Abstracts tagged "Periodontitis"

Abstract Number: 1197 • ACR Convergence 2021
Periodontal Status Before Diagnosis in Patients with Rheumatoid Arthritis Predicts Cumulative Disease Activity in Years After Treatment Inititation
Adelina Plachokova¹, Jill Hadisurya¹, Julia van Bergen² and Rogier Thurlings³, ¹Radboudumc, department of Dentistry (Implantology & Periodontology), Nijmegen, Netherlands, ²Radboudumc, department of Dentistry (Implantology & Periodontology), Nijmegen, ³Radboud University Medical Centre, Nijmegen, Netherlands
Background/Purpose: Transversal cohort studies demonstrated a possible association between periodontal disease (PD) and rheumatoid arthritis (RA). However it is unknown how this association evolves during…
Abstract Number: 42 • 2019 ACR/ARP Annual Meeting
Subclinical Oral Inflammation Is Common Across the Spectrum of Oral Findings in Rheumatoid Arthritis Patients, Whereas Porphyromonas Gingivalis Antibodies Are Primarily a Marker for Clinical Periodontitis
Sheila Arvikar¹, Hatice Hasturk ², Klemen Strle ¹, Marcy Bolster ¹, Deborah Collier ¹, Alpdogan Kantarci ² and Allen Steere ¹, ¹Massachusetts General Hospital, Boston, MA, ²Forsyth, Cambridge, MA
Background/Purpose: Periodontitis and immune responses to periodontal pathogens such as Porphyromonas gingivalis (Pg) are associated with rheumatoid arthritis (RA) but the mechanisms underlying these connections…
Abstract Number: 2061 • 2019 ACR/ARP Annual Meeting
Association of Periodontitis with Rheumatological Disorders: NHANES III Analysis
Vivekanand Tiwari¹, Lawrence Brent ¹, Jasim Albandar ², Chinhua Hsiao ² and Shikha Shah ³, ¹Temple University, Philadelphia, PA, ²Kornberg School of Dentistry, Temple University, Philadelphia, PA, ³Levy Center for Oral Health Research, Philadelphia, PA
Background/Purpose: The association between periodontal diseases, smoking, and some systemic diseases such as diabetes mellitusis is well established. Periodontitis and rheumatological disorders share common immunological features and…
Abstract Number: 79 • 2018 ACR/ARHP Annual Meeting
Rheumatoid Arthritis (RA)-Associated Autoantibodies Are Present in the Periodontal Exudate of Patients with and without RA
Poerwati Soetji Rahajoe¹, Menke J. de Smit², Elisabeth Eelsing², Nyoman Kertia³, Arjan Vissink⁴ and Johanna Westra², ¹Oral Surgery, Dr. Sardjito General Hospital, Yogyakarta, Indonesia, ²Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, ³Rheumatology, Dr. Sardjito General Hospital, Yogyakarta, Indonesia, ⁴Department of Oral and Maxillofacial Surgery, University of Groningen, University Medical Center Groningen, Groningen, Netherlands
Background/Purpose: Seropositivity for anti-citrullinated protein antibodies (ACPA) and rheumatoid factor (RF) is a hallmark of RA and can be present years before clinical onset has…
Abstract Number: 567 • 2018 ACR/ARHP Annual Meeting
Non-Surgical Periodontal Therapy Plus Short-Term Antibiotic Treatment May Improve Clinical Disease Activity: A Pilot Study in Difficult to Treat Rheumatoid Arthritis
Burkhard Moeller¹, Philip Bender², Sigrun Eick², Kim Midwood³, Jan Potempa⁴, Stephan Reichenbach⁵, Anja Schwenzer³, Peter M. Villiger⁶ and Alicia Wong³, ¹Rheumatology, Immunology and Allergology, Inselspital, University Hospital of Bern, Bern, Switzerland, ²School of Dental Medicine, University of Bern, Bern, Switzerland, ³Kennedy Institute for Rheumatology, Oxford University, Oxford, United Kingdom, ⁴Department of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland, ⁵Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland, ⁶University of Bern, Bern, Switzerland
Background/Purpose: Autoimmunity against citrullinated peptides is a hallmark of rheumatoid arthritis (RA). Chronic periodontitis (CP) is a known major source of citrullinated peptides. Here, we…
Abstract Number: 2540 • 2018 ACR/ARHP Annual Meeting
Effect of Buccal Hygiene on the Systemic Activity of Patients with Rheumatoid Arthritis: A Randomized Clinical Trial
