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Abstracts tagged "Pediatric rheumatology"

  • Abstract Number: 2446 • ACR Convergence 2025

    Use of Voclosporin in Pediatric Patients: A Summary of Available Data from Post-marketing Reports

    Eugenia Chock1, Ankana Daga2, Tasim Begum3, Kathryn Dao3 and Michelle Dardeno3, 1Yale School of Medicine, New Haven, CT, 2Boston Children's Hospital, Boston, MA, 3Aurinia Pharmaceuticals Inc., Rockville, MD

    Background/Purpose: Lupus nephritis (LN) is common in pediatric patients with systemic lupus erythematosus (SLE), with more than 50% developing renal manifestations, typically within the first…
  • Abstract Number: 2150 • ACR Convergence 2025

    Rheum to Grow:An Approach Towards Human Centered Design through a Qualitative Analysis on the Transition from Pediatric to Adult Rheumatology

    Lillian Chang1, Rhea Sharma2, Elyse Guziewicz1, Jordan Jackson3, Katrina Romagnoli1, Gemme Campbell1, Saritha Korukonda1, Priyanka Pawar1, Jonida Cote4, Thomas Davis1 and Emily Brunner1, 1Geisinger, Danville, PA, 2Geisinger Medical Center Internal Medicine Residency, Danville, PA, 3Geisinger Medical Center Medicine-Pediatrics Residency, Danville, PA, 4Geisinger Health System, Wilkes-Barre, PA

    Background/Purpose: Up to half of patients who transition to adult care are lost to follow up within 2 years of transfer from pediatric to adult…
  • Abstract Number: 2126 • ACR Convergence 2025

    Preliminary Results of a Large, Global Registry Characterizing Childhood-Onset Takayasu Arteritis

    Muserref Kasap Cuceoglu1, James Bistolarides2, Mario Sestan3, Samuel Gagne4, Nick McPhate5, Kimberly Morishita6, Vidya Sivaraman7, Linda Wagner-Weiner8, Seza Özen9, Marija Jelusic10 and David Cabral11, 1Hacettepe University, Ankara, Turkey, 2Medical College of Wisconsin, Wauwatosa, WI, 3University of Zagreb School of Medicine, Zagreb, Croatia, 4University of Pittsburgh, Pittsburgh, PA, 5BC Children's Hospital, Vancouver, Canada, 6University of British Columbia, Vancouver, BC, Canada, 7Nationwide Children's Hospital/ The Ohio State University, Columbus, OH, 8University of Chicago, Chicago, IL, 9Hacettepe University Medical Faculty, Ankara, Turkey, 10University of Zagreb School of Medicine, University Hospital Centre Zagreb, Zagreb, Zagreb, Croatia, 11BC Children's Hospital and University of British Columbia, Vancouver, BC, Canada

    Background/Purpose: The rarity of childhood-onset Takayasu arteritis (c-TAK) has resulted in small cohorts for study that has limited the potential for evaluating its course and…
  • Abstract Number: 1810 • ACR Convergence 2025

    Destabilized Treg Cells Predominant in Severe Forms of Juvenile Idiopathic Arthritis

    Ki Pui Lam1, Claudia Harris2, Jennifer Cheng3, Lwiza AitDowd4, Maryam Ashoor5, Ahmad Bakhsh3, Carrie Bryant3, Siobhan Case6, Mia Chandler3, Joyce Chang3, Ezra Cohen7, Fatma Dedeoglu3, Olha Halyabar8, Jonathan Hausmann9, Melissa Hazen3, Sonia Iosim10, Liyoung Kim11, Jeffrey Lo3, Mindy Lo3, Emma Materne3, Esra Meidan12, Megan Perron13, Helene Powers10, Mary Beth Son3, Holly Wobma3, Margaret Chang3, Pui Lee14, Peter Nigrovic11 and Lauren Henderson15, 1Division of Immunology, Boston Childrens Hospital, Harvard Medical School, Boston, MA, 2Division of Immunology, Boston Childrens Hospital, Boston, MA, 3Boston Children's Hospital, Boston, MA, 4Boston Children's Hospital, Harvard Medical School, Boston, MA, 5Division of Immunology, Boston Children’s Hospital, Harvard Medical School, Brookline, MA, 6UpToDate, Brigham and Women's Hospital, Boston Children's Hospital, Boston, MA, 7Bmc, NEEDHAM, MA, 8Children's Hospital/Boston Medical Center, Newton, MA, 9Boston Children's Hospital / Massachusetts General Hospital, Cambridge, MA, 10Division of Immunology, Boston Children’s Hospital, Harvard Medical School, Boston, MA, 11Boston Children's Hospital, Brookline, MA, 12Boston Children's Hospital, Somerville, MA, 13Division of Immunology, Boston Children’s Hospital, Harvard Medical School, Natick, MA, 14Boston Children's Hospital, Newton, MA, 15Boston Children's Hospital, Watertown, MA

    Background/Purpose: T peripheral helper (Tph) cells stimulate excessive B cell responses in the joints of patients with autoantibody-positive arthritis, including seropositive RA in adults and…
  • Abstract Number: 1575 • ACR Convergence 2025

    Clinical presentation, course, treatment and outcome of juvenile onset versus adult onset mixed connective tissue disease patients: a multicenter retrospective cohort.

