Abstracts tagged "pain"

Abstract Number: 1660 • ACR Convergence 2020
Sleep Disturbance and Pain Severity and Multi-site Pain: A Prospective 10.7-year Follow-up Study
Feng Pan¹, Jing Tian¹, Flavia Cicuttini² and Graeme Jones¹, ¹University of Tasmania Menzies Institute for Medical Research, Hobart, Tasmania, Australia, ²Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia
Background/Purpose: Sleep disturbance is often comorbid with chronic pain disorders, with emerging evidence suggesting a stronger effect of sleep disturbance on pain than vice versa;…
Abstract Number: 0096 • ACR Convergence 2020
The Bicipital Stress Test: A Maneuver to More Accurately Diagnose Bicipital Tendinitis and Its Referred Pain Patterns
Meredith Thomley¹, David Spalding², Ana Preda-Naumescu¹ and Raymond Waldrop¹, ¹University of Alabama at Birmingham, Birmingham, ²University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: Inflammation of the bicipital tendon contributes heavily to shoulder joint morbidity. To date, diagnosis of bicipital tendinitis has relied on physical exam findings, particularly…
Abstract Number: 0565 • ACR Convergence 2020
In Those with Unilateral Frequent Knee Pain, Between-Limb Differences in Stance Time During Walking Increase the Risk of Frequent Pain in the Other Knee: The MOST Study
Patrick Corrigan¹, David Felson², Cara Lewis³, K. Douglas Gross⁴, Michael Nevitt⁵, Beth Lewis⁶, James Torner⁷ and Joshua Stefanik¹, ¹Northeastern University, Boston, MA, ²Boston University School of Medicine, Boston, MA, ³Boston University, Brookline, MA, ⁴MGH Institute of Health Professionals, Boston, MA, ⁵Department of Epidemiology and Biostatistics, University of California San Francisco, Orinda, CA, ⁶University of Alabama at Birmingham, Birmingham, ⁷University of Iowa, Iowa City, IA
Background/Purpose: Knee osteoarthritis (OA) commonly begins as a unilateral disease, with pain in only one knee. Yet 88% of persons with unilateral knee OA develop…
Abstract Number: 1102 • ACR Convergence 2020
Neuropathic Pain in Inflammatory Hand Osteoarthritis(OA) Lowers Quality of Life and May Require Another Approach Than Anti-inflammatory Treatment
Coen van der Meulen¹, Lotte van de Stadt¹, Féline Kroon², Marion Kortekaas¹, Annelies Boonen³, Stefan Böhringer⁴, Monique Reijnierse², Frits Rosendaal², Naghmeh Riyazi⁵, Mirian Starmans⁶, Franktien Turkstra⁷, Jende Van Zeben⁸, CF Allaart² and Margreet Kloppenburg², ¹LUMC, Leiden, Netherlands, ²Leiden University Medical Center, Leiden, Netherlands, ³Maastricht University Medical Center, Maastricht, Netherlands, ⁴LUMC, Leiden, ⁵HAGA ziekenhuis, the hague, Netherlands, ⁶Zuyderland MC, Heerlen, Netherlands, ⁷Reade, Amsterdam, Netherlands, ⁸Franciscus Gasthuis & Vlietland, Rotterdam, Netherlands
Background/Purpose: To investigate whether neuropathic pain is present in patients with inflammatory hand OA, to investigate characteristics of those patients and the impact of neuropathic…
Abstract Number: 1484 • ACR Convergence 2020
Efficacy of Tocilizumab in Patients with Hand Osteoarthritis: Double Blind, Randomized, Placebo Controlled, Multicenter Trial
Pascal Richette¹, Augustin Latourte², Jeremie Sellam³, Daniel Wendling⁴, Muriel Piperno⁵, Philippe Goupille⁶, Yves-Marie Pers⁷, Florent Eymard⁸, Sebastien Ottaviani⁹, Paul Ornetti¹⁰, Rene-Marc Flipo¹¹, Bruno Fautrel¹², Jean-Pierre Bertola¹³, Eric Vicaut¹⁴ and Xavier Chevalier¹⁵, ¹Department of Rheumatology, Lariboisière Hospital, AP-HP Université de Paris, INSERM U1132, Paris, ²Department of Rheumatology, Lariboisière Hospital, AP-HP Université de Paris, INSERM U1132, Paris, France, ³AP-HP, Hôpital Saint-Antoine, Service de Rhumatologie, Centre de Recherche Saint-Antoine, INSERM UMR_S 938,Sorbonne Université, Paris, 75012, France, Paris, France, ⁴CHU Besançon, department of rheumatology, Besancon, France, ⁵Rheumatology Department, Lyon University Hospital, Lyon, France, ⁶CHU Tours, department of rheumatology, Tours, France, ⁷IRMB, University of Montpellier, Inserm U1183, University Hospital of Montpellier, Montpellier, France, ⁸APHP Henri Mondor Hospital, Creteil, France, ⁹Rheumatology Department, Bichat hospital, APHP, Paris, France, ¹⁰CHU Dijon, INSERM CAPS 1093, plateforme d’investigation technologique CIC1432, Dijon, France, ¹¹Lille University Hospital, Lille, France, ¹²Sorbonne University, INSERM, IPLES; Pitié-Salpêtrière Hospital, Paris, Ile-de-France, France, ¹³CHUGAI PHARMA FRANCE, Paris, France, ¹⁴Clinical Research Unit, Paris, ¹⁵AP-HP, UPEC, Créteil
