ACR Meeting Abstracts

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Abstracts tagged "Pediatric rheumatology"

  • Abstract Number: 2035 • ACR Convergence 2022

    Elucidating the Factors That Influence the Use of Minor Salivary Gland Biopsy for the Evaluation of Childhood Sjögren’s Disease

    Dizon Brian1, Matthew Basiaga2, Sara Stern3, Akaluck Thatayatikom4, seunghee cha5, Scott Lieberman6, Hemalatha Srinivasalu7 and on behalf of CARRA and the childhood Sjogren's workgroup8, 1National Institutes of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, MD, 2Mayo Clinic, Inver Grove Heights, MN, 3University of Utah, Salt Lake City, UT, 4AdventHealth, Orlando, FL, 5University of Florida, Gainesville, FL, 6University of Iowa, Iowa City, IA, 7Children's National Hospital, Washington, DC, 8Childhood Arthritis and Rheumatology Research Alliance, Bethesda, MD

    Background/Purpose: Sjögren's disease is a rare condition in children. Diagnosis is often delayed because of the lack of pediatric-specific guidelines for childhood Sjögren's disease (cSjD).…
  • Abstract Number: 0036 • ACR Convergence 2022

    Patient-specific and Disease-related Determinants for Cardiovascular Disease (CVD) Risk Stratification in the APPLE (Atherosclerosis Prevention in Paediatric Lupus Erythematosus) Clinical Trial Cohort

    Junjie Peng1, George Robinson1, Stacy P Ardoin2, Laura Schanberg3, Elizabeth Jury1 and Coziana Ciurtin4, 1University College London, London, United Kingdom, 2Division of Rheumatology, Nationwide Children's Hospital and Department of Pediatrics, The Ohio State University, Columbus, OH, 3Duke University Medical Center, Durham, NC, 4Centre for Adolescent Rheumatology Versus Arthritis, Department of Medicine, University College London, London, United Kingdom

    Background/Purpose: The risk of developing cardiovascular disease (CVD) through atherosclerosis in juvenile-onset systemic lupus erythematosus (JSLE) patients is significantly increased. This study aimed to stratify…
  • Abstract Number: 0517 • ACR Convergence 2022

    Cortical Surface Area Correlates with Cognitive Efficiency and Disease Measures in Childhood-Onset Systemic Lupus Erythematosus

    Santiago Arciniegas1, Sarah Mossad2, Tala El Tal3, Victoria Lishak4, Stephanie Fevrier5, Ibrahim Mohamed6, Joanna Law2, Lawrence Ng2, Paris Moaf2, Helen Branson2, Adrienne Davis2, Linda Hiraki7, Deborah Levy8, ashley Danguecan2, George Ibrahim5 and Andrea Knight3, 1University of Toronto/Hospital for Sick Children, Toronto, ON, Canada, 2The Hospital for Sick Children, Toronto, ON, Canada, 3The Hospital for Sick Children, Division of Rheumatology, Department of Paediatrics, University of Toronto, Toronto, ON, Canada, 4The Hospital for Sick Children, Department of Psychology, University of Toronto, Toronto, ON, Canada, 5The Hospital for Sick Children/University of Toronto, Toronto, ON, Canada, 6The Hospital for Sick Children, Neurosciences and Mental Health, Research Institute, ON, Canada 3Institute of Biomedical Engineering, University of Toronto, Brampton, ON, Canada, 7The Hospital for Sick Children, Division of Rheumatology, Department of Paediatrics, University of Toronto, Genetics and Genome Biology, SickKids Research Institute, Toronto, ON, Canada, 8Division of Rheumatology, The Hospital for Sick Children; Child Health Evaluative Services, SickKids Research Institute; Department of Paediatrics, University of Toronto, Toronto, ON, Canada

    Background/Purpose: Cognitive difficulties are common in children with childhood-onset SLE (cSLE), but neuropsychiatric lupus (NPSLE) remains challenging to diagnose and treat. To increase understanding of…
  • Abstract Number: 0872 • ACR Convergence 2022

    Incidence, Risk Factors, and Outcomes of Eosinophilia on IL-1 and IL-6 Inhibitors in Systemic and Non-Systemic Juvenile Idiopathic Arthritis

