ACR Meeting Abstracts

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Abstracts tagged "Outcome measures"

  • Abstract Number: 2332 • ACR Convergence 2024

    PsAID12 Thresholds Defining Disease Impact Severity in Psoriatic Arthritis Developed in an Observational Setting Showed Higher Sensitivity but Lower Specificity Than Those Developed in a Randomized Controlled Trial Setting

    Clementina López Medina1, Ana-Maria Orbai2, Ennio Lubrano3, Laura Coates4, Uta Kiltz5, Ying Ying Leung6, PENELOPE PALOMINOS7, Juan Cañete8, Rossana Scrivo9, Andra Balanescu10, Emmanuelle Dernis11, Sandra Meisalu12, Adeline Ruyssen-Witrand13, MArtin Soubrier14, Sibel Aydin15, Lihi Eder16, Umut Kalyoncu17, Josef Smolen18, Maarten de Wit19 and Laure Gossec20, 1Reina Sofia University Hospital, Cordoba, Spain, 2Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, 3Vincenzo Tiberio Department of Medicine and Health Sciences, University of Molise, Campobasso, Italy, 4University of Oxford, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Oxford, United Kingdom, 5Rheumazentrum Ruhrgebiet Herne, Ruhr-University, D-44649 Herne, Germany, 6Singapore General Hospital, Singapore, Singapore, 7Hospital de Clinicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil, 8Hospital Clinic an IDIBAPS, Barcelona, Spain, 9Sapienza Università di Roma, Rome, Italy, Roma, Italy, 10UNIVERSITY OF MEDICINE AND PHARMACY CAROL DAVILA, Bucharest, Romania, 11CH LE MANS, LE MANS, Pays de la Loire, France, 12Physician, Tallinn, Estonia, 13Toulouse University Hospital, Toulouse, France, 14Gabriel-Montpied Hospital, Clermont-ferrand, France, 15University of Ottawa - Ottawa, Ottawa, ON, Canada, 16University of Toronto, Women’s College Hospital and Department of Medicine, Toronto, ON, Canada, 17Hacettepe University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Ankara, Turkey, 18Medical University of Vienna, Vienna, Austria, 19Stichting Tools, Patient Research Partner, Amsterdam, Netherlands, 20Sorbonne Université, Paris, France

    Background/Purpose: The Psoriatic Arthritis (PsA) Impact of Disease questionnaire (PsAID12) score (range 0-10) allows for the assessment of patient-important symptoms and life impact in PsA.…
  • Abstract Number: 0137 • ACR Convergence 2024

    The Problem of Pain in Rheumatology: Sociodemographic and Disease-related Correlates of Agreement Between Structured Data Elements and Clinical Notes in Chronic Pain Documentation Practices in EHR

    Tahmina Begum1, Bhagyavalli Veeranki1, Ogenna Chike1 and Titilola Falasinnu2, 1Stanford School of Medicine, Stanford, 2Stanford School of Medicine, Palo Alto, CA

    Background/Purpose: To create greater precision in case definitions for chronic pain in EHRs, we recently identified 15 different case definitions for chronic pain using structured…
  • Abstract Number: 0378 • ACR Convergence 2024

    Disparate Disease Activity Outcomes Associated with Demographic Variables in Patients with Juvenile Idiopathic Arthritis in the Pediatric Rheumatology Care and Outcomes Improvement Network Registry

    Julia Harris1, Catherine Bingham2, Sheetal Vora3, Cagri Yildirim-Toruner4, Kerry Ferraro5, Erik Friedrichsen6, Michelle Batthish7, Jon Burnham8, Danielle Fair9, Suhas Ganguli10, Mileka Gilbert11, Beth Gottlieb12, Tzielan Lee13, Daniel Lovell14, Melissa Mannion15, Edward Oberle16, Nancy Pan17, Linda Ray18, Michael Shishov19, Mary Toth20 and Esi Morgan21, 1Children's Mercy Kansas City, Overland Park, KS, 2Penn State Children’s Hospital, Hershey, 3Atrium Health Levine Children's Hospital, Charlotte, NC, 4Baylor College of Medicine/ Texas Children's Hospital, Houston, TX, 5JIA parent and CHOP volunteer, Lower Gwynedd, PA, 6Seattle Children's Hospital, Seattle, 7McMaster Children's Hospital, Hamilton, ON, Canada, 8Children's Hospital of Philadelphia, Philadelphia, PA, 9Medical College of Wisconsin/Children's Wisconsin, Wauwatosa, WI, 10Hackensack University Medical Center, Hackensack, 11Medical University of South Carolina, Charleston, SC, 12Cohen Children's Medical Center, Lake Success, NY, 13Stanford University School of Medicine, Palo Alto, CA, 14Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 15University of Alabama at Birmingham, Birmingham, AL, 16Nationwide Children's Hospital, Columbus, OH, 17Hospital for Special Surgery, Weill Cornell Medicine, New York, NY, 18University of Mississippi Medical Center, Jackson, MS, 19Phoenix Children's Hospital, Phoenix, AZ, 20Nemours Foundation, Orlando, FL, 21Seattle Children's Hospital, Seattle, WA