    Kevin Chevalier1, Brigitte Bader-Meunier2, Isabelle Kone-Paut3, Benjamin Torreau4, Marc Michel5, Bertrand Godeau5, Christian AGARD6, Thomas Papo7, Karim Sacré8, Raphaele Seror9, Xavier Mariette10, Cacoub Patrice11, Ygal Benhamou12, Mathilde Leclercq13, Cécile goujard14, Olivier Lambotte3, Bernard Bonnotte15, Maxime Samson16, Félix Ackermann17, Jean Schmidt18, Pierre Duhaut18, Jean-Emmanuel Kahn19, Thomas Hanslik19, Nathalie Costedoat-Chalumeau20, Benjamin Terrier20, Alexis REGENT21, bertrand Dunogue22, Pascal Cohen23, Véronique Le Guern20, Eric HACHULLA24, Luc Mouthon22 and Benjamin Chaigne22, 1Université Paris Cité, Montrouge, France, 2Necker hospital, Paris, France, 3Bicêtre hospital, Kremlin Bicêtre, France, 4Internal Medicine and Immunology, CHU Tours, Tours, France, 5Henri Mondor hospital, Créteil, France, 6Internal medicine, Nantes University Hospital, Nantes, France, 7Bichat hospital, Paris, France, 8Department of Internal Medicine, Bichat University Hospital, Université Paris Cité, AP-HP, Paris, France, Paris, France, 9Department of Rheumatology, National referral center for auto immune disease and Sjogren disease, Université Paris-Saclay, INSERM UMR1184: Centre for Immunology of Viral Infections and Autoimmune Diseases, Assistance Publique-Hôpitaux de Paris, Hôpital Bicêtre, Le Kremlin Bicêtre, Paris, France., le kremlin bicetre, France, 10Université Paris-Saclay, Le Kremlin Bicetre, France, 11Department of Internal Medicine and Clinical Immunology, Sorbonne Universités, AP-HP, Groupe Hospitalier Pitié-Salpêtrière, Centre national de références Maladies Autoimmunes et systémiques rares, Centre national de références Maladies Autoinflammatoires rares et Amylose inflammatoire (CEREMAIA), INSERM, UMR S959, Immunology-Immunopathology-Immunotherapy (I3), Paris, France, Paris, France, 12Internal Medicine, CHU Rouen, Rouen, France, 13Rouen hospital, Rouen, France, 14Université Paris Saclay, Department of Internal Medicine and Clinical Immunology, Bicêtre Hospital, APHP, UMR1184 Inserm, CEA, Le Kremlin Bicêtre, France, Kremlin Bicêtre, France, 15Internal medicine and clinical immunology, Université Bourgogne Europe , CHU Dijon Bourgogne, Dijon, France, 16CHU Dijon Bourgogne, Dijon, France, 17Foch hospital, Suresnes, France, 18Amiens hospital, Amiens, France, 19Ambroise Paré hospital, Boulogne, France, 20Cochin hospital, Paris, France, 21Hopital Cochin, Paris, France, 22Department of Internal Medicine, National Referral Center for Rare Systemic Autoimmune Diseases, Cochin University Hospital, Université Paris Cité, AP-HP, Paris, France, 23Department of Internal Medicine, National Referral Center for Rare Systemic Autoimmune Diseases, Hospital Cochin, Paris, France, 24CHU Lille, Département de Médecine Interne et Immunologie Clinique, Centre de Référence des Maladies Auto-Immunes et Auto-Inflammatoires Rares du Nord, Nord-Ouest, Méditerranée et Guadeloupe (CeRAINOM), Lille, France, Lille, France

    Background/Purpose: Mixed connective tissue disease (MCTD) is an entity defined by clinical features of differentiated connective tissue diseases (dCTD), such as systemic lupus erythematosus (SLE),…
  • Abstract Number: 1290 • ACR Convergence 2025

    Adverse Childhood Experiences: Prevalence and Relationship to Disease and Mental Health Outcomes in Childhood-Onset Systemic Lupus Erythematosus (cSLE)

