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Abstracts tagged "outcomes"

  • Abstract Number: 2985 • 2015 ACR/ARHP Annual Meeting

    Mycophenolate Mofetil (MMF) Use in Systemic Sclerosis (SSc) Patients with a Designation of Elevated Systolic Pulmonary Artery Pressure (sPAP): Forced Vital Capacity (FVC), Outcomes and Survival from the European Scleroderma Trials and Research (EUSTAR) Database

    Lesley Ann Saketkoo1, Dörte Huscher2, Christopher P. Denton3, Gabriela Riemekasten4, Virginia D. Steen5, Oliver Distler6 and EUSTAR member centres, 1Tulane University Lung Center, New Orleans Scleroderma and Sarcoidosis Patient Care and Research Center, New Orleans, LA, 2Charité-University Hospital and German Rheumatism Research Centre, Berlin, Germany, 3Rheumatology and Connective Tissue Diseases, University College London, London, United Kingdom, 4Clinic of Rheumatology, University of Luebeck, Lübeck, Germany, 5Rheumatology, Georgetown University Medical Center, Washington, DC, 6Research of Systemic Autoimmune Diseases, Division of Rheumatology, University Hospital Zurich, 8952 Schlieren, Switzerland

    Background/Purpose : SSc related PH carries a high mortality; with SSc-PH related to restrictive lung disease (RLD) having worse prognosis and more rapid time to…
  • Abstract Number: 1059 • 2014 ACR/ARHP Annual Meeting

    Patients with RA from Wealthier Countries Perform Better on Clinical Disease Activity Measures, but Tend to Show Worse Person Reported Outcomes

    Polina Putrik1, Sofia Ramiro2, Andras Keszei3, Ihsane Hmamouchi4, Maxime Dougados5, Monika Hifinger6, Laure Gossec7 and Annelies Boonen8, 1Department of Internal Medicine, Division of Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands, 2Rheumatology, Amsterdam Rheumatology Center, University of Amsterdam & Hospital Garcia de Orta, Almada, Portugal, Amsterdam, Netherlands, 3Medical Informatics, Uniklinik RWTH Aachen University, Aachen, Germany, 4Biostatistics, Epidemiology LBRCE, Mohamed V Souissi University, Rabat, Morocco, 5Cochin Hospital, Paris Descartes University, Paris, France, 6Rheumatology, MUMC, University Hospital Maastricht, Maastricht, Netherlands, 7Rheumatology, Pierre et Marie Curie University, Paris, France, 8Department of Internal Medicine, Division of Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands

    Background/Purpose Inequalities in health between low and high income countries are often reported, but it is not known whether clinical disease activity measures (“objective”) and…
  • Abstract Number: 811 • 2014 ACR/ARHP Annual Meeting

    Biologics in Takayasu Arteritis: Preliminary Data from the French Registry

    Arsene Mekinian1, Chloe Comarmond2, Mathieu Resche Regon3, Tristan Mirault4, Jean-Emmanuel Kahn5, Marc Lambert6, Jean Sibilia7, Antoine Neel8, Miguel Hié9, Emmanuel Messas10, Pascal Cohen11, Geraldine Muller12, Sabine Berthier13, Zahir Amoura14, Isabelle Marie15, Christian Lavigne16, Marie Anne Vandenhende17, Hervé Devilliers18, Sébastien Abad19, Loic Guillevin20, Mohamed Hamidou21, Bertrand Godeau22, Patrice Cacoub23, Olivier Fain24 and David Saadoun2, 1DHU2iB, Internal Medicine Saint Antoine Hospital, PARIS, France, 2DHU 2iB Internal Medicine Referal Center for Autoimmune diseases Pitie Hospital, Paris, France, 3biostatistics Saint Louis Hospital, paris, France, 4HEGP vascular department, paris, France, 5Internal Medicine, Foch Hospital, Suresnes, France, 6Faculté de Médecine Henri Warembourg, Université Lille Nord de France, Lille, France, 7Division of Rheumatology, University Hospital of Strasbourg, Strasbourg, France, 8INTERNAL MEDICINE, NANTES, France, 9Hôpital Pitié-Salpêtrière, AP-HP, UPMC Univ Paris 06 & French National Reference Center For Systemic Lupus and Antiphospholipid Syndrome, Paris, France, 10HEGP hospital Vascular and cardiology Department, paris, France, 11National Referral Center for Rare Systemic Autoimmune Diseases, Hôpital Cochin, AP–HP, Université Paris Descartes, Paris, Paris, France, 12INTERNAL MEDICINE, DIJON, France, 13DIJON HOSPITAL, DIJON, France, 14Internal medicine 2, French National Reference Center for Systemic Lupus and Antiphospholipid Syndrome, Pitié-Salpêtrière Hospital (AP-HP), Paris, France, 15CHU de Rouen, Rouen, France, 16CHU d'Angers, Angers, France, 17Internal Medicine, Bordeaux, France, 18Dijon University Hospital, Department of internal medicine and systemic diseases, Dijon, France, 19Hôpital Avicenne, Bobigny, France, 20Internal Medicine, Service de médecine interne, Centre de Références des Vascularites, Université Paris Descartes, APHP, Hôpital Cochin, 75005 Paris, France., Paris, France, 21CHU Hôtel Dieu, Nantes, Nantes, France, 22Service de médecine interne, Université Paris Est Créteil, AP-HP, Hôpital Mondor Créteil, France, Service de médecine interne, Université Paris Est Créteil, AP-HP, Hôpital Mondor Créteil, France, Creteil, France, 23Groupe Hospitalier Pitié Salpétrière, Service de Médecine Interne, DHU i2B, Paris, France, 24Hôpital Saint Antoine, DHU i2B, Service de Médecine Interne, paris, France

