Abstracts tagged "pain"

Abstract Number: 2218 • 2016 ACR/ARHP Annual Meeting
Do Some Patients with Distal Upper Limb Pain Benefit More Than Others from Advice to Remain Active?
Daniel Whibley^1,2,3, Kathryn Remmes Martin^1,2,3, Karina Lovell⁴, Gary J. Macfarlane^1,2,3, Keith Palmer^5,6, David Coggon^5,6, Karen Walker-Bone^5,6, Kim Burton⁷, Peter Heine⁸, Candida McCabe^9,10, Paul McNamee¹¹, Alex McConnachie¹² and Gareth T. Jones^1,2,3, ¹Aberdeen Centre for Arthritis and Musculoskeletal Health, University of Aberdeen, Aberdeen, United Kingdom, ²Arthritis Research UK / MRC Centre for Musculoskeletal Health and Work, University of Aberdeen, Aberdeen, United Kingdom, ³Epidemiology Group, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, United Kingdom, ⁴School of Nursing, Midwifery and Social Work, University of Manchester, Manchester, United Kingdom, ⁵MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, United Kingdom, ⁶University of Southampton, Arthritis Research UK / MRC Centre for Musculoskeletal Health and Work, Southampton, United Kingdom, ⁷Centre for Health and Social Care Research, University of Huddersfield, Huddersfield, United Kingdom, ⁸Warwick Clinical Trials Unit, University of Warwick, Coventry, United Kingdom, ⁹University of West of England, Bristol, Bristol, United Kingdom, ¹⁰Royal United Hospitals NHS Foundation Trust, Bath, United Kingdom, ¹¹Health Economics Research Unit, University of Aberdeen, Aberdeen, United Kingdom, ¹²Robertson Centre for Biostatistics, University of Glasgow, Glasgow, United Kingdom
Background/Purpose: We have previously shown that, among patients awaiting physiotherapy for distal upper limb pain/disability, advice to remain active is associated with greater functional recovery…
Abstract Number: 2363 • 2016 ACR/ARHP Annual Meeting
Synovial Changes Detected By Ultrasound and Its Association with Knee Pain: A Population-Based Case Control Study
Aliya Sarmanova^1,2, Michelle Hall³, Gwen Fernandes^2,4,5, Archan Bhattacharya^1,6, Ana Valdes^1,2,5, David Walsh^2,5,7, Michael Doherty^2,4,5 and Weiya Zhang^2,4,5, ¹Division of Rheumatology, Orthopaedics and Dermatology, School of Medicine, University of Nottingham, the UK, Nottingham, United Kingdom, ²Arthritis Research UK Pain Centre, Nottingham, United Kingdom, ³School of Health Sciences, University of Nottingham, the UK, Nottingham, United Kingdom, ⁴Division of Rheumatology, Orthopaedics and Dermatology, School of Medicine, University of Nottingham, Nottingham, United Kingdom, ⁵Arthritis Research UK Centre for Sports, Exercise and Osteoarthritis, Nottingham, United Kingdom, ⁶Arthritis Research UK Centre for Sports, Exercise and Osteoarthritis, Nottignham, United Kingdom, ⁷Division of Rheumatology, Orthopaedics and Dermatology, School of Medicine, University of Nottingham, the UK, Nottignham, United Kingdom
Background/Purpose: To examine whether synovial changes on ultrasound (US) associate with knee pain (KP) and/or underlying structural radiographic changes of osteoarthritis (OA).Methods: In this case-control…
Abstract Number: 369 • 2016 ACR/ARHP Annual Meeting
Opioid Prescriptions and Adverse Reactions in Children and Adolescents without Serious Diseases
Cecilia P. Chung¹, S. Todd Callahan², William Cooper², William Dupont³, Katherine Murray¹, Kathi Hall⁴, Judith A. Dudley⁴, C. Michael Stein¹ and Wayne Ray⁴, ¹Medicine, Vanderbilt University Medical Center, Nashville, TN, ²Pediatrics, Vanderbilt University Medical Center, Nashville, TN, ³Biostatistics, Vanderbilt University Medical Center, Nashville, TN, ⁴Health Policy, Vanderbilt University Medical Center, Nashville, TN
