ACR Meeting Abstracts

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Abstracts tagged "Patient reported outcomes"

  • Abstract Number: 1596 • ACR Convergence 2020

    Coproduction of Care for Veterans with RA: Improving Elicitation and Documentation of Patient Goals

    Swathi Reddy1, Kyawt Shwin1, Rashmi Arora1, Sarah Homann2, Lisa Johnson3, Yusuf Chao4, Aricca Van Citters3, Brant Oliver5, Guy Eakin6, Eugene Nelson3, Andreas Reimold1 and Salahuddin Kazi1, 1Veterans Affairs North Texas Healthcare System / UT Southwestern Medical Center, Dallas, TX, 2Veterans Affairs Tennessee Valley Healthcare System / Vanderbilt University Medical Center, Nashville, TN, 3The Dartmouth Institute for Health Policy & Clinical Practice, Lebanon, NH, 4UT Southwestern Medical Center, Dallas, TX, 5The Dartmouth Institute for Health Policy & Clinical Practice / Veterans Affairs National Quality Scholars Fellowship in Healthcare Quality & Safety, Lebanon, NH, 6Arthritis Foundation, Atlanta, GA

    Background/Purpose: Coproduction of healthcare services offers a pathway to increase patient engagement in care. Patients and clinicians coproduce care by working together to: (1) co-assess…
  • Abstract Number: 1842 • ACR Convergence 2020

    Repository Corticotropin Injection (Acthar® Gel) for Persistently Active Systemic Lupus Erythematosus: Post Hoc Analyses of Patient-Reported Outcomes from a Phase 4, Multicenter, Randomized, Double-blind, Placebo-Controlled Trial

    Anca Askanase1, George Wan2, Mary Panaccio2, Enxu Zhao2, Julie Zhu2, Roman Bilyk2 and Richard Furie3, 1Columbia University College of Physicians and Surgeons, New York, NY, 2Mallinckrodt Pharmaceuticals, Bedminster, NJ, 3Zucker School of Medicine at Hofstra/Northwell, Great Neck, NY

    Background/Purpose: Repository corticotropin injection (RCI, Mallinckrodt Pharmaceuticals) is a naturally sourced complex mixture of adrenocorticotropic hormone analogs and other pituitary peptides approved for the treatment…
  • Abstract Number: 0143 • ACR Convergence 2020

    Filgotinib Improved Work Productivity and Activity Impairment in Patients with Rheumatoid Arthritis Who Are Methotrexate-naïve: Results from the FINCH-3 Study

    Zobair Younossi1, Maria Stepanova2, Lynn Gerber1, Susan Lee3, Ken Hasegawa3, Thijs Hendrikx4, Annelies Boonen5, Bernard Combe6, David Walker7 and Rieke Alten8, 1Betty and Guy Beatty Center for Integrated Research, Inova Health System, Falls Church, VA, 2Center for Outcomes Research in Liver Disease, Washington, DC, 3Gilead Sciences, Inc., Foster City, CA, 4Galapagos BV, Leiden, Netherlands, 5Maastricht University Medical Center, Maastricht, Netherlands, 6University of Montpellier, Montpellier, France, 7Northumbria Healthcare Trust, North Shields, United Kingdom, 8Schlosspark-Klinik, Universitätsmedizin, Berlin, Germany

    Background/Purpose: Filgotinib (FIL) is a potent oral selective janus kinase 1 inhibitor currently being investigated as an agent to treat rheumatoid arthritis (RA). In the…
  • Abstract Number: 0186 • ACR Convergence 2020

    The Number of Associated Comorbidities Can Impact Disease Activity Scores Independently from Objective Measures of Inflammation in Patients with Rheumatoid Arthritis

    Magali Zanotti-Cavazzoni1 and Gabriela Avila2, 1Sociedad Paraguaya de Reumatología, Asunción, Paraguay, 2Sociedad Paraguaya de Reumatologia, Asuncion, Paraguay

    Background/Purpose: Disease activity scores (DAS) are used as tools to assess persistent inflammation and need for therapeutic escalation in patients with Rheumatoid arthritis (RA). One…
  • Abstract Number: 0356 • ACR Convergence 2020

    Bimekizumab Improves Patient-Reported Outcomes in Psoriatic Arthritis: 48-Week Results from a Phase 2b Study and Association Between Patient-Reported Outcomes and Disease Activity

