Abstracts tagged "pain"

Abstract Number: 1221 • ACR Convergence 2024
Efficacy of Immersive Virtual Reality-based Biofeedback on Chronic Pain and Daily Life Impact in Fibromyalgia: A Pilot Randomized Controlled Trial
Luca Chittaro¹, Simone Longhino², Marta Serafini¹, Sofia Cacioppo² and Luca Quartuccio³, ¹Human-Computer Interaction Lab, Department of Mathematics, Computer Science and Physics, University of Udine, Udine, Italy, ²Division of Rheumatology, Department of Medicine, University of Udine, UDine, Italy, ³Division of Rheumatology, Department of Medicine (DMED), University of Udine, Udine, Italy, Udine, Italy
Background/Purpose: Fibromyalgia (FM) affects 2% of the global population, causing chronic musculoskeletal pain, fatigue, sleep and mood disorders, significantly impacting quality of life. Although many…
Abstract Number: 1667 • ACR Convergence 2024
Correlates of Physical Activity (PA) in Persons Undergoing Total Knee Arthroplasty (TKA): Does Pain Matter?
Elena Losina¹, Jamie Collins¹, Clare Safran-Norton¹, Mike Paskewicz¹, Faith Selzer², Sonia Pavlesen³, Kelly Frier¹, Jon Dhani¹, Darya Lee¹, Ella Macdonald³, Alexa Streicher³, Linda Ehrlich-Jones⁴, Neil Segal⁵, Christine Pellegrini⁶, Elizabeth Wellsandt⁷, Rowland Chang⁸ and Jeffrey Katz¹, and KArAT Team, ¹Brigham and Women's Hospital, Boston, MA, ²Brigham and Women's Hospital, Amesbury, MA, ³University of Buffalo, Buffalo, NY, ⁴Shirley Ryan Ability Lab, Chicago, IL, ⁵University of Kansas, Kansas City, KS, ⁶University of South Carolina, Columbia, SC, ⁷University of Nebraska Medical Center, Omaha, NE, ⁸Northwestern University Division of Rheumatology, Chicago, IL
Background/Purpose: Low PA in persons with symptomatic knee osteoarthritis (OA) has often been attributed to pain. Evolving data suggest that TKA recipients do not increase…
Abstract Number: 2106 • ACR Convergence 2024
EP-104IAR (Long-Acting Intra-Articular Injection of Fluticasone Propionate) Shows Sustained Improvement in Pain for Subjects with Moderate Baseline Pain and BMI Less Than 30 in SPRINGBOARD, a Phase 2, Randomized, 24-Week Study of Osteoarthritis of the Knee
Amanda Malone¹, James Helliwell¹, Mark Kowalski¹, Helene Rovsing², Sidsel Lynggaard Boll³, Asger Reinstrup Bihlet⁴, Claire Prener Miller⁵, Alejandro Castillo Mondragón⁶, Yanqi Li⁶, Christine Dobek¹, Vik Peck¹, Andrew Dye¹, Mike Wilmink⁷, Lee Simon⁸ and Philip G Conaghan⁹, ¹Eupraxia Pharmaceuticals, Victoria, BC, Canada, ²NBCD A/S, Nordjylland, Denmark, ³NBCD A/S, Syddanmark, Denmark, ⁴NBCD A/S, Soeborg, Denmark, ⁵Novo Nordisk A/S, Bagsværd, Denmark, ⁶NBCD A/S, Soborg, Denmark, ⁷OrthoArizona, Phoenix, AZ, ⁸SDG LLC, West Newton, MA, ⁹Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom
Background/Purpose: Knee osteoarthritis (KOA) is a leading cause of disability associated with risk of cardiovascular disease and reduced self-management of diabetes and hypertension. Recommended treatment…
Abstract Number: 0592 • ACR Convergence 2024
Sustained Improvements with Bimekizumab in Patient-Reported Symptoms of Axial Spondyloarthritis: 2-Year Results from Two Phase 3 Studies
Helena Marzo-Ortega¹, Philip Mease², Maxime Dougados³, Maureen Dubreuil⁴, Marina Magrey⁵, Martin Rudwaleit⁶, Maria Antonietta D'Agostino⁷, Christine de la Loge⁸, Ute Massow⁹, Vanessa Taieb¹⁰, Diana Voiniciuc¹¹ and Atul Deodhar¹², ¹NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ²Swedish Medical Center/Providence St. Joseph Health; University of Washington School of Medicine, Seattle, WA, ³Rheumatology Department, Cochin Hospital and Clinical Epidemiology and Biostatistics, University of Paris, INSERM (U1153), Paris, France, ⁴Section of Rheumatology, Boston University School of Medicine, Boston, MA, ⁵Case Western Reserve University School of Medicine/University Hospitals, Richfield, OH, ⁶University of Bielefeld, Klinikum Bielefeld, Bielefeld, Germany, ⁷Division of Rheumatology, Fondazione Policlinico Universitario Agostino Gemelli IRCSS, Università Cattolica del Sacro Cuore, Rome, Italy, ⁸UCB Pharma, Brussels, Belgium, ⁹UCB Pharma, Monheim am Rhein, Germany, ¹⁰UCB Pharma, Colombes, France, ¹¹UCB Pharma, Slough, United Kingdom, ¹²Division of Arthritis and Rheumatic Diseases, Oregon Health & Science University, Portland, OR
