Abstracts tagged "positron emission tomography (PET)"

Abstract Number: 062 • 2020 Pediatric Rheumatology Symposium
Is Positron Emission Tomography/Magnetic Resonance Imaging (PET/MRI) a Reliable Tool for Detecting Vascular Activity in Treated Childhood-Onset Takayasu’s Arteritis (C-TA)? A Multicenter Study
Gleice Russo¹, Rosa Pereira ², Nadia Aikawa ³, Clovis Silva ⁴, Lucia Campos ⁵, Ana Paula Sakamoto ⁶, Alexandre Souza ⁷ and Maria Teresa Terreri ⁴, ¹Universidade Federal de Sao Paulo, Sao Paulo, Sao Paulo, Brazil, ²University of São Paulo, Sao Paulo, Brazil, ³University of Sao Paulo, Sao Paulo, Brazil, ⁴Sao Paulo, Brazil, ⁵children's institute, Sao Paulo, Brazil, ⁶São Paulo, Brazil, ⁷UNIFESP-EPM, São Paulo, Brazil
Background/Purpose: The improving therapeutic approach towards childhood-onset Takayasu’s arteritis (c-TA) has decreased the mortality rate over the years and increased concerns on how to improve…
Abstract Number: 106 • 2020 Pediatric Rheumatology Symposium
Childhood-onset Takayasu Arteritis: A Single Center Case Series of Atypical and Varied Presentations
Uptej Khalsa¹ and Imelda Balboni ¹, ¹Stanford University, Palo Alto, California
Background/Purpose: Childhood-onset Takayasu arteritis is a rare inflammatory vessel disease that predominantly affects the aorta and its major branches. Clinical presentation at disease onset can…
Abstract Number: 2922 • 2019 ACR/ARP Annual Meeting
Imaging Acquisition Technique Influences Interpretation of Positron Emission Tomography Vascular Activity in Large-Vessel Vasculitis
Kaitlin Quinn¹, Joel S. Rosenblum ², Casey A. Rimland ³, K Bates Gribbons ⁴, Mark A. Ahlman ⁵ and Peter C. Grayson ⁶, ¹Georgetown University Hospital/National Institutes of Health, Washington, DC, ²National Institute of Arthritis, Musculoskeletal and Skin Disease (NIAMS), Bethesda, MD, Bethesda, MD, ³National Institute of Arthritis, Musculoskeletal and Skin Disease (NIAMS), Bethesda, MD, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, Chapel Hill, NC, ⁴National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, ⁵Radiology and Imaging Sciences, National Institutes of Health, Bethesda, MD, Bethesda, MD, ⁶National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) of the National Institutes of Health, Bethesda, MD, Bethesda, MD
Background/Purpose: 18F-flurodeoxyglucose (FDG) positron emission tomography (PET) is one of several imaging modalities used in the assessment of patients with large-vessel vasculitis (LVV). Conventionally PET…
Abstract Number: 257 • 2017 ACR/ARHP Annual Meeting
The Use of Positron Emission Tomography (PET)-Scan for the Quantitative Assessment of Interstitial Lung Disease in Systemic Sclerosis
Daphne Peelen¹, Ben Zwezerijnen², Esther Nossent¹, Lilian Meijboom¹, Otto Hoekstra³, Conny van der Laken⁴ and Alexandre Voskuyl⁴, ¹VUmc, Amsterdam, Netherlands, ²Nuclear Medicine, VUmc, Amsterdam, Netherlands, ³Department of Radiology & Nuclear Medicine, VU University Medical Center, Amsterdam, The Netherlands, Amsterdam, Netherlands, ⁴Department of Rheumatology, Amsterdam Rheumatology and immunology Center - location VU University Medical Center, Amsterdam, The Netherlands, Amsterdam, Netherlands
Background/Purpose: Interstitial lung disease (ILD) in systemic sclerosis is treated by immunosuppressive drugs (e.g. cyclophosphamide), aimed at reduction of inflammatory response . Differentiation between inflamed…
Abstract Number: 820 • 2017 ACR/ARHP Annual Meeting
Prognostic Value of Positron Emission Tomography in a Prospective, Longitudinal Cohort of Patients with Large Vessel Vasculitis
