Abstracts tagged "Pediatric rheumatology"

Abstract Number: 1059 • ACR Convergence 2025
Assessing the Relationship Between Multidimensional Area Level Indicators and Lupus Disease Activity in Children
Chelsea Reynolds¹, Natasha Ruth², Paul Nietert¹, Mileka Gilbert¹, Emily Vara¹ and Joyce Chang³, ¹Medical University of South Carolina, Charleston, SC, ²Medical University South Carolina, Charleston, SC, ³Boston Children's Hospital, Boston, MA
Background/Purpose: Recent research suggests that multidimensional area-level indicators, including the Social Vulnerability Index (SVI), Area Deprivation Index (ADI) and Childhood Opportunity Index (COI), associate with…
Abstract Number: 0413 • ACR Convergence 2025
Improving Access to Timely Joint Injections for Pediatric Rheumatology Patients – A Quality Improvement Initiative
Kendra Lauer¹, Vidya Sivaraman², Melissa Argraves³, Ysabella Esteban⁴, Laura Pratt⁵, Alysha Taxter⁶, Shoghik Akoghlanian³, Kelly Wise⁷, Kathryn Anliker³, Jonnie Hughes³, James Booker³, Ashlee Leone³ and Edward Oberle³, ¹Nationwide Children's Hospital, Dublin, OH, ²Nationwide Children's Hospital/ The Ohio State University, Columbus, OH, ³Nationwide Children's Hospital, Columbus, OH, ⁴Nationwide Children's Hospital, Plain City, OH, ⁵Nationwide Children's Hospital/The Ohio State University College of Medicine, Columbus, OH, ⁶Nationwide Children's, Columbus, OH, ⁷Nationwide Children's Hospital, Hilliard, OH
Background/Purpose: Timely treatment for juvenile idiopathic arthritis (JIA) is essential for disease remission and decreasing risk of long-term morbidity. Intra-articular corticosteroid joint injections can treat…
Abstract Number: 0361 • ACR Convergence 2025
Transition in Focus: Health Care Utilization and Disease Status in Youth with Connective Tissue Diseases— A Single-Center Experience in British Columbia, Canada
Mercedes Chan¹, Lori Tucker¹, Jude AlMasoud¹, Jaime Guzman², Andrea Human¹, David Cabral³, Angela How⁴, Wendy Wong⁵ and Jennifer Corpuz⁶, ¹BC Children's Hospital, Vancouver, BC, Canada, ²University of British Columbia and BC Children's Hospital, Vancouver, BC, Canada, ³BC Children's Hospital and University of British Columbia, Vancouver, BC, Canada, ⁴UBC, Vancouver, BC, Canada, ⁵University of British Columbia, Surrey, BC, Canada, ⁶UBC, New Westminster, BC, Canada
Background/Purpose: Graduating from child and family-oriented to adult-oriented health care is a vulnerable time when youth with chronic disease drop out of, or disengage from,…
Abstract Number: 2188 • ACR Convergence 2025
Enhancing Pediatric Rheumatology Education Through Case-Based Learning: Impact on Knowledge, Confidence, and Elective Interest
Nayimisha Balmuri, Hopkins, Baltimore
Background/Purpose: Pediatric rheumatic diseases are rare and frequently under-recognized by trainees, leading to delayed diagnosis and referral. To address this gap, we developed a case-based…
Abstract Number: 2144 • ACR Convergence 2025
The Association Between Age at Diagnosis and Health-Related Quality of Life in ANCA-Associated Vasculitis
Jessica Bloom¹, Kaci Pickett-Nairne², Lori Silveira¹, Cristina Burroughs³, Katrina Bargender⁴, Amy Bolton⁴, Christine Yeung⁴, Jennifer Gordon⁵, Peter Merkel⁶ and Karen James⁷, ¹University of Colorado, Aurora, CO, ²University of Colorado, Denver, ³University of South Florida, Tampa, FL, ⁴Vasculitis Patient-Powered Research Network, Philadelphia, PA, ⁵Vasculitis Foundation, Kansas City, MO, ⁶University of Pennsylvania, Philadelphia, PA, ⁷University of Utah, Salt Lake City, UT
Background/Purpose: ANCA-associated vasculitis (AAV) is a chronic autoimmune condition that significantly impacts patients’ quality of life. It is unknown whether this impact varies based on…
Abstract Number: 1827 • ACR Convergence 2025
Transcriptomics and Machine Learning Unraveling the Molecular Drivers of PFAPA Flares
