Abstracts tagged "Pediatric rheumatology"

Abstract Number: 0735 • ACR Convergence 2020
Paediatric Sarcoidosis: Phenotype of a Retrospective Cohort of Biopsy-proven Patients
Kerstin Nott¹, Veronica Nott² and Sandrine Compeyrot-Lacassagne¹, ¹Great Ormond Street Hospital for Children, London, United Kingdom, ²Imperial College, ANDOVER, United Kingdom
Background/Purpose: Paediatric sarcoidosis is a multisystemic inflammatory condition characterised by the formation of non-caseating granulomata that may lead to end-organ damage. Diagnosis is challenging as…
Abstract Number: 1167 • ACR Convergence 2020
Capturing the Range of Disease Involvement in Localized Scleroderma: The Total Morbidity Score
Suzanne Li¹, Aashka Patel¹, Elena Pope², Thomas Mason³, Vidya Sivaraman⁴, Fatma Dedeoglu⁵, Kathryn Torok⁶, Katie Stewart⁷, Gloria Higgins⁸, C. Egla Rabinovich⁹, Robert Fuhlbrigge¹⁰, Maria Ibarra¹¹, Sandy Hong¹², Polly Ferguson¹³, Mara Becker¹⁴, Brian Feldman¹⁵, Ronald Laxer¹⁵ and CARRA Investigators¹⁶, ¹Hackensack University Medical Center, Hackensack, ²Hospital For Sick Kids, Toronto, ON, Canada, ³Mayo Clinic, Rochester, MN, ⁴Nationwide Children's Hospital, Bexley, OH, ⁵Boston Children's Hospital, Boston, MA, ⁶University of Pittsburgh, Pittsburgh, PA, ⁷UT Southwestern, Dallas, TX, ⁸Nationwide Childrens Hospital/ The Ohio State University, Columbus, OH, ⁹Duke University Hospital, Durham, NC, ¹⁰University of Colorado, Denver, CO, ¹¹Children's Mercy Kansas City, Kansas City, MO, ¹²University of Iowa Stead Family Children's Hospital, Iowa City, IA, ¹³University of Iowa Carver College of Medicine, Iowa City, IA, ¹⁴Duke University School of Medicine, Durham, NC, ¹⁵The Hospital for Sick Children, Toronto, ON, Canada, ¹⁶CARRA, Durham
Background/Purpose: Localized scleroderma (LS) is a chronic inflammatory and fibrosing disease that causes both cutaneous and extracutaneous (EC) damage. EC involvement (ECI) is common in juvenile…
Abstract Number: 1509 • ACR Convergence 2020
Leukocyte Telomere Length and Childhood Onset of Systemic Lupus Erythematosus in the Black Women’s Experiences Living with Lupus (BeWELL) Study
John Bridges¹, Kara Chung², Connor Martz², Emily Smitherman¹, Cristina Drenkard³, S. Sam Lim⁴ and David Chae², ¹University of Alabama at Birmingham, Birmingham, AL, ²Auburn University, Auburn, AL, ³Division of Rheumatology, Department of Medicine, Emory School of Medicine, Atlanta, GA, ⁴Emory University, Atlanta, GA
Background/Purpose: Childhood-onset SLE is generally more aggressive than adult-onset SLE. Leukocyte telomere length (LTL) has been posited to reflect immune system aging. Short LTL in…
Abstract Number: 1676 • ACR Convergence 2020
Neuropsychiatric Involvement in Juvenile-onset Systemic Lupus Erythematosus (JSLE): Data from the UK JSLE Cohort Study
Teresa Giani¹, Eve Smith², Rolando Cimaz³, Michael Beresford⁴ and Christian Hedrich², ¹AOU Meyer, Florence, Italy, ²University of Liverpool, Liverpool, United Kingdom, ³ASST Gaetano Pini-CTO Institute and Università degli Studi di Milano, Milan, Italy, Milan, Italy, ⁴Department of Women's & Children's Health, Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool, United Kingdom
Background/Purpose: Juvenile-onset systemic lupus erythematosus (JSLE) is a rare autoimmune/inflammatory disease, accounting for up to 20% of SLE cases. Though clinically similar to adult-onset disease,…
Abstract Number: 1694 • ACR Convergence 2020
Risk Factors Associated with Pneumocystis Jirovecii Pneumonia in Juvenile Myositis in North America
