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Abstracts tagged "Periodontitis"

  • Abstract Number: 1197 • ACR Convergence 2021

    Periodontal Status Before Diagnosis in Patients with Rheumatoid Arthritis Predicts Cumulative Disease Activity in Years After Treatment Inititation

    Adelina Plachokova1, Jill Hadisurya1, Julia van Bergen2 and Rogier Thurlings3, 1Radboudumc, department of Dentistry (Implantology & Periodontology), Nijmegen, Netherlands, 2Radboudumc, department of Dentistry (Implantology & Periodontology), Nijmegen, 3Radboud University Medical Centre, Nijmegen, Netherlands

    Background/Purpose: Transversal cohort studies demonstrated a possible association between periodontal disease (PD) and rheumatoid arthritis (RA). However it is unknown how this association evolves during…
  • Abstract Number: 42 • 2019 ACR/ARP Annual Meeting

    Subclinical Oral Inflammation Is Common Across the Spectrum of Oral Findings in Rheumatoid Arthritis Patients, Whereas Porphyromonas Gingivalis Antibodies Are Primarily a Marker for Clinical Periodontitis

    Sheila Arvikar1, Hatice Hasturk 2, Klemen Strle 1, Marcy Bolster 1, Deborah Collier 1, Alpdogan Kantarci 2 and Allen Steere 1, 1Massachusetts General Hospital, Boston, MA, 2Forsyth, Cambridge, MA

    Background/Purpose: Periodontitis and immune responses to periodontal pathogens such as Porphyromonas gingivalis (Pg) are associated with rheumatoid arthritis (RA) but the mechanisms underlying these connections…
  • Abstract Number: 2061 • 2019 ACR/ARP Annual Meeting

    Association of Periodontitis with Rheumatological Disorders: NHANES III Analysis

    Vivekanand Tiwari1, Lawrence Brent 1, Jasim Albandar 2, Chinhua Hsiao 2 and Shikha Shah 3, 1Temple University, Philadelphia, PA, 2Kornberg School of Dentistry, Temple University, Philadelphia, PA, 3Levy Center for Oral Health Research, Philadelphia, PA

    Background/Purpose: The association between periodontal diseases, smoking, and some systemic diseases such as diabetes mellitusis is well established. Periodontitis and rheumatological disorders share common immunological features and…
  • Abstract Number: 79 • 2018 ACR/ARHP Annual Meeting

    Rheumatoid Arthritis (RA)-Associated Autoantibodies Are Present in the Periodontal Exudate of Patients with and without RA

    Poerwati Soetji Rahajoe1, Menke J. de Smit2, Elisabeth Eelsing2, Nyoman Kertia3, Arjan Vissink4 and Johanna Westra2, 1Oral Surgery, Dr. Sardjito General Hospital, Yogyakarta, Indonesia, 2Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, 3Rheumatology, Dr. Sardjito General Hospital, Yogyakarta, Indonesia, 4Department of Oral and Maxillofacial Surgery, University of Groningen, University Medical Center Groningen, Groningen, Netherlands

    Background/Purpose: Seropositivity for anti-citrullinated protein antibodies (ACPA) and rheumatoid factor (RF) is a hallmark of RA and can be present years before clinical onset has…
  • Abstract Number: 567 • 2018 ACR/ARHP Annual Meeting

    Non-Surgical Periodontal Therapy Plus Short-Term Antibiotic Treatment May Improve Clinical Disease Activity: A Pilot Study in Difficult to Treat Rheumatoid Arthritis

    Burkhard Moeller1, Philip Bender2, Sigrun Eick2, Kim Midwood3, Jan Potempa4, Stephan Reichenbach5, Anja Schwenzer3, Peter M. Villiger6 and Alicia Wong3, 1Rheumatology, Immunology and Allergology, Inselspital, University Hospital of Bern, Bern, Switzerland, 2School of Dental Medicine, University of Bern, Bern, Switzerland, 3Kennedy Institute for Rheumatology, Oxford University, Oxford, United Kingdom, 4Department of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland, 5Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland, 6University of Bern, Bern, Switzerland

    Background/Purpose: Autoimmunity against citrullinated peptides is a hallmark of rheumatoid arthritis (RA). Chronic periodontitis (CP) is a known major source of citrullinated peptides. Here, we…
  • Abstract Number: 2540 • 2018 ACR/ARHP Annual Meeting

    Effect of Buccal Hygiene on the Systemic Activity of Patients with Rheumatoid Arthritis: A Randomized Clinical Trial

    Xavier Mariette1, Elodie Perrodeau2, Christian Verner3, Xavier Struillou4, Thierry Schaeverbeke5, Alain Cantagrel6, Philippe Ravaud7 and Philippe Bouchard8, 1Rheumatology, Université Paris Sud, Le Kremlin Bicêtre, France, 2Paris Hotel Dieu, Paris, France, 3Periodontology, UFR d'odontologie, University of Nantes, Nantes, France, 4Periodontology, UFR d'odontologie, University of Nantes,, Nantes, France, 5Rheumatology, CHU Bordeaux, Bordeaux, France, 6Rheumatology, CHU Toulouse, Toulouse, France, 7INSERM UMR1153, Paris Descartes University, Paris, France, 8Paris Diderot University, Paris, France

