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Abstracts tagged "pain"

  • Abstract Number: 2342 • ACR Convergence 2025

    Real-World Effectiveness and Satisfaction in Biologic-Naïve Patients With Psoriatic Arthritis and Limited Joint Involvement Treated With Risankizumab in the United States and Europe

    Andrew Ostor1, Jessica A. Walsh2, Christopher Saffore3, Xiaolan Ye4, Manish Patel5, Ana Biljan6, Jamie Vora7, Isabel Truman8, Molly Edwards8, Gary Milligan8 and William Tillett9, 1Australian National University, Canberra, Australia, 2Division of Rheumatology, Salt Lake City Veterans Affairs Health and University of Utah Health, Salt Lake City, UT, 3AbbVie Inc., waukegan, IL, 4AbbVie Inc., Mettawa, IL, 5AbbVie Inc., North Chicago, IL, 6AbbVie Inc., Buffalo Grove, IL, 7AbbVie Inc., Palatine, IL, 8Adelphi Real World, Bollington, United Kingdom, 9Department of Life Sciences, Centre for Therapeutic Innovation, University of Bath, Bath, United Kingdom

    Background/Purpose: This study evaluated real-world effectiveness and patient- and physician-satisfaction with risankizumab (RZB) for biologic-naïve PsA patients with limited joint involvement or oligoarthritis.Methods: Data were…
  • Abstract Number: 2065 • ACR Convergence 2025

    Pain in Idiopathic Inflammatory Myopathies: A Global Study of Patient Experience

    Lekshmi Minikumari Rahulan1, Shounak Ghosh2, Manali Sarkar3, Didem Saygin4, Karin Lodin5, Rima Shrestha6, Tulika Chatterjee7, Jessica Day8, Samuel Shinjo9, Sreoshy Saha10, Lorenzo Cavagna11, Masataka Kuwana12, Vikas Agarwal13 and Latika Gupta14, 1Sanjay Gandhi Postgraduate Institute of Medical sciences Lucknow, Lucknow, Uttar Pradesh, India, 2Department of Rheumatology, The Royal Wolverhampton NHS Trust, Wolverhampton, UK, Wolverhampton, United Kingdom, 3Sir H. N. Reliance Foundation Hospital and Research Centre, Mumbai, Maharashtra, India., Mumbai, Maharashtra, India, 4Rush University Medical Center, Chicago, IL, 5Department of Gastro, Dermatology and Rheumatology, Karolinska University Hospital, Stockholm, Sweden, Division of Rheumatology, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden, Stockholm, Sweden, 6Department of Internal Medicine, University of Illinois College of Medicine Peoria, Illinois, United States, Department of Research Services, University of Illinois College of Medicine Peoria, Illinois, United States, Illinois, 7Department of Internal Medicine, University of Illinois College of Medicine Peoria, Illinois, United States, Illinois, 8Walter and Eliza Hall Institute, Melbourne, Victoria, Australia, 9Division of Rheumatology, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, Brazil, Sao Paulo, Brazil, 10Mymensingh Medical College, Mymensingh, Bangladesh, Mymensingh, Bangladesh, 11Associate Professor in Rheumatology (Internal Medicine and Thepaeutics),University of Pavia, Pavia, Lombardy, Italy, Physician in Chief of Myositis Outpatients Clinic,Fondazione IRCCS Policlinico San Matteo, Pavia, Lombardia,Italy, Lombardia, Italy, 12Nippon Medical School Graduate School of Medicine, Tokyo, Japan, 13Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India, 14School of Infection, Inflammation and Immunology, College of Medicine and Health, University of Birmingham; Royal Wolverhampton NHS Trust; Centre for Musculoskeletal Research, School of Biological Sciences, The University of Manchester, Manchester; Francis Crick Institute, London, Birmingham, UK, United Kingdom

    Background/Purpose: Pain remains a significant yet understudied aspect of idiopathic inflammatory myopathies (IIMs), considerably reducing quality of life despite advancements in immunomodulatory therapies. Information obtained…
  • Abstract Number: 1487 • ACR Convergence 2025

    Whole Health Empowerment for Endotypes of Lupus (WHEEL) Program: User Testing Findings on Feasibility, Acceptability, and Opportunities for Intervention Refinement