    Holly Wobma1, Maria Taylor2, Ki Pui Lam1, Helene Brown1, Siobhan Case1, Mia Chandler1, Margaret Chang1, Ezra Cohen1, Megan Day-Lewis1, Olha Halyabar1, Jonathan Hausmann1, Melissa Hazen3, Erin Janssen1, Pui Lee1, Mindy Lo1, Esra Meidan1, Jordan Roberts1, Mary Beth F. Son1, Robert Sundel1, Fatma Dedeoglu1, Peter Nigrovic1, Alicia Casey4, Joyce Chang1 and lauren henderson1, 1Division of Immunology, Boston Children's Hospital, Boston, MA, 2Division of Immunology, Boston Children's Hospital, Brighton, MA, 3Boston Children's Hospital, Boston, MA, 4Division of Pulmonary Medicine, Boston Children's Hospital, Boston, MA

    Background/Purpose: Children with systemic juvenile idiopathic arthritis (sJIA) exposed to IL1/6 inhibitors may develop eosinophilia with an atypical rash, reportedly in association with HLA-DRB1*15:XX. There…
  • Abstract Number: 1303 • ACR Convergence 2022

    Planning Transition in Times of Transition: Is There a Virtual Pathway from Pediatric to Adult Care?

    Ben Danna, Monique Maher, Miriah Gillispie-Taylor and Tiphanie Vogel, Baylor College of Medicine, Houston, TX

    Background/Purpose: The BRIDGE (Baylor Rheumatology Initiative: Developing and Guiding Engagement) program is a quality improvement initiative to develop a safe, comprehensive pathway for our patients…
  • Abstract Number: 1377 • ACR Convergence 2022

    Mental Health Screening in Juvenile Myositis: Preliminary Analysis of a Multicenter Pilot Study

    Kaveh Ardalan1, Lindsay Olson1, Jeffrey Dvergsten2, Ann Reed1, Alison Manning1, Gary Maslow1, Aruna Rikhi1, Brian Feldman3, ashley Danguecan4, Sarah Mossad4, Luana Flores Pereira4, Susan Shenoi5, Stacey Haynes5, Joanna Patten5 and Andrea Knight6, 1Duke University School of Medicine, Durham, NC, 2Duke University Hospital, Durham, NC, 3Division of Rheumatology, The Hospital for Sick Children; Child Health Evaluative Services, SickKids Research Institute; Department of Paediatrics, University of Toronto, Toronto, ON, Canada, 4The Hospital for Sick Children, Toronto, ON, Canada, 5Seattle Children's Hospital and Research Center / University of Washington, Seattle, WA, 6The Hospital for Sick Children, Division of Rheumatology, Department of Paediatrics, University of Toronto, Toronto, ON, Canada

    Background/Purpose: Qualitative studies in juvenile myositis (JM) suggest high rates of emotional distress but the prevalence of mental health comorbidities is not well described. We…
  • Abstract Number: 1929 • ACR Convergence 2022

    Outcomes and Safety of Anakinra for the Treatment of Multisystem Inflammatory Syndrome in Children

    Dizon Brian1, Christopher Redmond2, Emily Gotschlich3, Sangeeta Sule4, Tova Ronis4, Kathleen Vazzana5, Matthew Sherman6, Rachael Connor7, Abigail Bosk4, Niti Dham4, Ashraf Harahsheh4, Elizabeth Wells4, Roberta DeBiasi4 and Hemalatha Srinivasalu4, 1National Institutes of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, MD, 2National Institutes of Health, Rockville, MD, 3FDA, Washington, DC, 4Children's National Hospital, Washington, DC, 5Arnold Palmer Hospital for Children, Orlando, FL, 6Muscle Disease Unit, Laboratory of Muscle Stem Cells and Gene Regulation, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH); Children’s National Hospital, Washington, DC, 7Children's National Medical Center, Washington, DC

    Background/Purpose: Multisystem inflammatory syndrome in children (MIS-C) is a clinical entity distinct from primary COVID-19 infection that resembles Kawasaki disease (KD) and toxic shock syndrome.…
  • Abstract Number: 2057 • ACR Convergence 2022

    Outpatient Visit Adherence and Impact on Disease-related Morbidity in Childhood-onset Systemic Lupus Erythematosus (cSLE)

    Meghan Nelson1, Colleen Mosley2, D. Sofia Villacis-Nunez3, Kelly Rouster-Stevens3 and Amit Thakral3, 1Division of Pediatric Rheumatology, Department of Pediatrics, Emory University School of Medicine; Children's Healthcare of Atlanta, Atlanta, GA, 2Children’s Healthcare of Atlanta, Atlanta, GA, 3Division of Pediatric Rheumatology, Department of Pediatrics, Emory University School of Medicine; Children’s Healthcare of Atlanta, Atlanta, GA

    Background/Purpose: Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease that is associated with significant disease damage, morbidity, and mortality. In comparison to the adult…
  • Abstract Number: 0040 • ACR Convergence 2022

