Abstracts tagged "pain"

Abstract Number: 1650 • ACR Convergence 2020
A Double-Blind Randomized Trial to Evaluate the Efficacy of Corticosteroid Injections for Osteoarthritis of the Knee Using Mobile Devices
Joshua Baker¹, Mitesh Patel¹, Tuhina Neogi², Keith Robinson³, Alexis Ogdie¹ and Carla Scanzello¹, ¹University of Pennsylvania, Philadelphia, PA, ²Boston University School of Medicine, Boston, MA, ³Corporal Michael J Crescenz VA Medical Center, Philadelphia, PA
Background/Purpose: The value of intra-articular (IA) corticosteroid injections for osteoarthritis of the knee (KOA) has recently been called into question. Variability in clinical trial design…
Abstract Number: 1984 • ACR Convergence 2020
Causal Pathways to Health-Related Quality of Life in Children with Juvenile Idiopathic Arthritis: Results from the ReACCh-Out Cohort
Kiem Oen¹, Jiahao Tian², Thomas Loughin², Roberta Berard³, Mercedes Chan⁴, Ciaran Duffy⁵, Brian Feldman⁶, Adam Huber⁷, Deborah Levy⁸, Dax G. Rumsey⁹, Natalie Shiff¹⁰, Shirley Tse¹¹, Lori Tucker⁴, Karen Watanabe-Duffy⁵ and Jaime Guzman¹², ¹University of Manitoba, Toronto, ON, Canada, ²Simon Fraser University, Burnaby, BC, Canada, ³London Health Sciences Centre, London, ON, Canada, ⁴BC Children's Hospital, Vancouver, BC, Canada, ⁵Children's Hospital of Eastern Ontario, Ottawa, ON, Canada, ⁶The Hospital for Sick Children, Toronto, ON, Canada, ⁷Dalhousie University, Halifax, NS, Canada, ⁸Division of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, ⁹University of Alberta, Edmonton, AB, Canada, ¹⁰Florida, Gainesville, FL, ¹¹SickKids, Toronto, ON, Canada, ¹²University of British Columbia and BC Children's Hospital, Vancouver, BC, Canada
Background/Purpose: The relative roles of disease activity and disability as determinants of health-related quality of life (HRQoL) in children with JIA have been controversial; sometimes…
Abstract Number: 0022 • ACR Convergence 2020
Association Between Changes in Pain Sensitization and Changes in Disease Activity After 12 Weeks of Disease Modifying Anti-Rheumatic Drug Therapy in Rheumatoid Arthritis
Andrew Heisler¹, Jing Song², Lutfiyya Muhammad³, Alyssa Wohlfahrt⁴, Wendy Marder⁵, Marcy Bolster⁶, Clifton Bingham III⁷, Daniel Clauw⁸, Dorothy Dunlop⁹, Tuhina Neogi¹⁰ and Yvonne Lee³, ¹Northwestern University Feinberg School of Medicine, Oak Park, IL, ²Northwestern University, Chicago, ³Northwestern University Feinberg School of Medicine, Chicago, IL, ⁴Brigham and Womans Hospital, Boston, MA, ⁵University of Michigan, Ann Arbor, MI, ⁶Massachusetts General Hospital, Concord, MA, ⁷Johns Hopkins University, Baltimore, MD, ⁸Michigan Medicine, Ann Arbor, MI, ⁹Northwestern University, New Haven, CT, ¹⁰Boston University School of Medicine, Boston, MA
Background/Purpose: Patients with rheumatoid arthritis (RA) have abnormalities in central nervous system regulation of pain, leading to enhanced pain sensitivity at joint sites (peripheral sensitization)…
Abstract Number: 0542 • ACR Convergence 2020
Examining the Long-Term and Short-Term Day-To-Day Pain Variability in Inflammatory and Non-Inflammatory Rheumatic and Musculoskeletal Diseases Using Multilevel and Markov Transition Models: Cloudy with a Chance of Pain, a National U.K. Smartphone Study
