ACR Meeting Abstracts

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Abstracts tagged "pediatric rheumatology and vasculitis"

  • Abstract Number: 832 • 2018 ACR/ARHP Annual Meeting

    Immunoglobuline a Vasculitis: Comparison between Pediatric and Adult Population

    Martin Brom1, Ignacio Javier Gandino2, Marina Scolnik3, Valeria Scaglioni3, Maria Britos4, Carmen De Cunto4 and Enrique R Soriano3, 1Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Instituto Universitario Hospital Italiano de Buenos Aires, and Fundacion PM Catoggio, Buenos Aires, Argentina, 2Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Instituto Universitario Hospital Italiano de Buenos Aires, and Fundacion PM Catoggio, Argentina., Buenos Aires, Argentina, 3Rheumatology Unit, Internal Medicine Service. Hospital Italiano Buenos Aires. Argentina, Buenos Aires, Argentina, 4Pediatric Rheumatology, Hospital Italiano De Buenos Aires, Buenos Aires, Argentina

    Background/Purpose: Immunoglobuline A (IgA) Vasculitis, formerly known as Henoch-Schönlein purpura, is a small-vessel leukocytoclastic vasculitis due to deposition of IgA1, a subclass of IgA. Although…
  • Abstract Number: 108 • 2017 Pediatric Rheumatology Symposium

    Characteristics and long-term outcome of children and adolescents with initial diagnosis of Behçet’s disease in a tertiary care center in Brazil

    Milagro Raquel Tovar-Avila1, Francisco Hugo Gomes2, Lucenir Da Silva3, Virginia Ferriani4 and Luciana Carvalho2, 1Pediatric Reumatology Division, Ribeirão Preto Medical School - University of São Paulo, Rbeirão Preto, Brazil, 2Pediatric Rheumatology Division, Ribeirão Preto Medical School - University of São Paulo, Ribeirão Preto, Brazil, 3Rheumatology Division, Ribeirão Preto Medical School - University of São Paulo, Ribeirão Preto, Brazil, 4Pediatric Reumatology Division, Ribeirão Preto Medical School - University of São Paulo, Ribeirão Preto, Brazil

    Background/Purpose: Behet's disease (BD) is a rare systemic inflammatory disease with nonspecific clinical presentation that can mimic infections, tumors and other diseases. Diagnostic delay of…
  • Abstract Number: 106 • 2017 Pediatric Rheumatology Symposium

    Atypical manifestations and main misdiagnoses of Takayasu’s arteritis in childhood: a multicenter study of 71 patients

    Gleice Clemente1, Ana Paula Sakamoto2, Silvana B. Sacchetti Sr.3, Virgínia Ferriani4, Flavio Sztajnbok5, Sheila Oliveira6, Blanca Bica7, Andre Cavalcanti8, Teresa Robazzi9, Marcia Bandeira10 and Maria Teresa Terreri2, 1Pediatric Rheumatology Unit, Federal University of São Paulo (UNIFESP - Univesidade Federal de São Paulo), São Paulo, Brazil, 2Pediatric Rheumatology Unit, Federal University of São Paulo (UNIFESP - Universidade Federal de São Paulo), São Paulo, Brazil, 3Pediatric Rheumatology Unit, Irmandade da Santa Casa de Misericórdia de São Paulo, São Paulo, Brazil, 4Department of Pediatrics School of Medicine of Ribeirão Preto, University of São Paulo (USP-RP), Ribeirão Preto, Brazil, 5Paediatric Rheumatology International Trials Organization (PRINTO), Istituto Giannina Gaslini, Genoa, Italy, 6Pediatric Rheumatology, Universidade F Rio De Janeiro, Rio De Janeiro, Brazil, 7Hospital Universitário Clementino Fraga Filho, Rio de Janeiro, Brazil, 8Novartis, Sao Paulo, Brazil, 9Pediatrics, Universidade Federal da Bahia, Salvador, Brazil, 10Pediatric Rheumatology Unit, Hospital Pequeno Príncipe, Curitiba, Brazil