    Background/Purpose The aim of this registry is to determine: (1) the real-life use of various biological targeted treatments in Takayasu arteritis (TA) in France; (2)…
  • Abstract Number: 2903 • 2014 ACR/ARHP Annual Meeting

    Early Outcomes in Pediatric Antineutrophil Cytoplasmic Antibody (ANCA) Associated Vasculitis (AAV)

    Kimberly Morishita1, Susanne Benseler2, Rae S.M. Yeung3, Thomas Mason II4, Dawn Wahezi5, Kenneth N. Schikler6, Erica F. Lawson7, Susan Nielsen8, Sirirat Charuvanij9, Paul Dancey10, Susan Shenoi11, Linda Wagner-Weiner12, Angelyne Sarmiento1, David A. Cabral13 and For the PedVas Initiative1, 1BC Children's Hospital and University of British Columbia, Vancouver, BC, Canada, 2Pediatrics/Alberta Children's Hospital, Department of Pediatrics/University of Calgary, Calgary, AB, Canada, 3Rheumatology, The Hospital for Sick Children and University of Toronto, Toronto, ON, Canada, 4Division of Rheumatology - Department of Medicine, Mayo Clinic, Rochester, MN, 5Pediatric Rheumatology, Children's Hospital at Montefiore, Bronx, NY, 6Department of Pediatrics, Univ of Louisville Schl of Med, Louisville, KY, 7Pediatrics, University of California, San Francisco, San Francisco, CA, 8Pediatric rheumatology, Rigshospitalet, Copenhagen, Denmark, 9Pediatrics, Siriraj Hospital, Bangkok, Thailand, 10Pediatrics, Janeway Children's Hospital, St. John's, NL, Canada, 11Pediatric Rheumatology, Seattle Childrens Hospital, seattle, WA, 12Pediatric Rheumatology, University of Chicago Hospital, Chicago, IL, 13Pediatrics, BC Children's Hospital and University of British Columbia, Vancouver, BC, Canada

    Background/Purpose:  Childhood AAV is rare and outcome studies are limited.  The PedVas Study is an international initiative collecting clinical data (to A Registry of Childhood…
  • Abstract Number: 813 • 2014 ACR/ARHP Annual Meeting

    Long-Term Outcomes of Takayasu’s Arteritis Patients with Renal Artery Involvement

    Corisande Baldwin1, Aladdin Mohammad2 and David Jayne3, 1Rheumatology, University of British Columbia, Vancouver, BC, Canada, 2Dept. of Rheumatology, Lund University Hospital, Lund University, Lund, Lund, Sweden, 3Vasculitis and Lupus Clinic, Addenbrookes Hospital University of Cambridge, Cambridge, United Kingdom

    Background/Purpose: Takayasu's Arteritis (TAK) is a chronic inflammatory large vessel vasculitis characterized by granulomatous inflammation of the aorta and its branches. TAK incidence is 2.6/million…
  • Abstract Number: 2911 • 2014 ACR/ARHP Annual Meeting

    Clinical Outcomes of Early RA after 7 Years – Does T2T Approach Overcome Delay of Therapy?