Huai Leng Pisaniello¹, Mark Lunt², John McBeth³ and William Dixon², ¹University of Adelaide, Kidman Park, South Australia, Australia, ²Centre for Epidemiology Versus Arthritis, University of Manchester, Manchester, United Kingdom, ³University of Manchester, Manchester, United Kingdom
Background/Purpose: Chronic pain is common in rheumatic and musculoskeletal diseases (RMDs), yet the patterns and the extent of variability over time are poorly understood. Real-time…
Abstract Number: 0961 • ACR Convergence 2020
Development of a Pain Sensitivity Index to Examine the Transition from Intermittent to Constant Pain in Knee Osteoarthritis: The Multicenter Osteoarthritis Study
Kosaku Aoyagi¹, Lisa Carlesso², S. Reza Jafarzadeh¹, Michael LaValley³, Na Wang¹, Laura Frey Law⁴, Beth Lewis⁵, Michael Nevitt⁶ and Tuhina Neogi¹, ¹Boston University School of Medicine, Boston, MA, ²McMaster University, Hamilton, ON, Canada, ³Boston University School of Public Health, Boston, MA, ⁴University of Iowa, Iowa City, IA, ⁵University of Alabama at Birmingham, Birmingham, ⁶University of California, San Francisco, San Francisco, CA
Background/Purpose: Alterations in nociceptive signaling, such as pain sensitization, which is an abnormal ascending pain facilitation, and/or inadequate descending pain modulation, are thought to be…
Abstract Number: 1317 • ACR Convergence 2020
A Large Agreement Between the Pain Points of the ACR 1990 Fibromyalgia Criteria and the MASES Enthesitis Score Is Observed in Patients with Axial Spondylitis, Including in Patients Without Concomitant Fibromyalgia
Faten Hamitouche¹, Clementina Lopez-Medina², Laure Gossec³, Serge Perrot⁴, Maxime Dougados⁵ and Anna Molto⁶, ¹Rheumatology Department, Cochin Hospital, Paris, Ile-de-France, France, ²Rheumatology Department, Cochin Hospital, Paris, Paris, France, ³Sorbonne Université and Hôpital Universitaire Pitié Salpêtrière, Paris, France, ⁴Paris Descartes University, Paris, Ile-de-France, France, ⁵Université de Paris, Department of Rheumatology, Hôpital Cochin, Assistance Publique-Hôpitaux de Paris, Paris, France, ⁶Rheumatology Department, Cochin Hospital, APHP, Paris, France, Paris, France
Background/Purpose: Enthesitis is the hallmark lesion in Spondyloarthritis (SpA). The Maastricht Ankylosing Spondylitis Enthesitis score (MASES), which assesses 13 enthesitic sites, is the most widely…
Abstract Number: 1651 • ACR Convergence 2020
Efficacy and Safety of Multiple Intra-articular Corticosteroid Injections for Osteoarthritis – a Systematic Review and Meta-analysis of Randomised Controlled Trials and Observational Studies
Shazeen Ayub¹, Jaspreet Kaur¹, Michelle Hui², Michelle Hall¹, Michael Doherty³ and Weiya Zhang¹, ¹Academic Rheumatology, School of Medicine, University of Nottingham, UK, Nottingham, United Kingdom, ²Royal Derby Hospital, Derby, UK, Derby, United Kingdom, ³Academic Rheumatology, School of Medicine, University of Nottingham, UK, Nottingham, England, United Kingdom
Background/Purpose: Osteoarthritis (OA) is the most common form of arthritis worldwide and is becoming more prevalent with the increasing age of the population. As Intra-articular…
Abstract Number: 060 • 2020 Pediatric Rheumatology Symposium
Parsing Apart the Pain Experience: Exploring Treatment-Related Pain in Juvenile Idiopathic Arthritis