Xavier Mariette¹, Elodie Perrodeau², Christian Verner³, Xavier Struillou⁴, Thierry Schaeverbeke⁵, Alain Cantagrel⁶, Philippe Ravaud⁷ and Philippe Bouchard⁸, ¹Rheumatology, Université Paris Sud, Le Kremlin Bicêtre, France, ²Paris Hotel Dieu, Paris, France, ³Periodontology, UFR d'odontologie, University of Nantes, Nantes, France, ⁴Periodontology, UFR d'odontologie, University of Nantes,, Nantes, France, ⁵Rheumatology, CHU Bordeaux, Bordeaux, France, ⁶Rheumatology, CHU Toulouse, Toulouse, France, ⁷INSERM UMR1153, Paris Descartes University, Paris, France, ⁸Paris Diderot University, Paris, France
Background/Purpose: Good evidence suggests a relationship between rheumatoid arthritis (RA) and periodontitis. We aimed to investigate if a good oral hygiene could improve activity of…
Abstract Number: 2793 • 2018 ACR/ARHP Annual Meeting
Molecular Mimicry and Autoimmunity: Anti-P. Gingivalis antibody Response in ACPA-Positive Rheumatoid Arthritis
Natalia Sherina¹, Natalie Sippl¹, Lena Israelsson¹, Erwan Le Maitre², Nastya Kharlamova¹, Monika Hansson³, Kaja Eriksson⁴, Tulay Yucel-Lindberg⁴, Khaled Amara¹ and Karin Lundberg¹, ¹Rheumatology Unit, Department of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden, ²Rheumatology Unit, Department of Medicine, Solna,, Karolinska Institutet, Stockholm, Sweden, ³Medicine, Rheumatology Unit, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden, ⁴Division of Periodontology, Department of Dental Medicine, Karolinska Institutet, Stockholm, Sweden
Background/Purpose: The presence of anti-citrullinated protein antibodies (ACPA) is a hallmark of rheumatoid arthritis (RA). ACPAs specifically recognize citrullinated epitopes, a result of a post-translational…
Abstract Number: 492 • 2017 ACR/ARHP Annual Meeting
Is Leukotoxin_A Produced By Aggregatibacter Actynomycetemcomitans Important for Initiating Autoimmune Responses Underlying Rheumatoid Arthritis?
Mikhail Volkov¹, Jacqueline Dekkers¹, Bruno G. Loos², Sergio Bizzarro², Tom W.J. Huizinga³, Helle A. Praetorius⁴, Rene E.M. Toes⁵ and Diane van der Woude¹, ¹Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Department of Periodontology, Academic Centre for Dentistry Amsterdam, University of Amsterdam and Vrije Universiteit, Amsterdam, Netherlands, ³Department of Rheumatology, LUMC, Leiden, Netherlands, Leiden, Netherlands, ⁴Department of Biomedicine, Aarhus University, Aarhus, Denmark, ⁵Rheumatology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: In a recent publication in Science Translational Medicine, Konig et al. (2016) describe a potential explanation for the link between periodontal infection and RA.…
Abstract Number: 494 • 2017 ACR/ARHP Annual Meeting
The Oral Microbiome Is Altered in Patients with Rheumatoid Arthritis
Sheila Arvikar¹, Hatice Hasturk², Klemen Strle³, Daniel Nguyen⁴, Marcy B. Bolster⁵, Deborah Collier⁶, Alpdogan Kantarci² and Allen Steere¹, ¹Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, BOSTON, MA, ²Department of Applied Oral Health Sciences, Forsyth, Cambridge, MA, ³Department of Immunology and Inflammatory Diseases, Massachusetts General Hospital, BOSTON, MA, ⁴Forsyth, Cambridge, MA, ⁵Rheumatology, Allergy and Immunology, Endocrine Associates, Massachusetts General Hospital, Boston, MA, ⁶Rheumatology, Massachusetts General Hospital, Boston, MA
Background/Purpose: The mouth is the second most abundantly colonized mucosal surface in the human body. Periodontitis, a polymicrobial infectious and inflammatory disease of tooth-supporting structures,…
Abstract Number: 640 • 2017 ACR/ARHP Annual Meeting
Is There a Relationship between Spondyloarthritis and Periodontitis? a Case-Control Study
Wilson Bautista-Molano¹, Désirée van der Heijde², Robert B.M. Landewé³, Gloria Lafaurie⁴, Julieth De Avila⁴, Rafael Valle-Oñate⁵ and Consuelo Romero-Sanchez⁶, ¹School of Medicine, Universidad Militar Nueva Granada and Rheumatology Department Hospital Militar, Colombia, Bogotá, Colombia, ²Leiden University Medical Center, Leiden, Netherlands, ³University of Amsterdam and Atrium Medical Center, Amsterdam, Netherlands, ⁴Unit of Oral Basic Investigation-UIBO, School of Dentistry, Universidad El Bosque, Colombia, Bogotá, Colombia, ⁵School of Medicine, Universidad Militar Nueva Granada and Rheumatology Department Hospital Militar, Colombia, Bogota, Colombia, ⁶Unit of Oral Basic Investigation-UIBO, School of Dentistry, Universidad El Bosque, Colombia, BOGOTA, Colombia
Background/Purpose: Knowledge of the existence of an epidemiological association between SpA and periodontitis may fuel pathophysiological thinking about SpA and if established, have clinical implications.…