    Jennifer Rogers1, Amanda Eudy2, Connor Drake3, Tamara Somers4, David Pisetsky5, Christie Clipper6, Ralph Snyderman7, Anna Batsakes6, Leigh Saner6, Dana Burshell3, Mithu Maheswaranathan4, Lisa Criscione-Schreiber4, Rebecca Sadun8, Nathaniel Harris5, Kai Sun8, Kelsey Dunn6, Jenny Herndon6, Vonne Jacobs6 and Megan Clowse9, 1Duke, Durham, NC, 2Duke University, Raleigh, NC, 3Duke University School of Medicine, Durham, 4Duke University School of Medicine, Durham, NC, 5Duke University Medical Center, Durham, NC, 6Duke University, Durham, 7Duke Center for Personalized Health Care, Durham, NC, 8Duke University, Durham, NC, 9Duke University, Chapel Hill, NC

    Background/Purpose: To improve quality of life (QoL) in individuals with SLE, we developed the Whole Health Empowerment for Endotypes of Lupus (WHEEL) program—a 4-month, biweekly,…
  • Abstract Number: 1239 • ACR Convergence 2025

    JAK inhibition appears to alter clinical and neurobiological markers of nociplastic pain in rheumatoid arthritis: a 7T MRI Brain study

    Kristian Stefanov1, Andrew McGucken1, Maxine Arnott1, Tyrone Lau1, Norah Aldehmi1, Vinod Kumar2, Neil McKay3, James Dale4, Lindsay Robertson5, James Brock1, Flavia Sunzini6 and Neil Basu7, 1University of Glasgow, Glasgow, United Kingdom, 2NHS Tayside, Dundee, United Kingdom, 3NHS Lothian, Edinburgh, United Kingdom, 4NHS Lanarkshire, Wishaw, United Kingdom, 5NHS Grampian, Aberdeen, United Kingdom, 6Glasgow University, Glasgow, United Kingdom, 7Institute of Infection, Immunity & Inflammation, University of Glasgow, Glasgow, United Kingdom

    Background/Purpose: Pain remains a prevalent and highly impactful issue for people with rheumatoid arthritis (RA). Among modern day targeted therapies, the janus kinase (JAK) inhibitors…
  • Abstract Number: 1196 • ACR Convergence 2025

    Prevalence of and Factors Associated with Chronic Opioid Use among Individuals with Inflammatory Myopathies

    Anuya Natu1, Haley Zimmerman2, Kristin Wipfler3, Kaleb Michaud4, Yvonne Lee5 and Didem Saygin2, 1John H. Stroger, Jr. Hospital of Cook County, Chicago, IL, 2Rush University Medical Center, Chicago, IL, 3FORWARD, The National Databank for Rheumatic Diseases, Omaha, NE, 4University of Nebraska Medical Center, Omaha, NE, 5Northwestern University, Chicago, IL

    Background/Purpose: Idiopathic inflammatory myopathies (IIM) can be associated with significant pain and functional impairment. While the use of opioids has been documented in other inflammatory…
  • Abstract Number: 0503 • ACR Convergence 2025

    Impact of Olokizumab on Pain in Rheumatoid Arthritis: a Meta-analysis

    Andrey E. Karateev1, Sofia Kuzkina2, Alina Egorova3 and Elena Y. Polishchuk1, 1V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia, 2R-Pharm, Moscow, Russia, 3R-Pharm JSC, Moscow, Russia

    Background/Purpose: Pain is one of the most debilitating symptoms of rheumatoid arthritis (RA) and a major contributor to reduced quality of life. Persistent joint pain…
  • Abstract Number: 0292 • ACR Convergence 2025

    Patterns and Predictors of Longitudinal Trajectories of Pain in Individuals with Inflammatory Myopathies

    Haley Zimmerman1, Ethan Ritz2, Kristin Wipfler3, Kaleb Michaud4 and Didem Saygin1, 1Rush University Medical Center, Chicago, IL, 2Rush Research Informatics Core, Rush University Medical Center, Chicago, IL, 3FORWARD, The National Databank for Rheumatic Diseases, Omaha, NE, 4University of Nebraska Medical Center, Omaha, NE

    Background/Purpose: Idiopathic inflammatory myopathies (IIM) have historically been considered a disease of painless weakness. However, recent studies indicate that most patients with IIM experience pain…
  • Abstract Number: 2327 • ACR Convergence 2025

    Persistent Pain in PsA: A Distinct Phenotype of Depression, Fatigue, And Catastrophizing

    Rebecca Haberman1, Kyra Chen2, Adamary Felipe3, Stephanie Eichman3, Uma Scher4 and Jose Scher5, 1NYU Langone Health, New York, NY, 2NYU Grossman School of Medicine and NYU Langone Health Psoriatic Arthritis Center, New York, 3NYU Grossman School of Medicine, New York, 4NYU School of Medicine, Scarsdale, NY, 5New York University School of Medicine, New York, NY