Yvonne Brandelli¹, Christine Chambers ², Perri Tutelman ¹, Jennifer Stinson ³, Adam Huber ⁴ and Jennifer Wilson ⁵, ¹Dalhousie University, Halifax, Nova Scotia, Canada, ²Dalhousie University & IWK Health Centre, Halifax, Nova Scotia, Canada, ³University of Toronto & The Hospital for Sick Children, Toronto, Ontario, Canada, ⁴IWK Health Centre & Dalhousie University, Halifax, Nova Scotia, Canada, ⁵Cassie and Friends, Vancouver, British Columbia, Canada
Background/Purpose: Pain is one of the most frequently reported symptoms among children with Juvenile Idiopathic Arthritis (JIA), and in recent decades our understanding and assessment…
Abstract Number: 097 • 2020 Pediatric Rheumatology Symposium
A Pilot Randomized Controlled Trial of the iCanCope Pain Self-management Application for Adolescents with Juvenile Idiopathic Arthritis
Chitra Lalloo ¹, Lauren Harris ², Amos Hundert ², Roberta Berard ³, Joseph Cafazzo ⁴, Mark Connelly ⁵, Brian Feldman ², Kristin Houghton ⁶, Adam Huber ⁷, Ronald Laxer ⁸, Nadia Luca ⁹, Heinrike Schmeling ¹⁰, Lynn Spiegel ¹¹, Lori Tucker ¹², Quynh Pham ⁴, Cleo Davies-Chalmers ¹³ and Jennifer Stinson¹⁴, ¹The Hospital for Sick Children, Toronto, Ontario, Canada, ²The Hospital for Sick Children, Toronto, Canada, ³Children's Hospital London Health Sciences Centre, London, Canada, ⁴University of Toronto, Toronto, Canada, ⁵Kansas City, ⁶University of British Columbia - Vancouver, Vancouver, Canada, ⁷IWK Health Centre & Dalhousie University, Halifax, Nova Scotia, Canada, ⁸The Hospital for Sick Children and University of Toronto, Toronto, Canada, ⁹University of Calgary, Calgary, Alberta, Canada, ¹⁰Alberta Children's Hospital/University of Calgary, Calgary, Alberta, Canada, ¹¹University of Toronto/Hospital for Sick Children, Thornhill, Canada, ¹²BC Children's Hospital, Vancouver, British Columbia, Canada, ¹³The Hospital for Sick Children, Toonto, Canada, ¹⁴University of Toronto & The Hospital for Sick Children, Toronto, Ontario, Canada
Background/Purpose: Pain is the most common symptom of Juvenile Idiopathic Arthritis (JIA), a chronic childhood illness that has potentially debilitating effects on health-related quality of…
Abstract Number: 110 • 2020 Pediatric Rheumatology Symposium
Consequences and Predictors of Persisting Pain in Children with Juvenile Idiopathic Arthritis: A Case Control Study Nested in the ReACCh-Out Cohort
Tara McGrath¹, Jaime Guzman ², Lori Tucker ³, Natalie Shiff ⁴, Maryna Yaskina ⁵, Susan Tupper ⁶ and Dax Rumsey ⁷, ¹University of British Columbia, Vancouver, Canada, ²University of British Columbia and BC Children's Hospital, Vancouver, Canada, ³BC Children's Hospital, Vancouver, British Columbia, Canada, ⁴Florida, Gainesville, ⁵Women and Children's Research Institute, Edmonton, Canada, ⁶Saskatoon, Canada, ⁷University of Alberta, Edmonton, Canada
Background/Purpose: Juvenile Idiopathic Arthritis (JIA) is the most common rheumatic disease of childhood. Pain is a distressing and prevalent feature of JIA and can decrease…
Abstract Number: 115 • 2020 Pediatric Rheumatology Symposium
Carbohydrate and Sugar Intake Predict Pain in Teens with Active JIA Disease but Not in Teens in Remission or Controls: A Cross-Sectional, Case-Control Metabolomics Pilot Study