    Background/Purpose: The Pediatric Rheumatology Care and Outcomes Improvement Network (PR-COIN) is a North American learning health network focused on improving outcomes in patients with juvenile…
  • Abstract Number: 0599 • ACR Convergence 2024

    Sex- related Differences in Efficacy of Biologics in Axial Spondyloarthritis: A Systematic Review and Meta-analysis

    Haseeb Chaudhary1, Omer Pamuk2, Sarah Abi Doumeth3, Ansaam Daoud4, Muhammad Shamim5 and Marina Magrey6, 1Case Western Reserve University, Westlake, OH, 2University Hospitals Cleveland Medical Center/ Case Western Reserve University, Cleveland, OH, 3Case Western Reserve University/University Hospitals Cleveland Medical Center, Cleveland Heights, OH, 4Case Western Reserve University/University Hospitals, Akron, OH, 5University Hospitals/ Case Western Reserve University, Cuyahoga Falls, OH, 6Case Western Reserve University School of Medicine/University Hospitals, Richfield, OH

    Background/Purpose: There is limited information about sex-related differences in efficacy of biologics in axial spondyloarthritis (axSpA).  We hypothesized that females with axSpA are less likely…
  • Abstract Number: 0722 • ACR Convergence 2024

    Factors Associated with Relapses and Performance of the French Vasculitis Study Group Relapse Score in a Cohort of Mexican Patients with ANCA-Associated Vasculitis

    Andrea Hinojosa-Azaola1, Marlon Sandino-Bermúdez2, Ana Sarahí Mulia-Soto3, Juan M. Mejía-Vilet4 and Eduardo Martin Nares5, 1Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, Mexico City, Mexico, 2Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, Mexico City, Distrito Federal, Mexico, 3Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, Ciudad de México, Mexico, 4Department of Nephrology and Mineral Metabolism, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, Mexico City, Mexico, 5Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico

    Background/Purpose: Anti-neutrophil cytoplasm antibody-associated vasculitis (AAV) encompass a group of systemic inflammatory diseases with multi-organ involvement. Relapses occur in 14-44% of patients within 18-36 months…
  • Abstract Number: 1045 • ACR Convergence 2024

    Impact of Stable Rheumatologic Therapy on Outcomes of Depression in Members with Rheumatoid Arthritis, Psoriatic Arthritis, and Systemic Lupus Erythematosus

    Jean Park1, Cliff Rutter2, Elisea Avalos-Reyes3, Mary Anderson4, Will Cavers5, Dorothea Verbrugge6 and Kjel Johnson7, 1CVS Health, Hartford, CT, 2CVS Health, Fair Oaks Ranch, TX, 3CVS Health, Highland Village, TX, 4CVS Health, Irving, TX, 5CVS Health, Palm Beach Gardens, 6CVS Health, Salt Lake City, 7CVS Health, Tampa

    Background/Purpose: Rheumatic diseases, such as rheumatoid arthritis (RA), psoriatic arthritis (PA), and systemic lupus erythematosus (SLE) can significantly impact quality of life. This burden extends…
  • Abstract Number: 1394 • ACR Convergence 2024

    Nationwide Retrospective Cohort Study on Clinical Outcomes in Rheumatoid Arthritis Patients Treated with JAK Inhibitors

    Yurilu Gonzalez Moret1, Diego Lema2 and Fabian Rodriguez Quinonez3, 1Jefferson Einstein Hospital, Philadelphia, PA, 2Universidad Central de Venezuela, University of Wisconsin, Philadelphia, PA, 3Einstein Medical Center Philadelphia, Philadelphia, PA

    Background/Purpose: Janus kinase inhibitors (JAKi) are a class of disease activity-modifying drugs (DMARDs) that have quickly established a role in managing rheumatoid arthritis. Inhibition of…
  • Abstract Number: 1597 • ACR Convergence 2024