Peter C. Grayson¹, Sara Alehashemi², Armin Bagheri³, Ali Cahid Civelek⁴, Thomas Cupps⁵, Mariana J. Kaplan⁶, Ashkan Malayeri⁴, Peter A. Merkel⁷, Elaine Novakovich⁸, David A. Bluemke⁴ and Mark Ahlman⁴, ¹National Institute of Arthritis, Musculoskeletal and Skin Disease (NIAMS), Bethesda, MD, ²Rheumatology, National Institutes of Health, Bethesda, MD, ³Vasculitis Translational Research Program, NIAMS, NIH, Bethesda, MD, ⁴Radiology and Imaging Sciences, National Institutes of Health, Bethesda, MD, ⁵Rheumatology, Georgetown University, Bethesda, MD, ⁶NIAMS/NIH, Bethesda, MD, ⁷University of Pennsylvania, Philadelphia, MN, ⁸Systemic Autoimmunity Branch, NIAMS, National Institutes of Health, Bethesda, MD
Background/Purpose: While several studies have examined the potential of 18F-flurodeoxyglucose (FDG) positron emission tomography (PET) to help establish a diagnosis of large vessel vasculitis (LVV),…
Abstract Number: 821 • 2017 ACR/ARHP Annual Meeting
Discrepancies between Clinical- and Imaging-Based Assessments of Disease Activity in Takayasu’s Arteritis
Peter C. Grayson¹, Mark Ahlman², Kathleen Marinelli³, Renee Borchin⁴, Simon Carette⁵, Nader A. Khalidi⁶, Carol A. Langford⁷, Carol A. McAlear⁸, Paul A. Monach⁹, Christian Pagnoux⁵, Kenneth J. Warrington¹⁰, Steven R. Ytterberg¹⁰ and Peter A. Merkel¹¹, ¹National Institute of Arthritis, Musculoskeletal and Skin Disease (NIAMS), Bethesda, MD, ²Radiology and Imaging Sciences, National Institutes of Health, Bethesda, MD, ³NIAMS, National Institutes of Health, Bethesda, MD, ⁴University of South Florida, Tampa, FL, ⁵Division of Rheumatology, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, ⁶Rheumatology, McMaster University, Hamilton, ON, Canada, ⁷Rheumatic and Immunologic Diseases, Cleveland Clinic, Cleveland, OH, ⁸University of Pennsylvania, Philadelphia, PA, ⁹Boston University School of Medicine, Boston, MA, ¹⁰Rheumatology, Mayo Clinic, Rochester, MN, ¹¹Biostatistics, Epidemiology, and Informatics, University of Pennsylvania, Philadelphia, PA
Background/Purpose: To study the relationship between clinically-determined disease activity and vascular inflammation assessed by positron emission tomography (PET) in patients with TakayasuÕs arteritis (TAK). Methods:…
Abstract Number: 907 • 2016 ACR/ARHP Annual Meeting
Rituximab in Patients with Takayasu Arteritis: A Single Center Experience on Five Patients
Giulia Pazzola¹, Francesco Muratore¹, Luigi Boiardi², Mariagazia Catanoso¹, Alessandra Soriano³, Pierluigi Macchioni¹, Lucia Spaggiari⁴, Massimiliano Casali⁵, Nicolò Pipitone¹, Niccolò Possemato⁶ and Carlo Salvarani¹, ¹Rheumatology Unit, Arcispedale S Maria Nuova, IRCCS, Reggio Emilia, Italy, ²Rheumatology Unit, Arcispedale S.Maria Nuova, IRCCS, Reggio Emilia, Italy, ³Rheumatology Unti, Arcispedale S Maria Nuova, IRCCS, Reggio Emilia, Italy, ⁴Radiology, Arcispedale S Maria Nuova, IRCCS, Reggio Emilia, Italy, ⁵Nuclear Medicine, Arcispedale S Maria Nuova, IRCCS, Reggio Emilia, Italy, ⁶Rheumatology Service, Arcispedale S Maria Nuova, IRCCS, Reggio Emilia, Italy
Background/Purpose: Takayasu arteritis (TAK) is a large vessel vasculitis involving the aorta and its major branches in patients younger than 40 years. Glucocorticoids (GCs) are…
Abstract Number: 1319 • 2015 ACR/ARHP Annual Meeting
18F-Fluorodeoxyglucose Positron Emission Computer Tomography and Ultrasonography for Assessing Remission in Patients with Rheumatoid Arthritis
Charline Rinkin¹, Pacôme Fosse², Nathalie Chapelier¹, Laurence Seidel³, Adelin Albert³, Roland Hustinx⁴ and Michel Malaise¹, ¹Rheumatology Department, CHU of Liège, Liège, Belgium, ²Nuclear Medicine Department, CHU of Angers, Angers, France, ³Biostatistic Department, CHU of Liège, Liège, Belgium, ⁴Nuclear Medicine Department, CHU of Liège, Liège, Belgium
Background/Purpose: The disease activity score based on 28 joints (DAS-28) might not be sufficient to assess remission in rheumatoid arthritis (RA). Several studies have shown…
Abstract Number: 2127 • 2014 ACR/ARHP Annual Meeting
Subclinical Arthritis Is Detected By Macrophage Targeting and Positron Emission Tomography (PET) in Early RA Patients in Clinical Remission
