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Abstracts tagged "pathogenesis and synovial fluid"

  • Abstract Number: 2047 • ACR/ARHP Annual Meeting 2018

    Synovial Fluid Cytokines /Chemokines and Proteins from the Knees of Symptomatic RA and OA Patients Which Correlate with the Magnitude of the Inflammatory Response As Measured By Synovial Fluid WBC Levels

    Richard Meehan1, Eric Hoffman2, Mary Wolf3, Elizabeth Regan4, Prashant Parmar5, Karin Pacheco6, Jim Crooks7 and Vijaya Knight8, 1MEDICINE, National Jewish Health, Denver, CO, 2Medicine/Rheumatology, National Jewish Health, Denver, CO, 3Pathology Department, National Jewish Health, Denver, CO, 4Medicine, National Jewish Health, Denver, CO, 5Internal Medicine, St Joseph Hospital, Denver, CO, 6MEDICINE/ Occupational Medince, National Jewish Health, Denver, CO, 7Biostatistics, National Jewish Health, Denver, CO, 8Pathology, ADX laboratory, National Jewish Health, Denver, CO

    Background/Purpose: Synovial fluid (SF) provides nutritional support for cartilage and contains numerous catabolic and anabolic cytokines, chemokines and proteins. The precise role of these proteins…
  • Abstract Number: 2898 • ACR/ARHP Annual Meeting 2018

    Increased Frequency of Circulating CD4+CXCR5-PD1hi Peripheral Helper T (cTph) Cells in Patients with Seropositive Early Rheumatoid Arthritis (RA)

    Paula Fortea-Gordo1, Laura Nuño2, Alejandro Villalba2, Diana Peiteado3, Irene Monjo4, Paloma Sanchez-Mateos5, Amaya Puig-Kröger6, Alejandro Balsa1 and Maria Eugenia Miranda-Carus1, 1Rheumatology, Hospital La Paz - IdiPAZ, Madrid, Spain, 2Rheumatology, La Paz University Hospital, Madrid, Spain, 3Hospital Universitario La Paz, Madrid, Spain, 4Rheumatology, Rheumatology, La Paz University Hospital, Madrid, Spain, 5Immunology, Hospital Gregorio Marañon, Madrid, Spain, 6Immuno-oncology, Hospital Gregorio Marañon, Madrid, Spain

    Background/Purpose: A novel population of CD4+ T cells with B cell helping capacity has been described in the synovial tissues and peripheral blood of seropositive…
  • Abstract Number: 1462 • ACR/ARHP Annual Meeting 2014

    Cadherin-11 mRNA Expression in the Peripheral Blood of Rheumatoid Arthritis Patients As a Marker of Active Polyarthritis

    Petros P. Sfikakis1, Panagiotis F. Christopoulos1,2, Aristeidis G. Vaiopoulos1,2, Kalliopi Fragkiadaki1, Christina Katsiari3, Violetta Kapsimali4, George Lallas1, Panayiotis Panayiotidis4, Pinelopi Korkopoulou5 and Michael Koutsilieris2, 1First Department of Propedeutic Internal Medicine, Laikon Hospital, Athens University Medical School, Athens, Greece, 2Department of Physiology, Athens University Medical School, Athens, Greece, 3Department of Rheumatology, School of Health Sciences, University of Thessaly, Larissa, Greece, 4Department of Microbiology, Athens University Medical School, Athens, Greece, 5Department of Pathology, Athens University Medical School, Athens, Greece

    Background/Purpose: Human rheumatoid arthritis synovial fibroblasts (RASF) implanted subcutaneously in immunodeficient mice trans-migrate through the vasculature and drive the progression from oligo- to poly-articular disease.…

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