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Abstracts tagged "Patient reported outcomes"

  • Abstract Number: 0147 • ACR Convergence 2020

    The Interpretation of Patient-reported Outcomes in Rheumatoid Arthritis: Do Clinical Trials Adequately Evaluate Meaningful Improvements for Patients?

    Peter Taylor1, Robin Dore2, Kate Williams3, Sarah Acaster3, Jenya Antonova4 and Mark Genovese5, 1Botnar Research Centre, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom, 2Private practice, Tustin, CA, 3Acaster Lloyd Consulting, London, United Kingdom, 4Gilead Sciences, Foster City, CA, 5Gilead Sciences, Inc., Foster City, CA

    Background/Purpose: The importance of patient-relevant outcomes, such as pain, fatigue and physical functioning, has been long established in the field of rheumatoid arthritis (RA). Patient-reported…
  • Abstract Number: 0236 • ACR Convergence 2020

    Safety and Usability of Infliximab Administration by Auto-injector (AI) and Pre-filled Syringe (PFS) in Patients with Active Rheumatoid Arthritis (RA): Patient-reported Experience from a Multicenter, Randomized Controlled Pivotal Trial

    Rene Westhovens1, DaeHyun Yoo2, Piotr Wiland3, Marek Zawadzki4, Delina Ivanova5, Alfredo Berrocal Kasay6, Elias Chalouhi7, Eva Balázs8, SangJoon Lee9, SungHyun Kim9, JeeHye Suh9, NooRi Han9 and HoJae Lee9, 1University Hospitals Leuven, Belgium, Leuven, Belgium, 2Hanyang University Hospital for Rheumatic Diseases, Seoul, Republic of Korea, 3Medical Univeristy, Wroclaw, Poland, 4Medical Univeristy, Dpt of Rheumatology , Wroclaw, Wroclaw, Poland, 5Diagnostic-Consultative Center Aleksandrovska EOOD, Sofia, Bulgaria, 6ABK Reuma SRL, LIMA, Peru, 7Clinica Internacional Sede Lima, Lima, Peru, 8Dr. Bugyi István Hospital, Szentes, Hungary, 9Celltrion, Inc., Incheon, Republic of Korea

    Background/Purpose: The subcutaneous (SC) formulation of CT-P13 received marketing authorization for RA from the EMA by demonstrating non-inferiority compared to CT-P13 intravenous for efficacy in…
  • Abstract Number: 0360 • ACR Convergence 2020

    Does Smoking Affect Secukinumab Treatment Outcomes and Safety in Patients with Psoriatic Arthritis? – Real World Data from German Observational Study

    Elke Riechers1, Uta Kiltz2, Jan Brandt-Jürgens3, Peter Kästner4, Daniel Peterlik5 and Hans-Peter Tony6, 1Hannover Medical School, Hannover, Germany, 2Rheumazentrum Ruhrgebiet, Ruhr-University Bochum, Herne, Germany, 3Rheumatologische Schwerpunktpraxis Berlin, Berlin, Germany, 4Ambulantes Rheumazentrum, Erfurt, Germany, 5Novartis Pharma GmbH, Nürnberg, Germany, 6Rheumatology/Clinical Immunology, Department of Internal Medicine II, Würzburg, Germany

    Background/Purpose: Several studies have shown an negative association between smoking status and psoriatic arthritis (PsA) clinical outcomes1,2. The German non-interventional study AQUILA provides real-world data…
  • Abstract Number: 0884 • ACR Convergence 2020

    Comparison of Disease Control Thresholds in Psoriatic Arthritis: Results from the Corrona Psoriatic Arthritis/Spondyloarthritis Registry

    Philip Mease1, Robert McLean2, Taylor Blachley2, Laura Anatale-Tardiff3, Christopher Saffore4, Patrick Zueger4 and Alexis Ogdie5, 1Seattle Rheumatology Associates, P.L.L.C., Seattle, WA, 2Corrona, LLC, Waltham, MA, 3Corrona, LLC, Waltham, 4AbbVie Inc., North Chicago, IL, 5University of Pennsylvania, Philadelphia, PA