    Baseline Glucocorticoid-Related Toxicity in Newly-Diagnosed and Relapsing ANCA-Associated Vasculitis

    Naomi Patel1, Sarah Bray2, Darcy Trimpe3, David Jayne4, Peter Merkel5 and John Stone6, 1Massachusetts General Hospital, Boston, MA, 2Amgen Ltd, Cambridge, United Kingdom, 3Amgen Inc., Thousand Oaks, CA, 4University of Cambridge, Cambridge, United Kingdom, 5University of Pennsylvania, Philadelphia, PA, 6Massachusetts General Hospital , Harvard Medical School, Concord, MA

    Background/Purpose: The ADVOCATE trial evaluated avacopan (a C5a receptor antagonist) as a replacement for a standard prednisone taper in the treatment of granulomatosis with polyangiitis…
  • Abstract Number: 2143 • ACR Convergence 2024

    Analysis of Effectiveness and Safety of Romosozumab in Patients with Very High Risk of Fracture in a Spanish Population

    Marina soledad Moreno Garcia1, Roxana González Mazario2, yedra uson Rodriguez3, Erardo meriño Ibarra4, Emilio Giner5, Juan Carlos Cobeta García6, Marilia Arce Benavente7, maria Dolores Fábregas canales8, Julia Ullier Bellmunt3, Giuliano Boselli3, pilar martinez Valles7, Jorge Juan Fragío Gil9, carlos Vazquez Galeano7 and Ana Turrion Nieves10, 1hospital Miguel Servet . Zaragoza, Zaragoza, Aragon, Spain, 2Hospital General de Valencia, Valencia, Comunidad Valenciana, Spain, 3hospital miguel servet, zaragoza, Aragon, Spain, 4Hospital San Jorge Huesca, zaragoza, 5Hospital Royo Villanova, Teruel, Spain, 6Hospital Ernest Lluch, zaragoza, 7hospital miguel servet, Zaragoza, 8Hospital de Barbastro, Huesca, Spain, 9Hospital General Universitario, Valencia, Comunidad Valenciana, Spain, 10Rheumatology Department, Hospital Universitario Virgen de la Vega, Salamanca, Spain

    Background/Purpose: Excluding clinical trials, there is limited evidence on the effect of 12 months of romosozumab treatment on increasing bone mineral density (BMD) in real-world…
  • Abstract Number: 2366 • ACR Convergence 2024

    Improvement in Pain-Associated Biomarkers with Deucravacitinib, a First-in-Class, Oral, Selective, Allosteric Tyrosine Kinase 2 Inhibitor, in Patients with PsA in a Double-Blind Phase 2 Study (IM011-084)

    Philip Mease1, Christopher Ritchlin2, Lu Gao3, Peter Schafer4, Miroslawa Nowak3, Ian M. Catlett3 and Jinqi Liu3, 1Swedish Medical Center/Providence St. Joseph Health; University of Washington School of Medicine, Seattle, WA, 2Department of Medicine, Allergy, Immunology, and Rheumatology Division, University of Rochester Medical School, Canandaigua, NY, 3Bristol Myers Squibb, Princeton, NJ, 4Bristol Myers Squibb, BELLE MEAD, NJ

    Background/Purpose: Pain is a core domain of PsA, and reduction of pain is a primary treatment concern for patients with PsA. Pain has been reported…
  • Abstract Number: 0149 • ACR Convergence 2024

    Beliefs on Self-Management in Rheumatoid Arthritis Compared to Other Chronic Diseases Using the Nationally Representative Medical Expenditure Panel Survey

    Samuel Good1, Bryant England2 and Elizabeth Volkmann3, 1University of California, Los Angeles, Los Angeles, CA, 2University of Nebraska Medical Center, Omaha, NE, 3University of California, Department of Medicine, Los Angeles, CA, USA, Los Angeles

    Background/Purpose: Studies that evaluate experiences of living with rheumatoid arthritis (RA) have found that patients identify self-empowerment and a sense of control as important factors…
  • Abstract Number: 0385 • ACR Convergence 2024