    Plasma Proteomic Signatures in Juvenile Dermatomyositis Highlight Novel Proteins and a Protein Module That Associate with Skin and Global Disease Activity

    Marianne Kerski1, Celine Berthier1, Alex Tsoi1, Sarah Vandenbergen1, Madison McClune1, Corey Powell1, J. Michelle Kahlenberg1 and Jessica Turnier2, 1University of Michigan, Ann Arbor, MI, 2University of Michigan, Saline, MI

    Background/Purpose: Juvenile dermatomyositis (JDM) patients display heterogenous disease phenotypes and treatment response patterns. Our study used a multiplexed proteomics assay for measurement of 3072 proteins…
  • Abstract Number: 0548 • ACR Convergence 2022

    Postural Orthostatic Tachycardia Syndrome, Small Fiber Neuropathy, and Systemic Inflammation: Are They Related?

    Elizabeth Bettini, Carolyn Ramwell, Sangeeta Sule and Jeffery Moak, Children's National Hospital, Washington, DC

    Background/Purpose: Postural Orthostatic Tachycardia Syndrome (POTS) is a dysautonomia associated with chronic autonomic and neuropathic symptoms, including pain in multiple body regions, paresthesia, fatigue, brain…
  • Abstract Number: 0873 • ACR Convergence 2022

    Celiac-Associated Arthritis: Clinical Features, Treatment, and Outcomes

    Ana Luiza Altaffer1 and Pamela Weiss2, 1Children's Hospital of Philadelphia, Philadelphia, PA, 2Children's Hospital of Philadelphia, Glen Mills, PA

    Background/Purpose: Although arthritis is recognized as one of the extra-intestinal manifestations of celiac disease, little is known about the clinical course and outcomes of celiac-associated…
  • Abstract Number: 1348 • ACR Convergence 2022

    We Asked Patients and Families: What Is the Job of a Pediatric Rheumatologist?

    Emily Hause1, Nathan Rubin2, Bryce Binstadt1, Colleen Correll1, Patricia Hobday1, Alison Lerman1, Shawn Mahmud1, Mona Riskalla1, Meghan Ryan3, Zachary Shaheen1 and Danielle Bullock1, 1University of Minnesota, Minneapolis, MN, 2University of Minnesota Masonic Cancer Center, Minneapolis, MN, 3University of Minnesota, Vadnais Heights, MN

    Background/Purpose: Pediatric rheumatology is a highly specialized field, with approximately 300 practicing pediatric rheumatologists in the United States. Prior research into patient understanding of medical…
  • Abstract Number: 1378 • ACR Convergence 2022

    Childhood-onset Systemic Lupus Erythematosus: Long-term Outcomes in a Large Multi-ethnic Ontario Cohort

    Ha-Seul Jeoung1, Kuan Liu1, Roberta Berard2, Wes Fidler3, Janet Pope4, Johannes Roth5, Carter Thorne6, Earl Silverman7 and Deborah Levy8, 1University of Toronto, Toronto, ON, Canada, 2London Health Sciences Centre, London, ON, Canada, 3St. Joseph's Hospital, Thunder Bay, ON, Canada, 4University of Western Ontario, London, ON, Canada, 5University of Ottawa, Ottawa, Canada, 6Southlake Regional Health Centre, Newmarket, ON, Canada, 7The Hospital for Sick Children and University of Toronto, Toronto, ON, Canada, 8Division of Rheumatology, The Hospital for Sick Children; Child Health Evaluative Services, SickKids Research Institute; Department of Paediatrics, University of Toronto, Toronto, ON, Canada

    Background/Purpose: The long-term morbidity and mortality of childhood-onset SLE (cSLE) after transition to adult care is not well documented. The present study aims to fill…
  • Abstract Number: 1930 • ACR Convergence 2022

    Assessing the Number of Children Evaluated for Recurrent Fevers During the COVID-19 Pandemic in North America