    Tuulikki Sokka1, Hannu Kautiainen2, Tuomas Rannio3, Juha Asikainen1 and Pekka Hannonen1, 1Jyvaskyla Central Hospital, Jyväskylä, Finland, 2Medcare Oy, Äänekoski, Finland, 3Kuopio University Hospital, Kuopio, Finland

     Background/Purpose: Early vs. delayed referral/start of therapy within 3-4 months has been shown beneficial for outcomes in rheumatoid arthritis (RA) (Lard et al. AM J…
  • Abstract Number: 685 • 2014 ACR/ARHP Annual Meeting

    Successful Withdrawal and Discontinuation of Immunosuppressants in Lupus Patients: Outcomes and Predictors

    Zahi Touma1, Murray B. Urowitz2, Dominique Ibanez1 and Dafna D. Gladman2, 1Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 2University of Toronto, Toronto Western Hospital, Toronto, ON, Canada

    Background/Purpose:   Physicians and patients (Pts) are hesitant to withdraw immunosuppressant (IS) in Pts in clinical remission as the consequences of this approach are unknown.…
  • Abstract Number: 2812 • 2014 ACR/ARHP Annual Meeting

    Is Rheumatoid Arthritis the Same Disease in Women and Men?- Joint Damage in Patients with EARLY Rheumatoid Arthritis at 10 YEARS after Diagnosis

    Juha Asikainen1, Kalevi Kaarela2, Heidi Mäkinen3, Hannu Kautiainen4, Pekka Hannonen5, Tuomas Rannio6 and Tuulikki Sokka7, 1Jyvaskyla Central Hospital, Jyväskylä, Finland, 2Jyväskylä Central Hospital, Jyväskylä, Finland, 3Tampere University Hospital, Tampere, Finland, 4Medcare Oy, Äänekoski, Finland, 5Jyväskylä Central Hospital, Jyvaskyla, Finland, 6Kuopio University Hospital, Kuopio, Finland, 7Jyvaskyla Central Hospital, Jyvaskyla, Finland

    Background/Purpose: Rheumatoid arthritis (RA) is suggested to be a more severe disease in women than in men as disease activity appears higher in women, and…
  • Abstract Number: 573 • 2014 ACR/ARHP Annual Meeting

    Three-Year Course and Prediction of Physical Functioning in Ankylosing Spondylitis Patients Treated with TNF-Inhibitors

    Salima F.E. van Weely1, Eva L. Kneepkens1, Mike T. Nurmohamed1, Joost Dekker1,2 and Irene E. van der Horst-Bruinsma3, 1Reade, centre for Rehabilitation and Rheumatology, Amsterdam, Netherlands, 2Rehabilitation Medicine, Psychiatry and EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, Netherlands, 3Rheumatology, VU University Medical Centre, Amsterdam, Netherlands

    Background/Purpose: Currently, only limited information is available on the long-term course of limitations in physical functioning and spinal mobility in Ankylosing Spondylitis (AS) patients receiving…
  • Abstract Number: 2786 • 2014 ACR/ARHP Annual Meeting

    Aortitis: Outcomes from a Cohort of 196 Patients

    Alison Clifford1, Amr Arafat2, Jahanzaib Idrees2, Eric Roselli2, Carmela D. Tan3, E. Rene Rodriguez3, Lars Svensson2, Eugene Blackstone2 and Gary S. Hoffman1, 1Center for Vasculitis Care and Research, Cleveland Clinic Foundation, Cleveland, OH, 2Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic Foundation, Cleveland, OH, 3Department of Anatomic Pathology, Cleveland Clinic Foundation, Cleveland, OH

    Background/Purpose: Idiopathic aortitis is a rare diagnosis that may occur in the context of a primary systemic vasculitis, as part of a systemic autoimmune disease,…
  • Abstract Number: 546 • 2014 ACR/ARHP Annual Meeting

    Psoriatic Arthritis Mutilans: Characteristics and Radiographic Progression

    Deepak R. Jadon1, Gavin Shaddick2, William Tillett1, Graham Robinson3, Charlotte Cavill1, Nicola Waldron1, Eleanor Korendowych1 and Neil J McHugh4, 1Rheumatology, Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom, 2Department of Mathematics, University of Bath, Bath, United Kingdom, 3Royal United Hospital, Bath, United Kingdom, 4Department of Pharmacy and Pharmacology, University of Bath, Bath, United Kingdom