Background/Purpose: There is a well-described epidemic of deaths and hospitalizations related to opioid prescriptions in adults. However, little is known about opioid toxicity in children.…
Abstract Number: 1783 • 2015 ACR/ARHP Annual Meeting
Dietary Fish Oil Supplementation Raises Serum Essential Fatty Acid Concentrations in Patients with Systemic Lupus Erythematosus and Correlates with Improvements in Inflammation and Pain
Cristina Arriens¹, Carlos Rodriguez-Navas², David R. Karp¹, Jeffrey McDonald² and Chandra Mohan³, ¹Internal Medicine - Rheumatic Diseases, University of Texas Southwestern Medical Center, Dallas, TX, ²Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX, ³Biomedical Engineering, University of Houston, Houston, TX
Background/Purpose: A comprehensive metabolomic screen comparing sera from patients with systemic lupus erythematosus (SLE) to healthy controls (HC) indicated a relative deficiency in omega-3 fatty…
Abstract Number: 2116 • 2015 ACR/ARHP Annual Meeting
Advice to Remain Active While Awaiting Physiotherapy Is Associated with Superior Long-Term Outcome Among Patients with Distal Arm Pain – Results from a Randomised Controlled Trial
Gareth T Jones^1,2, Gary J. Macfarlane^1,2, Keith Palmer^3,4, David Coggon^3,4, Karen Walker-Bone^3,4, Kim Burton⁵, Peter Heine⁶, Candida McCabe^7,8, Paul McNamee⁹ and Alex McConnachie¹⁰, ¹Musculoskeletal Research Collaboration (Epidemiology Group), University of Aberdeen, Aberdeen, United Kingdom, ²University of Aberdeen, Arthritis Research UK / MRC Centre for Musculoskeletal Health and Work, Aberdeen, United Kingdom, ³MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, United Kingdom, ⁴University of Southampton, Arthritis Research UK / MRC Centre for Musculoskeletal Health and Work, Southampton, United Kingdom, ⁵Centre for Applied Psychological and Health Research, University of Huddersfield, Huddersfield, United Kingdom, ⁶Warwick Clinical Trials Unit, University of Warwick, Coventry, United Kingdom, ⁷Nursing and Midwifery, University of the West of England, Bristol, United Kingdom, ⁸Royal United Hospital NHS Foundation Trust, Bath, United Kingdom, ⁹Health Economics Research Unit, University of Aberdeen, Aberdeen, United Kingdom, ¹⁰Robertson Centre for Biostatistics, University of Glasgow, Glasgow, United Kingdom
Background/Purpose: Pain in the distal upper limb (elbow, forearm, wrist or hand) is common, yet the best approach to management is unclear. While the etiological…
Abstract Number: 2278 • 2015 ACR/ARHP Annual Meeting
Identification of Long-Term Physical Activity Trajectories in Individuals with Chronic Widespread Pain Who Received Exercise Treatment As Part of a Randomized Controlled Trial
Kathryn Remmes Martin¹, Katie L. Druce¹, Lucia D'Ambruoso² and Gary J. Macfarlane¹, ¹Musculoskeletal Research Collaboration (Epidemiology Group), University of Aberdeen, Aberdeen, United Kingdom, ²Division of Applied Health Sciences, University of Aberdeen, Aberdeen, United Kingdom
Background/Purpose: For individuals living with chronic widespread pain (CWP), physical activity (PA) can be an effective non-pharmacological therapy for symptom management. PA Interventions may enhance…
Abstract Number: 26 • 2015 ACR/ARHP Annual Meeting
Higher Scores of Women Compared to Men for Most Clinical Measures of Rheumatoid Arthritis (RA) Status: Greater Differences for Patient Self-Report Scores Than for Rheumatologist Estimates: A Cross-Sectional 3 Center Study from Routine Care
