montpellier, France, 2Institut Universitaire de Recherche Clinique, Montpellier, France, 3Rheumatology, Paris Unervisity Hospital BICHAT, Paris, France, 4Rheumatology, AP-HP, St Antoine Hospital, Paris, France, 5Dept of Rheumatology, Hopital Purpan, Toulouse CEDEX 9, France, 6Rheumatology B Department, Paris-Descartes University, APHP, Cochin Hospital, Paris, France, 7Service de Rhumatologie, C.H.U. D'Amiens, Amiens, France, 8Rheumatology / GRC08-EEMOIS, APHP-Pitie Salpetriere Hospital / UPMC, Paris, France, 9Rheumatology, Hopital R Salengro CHRU, Lille, France, 10Rheumatology, Hopital Trousseau, Tours, France, 11Ecole de Sante Publique, Faculte de Medecin/BP 184, Vandoeuvre-les-Nancy, France, 12Rheumatology Department, CHU de ROUEN, Rouen, France, 13Pfizer, Paris, France, 14Rheumatology, Université Paris-Sud, Le Kremlin Bicetre, France, 15Rheumatology, Hopital Bichat, Paris, France, 16Rheumatology Department, Hotel Dieu University hospital, Paris, France, 17Rhumatologie, CHU de la Cavale Blanche, Brest Cedex, France, 18Service de Rhumatologie, Groupe Hospitalier Pellegrin, Bordeaux, France, 19Rhumatologie, CHU Hautepierre, Strasbourg, France

    Background/Purpose: To report the five-year outcome of a large national multicentre, longitudinal and prospective cohort of patients with very early arthritis and rheumatoid arthritis (RA)…
  • Abstract Number: 363 • 2012 ACR/ARHP Annual Meeting

    Risk Factors for Radiographic Progression During TNF-Inhibitor Treatment in 932 Rheumatoid Arthritis Patients Treated in Clinical Practice: Results From the Nationwide Danish Danbio Registry

    Lykke Midtbøll Ørnbjerg1, Mikkel Østergaard1, Pernille Bøyesen2, Anja Thormann1, Ulrik Tarp1, Wolfgang Bøhme1, Ditte Dencker1, Hanne M. Lindegaard3, Uta Engling Poulsen1, Annette Hansen4, Vibeke Stevenius Ringsdal1, Annette Schlemmer5, Niels Graudal1, Anne Rødgaard Andersen1, Jakob Espesen1, Gina Kollerup1, Torben Grube Christensen1, Randi Pelck1, Bente Glintborg1, Ole Rintek Madsen1, Dorte Vendelbo Jensen1, Ole Majgaard1 and Merete L. Hetland6, 1DANBIO, On behalf of Depts of Rheumatology, North, South, Central, Zealand and Capital Region, Copenhagen, Denmark, 2Rheumatology, Diakonhjemmet Hospital, Olso, Norway, 3Department of Rheumatology, Odense University Hospital, Odense, Denmark, 4Department of Rheumatology, Gentofte University Hospital, Copenhagen, Denmark, 5Department of Rheumatology, Aalborg University Hospital, Aalborg, Denmark, 6Copenhagen University Hospital Glostrup, Copenhagen, Denmark

    Background/Purpose: : Despite treatment with tumour necrosis factor inhibitors (TNFi) some rheumatoid arthritis (RA) patients progress radiographically in randomised controlled trials and observational cohorts (1).…
  • Abstract Number: 2522 • 2012 ACR/ARHP Annual Meeting

    M-Ficolin, an Activator of the Complement System, Is the Strongest Predictor of Both DAS28 Remission and Low Disease Activity in a Cohort of 180 Early DMARD Naïve Rheumatoid Arthritis Patients Followed in the Opera-Study

    Christian G. Ammitzbøll1, Jens Christian Jensenius2, Torkell Ellingsen3, Steffen Thiel2, Kim Hørslev-Petersen4, Merete L. Hetland5, Peter Junker6, Julia Johansen7, Mikkel Østergaard8, Jan Pødenphant9 and Kristian Stengaard-Pedersen1, 1Arhus University Hospital, Aarhus, Denmark, 2Biomedicine, Aarhus University, Aarhus, Denmark, 3Silkeborg Regional Hospital, Silkeborg, Denmark, 4Institute of Regional Health Services Research, University of Southern Denmark, Graasten, Denmark, 5Copenhagen University Hospital Glostrup, Copenhagen, Denmark, 6Odense University Hospital, Odense, Denmark, 7Glostrup Hospital, Glostrup, Denmark, 8Copenhagen University Hospital Glostrup, Glostrup, Denmark, 9Gentofte Hospital

    Background/Purpose: M-ficolin is a soluble pattern recognition molecule that activates the complement system. We recently reported a factor 300 difference in the synovial fluid M-ficolin…
  • Abstract Number: 2128 • 2012 ACR/ARHP Annual Meeting

    Matrix Metalloproteinase 3: A Biomarker of Disease Activity in Rheumatoid Arthritis

    Sandra Reuter1, Torsten Matthias2 and Bruno Larida3, 1AIRA e.V., AESKU.KIPP Institute, Wendelsheim, Germany, 2AESKU.Diagnostics GmbH & Co. KG, Wendelsheim, Germany, 3AESKU.DIAGNOSTICS INC, Oakland, CA

    Background/Purpose: New biomarkers for monitoring Rheumatoid Arthritis (RA) disease activity and prognosis of progression are urgently needed to individually optimize drug therapy and prevent joint…
  • Abstract Number: 2120 • 2012 ACR/ARHP Annual Meeting

    Predictive Value of Anti-CCP Positivity On Disease Course and Response to Therapy in Early Rheumatoid Arthritis. Results From the Swedish EIRA Study

    Saedis Saevarsdottir1, Marie Holmqvist2, Johan Askling3, Lars Alfredsson4 and Lars Klareskog5, 1Rheumatology Unit, Dept. of Medicine, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden, 2Karolinska Institutet, Stockholm, Sweden, 3Department of Medicine, Rheumatology Unit & Clinical Epidemiology Unit, Karolinska Institute, Stockholm, Sweden, 4Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, 5Department of Medicine, Rheumatology Unit, Karolinska Institute, Stockholm, Sweden

    Background/Purpose: Does anti-CCP-positivity predict disease course and response to therapy in early rheumatoid arthritis (RA)? Methods: We retrieved clinical follow-up data for patients entering the…
  • Abstract Number: 1830 • 2012 ACR/ARHP Annual Meeting

    Drugs Are the Major Cost Driver of Rheumatoid Arthritis As Soon As the First Year of the Disease: An Economic Analysis Based On the Espoir Cohort Data

    Bruno Fautrel1, Sandy Lucier2, Georges Haour2, Hassani Maoulida2, Stephanie Harvard1, Alain Saraux3, Xavier Mariette4, Francis Guillemin5, Isabelle Durand-Zaleski2 and Karine Chevreul2, 1Rheumatology / GRC08-EEMOIS, APHP-Pitie Salpetriere Hospital / UPMC, Paris, France, 2APHP - URC Eco, Paris, France, 3Department of rheumatology and unit of immunology (EA 2216), Université Brest Occidentale, Brest, France, 4Rheumatology, Université Paris-Sud, Le Kremlin Bicetre, France, 5Hopitaux de Brabois, Nancy, France

    Background/Purpose: Many studies have explored the economic burden of established RA but few data are available about the determinants of costs in early rheumatoid arthritis…
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