    Cross-cultural Validation of the “Effects of Youngsters-Eyesight on Quality of Life (EYE-Q)”: A Measure of Vision-related Quality of Life and Function in Childhood Uveitis

    sheila Angeles-Han1, Jordi Anton2, Amra Adrovic3, Patricia Costa Reis4, Joke De Boer5, Séverine Guillaume-Czitrom6, Theresa Hennard7, Marija Jelusic8, Ozgur Kasapcopur9, Ilaria Maccora10, Hana Malcova11, Joseph McDonald12, Najima Mwase13, Gabriele Simonini14, Waheba Slamang15, Derrik du Toit16, Hendrike van Vollenhoven16 and Ivan Foeldvari17, 1Cincinnati Children's Hospital, Cincinnati, OH, 2Hospital Sant Joan de Déu. Universitat de Barcelona, Esplugues de Llobregat (Barcelona), Spain, 3Deparment of Pediatric Rheumatology, Istanbul University-Cerrahpasa, Istanbul, Turkey, 4Hospital de Santa Maria, Lisbon, Portugal, 5Department of ophthalmology, University Medical Center Utrecht, Utrecht, Netherlands, 6University Hospital of Bicetre, Kremlin-Bicêtre, France, 7Cincinnati Children's Hospital and Medical Center, Cincinnati, OH, 8University of Zagreb School of Medicine, University Hospital Centre Zagreb, Zagreb, Zagreb, Croatia, 9Istanbul University-Cerrahpasa, Cerrahpasa Medical School, istanbul, Turkey, 10?PhD student, in the Area of Drugs and Innovative Treatments, NeuroFARBA Department, University of Florence. Meyer Children's Hospital, Florence Italy, Firenze, Florence, Italy, 11FN Motol, Praha, Czech Republic, 12University of Chicago, Chicago, IL, 13Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 14Meyer Children Hospital IRCCS; NEUROFARBA Department, University of Florence, Florence, Italy, 15University of Cape Town, Department of Child and Adolescent Health, Cape Town, South Africa, 16Red Cross Children’s Hospital, Cape Town, South Africa, 17Hamburg Centre for Pediatric and Adolescence Rheumatology, Hamburg, Germany

    Background/Purpose: Childhood uveitis leads to sight-threatening complications in 50% of affected children and significantly impacts a child’s quality of life and function. The Multinational Interdisciplinary…
  • Abstract Number: 0615 • ACR Convergence 2024

    Socioeconomic Determinants of Lupus Hospitalization Outcomes: A Review of Current Knowledge and Analysis of the 2016-2019 NRD Database

    Akhila Arya P V1, Madhumitha Rondla2, Jai Juganya Tirupur Ponnusamy3 and Dileep C Unnikrishnan4, 1Bridgeport Hospital, Stratford, CT, 2Texas tech university health sciences center, El paso, El Paso, TX, 3Metrowest Medical Center, Framingham, 4Bridgeport Hospital, Bridgeport, CT

    Background/Purpose: Hospitalizations due to systemic lupus erythematosus (SLE) often stem from lupus flares and infections. Socioeconomic factors influencing outcomes in SLE hospitalizations have been studied…
  • Abstract Number: 0733 • ACR Convergence 2024

    Inpatient Outcomes in ANCA-Associated Vasculitis: An In-Depth Cross-Sectional Analysis Using NIS Data (2016-2020)

    Sai Shanmukha Sreeram Pannala1, fares Saliba2, Medha Rajamanuri3 and Veena Katikineni4, 1Staten Island University Hospital, Northwell Health, staten island, new york city, NY, 2Staten Island University Hospital, Staten Island, NY, 3Southern Illinois University School of Medicine, Springfield, IL, 4Providence, Victorville, CA

    Background/Purpose: Antineutrophilic cytoplasmic antibody (ANCA)-associated vasculitides (AAV) are a heterogeneous group of rare autoimmune conditions characterized by inflammation of blood vessels, leading to various clinical…
  • Abstract Number: 1047 • ACR Convergence 2024

    Impact of Treatment Switching on Adherence in Members with Rheumatoid Arthritis, Psoriatic Arthritis, or Systemic Lupus Erythematosus

    Jean Park1, Cliff Rutter2, Elisea Avalos-Reyes3, Mary Anderson4, Will Cavers5, Dorothea Verbrugge6 and Kjel Johnson7, 1CVS Health, Hartford, CT, 2CVS Health, Fair Oaks Ranch, TX, 3CVS Health, Highland Village, TX, 4CVS Health, Irving, TX, 5CVS Health, Palm Beach Gardens, 6CVS Health, Salt Lake City, 7CVS Health, Tampa

    Background/Purpose: Switching treatment from conventional to biologic disease-modifying antirheumatic drugs (DMARDs) is a common practice for managing autoimmune diseases such as rheumatoid arthritis (RA), psoriatic…
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