Isabel Castrejón¹, Martin Bergman², Yusuf Yazici³, Annie Huang¹, Joel A. Block¹ and Theodore Pincus¹, ¹Rheumatology, Rush University Medical Center, Chicago, IL, ²Division of Rheumatology, Taylor Hospital, Ridley Park, PA, ³NYU Hospital for Joint Diseases, New York, NY
Background/Purpose: Higher scores for women compared to men have been reported for all 7 rheumatoid arthritis (RA) Core Data Set measures (1, 2). Most of…
Abstract Number: 2279 • 2015 ACR/ARHP Annual Meeting
Impacts on Work: Arthritis Vs Chronic Joint Symptoms without Arthritis
Kristina A. Theis and Michael Boring, Arthritis Program, Centers for Disease Control and Prevention, Atlanta, GA
Background/Purpose: While chronic joint symptoms are characteristic of arthritis, previous studies have shown that many people with chronic joint symptoms do not have doctor-diagnosed arthritis.…
Abstract Number: 64 • 2015 ACR/ARHP Annual Meeting
Nociceptive Flexion Reflex Threshold: Possible Surrogate Marker of Symptom Severity in Fibromyalgia
Dennis Ang¹, Christopher France² and James Slaven³, ¹Section on Rheumatology and Immunology, Wake Forest University, Winston Salem, NC, ²Psychology, Ohio University, Athens, OH, ³Biostatistics, Indiana University, Indianapolis, IN
Background/Purpose: Central sensitization has been demonstrated in patients with fibromyalgia (FM) using an objective assessment of spinal nociception called the nociceptive flexion reflex (NFR). This…
Abstract Number: 2307 • 2015 ACR/ARHP Annual Meeting
Relationship of Sleep Quality and Fibromyalgia Outcomes in a Phase 2b Randomized, Double-Blind, Placebo-Controlled Study of Bedtime, Rapidly Absorbed, Sublingual Cyclobenzaprine (TNX-102 SL)
Harvey Moldofsky¹, R Michael Gendreau², Daniel J. Clauw³, Judith Gendreau⁴, Benjamin Vaughn⁵, Bruce Daugherty⁴, Amy Forst⁶, Gregory Sullivan⁷ and Seth Lederman⁸, ¹Ctr for Sleep & Chronobiology, Centre for Sleep/Chronobiology, Toronto, ON, Canada, ²Gendreau Consulting LLC, Poway, CA, ³Anesthesiology, University of Michigan, Ann Arbor, MI, ⁴Tonix Pharmaceuticals, New York, NY, ⁵Statistics, Rho, Chapel Hill, NC, ⁶Clinical Development, Tonix Pharmaceuticals, San Jose, CA, ⁷Clinical Development, Tonix Pharmaceuticals, NEW YORK, NY, ⁸Research and Development, Tonix Pharmaceuticals, Inc., New York, NY
Background/Purpose: The importance of nonrestorative sleep in the pathophysiology of fibromyalgia (FM) suggests that treatments that improve sleep quality would address global symptoms. TNX-102 SL1a…
Abstract Number: 70 • 2015 ACR/ARHP Annual Meeting
Data from Brazilian Fibromyalgia Patients Registry (EPIFIBRO) in 2014
Jose Eduardo Martinez^1,2, Marcelo C. Rezende^3,4, Eduardo Paiva^4,5, Daniel Pollak^4,6, Milton Helfenstein Jr^4,7, Jose Roberto Provenza^4,8, Aline Ranzolin^4,9, Roberto E Heymann^4,10, Eduardo L. Ribeiro^4,11, Marcos Renato Assis^4,12 and Eduardo J. R. Souza^4,13, ¹Sociedade Brasileira de Reumatologia, Sorocaba, Brazil, ²Medicine, Pontifical Catholic University of Sao Paulo, Sorocaba, Brazil, ³Santa Casa de Campo Grande, Campo Grande, Brazil, ⁴Sociedade Brasileira de Reumatologia, São Paulo, Brazil, ⁵Rheumatology, Universidade Federal do Parana, Curitiba, Brazil, ⁶Rheumathology, Universidade Federal de São Paulo, São Paulo, Brazil, ⁷RUA JOAO DE LACERDA SOARES, 90, Unifesp, Sao Paulo, Brazil, ⁸Rheumatology, Pontifícia Universidade Católica de Campinas, Campinas, Brazil, ⁹Hospital das Clínicas - Universidade Federal de Pernambuco, Recife, Brazil, ¹⁰Universidade Federal de São Paulo, São Paulo, Brazil, ¹¹Instituto de Previdência dos Servidores do Estado de Minas Gerais, Belo Horizonte, Brazil, ¹²Faculdade de Medicina de Marilia, Marilia, Brazil, ¹³Santa Casa de Belo Horizonte, Belo Horizonte, Brazil