Abstract Number: 1331 • 2017 ACR/ARHP Annual Meeting
A Pathogenic Role of Porphyomonas Gingivalis Fimbriae (FimA) in Periodontitis-Associated Rheumatoid Arthritis
Ji-Won Kim¹, Jennifer Lee², Yeon-Sik Hong³, Sung-Hwan Park² and Ji Hyeon Ju², ¹Medicine, Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of (South), ²Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of (South), ³Division of Rheumatology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of (South)
Background/Purpose: Periodontitis induced by oral pathogen Porphyromonas gingivalis (Pg) has been suggested to be associated with rheumatoid arthritis (RA). Pg peptidyl arginine deiminase -mediated citrullination…
Abstract Number: 1343 • 2017 ACR/ARHP Annual Meeting
Gingival Bleeding and Periodontitis in Japanese Patients with Rheumatoid Arthritis: Results from the IORRA Cohort Study
Takefumi Furuya¹, Eisuke Inoue², Shigeru Maeda³, Eiichi Tanaka¹, Katsunori Ikari¹, Ayako Nakajima¹, Atsuo Taniguchi¹ and Hisashi Yamanaka¹, ¹Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan, ²Division of Medical Informatics, St. Marianna University School of Medicine, Kawasaki, Japan, ³Department of Dental Anesthesiology, Okayama University Hospital, Okayama, Japan
Background/Purpose: Oral health is an important issue for patients with rheumatoid arthritis (RA) because periodontitis is a potential risk factor for RA and RA patients…
Abstract Number: 1383 • 2017 ACR/ARHP Annual Meeting
IMPACT of Smoking in the Expression of Periodontitis and Anticitrullinated Protein Antibodies in Rheumatoid Arthritis
Jerián González Febles¹, Jorge Luis Garnier Rodríguez², Fernando Sánchez-Alonso³, Sagrario Bustabad⁴, Federico Díaz-González⁵, Mariano Sanz Alonso¹ and Beatriz Rodriguez Lozano⁶, ¹Periodontology, Universidad Complutense de Madrid, Madrid, Spain, ²Odontology, Dental Clinic Garnier, S/C Tenerife, Spain, ³Unidad de Investigación, Spanish Society of Rheumatology, Madrid, Spain, ⁴Rheumatology, Servicio de Reumatología. Hospital Universitario de Canarias, La Laguna, Tenerife, Spain, ⁵Servicio de Reumatología. Hospital Universitario de Canarias, Santa Cruz de Tenerife, Spain, ⁶Rheumatology, Hospital de Canarias, S/C Tenerife, Spain
Background/Purpose: Environmental, genetic and epigenetic factors can induce citrullination of structural peptides by the enzyme PAD, which induce anti-citrullinated protein antibodies (ACPA) preceding RA. Among…
Abstract Number: 2913 • 2017 ACR/ARHP Annual Meeting
the Periodontal Pathogen Aggregatibacter Actinomycetemcomitans Is Associated with Subclinical Coronary Atherosclerosis in Rheumatoid Arthritis
Jon T. Giles¹, Jesper Reinholdt², Joan Bathon³, Felipe Andrade⁴ and Maximilian F. Konig⁵, ¹Division of Rheumatology, Columbia University, College of Physicians and Surgeons, New York, NY, ²Department of Biomedicine, Aarhus University, Aarhus, Denmark, ³Division of Rheumatology, Columbia University, College of Physicians & Surgeons, New York, NY, ⁴Medicine/Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, ⁵Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA
Background/Purpose: The oral pathogen Aggregatibacter actinomycetemcomitans (Aa) generates citrullinated proteins targeted by autoantibodies in RA through its pore-forming toxin leukotoxin A (LtxA). Aa-derived LtxA is…
Abstract Number: 2559 • 2016 ACR/ARHP Annual Meeting
Subgingival Microbiome Signatures in Patients with Established Rheumatoid Arthritis and Osteoarthritis
Ted R Mikuls¹, Clay Walker², Fang Qiu³, Fang Yu⁴, Geoffrey M. Thiele⁵ and Jeffrey Payne⁶, ¹Veteran Affairs Nebraska-Western Iowa Health Care System and University of Nebraska Medical Center, Omaha, NE, ²College of Dentistry, University of Florida, Gainesville, FL, ³Biostatistics, University of Nebraska Medical Center, Omaha, NE, ⁴Public Health, University of Nebraska Medical Center, Omaha, NE, ⁵University of Nebraska Medical Center, Omaha, NE, ⁶College of Dentistry, University of Nebraska Medical Center, Lincoln, NE
Background/Purpose: Periodontitis (PD) is an inflammatory disease of tissues supporting the teeth, caused by microorganisms that adhere to and grow along the tooth’s surface. …

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