    Background/Purpose: Targeted synthetic and biologic DMARDs have transformed psoriatic arthritis (PsA) treatment. Still, a substantial subset of patients reports persistent joint pain despite well-controlled inflammation.…
  • Abstract Number: 1987 • ACR Convergence 2025

    Evaluating User Engagement and Real-World Impact of a PMR-Specific Digital Symptom Assessment Tool: A 12-Month Analysis of PainSpot™

    Shilpa Venkatachalam1, Erik Stone2, Ian Carroll3, angela Degrassi3, Shelley Fritz4 and David Curtis5, 1Global Healthy Living Foundation, New York, NY, 2Global Healthy Living Foundation, Nyack, NY, 3Global Healthy Living Foundation, Upper Nyack, NY, 4Global Healthy Living Foundation, Kalaheo, HI, 5Global Healthy Living Foundation, Meriden

    Background/Purpose: Polymyalgia rheumatica (PMR) is a systemic inflammatory condition affecting individuals over 50, marked by bilateral shoulder and hip stiffness and pain. Its nonspecific symptoms…
  • Abstract Number: 1461 • ACR Convergence 2025

    Digital Behavioral Therapy Improves Outcome in Patients With Axial Spondyloarthritis And Persistent Pain: Results From a Randomized Controlled Trial

    David Kiefer1, Yade Sonkaya2, Dietmar Krause3, Markus Voglau4, Bernhard Mintrop5, Imke Redeker6, Xenofon Baraliakos7 and Uta Kiltz7, 1Ruhr-Universität Bochum; Private practice of rheumatology, Hattingen, Germany, Herne, Germany, 2Ruhr-Universität Bochum, Herne, Germany, 3Elisabeth-Gruppe, Herne, Germany, Essen, Germany, 4myself, Oldenburg, Germany, 5Private rheumatology practice, Hattingen, Germany, 6Ruhr University Bochum, Bochum, Germany, 7Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany

    Background/Purpose: Axial spondyloarthritis (axSpA) is often associated with persistent pain despite effective anti-inflammatory treatment, substantially impacting patients' quality of life. Digital health applications (DiGAs) provide…
  • Abstract Number: 1238 • ACR Convergence 2025

    Pain Is Associated with An Increased Risk of Frailty in Veterans with Rheumatoid Arthritis

    Nadine El-ayache1, Sayuli Bhide2, Hannah Brubeck3, Punyasha Roul4, Bryant England5, Joshua Baker6, Grant Cannon7, Namrata Singh8, Gary Kunkel9, Ted Mikuls5, Patti Katz10, Dolores Shoback11, Jose Garcia12, Pradeep Suri13, Marianna Gasperi13, Ariela Orkaby14, Una Makris15 and Katherine Wysham16, 1VA Puget Sound Health Care System & University of Washington, Seattle, WA, 2University of Washington, Seattle, WA, 3VA Puget Sound Health Care System, Seattle, WA, 4UNMC, Omaha, NE, 5University of Nebraska Medical Center, Omaha, NE, 6University of Pennsylvania, Philadelphia, PA, 7University of Utah and Salt Lake City VA, Salt Lake City, UT, 8University of Washington, Bellevue, WA, 9University of Utah and George E Wahlen VAMC, Salt Lake City, UT, 10UCSF, San Rafael, CA, 11San Francisco VA Medical Center & University of California San Francisco, San Francisco, CA, 12VA Puget Sound Health Care System, VA GRECC, and University of Washington, Seattle, WA, 13VA PUGET SOUND/UNIVERSITY OF WASHINGTON, Seattle, 14VA Boston Healthcare System & Division of Aging, Brigham and Women’s Hospital, Harvard Medical School & VA Geriatrics Research Education and Clinical Center, Boston, MA, 15UT Southwestern Medical Center and Dallas VA, Dallas, TX, 16VA PUGET SOUND/UNIVERSITY OF WASHINGTON, Seattle, WA

    Background/Purpose: Frailty, an increased vulnerability to stressors, is commonly associated with aging and functional decline. Pain, prevalent among older adults, contributes to frailty in the…
  • Abstract Number: 1149 • ACR Convergence 2025

    Patient Symptom State Demonstrates Validity for the Assessment of Disease Activity and Patient-reported Outcomes in Adults with SAPHO and Chronic Nonbacterial Osteomyelitis – A Longitudinal Response Profile Analysis in The SAPHO-CNO Study