Sara Sabbagh¹, Jessica Neely², Albert Chow³, Marietta DeGuzman⁴, Jamie Lai⁵, Svetlana Lvovich⁶, Tara McGrath⁷, Maria Pereira⁸, Iago Pinal-Fernandez⁹, Jordan Roberts¹⁰, Kelly Rouster-Stevens¹¹, Heinrike Schmeling¹², Anjali Sura¹³, Gabriel Tarshish¹⁴, Lori Tucker¹⁵, Lisa G. Rider¹⁶ and Susan Kim¹⁷, ¹Medical College of Wisconsin, Fox Point, WI, ²UCSF, San Francisco, CA, ³Loma Linda University, San Bernardino, CA, ⁴Baylor College of Medicine, Houston, ⁵University of Colorado, The Woodlands, TX, ⁶St Christopher's Hospital for Children, Philadelphia, PA, ⁷University of British Columbia, Vancouver, BC, Canada, ⁸Baylor College of Medicine, Houston, TX, ⁹National Institutes of Health, Bethesda, MD, ¹⁰Boston Children's Hospital, Boston, MA, ¹¹Emory University/Children's Healthcare of Atlanta, Atlanta, GA, ¹²University of Calgary, Calgary, AB, Canada, ¹³Upstate University Hospital, Syracuse, NY, ¹⁴Children's Hospital at Montefiore, New York, NY, ¹⁵BC Children's Hospital, Vancouver, BC, Canada, ¹⁶Environmental Autoimmunity Group, Clinical Research Branch, NIEHS, NIH, Garrett Park, MD, ¹⁷UCSF Benioff Children's Hospital, San Francisco, CA
Background/Purpose: Pneumocystis jirovecii pneumonia (PJP) is associated with significant morbidity and mortality in adult myositis patients; however, few studies have examined PJP in juvenile myositis…
Abstract Number: 0712 • ACR Convergence 2020
Switching from Reference to Biosimilars Does Not Reduce Efficacy and Safety in Juvenile Idiopathic Arthritis
Ilaria Maccora¹, Gabriele Simonini², Alessandra Bettiol³, Ilaria Pagnini⁴, Niccolò Lombardi⁵, Valerio Maniscalco⁶, Giada Crescioli⁵, Edoardo Marrani⁷, Roberto Bonaiuti⁵, Maria Vincenza Mastrolia⁸, Claudia Ravaldi⁹ and Alfredo Vannacci⁵, ¹Paediatric Rheumatology Unit, Anna Meyer Children's University Hospital, School of Human Health Science, Florence, Italy, Florence, Italy, ²Rheumatology Unit, Meyer Children's University Hospital, Florence; NEUROFARBA Department, University of Florence, Italy, Florence, Italy, ³2. Department of Neurosciences, Psychology, Drug Research and Child Health, Section of Pharmacology and Toxicology, University of Florence, Florence, Italy, Florence, ⁴1. Rheumatology Unit, Anna Meyer Children’s Hospital and Department of Neurosciences, Psychology, Drug Research and Child Health, Section of Paediatric, University of Florence, Florence, Italy, florence, Italy, ⁵2. Department of Neurosciences, Psychology, Drug Research and Child Health, Section of Pharmacology and Toxicology, University of Florence, Florence, Italy., Florence, Italy, ⁶1. Rheumatology Unit, Anna Meyer Children’s Hospital and Department of Neurosciences, Psychology, Drug Research and Child Health, Section of Paediatric, University of Florence, Florence, Italy., florence, Italy, ⁷University of Florence, Firenze, Italy, ⁸Rheumatology Unit, Meyer Children's University Hospital, Firenze, Italy, Florence, Toscana, Italy, ⁹3. Department of Health Sciences, University of Florence, Florence, Italy., Florence, Italy
Background/Purpose: Limited data about the use of biosimilar are available in children with Juvenile Idiopathic Arthritis (JIA). To evaluate the long-term efficacy and safety of switching…
Abstract Number: 0736 • ACR Convergence 2020
Identification of Salient Resilience Domains Among Adolescents with Chronic Musculoskeletal Pain and Their Parents
Lauren Pianucci¹, Maitry Sonagra², Daneka Stryker³ and Sabrina Gmuca⁴, ¹Arcadia University, Philadelphia, ²Children's Hospital of Philadelphia, Cherry Hill, NJ, ³Drexel University College of Medicine, Philadelphia, PA, ⁴Children's Hospital of Philadelphia, Philadelphia, PA
Background/Purpose: Adolescents with chronic musculoskeletal pain (CMP) and their parents have been found to have low to moderate levels of resilience and resilience levels are…
Abstract Number: 1168 • ACR Convergence 2020
Reliability and Validity of a New Skin Activity Measure for Localized Scleroderma