    Jin Xuan Zhou1, Stephanie Fevrier2, Paris Moaf2, Lawrence Ng3, Asha Jeyanathan4, Louise Boulard2, Deborah Levy1, Linda Hiraki1, Ashley Danguecan5 and Andrea Knight5, 1The Hospital for Sick Children, Toronto, ON, Canada, 2Hospital for Sick Children, Toronto, Canada, 3The Hospital for Sick Children, Toronto, Canada, Toronto, ON, Canada, 4The Hospital for Sick Children, Toronto, Canada, 5Hospital for Sick Children, Toronto, ON, Canada

    Background/Purpose: Childhood-onset systemic lupus erythematosus (cSLE) is an autoimmune disease characterized by multi-organ inflammation, alongside high frequencies of mood disorders and cognitive impairment. Adverse Childhood…
  • Abstract Number: 1273 • ACR Convergence 2025

    Effectiveness of IV Cyclophosphamide and Mycophenolate Mofetil in the Treatment of Pediatric Systemic Lupus Erythematosus with Lupus Nephritis

    adrienne katrin guiang-valerio, University of Santo Tomas Hospital, Mandaluyong, National Capital Region, Philippines

    Background/Purpose: Lupus nephritis (LN) is more common in children (occurs in 50-82%) compared to adults. Cyclophosphamide (CYC) and mycophenolate mofetil (MMF) are both treatment options…
  • Abstract Number: 0421 • ACR Convergence 2025

    Inflammatory Orbital Diseases: Pediatric Case Series From a Tertiary Care Center

    Rasha Elrefai1, Katherine Williams2 and Hannah Bradfield3, 1Baylor College of Medicine, Houston, TX, 2Texas Children's Hospital, Houston, TX, 3Baylor College of Medicine/Texas Children's Hospital, Houston, TX

    Background/Purpose: Orbital inflammatory diseases in the pediatric population present diagnostic and therapeutic challenges due to variable clinical manifestations, limited prospective data, and lack of standardized…
  • Abstract Number: 0394 • ACR Convergence 2025

    Predictors of quality of Life in a longitudinal cohort of patients with Uveitis, Juvenile Idiopathic Arthritis, and JIA-associated uveitis

    andressa Guariento Ferreira Alves1, Amy Cassedy2, Virginia Miraldi Utz3, Alexandra Duell3, Megan Quinlan-Waters4, Nicole Reitz5, Sheila Angeles-Han6 and Melissa Lerman7, 1The Children's Hospital of Philadelphia, Philadelphia, PA, 2Cincinnati Children's hospital medical center, cincinnati, OH, 3Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 4Cincinnati Children's Hospital Medical Center, CCHMC, 5Department of Mental Health, St. Louis, MO, 6Cincinnati Children's Hospital, Cincinnati, OH, 7Children's Hospital of Philadelphia, Philadelphia, PA

    Background/Purpose: Uveitis, juvenile idiopathic arthritis (JIA), and JIA-associated uveitis (JIA-U) greatly influence children's quality of life (QOL). Our aim is to identify demographic, disease, and…
  • Abstract Number: 2423 • ACR Convergence 2025

    Clinical and Sociodemographic Factors Associated with Diagnostic Delays in Pediatric Lupus Patients

    Michaela Harter1, Rebecca Hetrick2, James Slaven3 and Martha Rodriguez4, 1Indiana University School of Medicine, Indianapolis, IN, 2Indiana University School of Medicine, Zionsville, IN, 3Indiana University School of Medicine, Indianapolis, 4Riley Hospital For Children At Indiana University, Carmel, IN

    Background/Purpose: Early recognition and treatment of juvenile systemic lupus erythematosus (jSLE) improves outcomes and prevents disease-related mortality. This study examines the contributions of clinical factors…
  • Abstract Number: 2149 • ACR Convergence 2025

    Rheumatology Transitions of Care: Patient Stability and Follow-Up at a Single Center

    Julia Witowska1, Marianne Kerski1, Uzochi Nwoko2, Lakshmi Meyyappan2, Catherine McDermott2 and Jacqueline Madison1, 1University of Michigan, Ann Arbor, MI, 2University of Michigan, Ann Arbor

    Background/Purpose: The transition period for adolescents transferring from pediatric to adult care is a recognized period of vulnerability. In rheumatology, the majority of adolescents reach…
  • Abstract Number: 2125 • ACR Convergence 2025

    Development and Validation of Minimal Clinically Important Difference for Children with Chronic Nonbacterial Osteomyelitis Using a Consensus and Data-Driven Approach

