Session Type: Abstract Submissions
Session Time: 5:30PM-7:00PM
Methods: This Brazilian multicenter retrospective study included 71 children and adolescents with Takayasu’s arteritis diagnosed before their 19th birthday and followed up in 10 pediatric rheumatology centers. Patients’ clinical, laboratorial and angiographic data were recorded.
Results: Of the 71 patients, 51 (72%) were girls. The mean age at onset was 9.2 years and the mean time to diagnosis was 1.2 years. Eleven (15.5%) patients had diagnoses other than Takayasu’s arteritis at the beginning of the disease. The most common misdiagnosis was rheumatic fever, which was the initial diagnosis in 7 patients (2 of them had cardiac involvement). The other diagnoses before the correct diagnosis of Takayasu’s arteritis were spondiloarthropaty, juvenile idiopathic arthritis (JIA), arteriovenous malformation and JIA with polyarteritis nodosa. We also found 10 atypical manifestations of Takayasu’s arteritis, as follows: pyoderma gangrenosum (present in 2 patients), erythema nodosum, myositis, chorea, tendinitis, episcleritis, uveitis, hepatomegaly, splenomegaly and necrosis of extremities.
Conclusion: Our study demonstrated that there are a variety of misdiagnoses that can be made at the beginning of the disease and also there are some atypical manifestations that can contribute to the difficulty in diagnosing Takayasu’s arteritis.
To cite this abstract in AMA style:Clemente G, Sakamoto AP, Sacchetti SB Sr., Ferriani V, Sztajnbok F, Oliveira S, Bica B, Cavalcanti A, Robazzi T, Bandeira M, Terreri MT. Atypical manifestations and main misdiagnoses of Takayasu’s arteritis in childhood: a multicenter study of 71 patients [abstract]. Arthritis Rheumatol. 2017; 69 (suppl 4). https://acrabstracts.org/abstract/atypical-manifestations-and-main-misdiagnoses-of-takayasus-arteritis-in-childhood-a-multicenter-study-of-71-patients/. Accessed May 19, 2022.
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ACR Meeting Abstracts - https://acrabstracts.org/abstract/atypical-manifestations-and-main-misdiagnoses-of-takayasus-arteritis-in-childhood-a-multicenter-study-of-71-patients/