Background/Purpose: In the phase 3 studies, BE MOBILE 1 and 2, bimekizumab (BKZ), a monoclonal IgG1 antibody that selectively inhibits interleukin (IL)-17F in addition to…
Abstract Number: 1185 • ACR Convergence 2024
Walking Is Associated with Less Knee Pain: A Cross-sectional Study from the Osteoarthritis Initiative
Sydney Tran¹, Jeffrey Driban², Timothy McAlindon³, Andrea Kriska⁴, Bonny Rockette-Wagner⁴, Charles Eaton⁵, Marc Hochberg⁶, Kent Kwoh⁷, Michael Nevitt⁸ and Grace Lo⁹, ¹Baylor College of Medicine, Houston, ²University of Massachusetts Chan Medical School, Worcester, MA, ³University of Massachusetts Chan Medical School, Worcester, ⁴University of Pittsburgh, Pittsburgh, PA, ⁵Warren Alpert Medical School of Brown University, Providence, RI, ⁶University of Maryland School of Medicine, Cambridge, MD, ⁷University of Arizona, Tucson, AZ, ⁸University of California, San Francisco, San Francisco, CA, ⁹Baylor College of Medicine / MEDVAMC, Houston, TX
Background/Purpose: Osteoarthritis (OA) is the most common form of arthritis, with the knee being the most common joint involved. Exercise is a leading non-pharmacological treatment…
Abstract Number: 1222 • ACR Convergence 2024
Large Language Model-driven Sentiment Analysis for Facilitating Fibromyalgia Diagnosis
Vincenzo Venerito and Florenzo Iannone, Rheumatology Unit- University of Bari "Aldo Moro", IT, Bari, Italy
Background/Purpose: Fibromyalgia (FM) is a complex disorder with widespread pain and emotional distress, posing diagnostic challenges. FM patients show altered cognitive and emotional processing, with…
Abstract Number: 1668 • ACR Convergence 2024
Association of Wearable-Sensor Derived Gait Measures with Widespread Pain over 2 Years: A Machine Learning Analysis in the Multicenter Osteoarthritis Study
Kathryn Bacon¹, David Felson², S. Reza Jafarzadeh³, Jeffrey Hausdorff⁴, Eran Gazi⁵, Neil Segal⁶, Cora Lewis⁷, Michael Nevitt⁸ and Deepak Kumar², ¹Boston University, Webster, NH, ²Boston University, Boston, MA, ³Boston University Chobanian & Avedisian School of Medicine, Boston, MA, ⁴Tel Aviv University, Tel Aviv, Israel, Tel Aviv, Israel, ⁵Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, ⁶University of Kansas, Kansas City, KS, ⁷University of Alabama at Birmingham, Birmingham, AL, ⁸University of California, San Francisco, San Francisco, CA
Background/Purpose: Gait patterns can put stress on the back and weight bearing joints and can even affect upper extremity joints. Walking involves muscle activation and…
Abstract Number: 2115 • ACR Convergence 2024
Clinical Impact of Acute Symptomatic Vertebral Fractures in the United States: An Observational Study
Neil Binkley¹, Michele McDermott², Eric Yeh², Joseph Lane³, Jolenta Cheung⁴, Mona Amet⁴ and Felicia Cosman⁵, ¹University of Wisconsin, Madison, ²Amgen Inc., Thousand Oaks, ³Hospital for Special Surgery, Weill Cornell Medical College, New York, NY, ⁴Adelphi Real World, Bollington, United Kingdom, ⁵Columbia University, College of Physicians and Surgeons, New York, NY
Background/Purpose: To characterize pain status (frequency, severity, persistency) and effect on activities of daily living (ADLs) in patients with symptomatic vertebral fractures (VF).Methods: This was…
Abstract Number: 0025 • ACR Convergence 2024
Vagus Nerve Stimulation: A Promising Approach to Alleviate Pain and Systemic Inflammation in Slow and Rapid Models of Osteoarthritis
Shivmurat Yadav¹, Timothy Griffin², Matlock Jeffries², Stavros Stavrakis³ and Mary Beth Humphrey⁴, ¹University of Oklahoma Health Sciences Center, Oklahoma City, OK, ²Oklahoma Medical Research Foundation, Oklahoma City, OK, ³University of Oklahoma, College of Mediicine, Oklahoma City, OK, ⁴University of Oklahoma College of Medicine, Oklahoma City, OK
Background/Purpose: Osteoarthritis (OA) causes joint pain, stiffness, swelling, and functional impairment. Pain signals reach the brain, influencing inflammatory and immune responses through the parasympathetic efferent…
Abstract Number: 0601 • ACR Convergence 2024
Early Improvement of Pain, Long-Term Disease Control, and Quality of Life Outcomes in Patients with Psoriatic Arthritis Treated with Upadacitinib