Background/Purpose: To evaluate the efficacy of tocilizumab, an antibody against interleukin-6 receptor (IL-6R), in patients with hand osteoarthritis.Methods: This was a multicenter, 12-week, randomized, double-blind,…
Abstract Number: 1661 • ACR Convergence 2020
Systematic Review and Meta-Analysis of the Prevalence of Neuropathic-Like Pain and Pain Sensitisation in People with Knee and Hip Osteoarthritis
Luigi Zolio¹, Kai Ying Lim², Mabel Yan¹, Mahnuma Estee³, Sultana Monira Hussain⁴, Flavia Cicuttini⁴ and Anita Wluka⁵, ¹Alfred Health, Melbourne, Australia, ²Monash University, Kuala Lumpur, Malaysia, ³Monash University, Melbourne, Australia, ⁴Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia, ⁵Monash University, Melbourne, Victoria, Australia
Background/Purpose: Pain in osteoarthritis (OA) may be nociceptive or neuropathic-like in nature. In knee OA, pain severity is known to be poorly correlated with joint…
Abstract Number: 0140 • ACR Convergence 2020
Meaningful Within-Patient Change in WOMAC Domains in Patients with Moderate-To- Severe Osteoarthritis
Philip G Conaghan¹, Robert Dworkin², Thomas Schnitzer³, Francis Berenbaum⁴, Andrew Bushmakin⁵, Joseph Cappelleri⁵, Lars Viktrup⁶ and Lucy Abraham⁷, ¹Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and National Institute for Health Research Leeds Biomedical Research Centre, Leeds, United Kingdom, ²University of Rochester School of Medicine and Dentistry, Rochester, NY, ³Northwestern University Feinberg School of Medicine, Chicago, IL, ⁴Sorbonne Universite�, Paris, France, ⁵Pfizer Inc, Groton, CT, ⁶Eli Lilly and Company, Indianapolis, IN, ⁷Pfizer Inc, Tadworth, United Kingdom
Background/Purpose: The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) is a disease-specific measure of osteoarthritis (OA) symptoms (pain and stiffness) and functional impairment regularly…
Abstract Number: 0694 • ACR Convergence 2020
Relationships Among Adherence and Patient Outcomes in a Cognitive Behavioral Plus Physical Activity Intervention for Older Adults with Osteoarthritis and Hypertension
Xiaojun Shi¹, Elizabeth Schlenk² and Susan Sereika¹, ¹University of Pittsburgh School of Nursing, Pittsburgh, ²University of Pittsburgh School of Nursing, Pittsburgh, PA
Background/Purpose: Osteoarthritis of the knee (OAK) affects nearly 14 million older adults and more than half are diagnosed with hypertension (HTN). Cognitive behavior therapy (CBT)…
Abstract Number: 1109 • ACR Convergence 2020
Pain in Women with Knee and/or Hip Osteoarthritis Is Related to Systemic Inflammation and to Adipose Tissue Dysfunction and Distribution: A Cross-sectional Metabolic Biomarkers Cohort Study
Jeremie Sellam¹, Anne-Christine Rat², Soraya Fellahi³, Jean-Philippe Bastard⁴, Willy NGUEYON SIME⁵, Hang Korng EA⁶, Pascal Richette⁷, Jacqueline Capeau⁸, Francis Guillemin⁹ and Francis Berenbaum¹, ¹AP-HP, Hôpital Saint-Antoine, Service de Rhumatologie, Centre de Recherche Saint-Antoine, INSERM UMR_S 938,Sorbonne Université, Paris, 75012, France, Paris, France, ²Universite de Caen Normandie and Université de Lorraine, EA 4360, Caen, France, ³AP-HP INSERM, Paris, France, ⁴INSERM AP-HP UPEC, Paris, France, ⁵Universite de Lorraine, INSERM, CIC, Nancy, France, ⁶Universite de Paris, AP-HP, INSERM, paris, France, ⁷Department of Rheumatology, Lariboisière Hospital, Paris, France, ⁸INSERM Sorbonne Universite, Paris, France, ⁹Universite de Lorraine CIC INSERM, Nancy, France
Background/Purpose: Beyond the link between metabolic diseases and osteoarthritis (OA) risk, some studies have suggested an association between metabolic syndrome or visceral obesity and OA-related…
