ACR Meeting Abstracts

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Abstracts tagged "pediatric rheumatology and scleroderma"

  • Abstract Number: 2149 • 2018 ACR/ARHP Annual Meeting

    Assessing the Prevalence of Localized Scleroderma in Childhood Using Dministrative Claims Data from the United States

    Timothy Beukelman1, Fenglong Xie2 and Ivan Foeldvari3, 1Pediatric Rheumatology, University of Alabama at Birmingham, Birmingham, AL, 2University of Alabama at Birmingham, Birmingham, AL, 3Hamburg Center for Pediatric and Adolescent Rheumatology, Hamburg, Germany

    Background/Purpose: Juvenile Localised Scleroderma (jlSc) is believed a rare autoimmune disease, which occurs 10 times more often then systemic sclerosis in childhood and is believed…
  • Abstract Number: 1119 • 2018 ACR/ARHP Annual Meeting

    Genetic Signatures from RNA Sequencing of Pediatric Localized Scleroderma (LS) Skin

    Emily Mirizio1, Roosha Mandal2, Qi Yan3, William Horne4, Kaila Schollaert-Fitch3 and Kathryn S. Torok5, 1Peds Rheum, University of Pittsburgh Med Ctr, Pittsburgh, PA, 2Carnegie Mellon University, Pittsburgh, PA, 3University of Pittsburgh Med Ctr, Pittsburgh, PA, 4Health Sciences Sequencing Core at Children's Hospital of Pittsburgh, Pittsburgh, PA, 5Pediatric Rheumatology, University of Pittsburgh Med Ctr, Pittsburgh, PA

    Background/Purpose: Localized scleroderma (LS) is a progressive disease of the skin and underlying tissue that causes significant functional disability and disfigurement, especially in developing children.…
  • Abstract Number: 2346 • 2017 ACR/ARHP Annual Meeting

    Chemokine Ligand 9 (CXCL9) [Monokine Induced By Gamma Interferon (MIG)]  As a Predictor of Active Disease Status in Localized Scleroderma

    Kathryn S. Torok1, Qi Mi2, Emily Mirizio3, Kaila Schollaert-Fitch1, Mark Fritzler4 and Marvin J. Fritzler5, 1Pediatric Rheumatology, University of Pittsburgh Med Ctr, Pittsburgh, PA, 2Department of Sports Medicine and Nutrition, University of Pittsburgh, Pittsburgh, PA, 3Pediatric Rhuematology, University of Pittsburgh Med Ctr, Pittsburgh, PA, 4Eve Technologies, Calgary, AB, Canada, 5Medicine, University of Calgary, Calgary, AB, Canada

    Background/Purpose: Localized scleroderma (LS) is a fibrotic autoimmune disease of the skin and underlying tissues which can lead to disfiguring sequlea, especially in childhood-onset.  Untreated…
  • Abstract Number: 1023 • 2015 ACR/ARHP Annual Meeting

    Tumor Necrosis Factor-a (TNF-a) and Interferon Gamma Inducible Protein-10 (IP-10) As Predictors of Active Disease Status in Localized Scleroderma

    Kathryn S. Torok1, Jonathan Yabes2, Qi Mi3, Christina Kelsey1 and Kelsey Magee4, 1Pediatric Rheumatology, Univ of Pittsburgh Med Ctr, Pittsburgh, PA, 2Department of Medicine, University of Pittsburgh, Pittsburgh, PA, 3Department of Sports Medicine and Nutrition, University of Pittsburgh, Pittsburgh, PA, 4Pediatrics, University of Pittsburgh, Pittsburgh, PA

    Background/Purpose:   Localized scleroderma has both inflammatory and fibrotic components contributing to its effect on the skin and underlying tissue.   The extent and duration of…
  • Abstract Number: 1897 • 2014 ACR/ARHP Annual Meeting

    Circulating T-Helper Cell- Associated Cytokines and Chemokines in Localized Scleroderma

    Kathryn S. Torok1, Katherine Kurzinski2, Christina Kelsey3, Kelsey Magee4, Jonathan Yabes5, Abbe N. Vallejo6, Thomas A. Medsger Jr.7 and Carol A. Feghali-Bostwick8, 1Pediatric Rheumatology, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, 2Pediatric Rheumatology, Univ of Pittsburgh Med Ctr, Pittsburgh, PA, 3Pediatric Rheumatology, University of Pittsburgh/UPMC, Pittsburgh, PA, 4Pediatric Rheumatology, University of Pittsburgh, Pittsburgh, PA, 5Department of Medicine, University of Pittsburgh, Pittsburgh, PA, 6Department of Immunology, University of Pittsburgh, Pittsburgh, PA, 7Medicine/Rheumatology, University of Pittsburgh, Pittsburgh, PA, 8Medicine, Medical University of South Carolina, Charleston, SC

    Background/Purpose: Localized scleroderma (LS) is an autoimmune disease of the skin and underlying tissues which results in disfigurement and orthopedic complications, especially when the onset…
  • Abstract Number: 2029 • 2012 ACR/ARHP Annual Meeting

    Reliability of Scoring a Disease Damage Measure for Juvenile Localized Scleroderma