Peter C. Taylor¹, Lihi Eder², Yael Klionsky³, Fabian Proft⁴, Thomas Iyile⁵, Erin Mancl⁶, Priscila Magalhaes Reis Nakasato⁷, Xiaolan Ye⁸, Limei Zhou⁶ and Philip Mease⁹, ¹University of Oxford, Oxford, United Kingdom, ²University of Toronto, Women’s College Hospital and Department of Medicine, Toronto, ON, Canada, ³Division of Rheumatology, Department of Medicine, Wake Forest School of Medicine, Winston-Salem, NC, ⁴Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany, ⁵AbbVie Inc., hyattsville, MD, ⁶AbbVie Inc., North Chicago, IL, ⁷AbbVie Inc., Randolph, NJ, ⁸AbbVie Inc., Mettawa, IL, ⁹Swedish Medical Center/Providence St. Joseph Health; University of Washington School of Medicine, Seattle, WA

Background/Purpose: Severe musculoskeletal manifestations of PsA, particularly joint pain, can result in reduced physical function, decreased quality of life, and progressive and irreversible joint damage.1,2…
Abstract Number: 1191 • ACR Convergence 2024
Discordant Associations Among Chronological and Biological Age with Multi-joint Osteoarthritis and Symptom Burden: The Johnston County Health Study
Liubov Arbeeva¹, Yvonne Golightly², Cameron Kurz³, Matlock Jeffries⁴, Virginia Kraus⁵, Richard Loeser⁶, Duncan Lascelles⁷ and Amanda Nelson³, ¹University of North Carolina, Chapel Hill, Carrboro, NC, ²University of Nebraska Medical Center, Omaha, NE, ³University of North Carolina at Chapel Hill, Chapel Hill, NC, ⁴Oklahoma Medical Research Foundation, Oklahoma City, OK, ⁵Duke University, Durham, NC, ⁶University of North Carolina, Chapel Hill, NC, ⁷North Carolina State University, Raleigh, NC
Background/Purpose: Biological age (BA) may be superior to chronological age (CA) in predicting mortality and age-related conditions such as diabetes and cognitive/functional decline (PMID35715611), as…
Abstract Number: 1223 • ACR Convergence 2024
Community Based Study of Prevalence and Social Factors for Chronic Pain and Fibromyalgia in Women from Western India
Vidit Gupta¹, Diksha Mishra¹, Shikhar Singh¹, Vaishnavi Chowhan¹, Shraddha Thorat¹, Kavita Krishna² and Sandeep Kansurkar³, ¹Bharati Vidyapeeth (Deemed to be University) Medical College, Pune), Pune, Maharashtra, India, ²Bharati Vidyapeeth University Medical College and Hospital, Pune, Maharashtra, India, ³Bharati Vidyapeeth University Medical College, Pune, India
Background/Purpose: Fibromyalgia is a disorder of chronic widespread pain. There is huge burden of this entity in community but there is scarcity of quality studies…
Abstract Number: 1670 • ACR Convergence 2024
Predictors of 6-Minute Walk Test Performance in Adults with Arthritis
Kailyn Horn, Scott Jamieson, Katherine Devivo, Sara Wilcox, Yesil Kim, Chih-Hsiang Yang and Christine Pellegrini, University of South Carolina, Columbia, SC
Background/Purpose: The 6-Minute Walk Test (6MWT) is a measure commonly used by clinicians to assess functional capacity and rehabilitation progress. While predictors of 6MWT performance…
Abstract Number: 2149 • ACR Convergence 2024
Rheumatoid Arthritis: Patient’s Voice First! An Original Approach Based on Infodemiology Using Social Media Content – Results from the PRIMA Study
Jérémie Sellam¹, Luisa Attali², Sonia Trope³, Paméla Voillot⁴ and Cécile Gaujoux-Viala⁵, ¹Saint-Antoine Hospital - AP-HP, Paris, Ile-de-France, France, ²Centre de recherches en médecine, psychanalyse et société - Université Paris, Strasbourg, France, ³ANDAR, Paris, Ile-de-France, France, ⁴Kap code, Paris, France, ⁵CHU Nîmes, Nïmes, Languedoc-Roussillon, France

Background/Purpose: Social media and online forums are popular for understanding patients' feelings and concerns, which are hard to assess with traditional methods. Infodemiology collects and…
Abstract Number: 0028 • ACR Convergence 2024
Human Meniscus Histopathological and Transcriptomic Changes at Early and Advanced Stages of Knee Osteoarthritis
Takuya Sakamoto¹, Hannah Swahn¹, Merissa Olmer¹, Rachel Miller², Anne-Marie Malfait³ and Martin Lotz¹, ¹Scripps Research Institute, La Jolla, CA, ²Rush University Medical Center, Chicago, IL, ³Rush University Medical Center, Division of Rheumatology, Chicago, IL
Background/Purpose: The knee menisci are essential elements in joint biomechanics and meniscus damage is a driver of cartilage destruction and knee osteoarthritis. Meniscus damage and…

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