    Laure Gossec1, Philip Mease2, Alice Gottlieb3, Deepak Assudani4, Jason Coarse5, Barbara Ink6 and Laura Coates7, 1Sorbonne Université and Hôpital Universitaire Pitié Salpêtrière, Paris, France, 2Seattle Rheumatology Associates, P.L.L.C., Seattle, WA, 3Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY, 4UCB Pharma, Slough, United Kingdom, 5UCB Pharma, Raleigh, NC, 6UCB Pharma, Slough, 7University of Oxford, Oxford, United Kingdom

    Background/Purpose: Bimekizumab (BKZ), a humanized monoclonal IgG1 antibody that selectively neutralizes interleukin (IL)-17A and IL-17F, has shown clinical improvements in joint and skin outcomes and…
  • Abstract Number: 0863 • ACR Convergence 2020

    Residual Treatment Burden, Desired Improvement, and Prioritized Treatment Goals in Systemic Lupus Erythematosus (SLE): Results from the SLE-UPDATE (Understanding Preferences, Disease Activity and Treatment Expectations) Survey in the United States

    Diane Kamen1, Julie Birt2, Monica Hadi3, Nashmel Sargalo3, Ella Brookes3, Paul Swinburn3, Leslie Hanrahan4, Karin Tse5, Natalia Bello6, Kirstin Griffing2, Maria Silk2, Laure Delbecque7 and Anca Askanase8, 1Medical University of South Carolina, Charleston, SC, 2Eli Lilly and Company, Indianapolis, IN, 3Evidera, London, United Kingdom, 4Carra Group, Milwaukee, WI, 5Lupus Foundation of America, DC, WA, 6Eli Lilly and Company, Indianapolis, 7Eli Lilly and Company, Brussels, Belgium, 8Columbia University College of Physicians & Surgeons, New York, NY

    Background/Purpose: Literature describes a fairly high degree of satisfaction with SLE therapies, despite patients reporting high rates of adverse event (1-2).  The objectives of this…
  • Abstract Number: 1177 • ACR Convergence 2020

    Rheumatic Diseases in Mexican Children and Their Psychosocial and Economic Impact on Caregivers

    Fernando García Rodríguez1, Brenda de Jesús Fortuna2, Ingris Pelaez-Ballestas3, Enrique Faugier Fuentes4, Samara Mendieta Zerón5, Greta Reyes Cordero6, Sol Jiménez Hernández7, Ana Villarreal Treviño8, Jessica Guadarrama9, Sara Rosiles de la Garza8, Manuel de la O Cavazos8 and Nadina Rubio Pérez10, 1Hospital Universitario "Dr. José E. González", Mexico City, Nuevo Leon, Mexico, 2Hospital Infantil De México Federico Gómez, Monterrey, Nuevo Leon, Mexico, 3Hospital General de Mexico, Mexico, Distrito Federal, Mexico, 4Hospital Infantil de México Federico Gómez, CDMX, Distrito Federal, Mexico, 5ISSEMYM Toluca, Estado de México, Distrito Federal, Mexico, 6Hospital Infantil de Especialidades de Chihuahua, Chihuahua, Chihuahua, Mexico, 7Hospital Universitario "Dr. José E. González", Monterrey, Mexico, 8Hospital Universitario "Dr.José E. González", Monterrey, Nuevo Leon, Mexico, 9Hospital Infantil de México Federico Gómez, CDMX, Distrito Federal, Mexico, 10Hospital Universitario "Dr. José E. González", Monterrey, Nuevo Leon, Mexico

    Background/Purpose: Pediatric rheumatic diseases (PRD) are a heterogeneous group of disorders. PRD patients and their caregivers face a number of challenges, these include the consequences…
  • Abstract Number: 1290 • ACR Convergence 2020

    A Multitrait-Multimethod Matrix Approach to the Construct Validity of Patient Reported Outcomes Measurement Information System Computerized (PROMIS) Adaptive Tests (CAT) in Systemic Lupus Erythematous

    Mitra Moazzami1, Patricia Katz2, Dennisse Bonilla3, Lisa Engel4, Jiandong Su5, Pooneh Akhavan6, Nicole Anderson5, Oshrat Tayer-Shifman7, Dorcas Beaton8 and Zahi Touma9, 1George Washington University School of Medicine, Washington, DC, 2University of California, San Francisco, Novato, CA, 3University Health Network, Toronto, Canada, 4University of Manitoba, Toronto, ON, Canada, 5University of Toronto Lupus Clinic, Centre for Prognosis Studies in Rheumatic Diseases, Toronto Western Hospital, University Health Network, Toronto, ON, Canada, 6Univesity of Toronto, Toronto, ON, Canada, 7Meir Medical Center, Raanana, Israel, 8Institue for Work and Health, Toronto, ON, Canada, 9University of Toronto, Toronto, ON, Canada