Suzanne Li¹, Mara Becker², Sandy Hong³, Polly Ferguson⁴, Themba Nyrienda¹, Tracy Andrews⁵, Katie Stewart⁶, C. Egla Rabinovich⁷, Robert Fuhlbrigge⁸, Thomas Mason⁹, Elena Pope¹⁰, Maria Ibarra¹¹, Fatma Dedeoglu¹², Gloria Higgins¹³, Ronald Laxer¹⁴, Marilynn Punaro⁶, Kathryn Torok¹⁵ and CARRA Investigators¹⁶, ¹Hackensack University Medical Center, Hackensack, ²Duke University School of Medicine, Durham, NC, ³University of Iowa Stead Family Children's Hospital, Iowa City, IA, ⁴University of Iowa Carver College of Medicine, Iowa City, IA, ⁵Rutgers, Newark, ⁶UT Southwestern, Dallas, TX, ⁷Duke University Hospital, Durham, NC, ⁸University of Colorado, Denver, CO, ⁹Mayo Clinic, Rochester, MN, ¹⁰Hospital For Sick Kids, Toronto, ON, Canada, ¹¹Children's Mercy Kansas City, Kansas City, MO, ¹²Boston Children's Hospital, Boston, MA, ¹³Nationwide Childrens Hospital/ The Ohio State University, Columbus, OH, ¹⁴The Hospital for Sick Children, Toronto, ON, Canada, ¹⁵University of Pittsburgh, Pittsburgh, PA, ¹⁶CARRA, Durham
Background/Purpose: Juvenile localized scleroderma (jLS) is a chronic inflammatory and fibrosing disease. Treatment is directed towards controlling disease activity to minimize risk for functional impairment…
Abstract Number: 1543 • ACR Convergence 2020
Prevalence of Ultrasound Findings Suggestive of Inflammatory Arthritis in Children with Skin Psoriasis (ChildEchoPso)
Luis Coronel¹, Tania Gudu², Sophie Ruel-Gagné¹, Helen Gouze³, Francois Vidal⁴, Ilaria Padovano⁴, Felice Constantino², Maxime Breban⁴, Emmanuel Mahe⁵ and Maria Antonietta D'Agostino⁶, ¹Hôpital Ambroise-Paré, Boulogne-Billancourt, France, ²Hôpital Ambroise-Paré, Bolougne-Billancourt, France, ³[email protected], Bolougne-Billancourt, France, ⁴Hôpital Ambroise-Paré, Bolougne-Billancourt, ⁵Centre Hospitalier Victor Dupouy, Argenteuil, France, ⁶Paris-Saclay Versailles University, Hôpital Ambroise Paré, Boulogne-Billancourt, France
Background/Purpose: The prevalence of psoriasis in children is estimated between 0.5-1% (1), and can be associated with musculoskeletal involvement, althought the prevalence and typology of…
Abstract Number: 1677 • ACR Convergence 2020
Schizophrenia Genetics and Neuropsychiatric Features in Childhood-Onset Systemic Lupus Erythematosus
Ana C. Ulloa Baez¹, Fangming Liao², Raffaella Carlomagno³, Talia Diaz³, Daniela Dominguez⁴, Deborah Levy³, Lawrence Ng⁵, Earl D. Silverman⁶, Andrea Knight⁷ and Linda Hiraki⁸, ¹Genetics & Genome Biology, Research Institute, The Hospital for Sick Children, Toronto, ON, Canada, ²Genetics & Genome Biology, Research Institute, The Hospital for Sick Children, Toronto, Canada, ³Division of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, ⁴Division of Rheumatology, The Hospital for Sick Children, Toronto, Canada, ⁵Division of Rheumatology, Hospital for Sick Children, Toronto, Canada, ⁶Division of Rheumatology, The Hospital for Sick Children, Translational Medicine, Research Institute, The Hospital for Sick Children, and Department of Paediatrics, University of Toronto., Toronto, ON, Canada, ⁷Division of Rheumatology, The Hospital for Sick Children and Department of Paediatrics, University of Toronto, Toronto, ON, Canada, ⁸Division of Rheumatology, The Hospital for Sick Children, Child Health Evaluative Sciences, Research Institute, The Hospital for Sick Children, and Department of Paediatrics, University of Toronto., Toronto, ON, Canada
Background/Purpose: Prior studies indicate that schizophrenia and systemic lupus erythematosus (SLE) share genetic risk loci. Despite overlapping phenotypic features such as psychosis, little is known…
Abstract Number: 1695 • ACR Convergence 2020
Anti-Melanoma Differentiation Associated Protein 5 (MDA5) Positive Juvenile Dermatomyositis: Focus on the Lung
David Moreno McNeill¹, Miriah Gillispie-Taylor², Kevin Baszis³, Edouard Sayad¹, Manuel Silva Carmona¹ and Tiphanie Vogel¹, ¹Baylor College of Medicine/Texas Children's Hospital, Houston, TX, ²Baylor College of Medicine, Houston, ³Washington Univ School of Medicine, St Louis, MO
Background/Purpose: A subset of juvenile dermatomyositis (JDM), clinically amyopathic dermatomyositis (CADM), is uncommon and mainly described in adults. CADM is classically characterized by skin ulcerations,…