Background/Purpose: –The Brazilian registry on fibromyalgia syndrome (EPIFIBRO) included 810 patients who satisfied the American College of Rheumatology Classification Criteria for Fibromyalgia (ACR1990) at the…
Abstract Number: 2308 • 2015 ACR/ARHP Annual Meeting
Responder Compared to Mean Change Analyses in a Fibromyalgia Phase 2b Clinical Study of Bedtime Rapidly Absorbed Sublingual Cyclobenzaprine (TNX-102 SL)
R Michael Gendreau¹, Daniel J. Clauw², Judith Gendreau³, Bruce Daugherty³ and Seth Lederman⁴, ¹Gendreau Consulting LLC, Poway, CA, ²Anesthesiology, University of Michigan, Ann Arbor, MI, ³Tonix Pharmaceuticals, New York, NY, ⁴Research and Development, Tonix Pharmaceuticals, Inc., New York, NY
Background/Purpose: Fibromyalgia (FM) is characterized by symptoms that include widespread pain and sleep disruption. Clinical studies that rely on patient self-reported outcome measures such as pain…
Abstract Number: 388 • 2015 ACR/ARHP Annual Meeting
Pain, Fatigue and the Psychological Impact on Health-Related Quality of Life in Childhood-Onset Lupus
Jordan T. Jones¹, Natoshia Cunningham², Catherine Donnelly³, Susmita Kashikar-Zuck⁴ and Hermine I. Brunner⁵, ¹Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²Behavioral Medicine & Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ³Internal Medicine, University of Cincinnati, Cincinnati, OH, ⁴Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁵Pediatric Rheumatology Collaborative Study Group, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
Background/Purpose: Childhood-onset lupus (cSLE) is a chronic autoimmune disease that has negative impact on health-related quality of life (HRQoL), especially when increased disease activity and…
Abstract Number: 2309 • 2015 ACR/ARHP Annual Meeting
Bedtime, Rapidly Absorbed Sublingual Cyclobenzaprine (TNX-102 SL) for the Treatment of Fibromyalgia: Results of a Phase 2b Randomized, Double-Blind, Placebo-Controlled Study
Seth Lederman¹, R Michael Gendreau², Daniel J. Clauw³, Lesley M. Arnold⁴, Judith Gendreau⁵, Bruce Daugherty⁵ and Amy Forst⁶, ¹Research and Development, Tonix Pharmaceuticals, Inc., New York, NY, ²Gendreau Consulting LLC, Poway, CA, ³Anesthesiology, University of Michigan, Ann Arbor, MI, ⁴Psychiatry, University of Cincinnati, Cincinnati, OH, ⁵Tonix Pharmaceuticals, New York, NY, ⁶Clinical Development, Tonix Pharmaceuticals, San Jose, CA
Background/Purpose: Fibromyalgia (FM) is characterized by chronic widespread pain and sleep disturbance. Treatments that improve sleep quality in FM patients may improve fibromyalgia by a…
Abstract Number: 417 • 2015 ACR/ARHP Annual Meeting
Gender Differences in Pediatric Localized Scleroderma: Clinical and Patient-Reported Outcomes
Kaveh Ardalan¹, Nicole Hershey¹, Jonathan Yabes², Eveline Wu³, Suzanne C. Li⁴, Robert C. Fuhlbrigge⁵, C. Egla Rabinovich⁶, Kathryn S. Torok¹ and The CARRA Registry Investigators, ¹Pediatric Rheumatology, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, ²Department of Medicine, University of Pittsburgh, Pittsburgh, PA, ³Pediatrics, University of North Carolina - Chapel Hill, Chapel Hill, NC, ⁴Pediatrics, Joseph M Sanzari Children’s Hospital, Hackensack University Medical Center, Hackensack, NJ, ⁵Program in Rheumatology, Division of Immunology, Boston Children’s Hospital, Boston, MA, ⁶Pediatric Rheumatology, Duke University Medical Center, Durham, NC
Background/Purpose: Localized scleroderma (LS) is an autoimmune disease of the skin and underlying tissue that leads to progressive fibrosis and disability in growing children. Pediatric…

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