Y.Y.J. Gent¹, M.M. ter Wee¹, D den Uyl¹, N. Ahmadi², W.F. Lems³, O.S. Hoekstra⁴, A.E. Voskuyl¹ and C.J. Van der Laken³, ¹Rheumatology, VU University Medical Center, Amsterdam, Netherlands, ²Radiology, VU University Medical Center, Amsterdam, Netherlands, ³Rheumatology, VU Medical Center, Amsterdam, Netherlands, ⁴Nuclear Medicine, VU Medical Center, Amsterdam, Netherlands
Background/Purpose: Recurrent flares in RA patients in complete remission (CR) are not an uncommon phenomenon. Studies with advanced imaging techniques have suggested that residual subclinical…
Abstract Number: 513 • 2014 ACR/ARHP Annual Meeting
Analysis of Shoulder Joint Destruction in Rheumatoid Arthritis Patients Treated with Biologics
Yukio Yonemoto, Koichi Okamura, Tetsuya Kaneko, Chisa Okura and Kenji Takagishi, Department of Orthopaedic Surgery, Gunma University Graduate School of Medicine, Maebashi, Japan
Background/Purpose The assessment of joint destruction in rheumatoid arthritis (RA) patients being treated with biologics is normally mainly carried out for small joints. There are…
Abstract Number: 2133 • 2014 ACR/ARHP Annual Meeting
Efficacy of Tocilizumab Therapy in Patients with Rheumatoid Arthritis Based on FDG-PET/CT
Koichi Okamura¹, Yukio Yonemoto¹, Chisa Okura² and Kenji Takagishi¹, ¹Orthopaedic Surgery, Gunma University, Maebashi, Japan, ²Department of Orthopaedic Surgery, Gunma University Graduate School of Medicine, Maebashi, Japan
Background/Purpose: A humanized anti-interleukin-6 receptor (anti-IL-6R) antibody, tocilizumab (TCZ), is one of the biologics and the C-reactive protein (CRP) level and erythrocyte sedimentation rate (ESR)…
Abstract Number: 219 • 2013 ACR/ARHP Annual Meeting
Contrast-Enhanced Ultrasound Of The Sovraortic Arteries: The Potential Role In Monitoring Disease Activity and Response To Treatment In Large Vessel Vasculitis
Giuseppe Germanò¹, Pierluigi Macchioni¹, Niccolò Possemato² and Carlo Salvarani³, ¹Rheumatology Service, Arcispedale S Maria Nuova, IRCCS, Reggio Emilia, Italy, ²S.C. Reumatologia, Arcispedale Santa Maria Nuova, I.R.C.C.S., Reggio Emilia, Italy, ³Rheumatology, Arcispedale S Maria Nuova-IRCCS, Reggio Emilia, Italy
Background/Purpose: promising data has been recently published about the role of contrast-enhanced ultrasound (CEU) in the diagnosis and follow up of Takayasu arteritis (TA) -1,2-…
Abstract Number: 2360 • 2012 ACR/ARHP Annual Meeting
Prevalence, Management and Outcomes of PET Positive Large Vessel Vasculitis in Difficult to Treat PMR and GCA Patients
Pravin Patil¹, Shaifali Jain², Katerina Achilleos³, Tochukwu Adizie¹, Mark Williams¹, Matthew Tam² and Bhaskar Dasgupta⁴, ¹Rheumatology, Southend University Hospital, Westcliff on sea, United Kingdom, ²Radiology, Southend University Hospital, Westcliff on sea, United Kingdom, ³Rheumatology, Southend University Hospital, Westcliff-on-sea, United Kingdom, ⁴Rheumatology, Southend University Hospital, Westcliff-on-Sea, United Kingdom
Background/Purpose: Management of PMR and GCA can be challenging in patients with persistently elevated inflammatory markers, prominent constitutional symptoms and inadequate steroid response. We undertook…
Abstract Number: 131 • 2012 ACR/ARHP Annual Meeting
Subclinical Arthritis Visualised by Positron Emission Tomography and Macrophage Targeting Precedes Clinical Flare in Rheumatoid Arthritis Patients in DAS28 Remission
Y.Y.J. Gent¹, A.E. Voskuyl¹, N. Ahmadi², N. Hoetjes³ and C.J. van der Laken¹, ¹Rheumatology, VU University Medical Center, Amsterdam, Netherlands, ²Radiology, VU University Medical Center, Amsterdam, Netherlands, ³Nuclear Medicine & PET research, VU University Medical Center, Amsterdam, Netherlands
Background/Purpose: Macrophages play an important role in the pathophysiology of Rheumatoid Arthritis (RA). Targeting of macrophages by (R)-[11C]PK11195 positron emission tomography (PET) has previously been successfully…

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