    Background/Purpose: Use of The Patient Reported Outcomes Measurement Information System computerized adaptive test (PROMIS-CAT) in adults with systemic lupus erythematous (SLE) is an emerging research…
  • Abstract Number: 1599 • ACR Convergence 2020

    Workflows for Collecting and Using Patient-reported Outcomes Across Rheumatology Practices

    Meera Subash1, Kimberly DeQuattro2, Sonam Choden3, Lucy Liu4, Puneet Bajaj5, Christie Bartels6, Jennifer Barton7, Bonnie Bermas8, Maria (Maio) Danila9, Julianna Desmarais10, Christina Downey11, Sancia Ferguson12, Sarah Goglin13, Margaret Guthrie14, Irum Jan15, Nikila Kumar16, Shraddha Prakash17, Kimberly Reiter18, Elizabeth Wahl19, Elena Weinstein20, JoAnn Zell21, Gabriela Schmajuk22 and Jinoos Yazdany2, 1University of California, San Francisco, San Francisco, CA, 2UCSF, San Francisco, CA, 3University of California, San Francisco, San Francisco, 4Kaiser Permanente, Oakland, CA, 5UT Southwestern, Dallas, TX, 6University of Wisconsin School of Medicine and Public Health, Department of Medicine, Division of Rheumatology, Madison, WI, 7VAPORHCS/OHSU, Portland, OR, 8UTSouthwestern.edu, Dallas, TX, 9University of Alabama at Birmingham (UAB), Birmingham, AL, 10Oregon Health & Science University, Portland, OR, 11Loma Linda University Medical Center, Redlands, CA, 12University of Wisconsin-Madison School of Medicine and Public Health, Department of Medicine, Division of Rheumatology, Oakland, CA, 13University of California San Francisco, Burlingame, CA, 14University of Alabama at Birmingham, DIv. of Clinical immunology & Rheum., Birmingham, AL, 15VA Albuquerque, Albuquerque, 16Arizona Arthritis & Rheumatology Associates, P.C., San Jose, CA, 17Oakcare Medical Group, Pleasanton, CA, 18Albuquerque VA Medical Center, Albuquerque, NM, 19VA Puget Sound Healthcare System, Seattle, WA, 20University of Colorado, Englewood, CO, 21University of Colorado, Denver, CO, 22University of California, San Francisco, Atherton, CA

    Background/Purpose: The use of patient reported outcomes (PROs) during rheumatology visits may facilitate shared decision making and encourage patients to share their health goals. However,…
  • Abstract Number: 1866 • ACR Convergence 2020

    Patient-reported Impact of Axial Spondyloarthritis on Working Life. Results from the Spanish Atlas 2017

    Marco Garrido-Cumbrera1, Eduardo Collantes-Estévez2, Victoria Navarro-Compán3, Pedro Zarco4, Carlos Sastre5, Sergio Sanz-Gomez6, José Correa-Fernández7 and Jordi Gratacós8, 1Health & Territory Research (HTR), Universidad de Sevilla / Spanish Federation of Spondyloarthritis Associations, Sevilla, Spain, 2Rheumatology Department, Reina Sofia University Hospital/ Maimonides Institute for Research in Biomedicine of Cordoba (IMIBIC)/ University of Cordoba, Cordoba, Spain, Córdoba, Spain, 3Hospital Universitario La Paz IdiPaz, Madrid, Pais Vasco, Spain, 4Novartis Farmacéutica Spain, Alcorcon, Madrid, Spain, 5Novartis Pharma AG, Basel, Switzerland, 6Health & Territory Research, Seville, Spain, 7Health & Territory Research (HTR), Universidad de Sevilla, Sevilla, Spain, 8University Hospital Parc Tauli Sabadell, Barcelona, Spain

    Background/Purpose: Axial spondyloarthritis (axSpA) impacts negatively on multiple dimensions of patient’s life, including their working life. The present study aims to evaluate working status, work-related…
  • Abstract Number: 0144 • ACR Convergence 2020

    Age, Income, Education, and Health Conditions Are Associated with Patient Empowerment Among US Adults with Arthritis, but Race and Geography Are Not

    Kathleen Carluzzo1, Erin Knight-Zhang1, Karen Schifferdecker1, Emily Creek2, Rebecca Butcher1 and Guy Eakin2, 1Dartmouth College, Lebanon, NH, 2Arthritis Foundation, Atlanta, GA

