Abstracts tagged "Periodontitis"

Abstract Number: 2414 • 2013 ACR/ARHP Annual Meeting
Elevated Serum Resistin Levels In Rheumatoid Arthritis With Periodontitis
Byoong Yong Choi¹, Jin-Hee Kim², Kyung Hwa Kim², Kyong Rok Kim³, Sang Hyun Joo⁴, Myeong Jae Yoon³, Hye Jin Oh⁵, Hye Won Kim³, Sung Hae Chang⁶, Eun Young Lee³, Eun Bong Lee⁷, Yong-Moo Lee² and Yeong Wook Song³, ¹Division of Rheumatology, Department of Internal Medicine, Seoul Medical Center, Seoul, South Korea, Seoul, South Korea, ²Department of Periodontology, School of Dentistry, Seoul National University, Seoul, South Korea, ³Division of Rheumatology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea, ⁴Division of Rheumatology, Department of Internal Medicine, Seoul National University, Seoul, South Korea, ⁵Seoul National University, Seoul, South Korea, ⁶Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea, ⁷Division of Rheumatology, Department of Internal Medicine,, Seoul National University College of Medicine, Seoul, South Korea
Background/Purpose: Epidemiological relationships between rheumatoid arthritis (RA) and periodontitis (PD) have been revealed recently. However, the pathologic link between RA and periodontitis has remained unclear.…
Abstract Number: 2417 • 2013 ACR/ARHP Annual Meeting
Antibodies To Porphyromonas Gingivalis Peptidylarginine Deiminase In Rheumatoid Arthritis Are Not Directed Against The Autocitrullinated Enzyme
Maximilian F. Konig¹, Alizay Paracha², Malini Moni¹, Clifton O. Bingham III¹ and Felipe Andrade¹, ¹Division of Rheumatology, Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, ²The University of Oklahoma, Norman, OK
Background/Purpose: Porphyromonas gingivalis (Pg) has received considerable attention by investigators trying to explain the striking association of periodontal disease (PD) and rheumatoid arthritis (RA). Bacterial…
Abstract Number: 2422 • 2013 ACR/ARHP Annual Meeting
Anti-P. Gingivalis antibody Is Correlated With Severity Of Periodontitis But Not With Rheumatoid Arthritis Disease Activity In RA
Joo Youn Lee¹, In Ah Choi², Jin-Hee Kim³, Kyung-Hwa Kim⁴, Hye Jin Oh⁵, Myeong Jae Yoon⁶, Eun Young Lee², Eun Bong Lee², Yong-Moo Lee³ and Young Wook Song^1,2, ¹Department of Molecular Medicine and Biopharmaceutical Sciences, Seoul National University, Seoul, South Korea, ²Division of Rheumatology, Department of Internal Medicine, Seoul National University, Seoul, South Korea, ³Department of Periodontology, School of Dentistry, Seoul National University, Seoul, South Korea, ⁴Department of Periodontology and Dental Research Institute, School of Dentistry, Seoul National University, Seoul, South Korea, ⁵Seoul National University, Seoul, South Korea, ⁶Division of Rheumatology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea
Background/Purpose: Periodontitis (PD) has been suggested to be one of risk factors for rheumatoid arthritis (RA). Porphyromonas gingivalis (P. ginvivalis, Pg) is a gram-negative anaerobic…
Abstract Number: 2233 • 2013 ACR/ARHP Annual Meeting
Porphyromonas Gingivalis peptidylarginine Deiminase Exacerbates Collagen-Induced Arthritis In C57BL/6 mice
Saba Alzabin^1,2, Anne-Marie Quirke², Elena B. Lugli², Muslima Choudhury^2,3, Peter J. Charles⁴, Richard O. Williams⁵ and Patrick Venables⁶, ¹Epistem Ltd., Manchester, United Kingdom, ²University of Oxford, Kennedy Institute of Rheumatology, Oxford, United Kingdom, ³Kennedy Institute of Rheumatology, London, United Kingdom, ⁴Oxford University, Kennedy Institute of Rheumatology, Oxford, United Kingdom, ⁵Kennedy Institute of Rheumatology, Oxford University, Oxford, United Kingdom, ⁶Kennedy Institute of Rheumatology, Oxford, United Kingdom
Background/Purpose: There is increasing molecular and epidemiological evidence linking Porphyromonas gingivalis to RA. P. gingivalis is unique amongst periodontal pathogens in possessing a citrullinating enzyme…
Abstract Number: 2217 • 2013 ACR/ARHP Annual Meeting