Kimberly Lewis¹, Nico Osier ², Patricia Carter ³, Christina Nguyen ⁴, Ruy Carrasco ⁵, Shelby Brooks ², Alexandra Garcia ⁶ and Stefano Tiziani ⁵, ¹The University of Texas at Austin, Austin, Texas, ²The University of Texas at Austin, Austin, ³University of Alabama, Tuscalossa, ⁴Ascension Seton Nursing Research, Austin, ⁵The University of Texas at Austin, Dell Medical School, Austin, ⁶The University of Texas at Austin, Dell Medical School, School of Nursing, Austin
Background/Purpose: The purpose of this study is to define the relationships between pain and carbohydrate metabolism in teens with active juvenile idiopathic arthritis (JIA), teens…
Abstract Number: L03 • 2019 ACR/ARP Annual Meeting
NYX-2925 Impacts Functional and Chemical Neuroimaging Biomarkers and Patient-reported Outcomes of Pain in Patients with Fibromyalgia
Steven Harte ¹, Leslie Arnold ², Eric Ichesco ¹, Christopher Crumb ¹, Mary Suh ³, Laurel Sindelar ³, Chelsea Kaplan ¹, Tony Larkin ¹, Andrew Schrepf ¹, Daniel Clauw ⁴, Stephen Sainati ³ and Richard Harris¹, ¹University of Michigan, Ann Arbor, ²University of Cincinnati College of Medicine, Cincinnati, ³Aptinyx Inc, Evanston, ⁴Division of Rheumatology, Department of Internal Medicine and Division of Anesthesia, Michigan Medicine, Ann Arbor, MI
Background/Purpose: Fibromyalgia (FM) is a chronic, debilitating disease typified by widespread musculoskeletal pain and accompanied by fatigue, sleep disturbance, memory issues, and mood disorders. FM…
Abstract Number: 1216 • 2019 ACR/ARP Annual Meeting
Pilot, Randomized, Double-Blinded, Placebo Controlled Efficacy AndSafety Study of a Transdermal Alkalinizing and Pain Relieving Treatment ForAcute Gout Flare
Smitha Reddy¹, Ray Mabaquiao ² and Lisa Misell ³, ¹Arthritis Care and Research Inc., Poway, CA, ²Triwest Research, El Cajon, CA, ³Dyve Biosciences, San Diego, CA
Background/Purpose: Gout is characterized by a build-up of uric acid crystals in and around the joints. Uric acid crystal formation and dissolution is affected by…
Abstract Number: 1249 • 2019 ACR/ARP Annual Meeting
Pelvic Congestion Syndrome, an Uncommon Cause of Osteoarticular Pain
Mireia Castillo-Vilella¹, Jose Luis Tandaipan ², Laura Berbel ³, Lluís Moga ³, Georgina Salvador ³, Silvia Martínez-Pardo ³ and Nuria Giménez ³, ¹Hospital Universitari Sagrat Cor, Barcelona, Spain, ²Hospital Universitari Mutua Terrassa, Terrassa, Spain, ³Hospital Universitari Mútua Terrassa, Terrassa
Background/Purpose: Background: The pelvic congestion syndrome (PCS) is an under and often misdiagnosed entity that appears more frequently in premenopausal age and multiparous women. The…
Abstract Number: 1821 • 2019 ACR/ARP Annual Meeting
Tildrakizumab Efficacy for Psoriatic Arthritis: 24-week Analysis of Swollen and Tender Joint Counts and Pain
Ana-Maria Orbai ¹, Rocco Ballerini ², Richard C. Chou ³, Stephen Rozzo ², Alan Mendelsohn² and Luis R. Espinoza ⁴, ¹Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, ²Sun Pharmaceutical Industries, Inc., Princeton, NJ, USA, Princeton, NJ, ³University at Buffalo School of Medicine and Biomedical Sciences, Buffalo, NY, USA, Buffalo, NY, ⁴Section of Rheumatology, LSU Health Sciences Center, New Orleans, LA, New Orleans, LA
Background/Purpose: Tildrakizumab (TIL), a high-affinity anti–interleukin-23p19 monoclonal antibody, is approved to treat moderate-to-severe plaque psoriasis. A randomized, double-blind, multidose, placebo (PBO)-controlled, phase 2b study (NCT02980692)…

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