    Aleksander Lenert1, Robyn Domsic2, Jenna Thomason3, Melanie smith4, Petar Lenert5, Yongdong (Dan) Zhao6, Jonathan Templin1, Mary Vaughan-Sarrazin1, Daniel Solomon7 and Polly Ferguson8, 1University of Iowa, Iowa City, IA, 2University of Pittsburgh, Pittsburgh, PA, 3University of Washington, Seattle, WA, 4Hospital for Special Surgery, Weill Cornell Medicine, New York, NY, 5University of Iowa Hospitals and Clinics, Iowa City, IA, 6Seattle Children’s Research Institute, Redmond, WA, 7Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Boston, MA, 8University of Iowa Carver College of Medicine, Iowa City, IA

    Background/Purpose: Patient symptoms are important in the assessment of disease activity. The Patient Acceptable Symptom State (PASS) is defined as the minimum symptom score beyond…
  • Abstract Number: 0492 • ACR Convergence 2025

    Outcomes of Total Knee Replacement in Patients with Rheumatoid Arthritis: A National Inpatient Sample Database Analysis

    karun Shrestha1, Pravakar Parajuli2, Anil Regmi3, Prakriti Subedi4, Manoj Ghimire5, Sajana Poudel6, Mohammed Hasan7, Mahmoud Hashim8, Veera Durga Vaishnavi Kurra9 and ClementT Taoge10, 1Department of Internal Medicine, St. Barnabas Hospital, SBH Health System, Bronx, NY 10457, USA, BRONX, NY, 2Patan Academy of Health Sciences-School of Medicine (PAHS-SOM), Lalitpur, Bagmati, Nepal, 3Parkview Health, Fort Wayne, IN, 4St. Barnabas Hospital, Bronx, NY, 5St Barnabas Hospital, BRONX, NY, 6Cook County Health, CHICAGO, NY, 7Parkview Medical Center, Pueblo, CO, 8SBH Health System, New Rochelle, NY, 9University of Oklahoma Health Sciences Center, Oklahoma City, OK, 10Albert Einstein College of Medicine - Montefiore Medical Center, Bronx

    Background/Purpose: Rheumatoid arthritis (RA) is a chronic, inflammatory disease of the joints with an estimated prevalence of 0.5% of people. Nearly 25% of RA patients…
  • Abstract Number: 0199 • ACR Convergence 2025

    Pain Phenotypes and Social Determinants of Health in Chronic Chikungunya Arthritis: A Cross-Sectional Study

    Abebawork Adem1, Alfonso Sucerquia2, Jose Forero3, Juan Alzate2, Larry Moreland4, Gary Firestein5, Andres Cadena6 and Aileen Chang7, 1George Washington University, Washington, DC, DC, 2The George Washington University, Arlington, 3The George Washington University, Arlington, VA, 4University of Colorado, Denver, CO, 5University of California, San Diego, San Diego, CA, 6Clinica de la Costa, Barranquilla, Colombia, 7The George Washington University, Washington

    Background/Purpose: Chronic chikungunya arthritis (CCA) is a long-term sequela of chikungunya virus infection marked by persistent pain, disability, and reduced quality of life. While nociplastic,…
  • Abstract Number: 2320 • ACR Convergence 2025

    Sleep Disturbance in Psoriatic Arthritis: Prevalence by Minimal Disease Activity Status and Associated Clinical Factors

    Lourdes Perez Chada1, Vivi Feather2, Grace Carter2, Helen Early3, Emily Tsai2, Jing Cui4, Avery LaChance5, Rochelle Castillo6, Neda shahriari2, Alexis Ogdie7, Monika Haack2, Elizabeth Klerman2, Michael Weinblatt8, Nancy Shadick9, Joseph Merola10 and Chinmayi Naik3, 1Harvard Medical School, Wayland, MA, 2Mass General Brigham, Boston, MA, 3Brigham and Women's Hospital, Boston, MA, 4Brigham Women's Hospital, Boston, MA, 5Brigham and Women's Hospital, Jamaica Plain, MA, 6Brigham and Women's Hospital, Brookline, MA, 7Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Wilmington, DE, 8Brigham and Women's Hospital/ Harvard Medical School, Waban, MA, 9Brigham & Women's Hospital, Boston, MA, 10UT Southwestern Medical Center, Dallas, TX

    Background/Purpose: Sleep disturbance is a common and burdensome symptom in psoriatic arthritis (PsA), but its clinical determinants remain poorly understood. Using data from the Cohort…
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