    Background/Purpose: Good evidence suggests a relationship between rheumatoid arthritis (RA) and periodontitis. We aimed to investigate if a good oral hygiene could improve activity of…
  • Abstract Number: 2793 • 2018 ACR/ARHP Annual Meeting

    Molecular Mimicry and Autoimmunity: Anti-P. Gingivalis antibody Response in ACPA-Positive Rheumatoid Arthritis

    Natalia Sherina1, Natalie Sippl1, Lena Israelsson1, Erwan Le Maitre2, Nastya Kharlamova1, Monika Hansson3, Kaja Eriksson4, Tulay Yucel-Lindberg4, Khaled Amara1 and Karin Lundberg1, 1Rheumatology Unit, Department of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden, 2Rheumatology Unit, Department of Medicine, Solna,, Karolinska Institutet, Stockholm, Sweden, 3Medicine, Rheumatology Unit, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden, 4Division of Periodontology, Department of Dental Medicine, Karolinska Institutet, Stockholm, Sweden

    Background/Purpose: The presence of anti-citrullinated protein antibodies (ACPA) is a hallmark of rheumatoid arthritis (RA). ACPAs specifically recognize citrullinated epitopes, a result of a post-translational…
  • Abstract Number: 2913 • 2017 ACR/ARHP Annual Meeting

    the Periodontal Pathogen Aggregatibacter Actinomycetemcomitans Is Associated with Subclinical Coronary Atherosclerosis in Rheumatoid Arthritis

    Jon T. Giles1, Jesper Reinholdt2, Joan Bathon3, Felipe Andrade4 and Maximilian F. Konig5, 1Division of Rheumatology, Columbia University, College of Physicians and Surgeons, New York, NY, 2Department of Biomedicine, Aarhus University, Aarhus, Denmark, 3Division of Rheumatology, Columbia University, College of Physicians & Surgeons, New York, NY, 4Medicine/Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, 5Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA

    Background/Purpose: The oral pathogen Aggregatibacter actinomycetemcomitans (Aa) generates citrullinated proteins targeted by autoantibodies in RA through its pore-forming toxin leukotoxin A (LtxA).  Aa-derived LtxA is…
  • Abstract Number: 492 • 2017 ACR/ARHP Annual Meeting

    Is Leukotoxin_A Produced By Aggregatibacter Actynomycetemcomitans Important for Initiating Autoimmune Responses Underlying Rheumatoid Arthritis?

    Mikhail Volkov1, Jacqueline Dekkers1, Bruno G. Loos2, Sergio Bizzarro2, Tom W.J. Huizinga3, Helle A. Praetorius4, Rene E.M. Toes5 and Diane van der Woude1, 1Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Department of Periodontology, Academic Centre for Dentistry Amsterdam, University of Amsterdam and Vrije Universiteit, Amsterdam, Netherlands, 3Department of Rheumatology, LUMC, Leiden, Netherlands, Leiden, Netherlands, 4Department of Biomedicine, Aarhus University, Aarhus, Denmark, 5Rheumatology, Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose: In a recent publication in Science Translational Medicine, Konig et al. (2016) describe a potential explanation for the link between periodontal infection and RA.…
  • Abstract Number: 494 • 2017 ACR/ARHP Annual Meeting

    The Oral Microbiome Is Altered in Patients with Rheumatoid Arthritis

    Sheila Arvikar1, Hatice Hasturk2, Klemen Strle3, Daniel Nguyen4, Marcy B. Bolster5, Deborah Collier6, Alpdogan Kantarci2 and Allen Steere1, 1Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, BOSTON, MA, 2Department of Applied Oral Health Sciences, Forsyth, Cambridge, MA, 3Department of Immunology and Inflammatory Diseases, Massachusetts General Hospital, BOSTON, MA, 4Forsyth, Cambridge, MA, 5Rheumatology, Allergy and Immunology, Endocrine Associates, Massachusetts General Hospital, Boston, MA, 6Rheumatology, Massachusetts General Hospital, Boston, MA

    Background/Purpose: The mouth is the second most abundantly colonized mucosal surface in the human body. Periodontitis, a polymicrobial infectious and inflammatory disease of tooth-supporting structures,…
  • Abstract Number: 640 • 2017 ACR/ARHP Annual Meeting

    Is There a Relationship between Spondyloarthritis and Periodontitis? a Case-Control Study