    Background/Purpose: There is no single accepted measure of low/minimal disease activity (LDA/MDA) for patients with PsA; thus, describing the characteristics of real-world patients meeting different…
  • Abstract Number: 1214 • ACR Convergence 2020

    Association Between Changes in C-reactive Protein at Week 12 and Patient-Reported Outcomes at Week 24 with Sarilumab Therapy Across Three Pivotal Phase 3 Studies

    John Tesser1, Grace Wright2, Vibeke Strand3, Jeffrey Kaine4, Karina Maslova5, Gregory St John6, Kerri Ford5, Amy Praestgaard5 and Ernest Choy7, 1Arizona Arthritis & Rheumatology Associates, Phoenix, AZ, 2Association of Women in Rheumatology, New York, NY, 3Division of Immunology/Rheumatology, Stanford University, Palo Alto, CA, 4Independent Rheumatology Consultant, Sapphire, NC, 5Sanofi, Cambridge, MA, 6Regeneron Pharmaceuticals Inc, Tarrytown, NY, 7CREATE Centre, Cardiff University, Cardiff, Wales, United Kingdom

    Background/Purpose: Evaluation of response to RA therapy at 12 weeks after initiation is recommended in treatment guidelines. CRP response after 12 weeks of therapy may…
  • Abstract Number: 1322 • ACR Convergence 2020

    Prevalence and Associated Factors of Sleep Disorders in Patients with Axial Spondyloarthritis. Results from the European Map of Axial Spondyloarthritis (EMAS)

    Marco Garrido-Cumbrera1, Victoria Navarro-Compán2, Laura Christen3, Christine Bundy4, Raj Mahapatra5, Souzi Makri6, Carlos-Jesus Delgado-Domínguez7, José Correa-Fernández8 and Denis Poddubnyy9, 1Health & Territory Research (HTR), Universidad de Sevilla / Spanish Federation of Spondyloarthritis Associations, Sevilla, Spain, 2Hospital Universitario La Paz IdiPaz, Madrid, Pais Vasco, Spain, 3Novartis Pharma AG, Basel, Switzerland, 4Cardiff University, Cardiff, United Kingdom, 5Axial Spondyloarthritis International Federation, London, United Kingdom, 6Cyprus League Against Rheumatism, Nicosia, Cyprus, 7Health & Territory Research, Seville, Spain, 8Health & Territory Research (HTR), Universidad de Sevilla, Sevilla, Spain, 9Charité – Universitätsmedizin Berlin, Berlin, Germany

    Background/Purpose: Sleep is an essential health aspect that is often impacted in patients with axial spondyloarthritis (axSpA). This analysis aims to assess the prevalence and…
  • Abstract Number: 1601 • ACR Convergence 2020

    Pilot Testing Supports Utility of a Point-of-Care Dashboard to Enhance Patient and Clinician Partnerships in the Management of RA

    Stephanie Mathew1, John Mecchella1, Lisa Johnson2, Aricca Van Citters2, Stacy Courtnay3, Jennifer Marden4, Jabeen Ahmad2, Guy Eakin5, Eugene Nelson2, Salahuddin Kazi6 and Scott Pompa1, 1Dartmouth-Hitchcock Medical Center, Lebanon, NH, 2The Dartmouth Institute for Health Policy & Clinical Practice, Lebanon, NH, 3Patient Partner, Atlanta, GA, 4Dartmouth-Hitchcock Medical Center; Patient Partner, Lebanon, NH, 5Arthritis Foundation, Atlanta, GA, 6Veterans Affairs North Texas Healthcare System / UT Southwestern Medical Center, Dallas, TX

    Background/Purpose: Increasing evidence exists that health outcomes are improved when people living with a chronic condition partner with their clinicians to coproduce their care based…
  • Abstract Number: 1889 • ACR Convergence 2020