    Leanne Mansfield1, Sivia Lapidus2, Matthew Hollander3, Julie Cherian4, Marinka Twilt5, Maryam Piram6, Lakshmi Moorthy7, Brian Nolan8, Geraldina Lionetti9, Eveline Wu10, Heather Tory11, Elizabeth Kessler12, Cassyanne Aguiar13, Sirada Panupattanapong14, Shoghik Akoghlanian15, Felice Adler-Shohet16, Melissa Oliver17, Smriti Mohan18, Patricia DeLaMora19, Karen Durrant20, Theresa Wampler Muskardin21, Samira Nazzar22, Mariana Correia Marques23, Matthew Basiaga24, Tiphanie vogel25, Jamie Lai25, Kathryn Edwards26, Kathryn Garguilo26, Sheila Nolan19, Emily Sheboy Scarcello27, Gabrielle Alonzi28, Ann Szymanski29, Joyce Hui-Yuen30, karen onel31, Fatma Dedeoglu32, Maria Gutierrez33, Grant Schulert34 and CARRA PFAPA/Autoinflammatory Working Group N/A35, 1Hospital for Special Surgery/Weill Cornell Medicine, New York, NY, 2Joseph M. Sanzari Children's Hospital Hackensack University Medical Center, Montclair, NJ, 3University of Vermont Medical Center Children's Hospital, Burlington, VT, 4Renaissance School of Medicine at Stony Brook University, Stony Brook Children’s Hospital, Stony Brook, NY, 5Cumming School of Medicine, University of Calgary, Calgary, AB, Canada, 6CHU Sainte Justine, University of Montreal, Montréal, QC, Canada, 7Rutgers-Robert Wood Johnson Medical School, New Brunswick, NJ, 8Ann & Robert H. Lurie Children's Hospital, Chicago, IL, 9UCSF Benioff Children's Hospitals, Oakland, CA, 10University of North Carolina, Chapel Hill, NC, 11Connecticut Children's Medical Center and University of Connecticut School of Medicine, S Glastonbury, CT, 12Spectrum Health Helen DeVos Children's Hospital, Michigan State University, Grand Rapids, MI, 13Children’s Hospital of The King’s Daughters / Eastern Virginia Medical School, Norfolk, VA, 14Cleveland Clinic Children's, Cleveland, OH, 15Division of Rheumatology, Nationwide Children's Hospital and Department of Pediatrics, The Ohio State University, Columbus, OH, 16University of California, Irvine and Children’s Hospital of Orange County, Orange, CA, 17Indiana University School of Medicine, Indianapolis, IN, 18University of Michigan Medical School, Ann Arbor, MI, 19Boston Children's Health Physicians, New York Medical College, Valhalla, NY, 20Autoinflammatory Alliance, San Francisco, CA, 21Colton Center for Autoimmunity, NYU School of Medicine, New York, NY, 22University of California Los Angeles David Geffen School of Medicine, Los Angeles, CA, 23Children's National Health System/National Institute of Arthritis and Musculoskeletal and Skin Diseases, Bethesda, MD, 24Mayo Clinic, Inver Grove Heights, MN, 25Baylor College of Medicine, Houston, TX, 26Vanderbilt University Medical Center, Nashville, TN, 27Boston Children's Health Physicians, Valhalla, NY, 28Boston Children's Hospital, Boston, MA, 29Johns Hopkins All Children’s Hospital, St. Petersburg, FL, 30Cohen Children’s Medical Center, Hofstra-Northwell School of Medicine, Feinstein Institutes for Medical Research, Queens, NY, 31Hospital for Special Surgery, New York, NY, 32Division of Immunology, Boston Children's Hospital, Boston, MA, 33Johns Hopkins University School of Medicine, Baltimore, MD, 34Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 35CARRA, Washington, DC

    Background/Purpose: The impact of the COVID-19 pandemic on the number of pediatric patients evaluated in North America for recurrent fevers and autoinflammatory diseases is unknown;…
  • Abstract Number: 2064 • ACR Convergence 2022

    Trajectories of Disease Activity in a Longitudinal Registry of Pediatric SLE

    Siobhan Case1, Larry Hill2, Anne Dennos3, Thomas Phillips4, Laura Schanberg5, Emily von Scheven6, Andrea Knight7, Aimee Hersh8 and Mary Beth F. Son9, 1Brigham and Women's Hospital, Boston Children's Hospital, Boston, MA, 2Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, 3Duke University, Durham, NC, 4Duke Clinical Research Institute, Durham, NC, 5Duke University Medical Center, Durham, NC, 6University of California, San Francisco, San Francisco, CA, 7The Hospital for Sick Children, Division of Rheumatology, Department of Paediatrics, University of Toronto, Toronto, ON, Canada, 8University of Utah, Salt Lake City, UT, 9Division of Immunology, Boston Children's Hospital, Boston, MA

    Background/Purpose: Pediatric systemic lupus erythematosus (pSLE) is associated with significant morbidity and multiorgan dysfunction. Single-center studies have described disease activity and damage trajectories for pSLE,…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. Academic institutions, private organizations and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part a scientific presentation or presentation of additional new information that will be available at the time of the meeting) is under embargo until Saturday, November 11, 2023.

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