Abstract Number: 0713 • ACR Convergence 2020
Longitudinal Effectiveness of Abatacept in JIA: Results from an Ongoing JIA Registry
Daniel J Lovell¹, Hermine Brunner², Nikolay Tzaribachev³, Esi Morgan², Gabriele Simonini⁴, Thomas Griffin⁵, Ekaterina Alexeeva⁶, John Bohnsack⁷, Andrew Zeft⁸, Gerd Horneff⁹, Richard Vehe¹⁰, Valda Stanevicha¹¹, Stacey Tarvin¹², Maria Trachana¹³, Adam Huber¹⁴, Ilonka Orban¹⁵, Jason Dare¹⁶, Ivan Foeldvari¹⁷, Pierre Quartier¹⁸, Alyssa Dominique¹⁹, Tzuyung Douglas Kou¹⁹, Robert Wong¹⁹, Alberto Martini²⁰ and Nicolino Ruperto²⁰, ¹PRCSG, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, ²Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, ³Pediatric Rheumatology Research Institute, Bad Bramstedt, Germany, ⁴Anna Meyer Children's Hospital, Firenze, Italy, ⁵Levine Children's Hospital, Charlotte, NC, ⁶Scientific Center of Children’s Health of RAMS, Moscow, Russia, ⁷University of Utah and Primary Children's Hospital, Cincinnati, OH, ⁸Cleveland Clinic, Cleveland, OH, ⁹Asklepios Clinic Sankt Augustin, Sankt Augustin, Germany, ¹⁰University of Minnesota, Minneapolis, MN, ¹¹Riga Stradins University, Riga, Latvia, ¹²Riley Children’s Health, Indianapolis, IN, ¹³Aristotle University of Thessaloniki, Thessaloníki, Greece, ¹⁴Dalhousie University, Halifax, NS, Canada, ¹⁵National Institute of Rheumatology and Physiotherapy, Budapest, Hungary, ¹⁶University of Arkansas for Medical Sciences, Little Rock, AR, ¹⁷Hamburg Centre for Pediatric and Adolescent Rheumatology, Hamburg, Germany, ¹⁸Necker-Enfants Malades University Hospital, Assistance Publique-Hopitaux de Paris, Paris, France, ¹⁹Bristol-Myers Squibb Company, Princeton, NJ, ²⁰PRINTO, Istituto Giannina Gaslini, Genova, Italy
Background/Purpose: Abatacept is a selective T-cell co-stimulation modulator approved for use in JIA. Efficacy and safety of abatacept in patients with JIA has been demonstrated…
Abstract Number: 0737 • ACR Convergence 2020
“It’ll Go Away. There’s Nothing Wrong with you:” the Experience of Pain-Related Stigma Among Adolescents with Pain Amplification Syndrome
Emily Wakefield¹, William Zempsky¹, Rebecca Puhl² and Mark Litt³, ¹Connecticut Children's/University of Connecticut School of Medicine, Hartford, CT, ²Rudd Center for Food Policy & Obesity/University of Connecticut, Hartford, CT, ³University of Connecticut School of Medicine, Farmington, CT
Background/Purpose: Chronic pain in adolescence is a complex and significant medical condition, with a reported prevalence of 11-38%.1 Pain amplification syndrome (PAS), which includes fibromyalgia,…
Abstract Number: 1169 • ACR Convergence 2020
Three-Dimensional Analysis of Facial Asymmetry in Craniofacial Scleroderma
Daniel Glaser¹, Christopher Liu² and Kathryn Torok³, ¹UPMC Children's Hospital of Pittsburgh, Piitsburgh, PA, ²Children's Hospital of Pittsburgh, Pittsburgh, PA, ³University of Pittsburgh, Pittsburgh, PA
Background/Purpose: Localized scleroderma (LS) is a rare, progressive autoimmune disease of the skin and underlying connective tissue that can result in devastating functional impairment and cosmetic damage in children. …
Abstract Number: 1612 • ACR Convergence 2020
Assessing Patient Self-Reported Transition Readiness in a Large Pediatric Rheumatology Center
Alexander Alexander¹, Mary Robichaux², Priyanka Moolchandani¹, Cristina Saez¹, Ariel Coleman³, JaLeen Rogers³, Danielle Guffey¹, Anne Dykes³, Miriah Gillispie-Taylor¹ and Tiphanie Vogel⁴, ¹Baylor College of Medicine, Houston, ²Baylor College of Medicine, Houston, TX, ³Texas Children's Hospital, Houston, ⁴Baylor College of Medicine/Texas Children's Hospital, Houston, TX
Background/Purpose: Pediatric rheumatology patients need effective transition from pediatric to adult providers. Texas Children’s Hospital (TCH) rheumatology clinic providers have developed a transition pathway, the…

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