    Reliability and Validity of the PROMIS-29 Health Profile in Ankylosing Spondylitis Patients

    Yvette Farran1, Alexis Ogdie2, John Reveille3 and Mark Hwang4, 1McGovern Medical School at the University of Texas Health Sciences Center, Houston, TX, 2University of Pennsylvania, Philadelphia, PA, 3Department of Internal Medicine, University of Texas, Houston, TX, 4McGovern Medical School at the University of Texas Health Science Center at Houston, Houston, TX

    Background/Purpose: The Patient Reported Outcomes Measurement Information System 29-Item Profile Measure (PROMIS-29) is a generic measure of health-related quality of life (HRQOL) that has seven…
  • Abstract Number: 0148 • ACR Convergence 2020

    Perspectives on Treatment Burden for Methotrexate and TNF-inhibitors Among Psoriatic Arthritis and Rheumatoid Arthritis Patients: A Qualitative Study

    Alexis Ogdie1, Yomei Shaw2, Michele Almonte3, Ervant Maksabedian4 and Kaleb Michaud5, 1Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 2Forward, The National Databank for Rheumatic Diseases, East Lansing, MI, 3University of Pennsylvania, Philadelphia, PA, 4Amgen Inc., LOS ANGELES, CA, 5University of Nebraska Medical Center, Omaha, NE

    Background/Purpose: Physicians often consider adverse events when choosing therapies for PsA and RA but may give less attention to other ways in which treatments affect…
  • Abstract Number: 0258 • ACR Convergence 2020

    Using Patient-Reported Outcomes Measures to Classify Patients with Systemic Lupus Erythematous

    Amanda Eudy1, Bryce Reeve2, Theresa Coles2, Li Lin2, Jennifer Rogers3, Lisa Criscione-Schreiber4, Jayanth Doss1, Kai Sun1, Rebecca Sadun1, Patricia Katz5, David Pisetsky6 and Megan Clowse7, 1Duke University, Durham, NC, 2Duke University, Durham, 3Duke, Durham, NC, 4Duke University School of Medicine, Durham, NC, 5University of California, San Francisco, Novato, CA, 6Duke University Medical Center, Durham, NC, 7Duke University, Chapel Hill, NC

    Background/Purpose: Because systemic lupus erythematosus (SLE) is a complex and heterogeneous disease, we have developed a conceptual model that divides SLE activity into two dimensions:…
  • Abstract Number: 0377 • ACR Convergence 2020

    Evaluation of Sex Differences in the Efficacy and Safety of Tofacitinib in Patients with Active Psoriatic Arthritis: A Post Hoc Analysis of Two Phase 3 Randomized Controlled Trials

    Lihi Eder1, Dafna Gladman2, Sibel Zehra Aydin3, Alexis Ogdie4, Harry Shi5, Pierre-Alexandre Landry6 and Rayana Luna6, 1Women’s College Research Institute, University of Toronto, Toronto, ON, Canada, 2Krembil Research Institute, Toronto Western Hospital, Toronto, ON, Canada, 3Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Canada, 4Division of Rheumatology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 5Pfizer Inc, Collegeville, PA, 6Pfizer Canada ULC, Kirkland, Canada

    Background/Purpose: Studies indicate that sex (male vs female) is predictive of outcomes with PsA treatments, such as TNF inhibitors (TNFi).1 Tofacitinib is an oral JAK…
  • Abstract Number: 0921 • ACR Convergence 2020

    The Hospital Anxiety and Depression Scale in Patients with Systemic Sclerosis – A Psychometric and Factor Analysis in a Monocentric Cohort