Sivia Lapidus¹, Tresa Ambooken², Ellen Hakim³, Tara Lozy⁴, Elahe Golalipour³, Sohail Adonimohammed⁵, Jennifer Weiss⁶, Suzanne Li⁶, Amanda Nowakowski⁷, Aryeh Lejtman⁸, Aaron Sebbag³, Ariel Aptekmann⁹ and Jigar Desai⁹, ¹Joseph M. Sanzari Children's Hospital, Center for Discovery and Innovation, Hackensack Meridian School of Medicine, Montclair, NJ, ²Food and Drug Administration, Floral Park, NY, ³Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ, ⁴Joseph M. Sanzari Children's Hospital, Center for Discovery and Innovation, Hackensack Meridian School of Medicine, Nutley, ⁵Hackensack Meridian School of Medicine, Nutley, NJ, ⁶Joseph M. Sanzari Children's Hospital and Hackensack Meridian School of Medicine, Hackensack, NJ, ⁷Joseph M. Sanzari Children's Hospital, Hackensack Meridian Health, Hackensack, NJ, ⁸Joseph M. Sanzari Children's Hospital and Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ, ⁹Center for Discovery and Innovation and Hackensack Meridian School of Medicine, Hackensack Meridian Health, Nutley, NJ
Background/Purpose: Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Adenitis (PFAPA) is the most common periodic fever presenting with frequent episodes of pain and impaired function. While…
Abstract Number: 1740 • ACR Convergence 2025
A New Link Between Calprotectin, Cholesterol Efflux Dysfunction, and Premature Atherosclerosis in Juvenile Dermatomyositis
Emily Chong¹, Kavya Sugur², Sophia Matossian¹, Katarina Kmetova³, Christine Goudsmit⁴, Jessica Turnier⁵ and Yu (Ray) Zuo¹, ¹University of Michigan, Ann Arbor, MI, ²Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, Ann Arbor, MI, ³Division of Rheumatology, University of Michigan, Ann Arbor, Michigan, USA, Ann Arbor, MI, ⁴University of Michigan, Ann Arbor, ⁵University of Michigan, Saline, MI
Background/Purpose: Adults with dermatomyositis face a well-established 2–3-fold increased risk of major adverse cardiovascular events, driven by systemic inflammation, endothelial dysfunction, and treatment-related metabolic complications.…
Abstract Number: 1301 • ACR Convergence 2025
Prevalence, Clinical and Genetic Risk Factors, and Time to Cataract Development in Childhood-onset Systemic Lupus Erythematosus
Sirikarn Tangcheewinsirikul¹, Zhaoyu Ding², Nicholas Chan³, Daniela Dominguez³, Andrea Knight⁴, Deborah Levy¹, Lawrence Ng⁵, Earl Silverman¹, Ruud Verstegen¹ and Linda Hiraki¹, ¹The Hospital for Sick Children, Toronto, ON, Canada, ²SickKids Research Institute, Toronto, ON, Canada, ³The Hospital for Sick Children, Toronto, Canada, ⁴Hospital for Sick Children, Toronto, ON, Canada, ⁵The Hospital for Sick Children, Toronto, Canada, Toronto, ON, Canada
Background/Purpose: Cataracts are a significant ocular complication in childhood-onset systemic lupus erythematosus (cSLE). This study aimed to assess the prevalence, time to cataract development, and…
Abstract Number: 1285 • ACR Convergence 2025
Investigating the Relationship Between Brain Injury Markers and Brain Volume in Children with Systemic Lupus Erythematosus and Healthy Controls
Ganesh Ramanathan¹, Diana Valdes Cabrera², Oscar Mwizerwa³, Justine Ledochowski², Tala El Tal⁴, Sarah Mossad⁵, Ibrahim Mohamed¹, Joanna Law⁶, Lawrence Ng⁷, Paris Moaf², Asha Jeyanathan⁶, Adrienne Davis⁶, Ann Yeh⁶, Linda Hiraki², Deborah Levy², Zahi Touma⁸, Joan Wither⁹, Busisiwe Zapparoli¹⁰, Ashley Danguecan⁵ and Andrea Knight⁵, ¹The Hospital for Sick Children, Brampton, ON, Canada, ²The Hospital for Sick Children, Toronto, ON, Canada, ³University of Toronto, The Hospital for Sick Children, Toronto, ON, Canada, ⁴Children's Hospital of Eastern Ontario (CHEO), Ottawa, ON, Canada, ⁵Hospital for Sick Children, Toronto, ON, Canada, ⁶The Hospital for Sick Children, Toronto, Canada, ⁷The Hospital for Sick Children, Toronto, Canada, Toronto, ON, Canada, ⁸University of Toronto, Toronto, ON, Canada, ⁹University Health Network, Toronto, ON, Canada, ¹⁰The Hospital for Sick Children, Etobicoke, ON, Canada
Background/Purpose: Patients with childhood-onset systemic lupus erythematosus (cSLE) are at high risk for neuropsychiatric involvement as disease onset typically occurs during the critical period of…