    Wilson Bautista-Molano1, Désirée van der Heijde2, Robert B.M. Landewé3, Gloria Lafaurie4, Julieth De Avila4, Rafael Valle-Oñate5 and Consuelo Romero-Sanchez6, 1School of Medicine, Universidad Militar Nueva Granada and Rheumatology Department Hospital Militar, Colombia, Bogotá, Colombia, 2Leiden University Medical Center, Leiden, Netherlands, 3University of Amsterdam and Atrium Medical Center, Amsterdam, Netherlands, 4Unit of Oral Basic Investigation-UIBO, School of Dentistry, Universidad El Bosque, Colombia, Bogotá, Colombia, 5School of Medicine, Universidad Militar Nueva Granada and Rheumatology Department Hospital Militar, Colombia, Bogota, Colombia, 6Unit of Oral Basic Investigation-UIBO, School of Dentistry, Universidad El Bosque, Colombia, BOGOTA, Colombia

    Background/Purpose: Knowledge of the existence of an epidemiological association between SpA and periodontitis may fuel pathophysiological thinking about SpA and if established, have clinical implications.…
  • Abstract Number: 1331 • 2017 ACR/ARHP Annual Meeting

    A Pathogenic Role of Porphyomonas Gingivalis Fimbriae (FimA) in Periodontitis-Associated Rheumatoid Arthritis

    Ji-Won Kim1, Jennifer Lee2, Yeon-Sik Hong3, Sung-Hwan Park2 and Ji Hyeon Ju2, 1Medicine, Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of (South), 2Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of (South), 3Division of Rheumatology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of (South)

    Background/Purpose: Periodontitis induced by oral pathogen Porphyromonas gingivalis (Pg) has been suggested to be associated with rheumatoid arthritis (RA). Pg peptidyl arginine deiminase -mediated citrullination…
  • Abstract Number: 1343 • 2017 ACR/ARHP Annual Meeting

    Gingival Bleeding and Periodontitis in Japanese Patients with Rheumatoid Arthritis: Results from the IORRA Cohort Study

    Takefumi Furuya1, Eisuke Inoue2, Shigeru Maeda3, Eiichi Tanaka1, Katsunori Ikari1, Ayako Nakajima1, Atsuo Taniguchi1 and Hisashi Yamanaka1, 1Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan, 2Division of Medical Informatics, St. Marianna University School of Medicine, Kawasaki, Japan, 3Department of Dental Anesthesiology, Okayama University Hospital, Okayama, Japan

    Background/Purpose: Oral health is an important issue for patients with rheumatoid arthritis (RA) because periodontitis is a potential risk factor for RA and RA patients…
  • Abstract Number: 1383 • 2017 ACR/ARHP Annual Meeting

    IMPACT of Smoking in the Expression of Periodontitis and Anticitrullinated Protein Antibodies in Rheumatoid Arthritis

    Jerián González Febles1, Jorge Luis Garnier Rodríguez2, Fernando Sánchez-Alonso3, Sagrario Bustabad4, Federico Díaz-González5, Mariano Sanz Alonso1 and Beatriz Rodriguez Lozano6, 1Periodontology, Universidad Complutense de Madrid, Madrid, Spain, 2Odontology, Dental Clinic Garnier, S/C Tenerife, Spain, 3Unidad de Investigación, Spanish Society of Rheumatology, Madrid, Spain, 4Rheumatology, Servicio de Reumatología. Hospital Universitario de Canarias, La Laguna, Tenerife, Spain, 5Servicio de Reumatología. Hospital Universitario de Canarias, Santa Cruz de Tenerife, Spain, 6Rheumatology, Hospital de Canarias, S/C Tenerife, Spain

    Background/Purpose: Environmental, genetic and epigenetic factors can induce citrullination of structural peptides by the enzyme PAD, which induce anti-citrullinated protein antibodies (ACPA) preceding RA. Among…
  • Abstract Number: 507 • 2016 ACR/ARHP Annual Meeting

    Comparison of Body Mass Index, Anti-Citrullinated Peptides Antibodies Status and Periodontal Condition in First Degree Relatives Individuals to Rheumatoid Arthritis

    Sonia Unriza-Puin1, Wilson Bautista-Molano2,3, Gloria Lafaurie4, Rafael R. Valle-Oñate5, Phillipe Chalem6, Lorena Chila3, Juan Manuel Bello7 and Consuelo Romero Sanchez3,8, 1Unit of Oral Basic Investigation, School of Dentistry, Universidad El Bosque, Bogota, Colombia, 2Rheumatology Department School of Medicine HMC / UMNG, Bogotá, Colombia, 3Unit of Oral Basic Investigation, School of Dentistry, Universidad El Bosque, Bogotá, Colombia, 4Unit of Oral Basic Investigation-UIBO, School of Dentistry, Universidad El Bosque, Bogotá, Colombia, 5Rheumatology, Rheumatology Department School of Medicine HMC / UMNG, Bogota, Colombia, 6Fundación Instituto de Reumatología Fernando Chalem, Bogotá, Colombia, 7Rheumatology Department School of Medicine HMC / UMNG, Bogota, Colombia, 8Rheumatology, School of Medicine HMC / UMNG, Bogota, Colombia

    Background/Purpose:  Association studies in rheumatoid arthritis (RA) have been focused in the pre-clinical phases of the disease in asymptomatic individuals with higher risk to develop…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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