    Farzana Nuruzzaman1, Natalie Rosenwasser2, Xing Wang3, Ava Klein3, Ian Muse4, Erin Balay-Dustrude5, Megan Nguyen6, Emily Deng3, Jonathan Akikusa7, Matthew Basiaga8, Lindsey Bergstrom9, Fatma Dedeoglu10, Bin Huang11, Jenna King12, Sivia Lapidus13, Tzielan Lee14, Cassandra Levesque15, Aleksander Lenert16, Lillian Lim17, Kimberly Martin18, Elizabeth Murray19, Melissa Oliver20, Karen Onel21, Seza Özen22, Lauren Potts23, Sara M. Stern24, Robin Villaverda25, Eveline Wu26, Ronald laxer27, Polly Ferguson28, Daniel Lovell29 and Yongdong (Dan) Zhao30, 1Stony Brook Children's Hospital, Stony Brook, NY, 2Seattle Children's Hospital, seattle, WA, 3Seattle Children's Hospital, Seattle, 4University of Washington, Department of Pediatrics, Seattle Children's Hospital, Seattle, 5University of Washington, Seattle, WA, 6Seattle Children’s Research Institute, Seattle, 7The Royal Children's Hospital, Parkville, Victoria, Australia, 8Mayo Clinic, Rochester, MN, 9Patient/parent research partner, Harpswell, ME, 10Boston Children's Hospital, Boston, MA, 11Cincinnati Children's Hospital, Cinciannati, OH, 12Patient/parent Research Partner, Planation, FL, 13Joseph M. Sanzari Children's Hospital, Center for Discovery and Innovation, Hackensack Meridian School of Medicine, Montclair, NJ, 14Stanford University School of Medicine, Palo Alto, CA, 15Patient/parent research partners, DC district, DC, 16Iowa Carver College of Medicine, Iowa City, IA, 17University of Alberta, Edmonton, AB, Canada, 18Patient/parent research partners, Houston, TX, 19Patient/parent research partners, Lynnwood, WA, 20Indiana University, Indianapolis, IN, 21HSS, New York, NY, 22Hacettepe University Medical Faculty, Ankara, Turkey, 23Patient/parent research partners, Santa Cruiz, CA, 24University of Utah, Salt Lake City, UT, 25Patient/parent research partners, Thorton, CO, 26UNC Chapel Hill, Chapel Hill, NC, 27The Hospital for Sick Children, Toronto, ON, Canada, 28University of Iowa Carver College of Medicine, Iowa City, IA, 29Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 30Seattle Children’s Research Institute, Redmond, WA

    Background/Purpose: Chronic nonbacterial osteomyelitis (CNO) is an inflammatory bone disease that can result in bone deformity, persistent pain and pathological fractures which is frequently treated…
  • Abstract Number: 1809 • ACR Convergence 2025

    Mass Spectrometry-Based N-Terminomics Uncovers Proteolytic Signatures and Pathways in Juvenile Idiopathic Arthritis Synovial Fluid

    Andrew Zeft1, Sirada Panupattanapong2, Laura Nedorezov3, Sumit Bhutada3 and Suneel Apte3, 1Cleveland Clinic, Cleveland, OH, 2Cleveland Clinic Foundation, Cleveland, OH, 3Cleveland Clinic, Cleveland

    Background/Purpose: Juvenile idiopathic arthritis (JIA) is a chronic disease marked by persistent synovial inflammation, often leading to structural joint damage. While numerous proteases produced by…
  • Abstract Number: 1495 • ACR Convergence 2025

    Comparing the 0-10 Physician Global Assessment Scale to Categorical Disease Activity States among Pediatric Patients with SLE

    Livie Timmerman1, Melissa Mannion2 and Emily Smitherman2, 1University of Alabama at Birmingham, Gardendale, AL, 2University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose: The Physician Global Assessment (PGA) is used to measure disease activity on a 0–10 scale for many pediatric rheumatic conditions. However, the thresholds at…
  • Abstract Number: 1289 • ACR Convergence 2025

    Longitudinal Exploration of Pain and Disease Characteristics in Youth with Childhood-Onset Lupus

    Jida Jaffan1, Tala El Tal2, Lawrence Ng3, Asha Jeyanathan4, Hunter Hogarth5, Adrienne Davis4, Linda Hiraki5, Deborah Levy5, Zahi Touma6, Natoshia Cunningham7, Ashley Danguecan8 and Andrea Knight8, 1The Hospital for Sick Children/ University of Toronto, Toronto, ON, Canada, 2Children's Hospital of Eastern Ontario (CHEO), Ottawa, ON, Canada, 3The Hospital for Sick Children, Toronto, Canada, Toronto, ON, Canada, 4The Hospital for Sick Children, Toronto, Canada, 5The Hospital for Sick Children, Toronto, ON, Canada, 6University of Toronto, Toronto, ON, Canada, 7Michigan State University, Grand Rapids, MI, 8Hospital for Sick Children, Toronto, ON, Canada

    Background/Purpose: Pain is a common symptom in childhood-onset systemic lupus erythematosus (cSLE) which impacts health-related quality of life. Its relationship to disease measures over time…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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