    Kathryn S. Torok1, Suzanne C. Li2, Christina Kelsey3, Mara L Becker4, Fatma Dedeoglu5, Robert C. Fuhlbrigge6, Gloria Higgins7, Sandy D. Hong8, Maria F. Ibarra9, Ronald Laxer10, Thomas G. Mason II11, Marilynn G. Punaro12, Elena Pope13, C. Egla Rabinovich14 and Katie G. Stewart12, 1Pediatric Rheumatology, Scleroderma Center of Pittsburgh, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, 2Pediatrics, Joseph M Sanzari Children's Hospital, Hackensack University Medical Center, Hackensack, NJ, 3Pediatric Rheumatology, Univ of Pittsburgh Med Ctr, Pittsburgh, PA, 4Clinical Pharmacology and Rheumatology, Children's Mercy Hospital, Kansas City, MO, 5Division of Immunology, Boston Children's Hospital, Boston, MA, 6Pediatric Rheumatology, Childrens Hospital, Boston, MA, 7Pediatric Rheumatology NATIONWIDE CHILDRENS HOSPITAL, PRCSG-Cincinnati Children's Hospital Medical Center, Columbus, OH, 8Pediatrics-Rheumatology, U of Iowa Children's Hosp, Iowa City, IA, 9Pediatric Rheumatolgy, Children's Mercy Hospital, Kansas City, MO, 10Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, 11Rheumatology, Mayo Clinic Rochester, Rochester, MN, 12Pediatric Rheumatology, Texas Scottish Rite Hospital, Dallas, TX, 13Dermatology, The Hospital for Sick Children, Toronto, ON, Canada, 14Pediatric Rheumatology, Duke University Medical Center, Durham, NC

    Background/Purpose: .    In order to more accurately capture disease activity and damage in juvenile Localized Scleroderma (jLS) and to develop an accepted outcome measure for…
  • Abstract Number: 2036 • 2012 ACR/ARHP Annual Meeting

    Children’s Hospital of Pittsburgh Pediatric Onset En Coup De Sabre and Parry-Romberg Syndrome Cohort

    Kristin M. Brown1, Darren Smith2, Christina Kelsey3, Katherine Kurzinski4 and Kathryn S. Torok5, 1Pediatric Rheumatology, University of Pittsburgh, Pittsburgh, PA, 2Plastic and Reconstructive Surgery, university of Pittsburgh Division of Plastic and Reconstructive Surgery, Children's Hospital of Pittsburgh, Pittsburgh, 3Pediatric Rheumatology, Univ of Pittsburgh Med Ctr, Pittsburgh, PA, 4Pediatric Rheumatology, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, 5Pediatric Rheumatology, Scleroderma Center of Pittsburgh, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA

    Background/Purpose: Localized scleroderma is an autoimmune disease characterized by disfiguring thickening and fibrosis of the skin and underlying soft tissues; the majority of cases have…
  • Abstract Number: 2008 • 2012 ACR/ARHP Annual Meeting

    Initial Evaluation of a Localized Scleroderma (LS) Clinical Activity Measure

    Suzanne C. Li1, Kathryn S. Torok2, Christina Kelsey3, Mara L Becker4, Fatma Dedeoglu5, Robert C. Fuhlbrigge6, Gloria C. Higgins7, Sandy D. Hong8, Maria F. Ibarra9, Ronald Laxer10, Thomas G. Mason II11, Marilynn G. Punaro12, Elena Pope13, C. Egla Rabinovich14 and Katie G. Stewart12, 1Pediatrics, Joseph M Sanzari Children's Hospital, Hackensack University Medical Center, Hackensack, NJ, 2Pediatric Rheumatology, Scleroderma Center of Pittsburgh, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, 3Pediatric Rheumatology, Univ of Pittsburgh Med Ctr, Pittsburgh, PA, 4Clinical Pharmacology and Rheumatology, Children's Mercy Hospital, Kansas City, MO, 5Division of Immunology, Boston Children's Hospital, Boston, MA, 6Pediatric Rheumatology, Childrens Hospital, Boston, MA, 7Pediatric Rheumatology Ohio State University, Nationwide Childrens Hosp, Columbus, OH, 8Pediatrics-Rheumatology, U of Iowa Children's Hosp, Iowa City, IA, 9Pediatric Rheumatolgy, Children's Mercy Hospital, Kansas City, MO, 10Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, 11Rheumatology, Mayo Clinic Rochester, Rochester, MN, 12Pediatric Rheumatology, Texas Scottish Rite Hospital, Dallas, TX, 13Dermatology, The Hospital for Sick Children, Toronto, ON, Canada, 14Pediatric Rheumatology, Duke University Medical Center, Durham, NC

    Background/Purpose: LS commonly causes severe morbidity for the growing child. Optimal therapy is not known and the lack of an agreed-upon standard for assessing disease…
  • Abstract Number: 319 • 2012 ACR/ARHP Annual Meeting

    Gamma Interferon-Induced Protein-10 (IP-10) As a Potential Biomarker for Disease Activity in Pediatric Localized Scleroderma

    Katherine Kurzinski1, Carol A. Feghali-Bostwick2, Christina Kelsey1, Kelsey Magee3 and Kathryn S. Torok4, 1Pediatric Rheumatology, Univ of Pittsburgh Med Ctr, Pittsburgh, PA, 2Medicine, University of Pittsburgh, Pittsburgh, PA, 3Pediatric Rheumatology, University of Pittsburgh, Pittsburgh, PA, 4Pediatric Rheumatology, Scleroderma Center of Pittsburgh, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA

    Background/Purpose: Pediatric localized scleroderma (LS) is an autoimmune disease affecting the skin and underlying tissue.  Cutaneous findings assist in categorizing the patients into active or…
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