    Background/Purpose:  Takayasu’s arteritis is a chronic inflammatory disease that affects the wall of large and medium-sized blood vessels. At the beginning of the disease, non-specific…
  • Abstract Number: 2396 • 2016 ACR/ARHP Annual Meeting

    Initiation of Dialysis in Pediatric ANCA-Associated Vasculitis

    Karen James1, Rui Xiao2,3, Peter A. Merkel4,5 and Pamela F. Weiss6, 1Pediatric Rheumatology, The Children's Hospital of Philadelphia, Philadelphia, PA, 2Department of Pediatrics, Division of Biostatistics, Children's Hospital of Philadelphia, Philadelphia, PA, 3Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA, 4Penn Vasculitis Center, Division of Rheumatology, University of Pennsylvania, Philadelphia, PA, 5Division of Rheumatology, University of Pennsylvania, Philadelphia, PA, 6Division of Rheumatology, Center for Pediatric Clincial Effectiveness, Children's Hospital of Philadelphia, Philadelphia, PA

    Background/Purpose: ANCA-associated vasculitis (AAV) is a group of rare systemic vasculitidies with significant morbidity and mortality. There have been no comparative effectiveness studies of AAV…
  • Abstract Number: 876 • 2015 ACR/ARHP Annual Meeting

    Damage Develops Early and Is Common in Children with Chronic Systemic Vasculitis

    Lorraine O'Neill1, Marinka Twilt2, Susanne Benseler3, Dirk Föll4, David A. Cabral5 and Raashid Luqmani6, 1University of Oxford, Oxford, United Kingdom, 2Division of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, 3Pediatrics, University of Calgary, Toronto, ON, Canada, 4University of Muenster, Muenster, Germany, 5Pediatrics/Rm K4-121, BC Children's Hospital, Vancouver, BC, Canada, 6Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom

    Background/Purpose:  The chronic primary systemic vasculitides are a group of rare conditions with affected patients subject to a significant burden of morbidity from both the…
  • Abstract Number: 2415 • 2015 ACR/ARHP Annual Meeting

    Use of Plasma Exchange for Children Hospitalized with ANCA-Associated Vasculitis in the United States

    Karen James1, Rui Xiao2, Peter A. Merkel3 and Pamela F. Weiss1, 1Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA, 2Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA, 3Division of Rheumatology, University of Pennsylvania, Philadelphia, PA

    Background/Purpose: ANCA-associated vasculitis (AAV) is a group of rare systemic vasculitidies with significant morbidity and mortality. Plasma exchange (PLEX) has been shown to decrease risk…
  • Abstract Number: 3179 • 2015 ACR/ARHP Annual Meeting

    Diagnosing Childhood Small Vessel CNS Vasculitis

    Marinka Twilt1, Maryam Nabavi Nouri2, Pascal N. Tyrrell3, Anastasia Dropol1, Shehla Sheikh4, Cynthia Hawkins5 and Susanne Benseler6,7, 1Rheumatology, Alberta Children's Hospital, Calgary, AB, Canada, 2Neurology, The Hospital for Sick Childern, Toronto, ON, Canada, 3Department of Medical Imaging, University of Toronto, Toronto, ON, Canada, 4Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, 5Paediatric Laboratory Medicine, The Hospital for Sick Children, Toronto, ON, Canada, 6Alberta Children's Hospital Research Institute/University of Calgary, Calgary, AB, Canada, 7Pediatrics/Alberta Children's Hospital, Department of Pediatrics/University of Calgary, Calgary, AB, Canada

    Background/Purpose: Childhood primary small vessel CNS vasculitis (SVcPACNS) is an increasingly recognized inflammatory brain disease with high morbidity and mortality mandating an elective brain biopsy…
  • Abstract Number: 2903 • 2014 ACR/ARHP Annual Meeting

    Early Outcomes in Pediatric Antineutrophil Cytoplasmic Antibody (ANCA) Associated Vasculitis (AAV)