Abstract Number: 0993 • ACR Convergence 2025
NOD2 mutations mediate IL-17 predisposition in patients with Blau syndrome
Leah Huey¹, Emily Vance², Bryce Binstadt³ and Ruth Napier², ¹Oregon Health & Science University, Denver, CO, ²University of Colorado Anschutz, Aurora, CO, ³University of Minnesota, Minneapolis, MN
Background/Purpose: Blau syndrome is a pediatric rheumatic disease characterized by dermatitis, arthritis, and uveitis. Blau syndrome is caused by inborn or de novo mutations in…
Abstract Number: 0412 • ACR Convergence 2025
The Association of Obesity with Juvenile Spondyloarthritis
Katelyn Baggett¹, Timothy Brandon² and Pamela Weiss³, ¹Johns Hopkins University, Newtown Square, PA, ²Children's Hospital of Philadelphia, Philadelphia, PA, ³Childrens Hospital of Philadelphia, Philadelphia, PA
Background/Purpose: Childhood obesity is a global public health concern that impacts the health and wellbeing of all children and particularly negatively affects children living with…
Abstract Number: 0358 • ACR Convergence 2025
Different Perspectives between Physicians and Patients on Treatment Priorities and Challenges in Still’s Disease
Gisella Beatrice Beretta¹, Luciana Pereira², Greta Rogani³, Francesco Baldo⁴, Claudia Bracaglia⁵, Dirk Foell⁶, Marco Gattorno⁷, Marija Jelusic⁸, Sebastiaan Vastert³, Rashmi Sinha⁹ and Francesca Minoia¹⁰, ¹Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy, Milan, Italy, ²Systemic JIA Foundation, Cincinnati, ³University Medical Center Utrecht, Utrecht, Utrecht, Netherlands, ⁴ASST-Pini-CTO, Milano, Milan, Italy, ⁵IRCCS Ospedale Pediatrico Bambino Gesu', Rome, Rome, Italy, ⁶University Hospital Muenster, Muenster, Germany, ⁷IRCCS G. Gaslini, Genova, Genoa, Italy, ⁸University of Zagreb School of Medicine, University Hospital Centre Zagreb, Zagreb, Zagreb, Croatia, ⁹Systemic JIA Foundation, Cincinnati, OH, ¹⁰Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Milan, Italy
Background/Purpose: Despite therapeutic advances, major concerns and disparities persist in the care of Still’s Disease (SD). Capturing both patient/caregiver and physician perspectives is essential to…
Abstract Number: 2181 • ACR Convergence 2025
A Pilot High-Fidelity Simulation for Pediatric Rheumatology Learners
John Bridges¹, Livie Timmerman² and Nicholas Rockwell³, ¹University of Alabama at Birmingham/Children's of Alabama, Birmingham, AL, ²University of Alabama at Birmingham, Gardendale, AL, ³University of Alabama at Birmingham, Birmingham
Background/Purpose: The ACGME’s core competencies for pediatric residency training include medical knowledge, patient care, and interpersonal communication skills. At our institution, residents only spend two…
Abstract Number: 2142 • ACR Convergence 2025
Multidisciplinary Rheumatology Transition Clinic for Young Adults Shows Improved Experience, Utilization, and Health Maintenance: A Mixed-Methods Evaluation
Hannah Concannon¹, Jasmine Oesch², Sara Mazzarelli², Anne Fields², Keisha-Gaye O'Garo² and Rebecca Sadun³, ¹Duke University School of Medicine, Chapel Hill, NC, ²Duke University School of Medicine, Durham, NC, ³Duke University, Durham, NC
Background/Purpose: The transition from pediatric to adult care can pose a challenge for patients with SLE and other rheumatic diseases. These patients often face preventable…
Abstract Number: 1826 • ACR Convergence 2025
Single Nuclei Multiome of JDM Muscle Biopsies Reveals Novel Upregulation of Inflammatory and Vascular Pathways
Shannon O'Connor, Casey Swoboda, Matthew Weirauch, Alexander Zygmunt, Douglas Millay and Leah Kottyan, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
Background/Purpose: Juvenile dermatomyositis (JDM) is a multisystem vasculopathy and inflammatory myopathy characterized by proximal muscle weakness, distinct rash, and risk of long-term complications such as…

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