    Background/Purpose: Psoriatic arthritis mutilans (PAM) is a rare extreme subtype of psoriatic arthritis (PsA). Our objectives were to: (1) compare clinical characteristics of PsA patients…
  • Abstract Number: 2626 • 2014 ACR/ARHP Annual Meeting

    Relationship of Socio-Demographic and Disease Factors with Loss-to-Follow-up and Appointment Noncompliance in Indigent Patients with Systemic Lupus Erythematosus

    Angela Pham1, Gaobin Bao2, S. Sam Lim3 and Cristina Drenkard4, 1Rheumatology, Emory University, Atlanta, GA, 2Medicine, Emory University, Atlanta, GA, 3Emory University School of Medicine, Division of Rheumatology, Atlanta, GA, 4Medicine, Div Rheumatology, Emory University, Atlanta, GA

    Background/Purpose .  The relationship of medical noncompliance with poor health outcomes has been described in chronic diseases, including systemic lupus erythematosus (SLE).  These outcomes are…
  • Abstract Number: 382 • 2014 ACR/ARHP Annual Meeting

    What Is More Predictive of Achieving Remission at 12 Months: The Percentage of Baseline Improvement or the Actual Disease State Achieved at 6 Months?

    Edward C. Keystone1, Carter Thorne2, Michael Starr3, Jude Rodrigues4, Philip Baer5, Regan Arendse6, J. Antonio Avina-Zubieta7, Denis Choquette8, Emmanouil Rampakakis9, John S. Sampalis9, May Shawi10, Francois Nantel10, Allen J Lehman11 and Susan Otawa11, 1Medicine, University of Toronto, Toronto, ON, Canada, 2Southlake Regional Health Centre, Newmarket, ON, Canada, 3Rheumatology, McGill University Health Centre, Montreal, QC, Canada, 4Clinical Research and Arthritis Centre, Windsor, ON, Canada, 5Private Practice, Scarborough, ON, Canada, 6University of Saskatchewan, Saskatoon, SK, Canada, 7Rheumatology, Arthritis Research Centre of Canada, Richmond, BC, Canada, 8Rheumatology, Institut de rhumatologie de Montréal (IRM), Montréal, QC, Canada, 9JSS Medical Research, Montreal, QC, Canada, 10Janssen Inc., Toronto, ON, Canada, 11Medical Affairs, Janssen Inc., Toronto, ON, Canada

    Background/Purpose: The aim of rheumatoid arthritis (RA) treatment is to optimize symptom control and, when possible, achieve sustained remission. Therefore, identification of clinical signs predicting…
  • Abstract Number: 2403 • 2014 ACR/ARHP Annual Meeting

    From Early Arthritis Clinic to Remission Clinic: Short-Term Outcome and Ultrasonographic-Synovitis Dynamics in Rheumatoid Arthritis Patients in DMARD-Induced SDAI-Remission during Drug-Free Follow-up

    Antonio Manzo1, Francesca Benaglio1, Garifallia Sakellariou1, Martina Scarabelli1, Elisa Binda1, Barbara Vitolo1, Serena Bugatti1, Roberto Caporali2 and Carlomaurizio Montecucco1, 1Rheumatology and Translational Immunology Research Laboratories (LaRIT), Division of Rheumatology, IRCCS Policlinico S.Matteo Foundation/University of Pavia, Pavia, Italy, 2Division of Rheumatology, Rheumatology and Translational Immunology Research Laboratories (LaRIT), Division of Rheumatology, IRCCS Policlinico S.Matteo Foundation/University of Pavia, Pavia, Italy

    Background/Purpose The introduction of DAS-driven intensive treatment strategies in early rheumatoid arthritis (RA) has considerably improved outcome and patients’ quality of life. Previous studies have…
  • Abstract Number: 375 • 2014 ACR/ARHP Annual Meeting

    Evaluation of RAPID3 with Minimal Joint Count and ACR/EULAR Provisional Remission Definitions As Predictors of Future Good Radiographic + Functional Outcome in a Double-Blind, Phase 3, Randomized Controlled Trial of Tocilizumab

    Martin J. Bergman1, Jeffrey Yourish2, Jinglan Pei2, Jenny Devenport2, William Reiss2 and Edward Keystone3, 1Taylor Hospital, Ridley Park, PA, 2Genentech, South San Francisco, CA, 3University of Toronto and Mount Sinai Hospital, Toronto, ON, Canada

    Background/Purpose: Based on treat-to-target guidelines, the goal of treatment should be remission. Definitions for remission recommended by the ACR/EULAR task force include joint counts and…
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