    Kimberly Morishita1, Susanne Benseler2, Rae S.M. Yeung3, Thomas Mason II4, Dawn Wahezi5, Kenneth N. Schikler6, Erica F. Lawson7, Susan Nielsen8, Sirirat Charuvanij9, Paul Dancey10, Susan Shenoi11, Linda Wagner-Weiner12, Angelyne Sarmiento1, David A. Cabral13 and For the PedVas Initiative1, 1BC Children's Hospital and University of British Columbia, Vancouver, BC, Canada, 2Pediatrics/Alberta Children's Hospital, Department of Pediatrics/University of Calgary, Calgary, AB, Canada, 3Rheumatology, The Hospital for Sick Children and University of Toronto, Toronto, ON, Canada, 4Division of Rheumatology - Department of Medicine, Mayo Clinic, Rochester, MN, 5Pediatric Rheumatology, Children's Hospital at Montefiore, Bronx, NY, 6Department of Pediatrics, Univ of Louisville Schl of Med, Louisville, KY, 7Pediatrics, University of California, San Francisco, San Francisco, CA, 8Pediatric rheumatology, Rigshospitalet, Copenhagen, Denmark, 9Pediatrics, Siriraj Hospital, Bangkok, Thailand, 10Pediatrics, Janeway Children's Hospital, St. John's, NL, Canada, 11Pediatric Rheumatology, Seattle Childrens Hospital, seattle, WA, 12Pediatric Rheumatology, University of Chicago Hospital, Chicago, IL, 13Pediatrics, BC Children's Hospital and University of British Columbia, Vancouver, BC, Canada

    Background/Purpose:  Childhood AAV is rare and outcome studies are limited.  The PedVas Study is an international initiative collecting clinical data (to A Registry of Childhood…
  • Abstract Number: 1661 • 2013 ACR/ARHP Annual Meeting

    The Spectrum of childhood Inflammatory Brain Diseases; An Increasingly Recognised Field

    Marinka Twilt1, Eyal Muscal2, Tania Cellucci3, Pavla Dolezalova4, Rob Forsyth5, Susan Kim6, David A. Cabral7, Johannes Roth8, Adam Kirton9, Rolando Cimaz10, Jasmin Kummerle-Deschner11, Annet van Royen-Kerkhof12, Jürgen Brunner13, Gaelle Chedeville14, Jordi Anton15, Angela Robinson16, Mary Toth17, Tilmann Kallinich18, Claudia Bracaglia19, Alexis Boneparth20, Shehla Sheikh21 and Susanne M. Benseler21, 1Division of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, 2TCH Pediatric Rheum Center, Baylor College of Medicine, Houston, TX, 3Rheumatology, Hamilton Health Sciences, McMaster, Hamilton, ON, Canada, 4Pediatric Rheumatology Unit, Department of Pediatrics and Adolescent Medicine, General University Hospital in Prague, Prague, Czech Republic, 5Newcastle upon Tyne's NHS foundation Trust, Newcastle upon Tyne, United Kingdom, 6Division of Immunology, Boston Children's Hospital, Boston, MA, 7University of British Columbia, Vancouver, BC, Canada, 8University of Ottawa, Ottawa, ON, Canada, 9Neurology, Alberta Children's Hospital, Calgary, AB, Canada, 10Rheumatology Unit, A. Meyer Children's Hospital, Florence, Italy, 11University Childrens Clinic Tuebingen, Tuebingen, Germany, 12Department of Pediatric Immunology & Rheumatology, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, Netherlands, 13pediatric Rheumatology, University Children's Hospital, Innsbruck, Austria, 14Pediatric Rheumatology, Montreal Children's Hospital, Montreal, QC, Canada, 15Rheumatology, Hospital Sant Joan de Deu, Barcelona, Spain, 16Pediatrics, Rainbow Babies & Children's Hospital / Case Medical Center, Cleveland, OH, 17Rheumatology, Akron Children's Hospital, Akron, OH, 18Charite, University Medicine Berlin, Berlin, Germany, 19Department of Pediatric Medicine, Division of Rheumatology, Ospedale Pediatrico Bambino Gesù, IRCCS, Rome, Italy, 20Pediatrics, The Children's Hospital at Montefiore, Bronx, NY, 21Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada

    Background/Purpose: Childhood Inflammatory Brain diseases are potentially life-threatening diseases leading to severe neurological deficits if not treated. The spectrum of childhood inflammatory brain diseases is…
  • Abstract Number: 750 • 2013 ACR/ARHP Annual Meeting

    Maintenance Treatment In Childhood Granulomatosis With Polyangiitis

    Marinka Twilt1, Rayfel Schneider2, Diane Hebert3, Elizabeth Harvey3, Ronald M. Laxer2, Sharon Dell4, Christoph Licht3 and Susanne M. Benseler2, 1Division of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, 2Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, 3Nephrology, The Hospital for Sick Children, Toronto, ON, Canada, 4Respiratory Medicine, The Hospital for Sick Children, Toronto, ON, Canada

    Background/Purpose: Granulomatosis with Polyangiitis (GPA) is a rare but life threatening disease. Most children present with pulmonary bleeds and/or renal failure. Most treatment regimens are…
  • Abstract Number: 2195 • 2013 ACR/ARHP Annual Meeting

    Expanding The Spectrum Of Recombination Activating Gene-1 Deficiency To Include Early Onset Autoimmunity

    Lauren A. Henderson1, Francesco Frugoni1, Gregory Hopkins2, Helen de Boer2, Sung-Yun Pai2,3, Yu Nee Lee1, Jolan E. Walter4, Melissa M. Hazen1 and Luigi D Notarangelo5,6, 1Division of Immunology, Boston Children's Hospital, Boston, MA, 2Division of Hematology and Oncology, Boston Children's Hospital, Boston, MA, 3Division of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, 4Division of Allergy/Immunology, Massachusetts General Hospital for Children, Boston, MA, 5Division of Immunology and The Manton Center for Orphan Disease Research, Boston Children's Hospital, Boston, MA, 6Harvard Stem Cell Institute, Boston, MA

    Background/Purpose: We sought to identify the etiology of early onset autoimmunity and T cell lymphopenia in two siblings through genetic and functional studies.  Newborn screening…
  • Abstract Number: 295 • 2012 ACR/ARHP Annual Meeting

    Brain Biopsy Diagnosis in Magnetic Resonance Imaging Negative Childhood Primary Angiitis of the Central Nervous System

    Senq-J Lee1, Cynthia Hawkins2, Suzanne Laughlin3, Shehla Sheikh4 and Susanne M. Benseler4, 1Division of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, 2Paediatric Laboratory Medicine, The Hospital for Sick Children, Toronto, ON, Canada, 3Diagnostic Imaging, The Hospital for Sick Children, Toronto, ON, Canada, 4Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada

    Background/Purpose: Primary CNS vasculitis in childhood (cPACNS) is a devastating inflammatory brain disease mandating rapid and accurate diagnostic evaluation, in order to optimize neurologic outcomes. …
  • Abstract Number: 304 • 2012 ACR/ARHP Annual Meeting

    Burden of Childhood Central Nervous System Vasculitis: Identifying High Risk Factors for Poor Cognitive Outcome

    Peter J. Gowdie1, Marinka Twilt1, Pascal N. Tyrrell1, Robyn Westmacott2, Tania Cellucci1, Shehla Sheikh1, Nick Blancette1 and Susanne M. Benseler1, 1Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, 2Psychology, The Hospital for Sick Children, Toronto, ON, Canada

    Background/Purpose: Childhood primary angiitis of the CNS (cPACNS) is an increasingly recognized, reversible cause of severe neurological and psychiatric deficit such as stroke, refractory seizures…
  • Abstract Number: 279 • 2012 ACR/ARHP Annual Meeting

    Distribution of Vasculitides in Childhood Arthritis and Rheumatology Research Alliance-Affiliated Pediatric Rheumatology Centers in the United States

    Melissa A. Lerman1, Peter A. Merkel2 and for the CARRA Registry Investigators3, 1Division of Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA, 2University of Pennsylvania, Philadelphia, PA, 3Stanford, CA

    Background/Purpose: The epidemiology of pediatric vasculitis is poorly described.  Two studies in the 1990s described the frequency in pediatric rheumatology centers in the United States…
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