Experimental Arthritis Exacerbates Periodontal Disease But Periodontal Infection Does Not Exacerbated Experimental Arthritis
John Butcher¹, Jessica Oliver-Bell¹, Robert Benson¹, James Brewer², Paul Garside¹, Iain B. McInnes¹ and Shauna Culshaw³, ¹Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom, ²Immunology, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom, ³Dental School, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom
Background/Purpose: There is a proposed link between periodontal disease (PD) and rheumatoid arthritis (RA). A substantial, although not unanimous, body of epidemiological evidence indicates a…
Abstract Number: 1378 • 2013 ACR/ARHP Annual Meeting
Associations Of Periodontitis (PD) With Established Seropositive Rheumatoid Arthritis are Independent of Smoking and Other Risk Factors
Ted R. Mikuls¹, Jeffrey Payne², Fang Yu³, Geoffrey M. Thiele⁴, Richard J. Reynolds⁵, Grant W. Cannon⁶, Jeffrey Markt⁷, David McGowan⁸, Gail S. Kerr⁹, Robert Redman¹⁰, Andreas M. Reimold¹¹, Garth Griffiths¹², Mark Beatty², Shawneen Gonzalez², Debra Bergman¹³, Bartlett C. Hamilton III¹⁴, Alan R. Erickson¹ and James R. O'Dell¹⁵, ¹Omaha VA Medical Center and University of Nebraska Medical Center, Omaha, NE, ²College of Dentistry, University of Nebraska Medical Center, Lincoln, NE, ³University of Nebraska Medical Center, Omaha, NE, ⁴Int Med/Sec of Rheum/Immun, Univ of Nebraska Med Ctr, Omaha, NE, ⁵Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ⁶Division of Rheumatology, Salt Lake City VA and University of Utah, Salt Lake City, UT, ⁷Otol-Head and Neck Surgery, University of Nebraska Medical Center, Omaha, NE, ⁸Dentistry, George E. Wahlen VA Medical Center, Salt Lake City, UT, ⁹Rheumatology, Washington DC VAMC, Georgetown and Howard University, Washington, DC, ¹⁰Dentistry, Washington DC VA, Georgetown and Howard University, Washington, DC, ¹¹Rheumatology, Dallas VA and University of Texas Southwestern, Dallas, TX, ¹²Dentistry, Dallas VA and University of Texas Southwestern, Dallas, TX, ¹³Internal Medicine, University of Nebraska Medical Center, Omaha, NE, ¹⁴University of Nebraska Medical Center and Omaha VA Medical Center, Omaha, NE, ¹⁵Dept of Internal Medicine, University of Nebraska Medical Center, Omaha, NE
Background/Purpose: Periodontitis (PD) has been proposed as a risk factor in RA. Reports have suggested that this association may be due to confounding from smoking…
Abstract Number: 1360 • 2013 ACR/ARHP Annual Meeting
Evaluation Of Biomarkers Involved In Periondontal Disease Including Porphyromonas Gingivalis Antibodies To Predict Response To Infliximab In Rheumatoid Arthritis Patients
Mélanie Rinaudo-Gaujous¹, Pierre Miossec², Vincent Blasco-Baque³, Philippe Gaudin⁴, Christian Genin¹, Thierry Thomas⁵, Stéphane Paul¹ and Hubert Marotte⁶, ¹Laboratory of Immunology and immunomonitoring, CIC CIE3 Inserm Vaccinology, GIMAP EA3064, Hôpital Nord, Saint-Etienne, France, ²Department of Clinical Immunology and Rheumatology, Immunogenomics and inflammation research unit, Lyon, France, ³Institute of Cardiovascular and Metabolic Diseases, CHU Rangueil, Toulouse, France, ⁴Rheumatology Department, CHU Hôpital Sud, Grenoble Teaching Hospital, Echirolles, France, ⁵INSERM U1059 and University Hospital, Saint-Etienne, France, ⁶LBTO INSERM U1059 University Jean Monnet, Saint-Etienne, France
Background/Purpose: This study evaluates biological markers of rheumatoid arthritis (RA) severity including matrix metalloproteinase 3 (MMP-3) and Porphyromonas gingivalis (P. gingivalis) serology during infliximab therapy…
Abstract Number: 812 • 2013 ACR/ARHP Annual Meeting
Alveolar Bone Loss Is Associated With Disease Activity and ACPA Expression In Rheumatoid Arthritis