    Background/Purpose: The purpose of this study is to understand experiences of empowerment in healthcare visits among US adults with arthritis, and key factors associated with discrepancies…
  • Abstract Number: 0206 • ACR Convergence 2020

    Fifty-Two Week Outcomes of Biologic-Naïve RA Patients Treated with Subcutaneous Abatacept in Japanese Multicenter Investigational Study (ORIGAMI Study)

    Naoto Tamura1, Eiichi Tanaka2, Eisuke Inoue3, Yuri Yoshizawa4, Shigeru Matsumoto5, Hisashi Yamanaka6 and Masayoshi Harigai7, 1Department of Internal Medicine and Rheumatology, Juntendo University School of Medicine, Bunkyō, Tokyo, Japan, 2Department of Rheumatology, Tokyo Women’s Medical University School of Medicine, Tokyo, Japan, 3Department of Rheumatology, Tokyo Women’s Medical University School of Medicine; Showa University Research Administration Center, Showa University, Tokyo, Japan, 4Bristol-Myers Squibb K.K., Tokyo, Japan, 5Ono Pharmaceutical Co., Ltd., Tokyo, Japan, 6Department of Rheumatology, Tokyo Women’s Medical University School of Medicine; Rheumatology, Sanno Medical Center, Tokyo, Japan, 7Department of Rheumatology, Tokyo Women’s Medical University School of Medicine, Shinjuku-ku, Tokyo, Japan

    Background/Purpose: Long-term clinical benefit and patient-reported outcomes (PRO) of subcutaneously-injected abatacept (ABA) in patients with RA in a real-world setting are of therapeutic interest. We…
  • Abstract Number: 0358 • ACR Convergence 2020

    Does Smoking Affect Secukinumab Treatment Outcomes and Safety in Patients with Ankylosing Spondylitis? – Real World Data from German Observational Study

    Elke Riechers1, Uta Kiltz2, Jan Brandt-Jürgens3, Peter Kästner4, Daniel Peterlik5 and Hans-Peter Tony6, 1Hannover Medical School, Hannover, Germany, 2Rheumazentrum Ruhrgebiet, Ruhr-University Bochum, Herne, Germany, 3Rheumatologische Schwerpunktpraxis Berlin, Berlin, Germany, 4Ambulantes Rheumazentrum, Erfurt, Germany, 5Novartis Pharma GmbH, Nürnberg, Germany, 6Rheumatology/Clinical Immunology, Department of Internal Medicine II, Würzburg, Germany

    Background/Purpose: There is growing body of evidence that smoking is associated with more active and severe disease in patients (pts) with ankylosing spondylitis (AS)1,2. The…
  • Abstract Number: 0873 • ACR Convergence 2020

    Impact of Skin Involvement on Disease Burden Among Patients with Psoriatic Arthritis: Data from the Corrona Psoriatic Arthritis/Spondyloarthritis Registry

    Philip Mease1, Robert McLean2, Taylor Blachley2, Laura Anatale-Tardiff3, Christopher Saffore4, Charlie Lovan5 and Alexis Ogdie6, 1Seattle Rheumatology Associates, P.L.L.C., Seattle, WA, 2Corrona, LLC, Waltham, MA, 3Corrona, LLC, Waltham, 4AbbVie Inc., North Chicago, IL, 5AbbVie Inc., North Chicago, 6University of Pennsylvania, Philadelphia, PA

    Background/Purpose: When deciding to start patients with PsA on biologic therapy, rheumatologists may focus on skin involvement in addition to joint symptoms. The purpose of…
  • Abstract Number: 1201 • ACR Convergence 2020

    Effect of Filgotinib on Pain in Patients with Rheumatoid Arthritis: Results from Phase 3 Clinical Trials

    Peter Taylor1, Arthur Kavanaugh2, Peter Nash3, Janet Pope4, Beatrix Bartok5, Ken Hasegawa5, Shangbang Rao5, Sander Strengholt6 and Rene Westhovens7, 1Botnar Research Centre, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom, 2Division of Rheumatology, Allergy, & Immunology, University of California San Diego Medical School, San Diego, CA, 3School of Medicine Griffith University, Brisbane, Queensland, Australia, 4Department of Medicine, University of Western Ontario, St. Joseph's Health Centre, London, ON, Canada, 5Gilead Sciences, Inc., Foster City, CA, 6Galapagos BV, Leiden, Netherlands, 7University Hospitals Leuven, Belgium, Leuven, Belgium

    Background/Purpose: RA patients (pts) often suffer substantial pain despite ongoing treatment (tx) and regard pain control as a top tx goal. Filgotinib (FIL)—a potent, oral…
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