Abstract Number: 1489 • ACR Convergence 2020
Relation of Pain Mechanisms to Development of Knee Pain in Osteoarthritis: The Multicenter Osteoarthritis Study
Tuhina Neogi¹, Na Wang¹, Kosaku Aoyagi¹, Laura Frey Law², Cora Lewis³, Michael Nevitt⁴ and Lisa Carlesso⁵, ¹Boston University School of Medicine, Boston, MA, ²University of Iowa, Iowa City, IA, ³University of Alabama Birmingham, Birmingham, AL, ⁴University of California, San Francisco, San Francisco, CA, ⁵McMaster University, Hamilton, ON, Canada
Background/Purpose: Whether altered nociceptive signaling, such as pain sensitization and abnormal descending pain modulation, impact the risk of developing knee pain, more pain severity, and/or…
Abstract Number: 1662 • ACR Convergence 2020
Do Weight-bearing versus Non-weight-bearing Pain Reflect Different Pain Mechanisms in Knee Osteoarthritis?: The Multicenter Osteoarthritis Study
Jean Liew¹, John Farrar², Na Wang³, Lisa Carlesso⁴, Kosaku Aoyagi³, Laura Frey Law⁵, Cora Lewis⁶, Michael Nevitt⁷ and Tuhina Neogi³, ¹University of Washington, Seattle, WA, ²University of Pennsylvania, Philadelphia, PA, ³Boston University School of Medicine, Boston, MA, ⁴McMaster University, Hamilton, ON, Canada, ⁵University of Iowa, Iowa City, IA, ⁶University of Alabama Birmingham, Birmingham, AL, ⁷University of California, San Francisco, San Francisco, CA
Background/Purpose: Pain with weightbearing in knee OA is thought to be related to the activation of nociceptors; however, this is not considered the sole mechanism…
Abstract Number: 0157 • ACR Convergence 2020
Early Arthritis Global Assesment: What Differences Exist Between Patients and Physicians?
Cristina Valero¹, Noelia Garcia¹, Juan Pablo Baldivieso², Ana Ortiz³, Sebastian Rodriguez² and Isidoro González-Álvaro³, ¹Hospital Universitario de la Princesa, IIS-Princesa, UAM, Madrid, Madrid, Spain, ²Hospital de La Princesa, Madrid, Madrid, Spain, ³Hospital Universitario de la Princesa, IIS-Princesa, Madrid, Madrid, Spain
Background/Purpose: In recent years there is increasing evidence of the relevance of including the assessment of the different aspects of rheumatoid arthritis (RA) from the…
Abstract Number: 0709 • ACR Convergence 2020
Anatomical Distribution of Mrgprd-expressing Nonpeptidergic C-fibers in the Mouse Knee
Alia Obeidat¹, Rachel Miller¹ and Anne-Marie Malfait¹, ¹Rush University, CHICAGO, IL
Background/Purpose: The voltage-gated sodium channel, NaV1.8, marks the majority of C-fiber nociceptors. We have used NaV1.8 tdTomato reporter mice to describe the nociceptive innervation of…
Abstract Number: 1111 • ACR Convergence 2020
Intra-Articular Mineralization on Knee CT Increases Risk of Knee Pain: The Multicenter Osteoarthritis Study
Tuhina Neogi¹, John Lynch², Mohamed Jarraya³, David Felson¹, Na Wang¹, James Torner⁴, Cora Lewis⁵, Michael Nevitt⁶ and Ali Guermazi¹, ¹Boston University School of Medicine, Boston, MA, ²UCSF, San Francisco, CA, ³Boston University School of Medicine, Boston, ⁴University of Iowa, Iowa City, IA, ⁵University of Alabama Birmingham, Birmingham, AL, ⁶University of California, San Francisco, San Francisco, CA
Background/Purpose: Intra-articular (i.a.) calcium crystal deposition is common in knee osteoarthritis (OA). Low-grade inflammation related to crystals may contribute to knee pain, including pain fluctuation.…
Abstract Number: 1490 • ACR Convergence 2020
Pain Rating Variability and Response to Treatment in Osteoarthritis Clinical Trials
Camila Pinto¹, Joana Barroso² and Thomas Schnitzer³, ¹Department of Physiology, Northwestern University Feinberg School of Medicine, Chicago, IL, ²Department of Physiology, Northwestern University, Feinberg School of Medicine, Chicago, IL, ³Northwestern University Feinberg School of Medicine, Chicago, IL
Background/Purpose: Despite the known high inter- and intra-patient variability in analgesic responses in chronic pain, most interventional pain studies rely on single time point pain…

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