Ted R. Mikuls¹, Jeffrey Payne², Fang Yu³, Geoffrey M. Thiele⁴, Shawneen Gonzalez², Jeffrey Markt⁵, Jeremy Sokolove⁶, William H. Robinson⁷, Richard J. Reynolds⁸, Grant W. Cannon⁹, David McGowan¹⁰, Gail S. Kerr¹¹, Robert Redman¹², Andreas M. Reimold¹³, Garth Griffiths¹⁴, Mark Beatty², Marian Schmid², Paul Johnson², Debra Bergman¹⁵, Bartlett C. Hamilton III¹⁶, Alan R. Erickson¹ and James R. O'Dell¹⁷, ¹Omaha VA Medical Center and University of Nebraska Medical Center, Omaha, NE, ²College of Dentistry, University of Nebraska Medical Center, Lincoln, NE, ³University of Nebraska Medical Center, Omaha, NE, ⁴Int Med/Sec of Rheum/Immun, Univ of Nebraska Med Ctr, Omaha, NE, ⁵Otol-Head and Neck Surgery, University of Nebraska Medical Center, Omaha, NE, ⁶Stanford University, Palo Alto, CA, ⁷Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA, ⁸Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ⁹Division of Rheumatology, Salt Lake City VA and University of Utah, Salt Lake City, UT, ¹⁰Dentistry, George E. Wahlen VA Medical Center, Salt Lake City, UT, ¹¹Rheumatology, Washington DC VAMC, Georgetown and Howard University, Washington, DC, ¹²Dentistry, Washington DC VA, Georgetown and Howard University, Washington, DC, ¹³Rheumatology, Dallas VA and University of Texas Southwestern, Dallas, TX, ¹⁴Dentistry, Dallas VA and University of Texas Southwestern, Dallas, TX, ¹⁵Internal Medicine, University of Nebraska Medical Center, Omaha, NE, ¹⁶University of Nebraska Medical Center and Omaha VA Medical Center, Omaha, NE, ¹⁷Dept of Internal Medicine, University of Nebraska Medical Center, Omaha, NE
Background/Purpose: Periodontitis (PD) has been implicated in rheumatoid arthritis (RA) pathogenesis including the expression of anti-citrullinated protein antibody (ACPA). ACPA, in turn, have been shown…
Abstract Number: 517 • 2013 ACR/ARHP Annual Meeting
Antibody Responses To Oral Bacteria In Patients With Primary Sjögren’s Syndrome and Comparison With Rheumatoid Arthritis and Periodontitis
Bozo Lugonja¹, Michael Milward², Diana Pearson³, Thomas Dietrich⁴, Iain Chapple⁵, John Hamburger⁶, Francesca Barone¹, Saaeha Rauz⁷, Lorraine Yeo⁸, Ana Povedo-Gallego⁹, Geraint Williams⁷, Paola de Pablo¹, Andrea Richards⁹, Christopher D. Buckley¹, Dagmar Scheel-Toellner⁸ and Simon J. Bowman¹⁰, ¹Rheumatology Research Group, University of Birmingham Research Laboratories, University of Birmingham, Birmingham, United Kingdom, ²Dept of Periodontology, University of Birmingham, Birmingham, United Kingdom, ³Dept of Periodontology, Birmingham Dental Hospital, Birmingham, United Kingdom, ⁴School of Dentistry, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom, ⁵Periodontology Dept, School of Dentistry, University of Birmingham, Birmingham, United Kingdom, ⁶Dept of Oral Medicine, School of Dentistry, University of Birmingham, Birmingham, United Kingdom, ⁷Academic Unit of Ophthalmology, University of Birmingham, Birmingham, United Kingdom, ⁸Rheumatology Research Group, Centre for Translational Inflammation Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, UK, Birmingham, United Kingdom, ⁹Dept of Oral Medicine, Birmingham Dental Hospital, Birmingham, United Kingdom, ¹⁰Department of Rheumatology, Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom
Background/Purpose: We set out to examine peripheral blood antibody ELISA responses to common oral bacteria in primary Sjögren’s syndrome (pSS) to identify potential bacterial triggers…
Abstract Number: 115 • 2013 ACR/ARHP Annual Meeting
Association Between History Of Periodontitis and Risk Of Rheumatoid Arthritis In Individuals With and Without Diabetes Mellitus: A Population-Based Cohort Study
Hsin-Hua Chen^1,2, D.Y. Chen¹ and Nicole Huang³, ¹Division of Allergy, Immunology and Rheumatology, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan, ²nstitute of Public Health and Community Medicine Research Center, National Yang-Ming University, Taipei, Taiwan, ³Institute of Hospital and Health Care Administration, National Yang-Ming University, Taipei, Taiwan
Background/Purpose: To examine whether the association between periodontitis (PD) history and the rheumatoid arthritis (RA) risk differs between individuals with and without diabetes mellitus (DM).Methods:…

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