    Alexandru Garaiman1, Carina Mihai1, Rucsandra Dobrota1, Suzana Jordan1, Britta Maurer2, Jan Flemming3, Oliver Distler4 and Mike Oliver Becker1, 1Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland, Zurich, 2Center of Experimental Rheumatology, Department of Rheumatology, University Hospital Zurich, Switzerland, Zurich, 3Department of Consultation-Liaison-Psychiatry and Psychosomatic Medicine, University Hospital Zurich, Zurich, Switzerland, Zurich, Switzerland, 4Center of Experimental Rheumatology, Department of Rheumatology, University Hospital Zurich, Switzerland, Zurich, Switzerland

    Background/Purpose: The Hospital Anxiety and Depression Scale (HADS) is a screening tool used in patients with different medical conditions. However, its validity, reliability and responsiveness…
  • Abstract Number: 1215 • ACR Convergence 2020

    Filgotinib Provided Rapid and Sustained Relief of Pain and Fatigue and Improved Health-Related Quality of Life in Patients with Rheumatoid Arthritis and Inadequate Response to Biologic DMARDs

    David Walker1, Tsutomu Takeuchi2, Beatrix Bartok3, Shangbang Rao3, I-Heng Lee4, Robin Besuyen5, Jacques-Eric Gottenberg6 and Mark Genovese3, 1Northumbria Healthcare Trust, North Shields, United Kingdom, 2Keio Univ School of Medicine, Tokyo, Japan, 3Gilead Sciences, Inc., Foster City, CA, 4Gilead Sciences, Foster City, CA, 5Galapagos BV, Leiden, Netherlands, 6Strasbourg University Hospital, Strasbourg, France

    Background/Purpose: EULAR guidelines recommend a treat-to-target approach focusing on reducing inflammation to prevent joint damage, physical disability, and mortality.1 However, patients consider reduction in pain…
  • Abstract Number: 1341 • ACR Convergence 2020

    Improvement in Patient-Reported Outcomes in Patients with Psoriatic Arthritis with Inadequate Response to Non-Biologic DMARDs Treated with Upadacitinib versus Placebo or Adalimumab: Results from a Phase 3 Study

    Vibeke Strand1, Philip Mease2, Enrique Soriano3, Mitsumasa Kishimoto4, Carlo Salvarani5, Nemanja Damjanov6, Jaclyn K Anderson7, Erin Blondell7, Patrick Zueger7, Christopher Saffore7 and Dafna Gladman8, 1Division of Immunology/Rheumatology, Stanford University, Palo Alto, CA, 2Seattle Rheumatology Associates, P.L.L.C., Seattle, WA, 3Department of Public Health, Instituto Universitario, Escuela de Medicina Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Rheumatology Unit, Internal Medicine Services, Hospital Italiano de Buenos Aires, Capital Federal, Buenos Aires, Argentina, 4Department of Nephrology and Rheumatology, Kyorin University School of Medicine, Yokohama, Japan, 5Rheumatology Units, University of Modena and Reggio Emilia, and Azienda USL-IRCCS di Reggio Emilia, REGGIO EMILIA, Italy, 6University of Belgrade Medical School, Belgrade, Serbia, 7AbbVie Inc., North Chicago, IL, 8Krembil Research Institute, Toronto Western Hospital, Toronto, ON, Canada

    Background/Purpose: Patient-reported outcomes (PROs) are important when evaluating treatment benefits in PsA. We present an analysis of PRO data from the SELECT-PsA 1 study.Methods: SELECT-PsA…
  • Abstract Number: 1615 • ACR Convergence 2020

    Assessing Preparation for Care Transition Among Adolescents with Rheumatologic Disease: A Quality Assessment with Patient Survey

    Jordan Roberts1, Olha Halyabar2, Carter Petty3 and Mary Beth Son1, 1Boston Children's Hospital, Boston, MA, 2Children's Hospital/Boston Medical Center, Boston, MA, 3Boston Childrens Hospital, Institutional Centers for Clinical and Translational Research, Boston, MA

    Background/Purpose: Despite the risk for poor outcomes and gaps in care in the transition from pediatric to adult care, most pediatric rheumatology centers lack formal…
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Embargo Policy

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].

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