ACR Meeting Abstracts

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Abstracts tagged "Outcome measures"

  • Abstract Number: 2466 • ACR Convergence 2024

    Ranked Composite Important Difference (RCID) Scores in Patients with Diffuse Cutaneous Systemic Sclerosis and Interstitial Lung Disease

    Francesco Del Galdo1, Lesley-Anne Bissell2, Rozeta Simonovska3 and Margarida Alves4, 1University of Leeds, Leeds, United Kingdom, 2Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, 3mainanalytics GmbH, Sulzbach (Taunus), Germany, Sulzbach (Taunus), Germany, 4Boehringer Ingelheim International GmbH, Ingelheim am Rhein, Germany, Ingelheim, Germany

    Background/Purpose: The ACR Composite Response Index in diffuse cutaneous Systemic Sclerosis (CRISS) was developed to measure the probability of improvement in response to treatment in…
  • Abstract Number: 0266 • ACR Convergence 2024

    Analysis of Gout Remission Definitions in a Randomised Controlled Trial of Colchicine Prophylaxis for People with Gout Initiating Allopurinol

    Dansoa Tabi-Amponsah1, Lisa Stamp2, Anne Horne3, Jill Drake4, Sarah Stewart5, Gregory Gamble3, Keith Petrie1 and Nicola Dalbeth3, 1The University of Auckland, Auckland, New Zealand, 2University of Otago, Christchurch, Christchurch, New Zealand, 3University of Auckland, Auckland, New Zealand, 4University of Otago, Christchurch, New Zealand, 5Auckland University of Technology, Auckland, New Zealand

    Background/Purpose: To investigate the effect of colchicine prophylaxis on gout remission when commencing urate lowering therapy (ULT), and illness perceptions of people in remission, using…
  • Abstract Number: 0541 • ACR Convergence 2024

    Measurement Properties of Disease Activity Instruments in Peripheral Spondyloarthritis. an Analysis in the CRESPA Trial

    Clementina López Medina1, Anna Molto2, Dafne Capelusnik3, Philippe Carron4, Casper Webers5, Filip Van den Bosch6, Annelies Boonen7 and Sofia Ramiro8, 1Reina Sofia University Hospital, Cordoba, Spain, 2Groupe Hospitalier Cochin, AP-HP, Paris, France, 3Tel Aviv Sourasky Medical Center, Ramat Gan, Israel, 4UZ Gent, Gent, Belgium, 5Department of Internal Medicine, Division of Rheumatology, Maastricht University Medical Centre, Maastricht, 6Ghent University Hospital, Ghent, Belgium, 7Department of Internal Medicine, Division of Rheumatology, Maastricht University Medical Center; Care and Public Health Research Institute (Caphri), Maastricht University, Maastricht, Netherlands, 8Leiden University Medical Center, Bunde, Netherlands

    Background/Purpose: Understanding the best-performing disease activity measure and response criterion in peripheral spondyloarthritis (pSpA) is crucial for the development of future meaningful clinical studies. The…
  • Abstract Number: 0656 • ACR Convergence 2024

    Lupus Myocarditis: Clinical Characteristics, Cardiac Magnetic Resonance Imaging Findings and Outcomes

    María del Carmen Zamora-Medina1, Erik Cimé-Aké2, Emilio G. Lazarini2, Wallace Rafael A. Muñoz-Castañeda3 and Hilda Fragoso-Loyo2, 1Instituto Nacional de Perinatología "Isidro Espinoza de los Reyes". Rheumatology Department, Mexico City, Distrito Federal, Mexico, 2Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán. Immunology and Rheumatology Department, Mexico City, Mexico, 3Hospital Medica Sur. Rheumatology Department, Mexico City, Distrito Federal, Mexico

    Background/Purpose: Limited information about lupus myocarditis (LM) comes from small case series. The aim of our study is to describe and compare clinical characteristics, cardiac…
  • Abstract Number: 0847 • ACR Convergence 2024

    Sex and Race-Specific Distributions in Medial Fixed Joint Space Width in Healthy Knees from Three Longitudinal Cohorts

    Kent Kwoh1, Rongrong Tang2, Erin Ashbeck3, Edward Bedrick4, Yvonne Golightly5, Amanda Nelson6, Tuhina Neogi7, Yong Ge8, Zong-Ming Li2, Jean Liew7, Xiaoxiao Sun9, Justin Crawmer10 and Jeffery Duryea11, 1University of Arizona, Tucson, AZ, 2University of Arizona Arthritis Center, University of Arizona College of Medicine - Tucson, Tucson, AZ, 3University of Arizona Mel and Enid Zuckerman College of Public Health, Tucson, AZ, 4Department of Epidemiology andBiostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, 5University of Nebraska Medical Center, Omaha, NE, 6University of North Carolina at Chapel Hill, Chapel Hill, NC, 7Boston University Chobanian & Avedisian School of Medicine, Boston, MA, 8Department of Information Sciences, Eller College of Manangement, University of Arizona, Tucson, AZ, 9Department of Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ, 10BWH, Boston, MA, 11Brigham and Women’s Hospital, Harvard Medical School, Boston, MA

    Background/Purpose: Quantitative radiographic joint space width (JSW)  is often used as ameasure of structural outcomes in randomized controlled trials of knee OA (KOA). How JSW…
  • Abstract Number: 1148 • ACR Convergence 2024

    Simplified Cutaneous Dermatomyositis Disease Area and Severity Index Activity Scores for Cutaneous Dermatomyositis

    Nantakarn Pongtarakulpanit1, Tanya Chandra1, shiri keret2, Eugenia Gkiaouraki3, Vladimir Liarski1, Dana Ascherman3, Siamak Mogahadam1, Chester Oddis1 and Rohit Aggarwal4, 1Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 2Rheumatology unit, Bnai-Zion medical center and the faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel., Atlit, Israel, 3Division of Rheumatology and Clinical Immunology, University of Pittsburgh Medical Center, Pittsburgh, PA, 4Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, USA, Pittsburgh, PA

    Background/Purpose: The Cutaneous Dermatomyositis Disease Area and Severity Index (CDASI) is a clinician-scored instrument that measures activity and damage in the skin of Dermatomyositis (DM)…
  • Abstract Number: 1502 • ACR Convergence 2024

    The Systemic Lupus International Collaborating Clinics (SLICC) Frailty Index (SLICC-FI) Predicts Hospitalizations. Data from the Almenara Lupus Cohort

    Manuel Ugarte-Gil1, RV, Gamboa-Cardenas2, Victor Pimentel-Quiroz3, Cristina Reategui4, Claudia Elera Fitzcarrald5, Cesar Pastor-Asurza6, Zoila Rodriguez-Bellido6, Risto Perich-Campos6 and Graciela Alarcon7, 1Universidad Cientifica del Sur, Lima, Lima, Peru, 2Universidad Científica del Sur, Lima, Lima, Peru, 3Universidad Científica del Sur/Hospital Nacional Guillermo Almenara Irigoyen, Magdalena del Mar, Peru, 4Servicio de Reumatología. Hospital Nacional Guillermo Almenara Irigoyen, EsSalud/Grupo Peruano de Estudio de Enfermedades Autoinmunes Sistémicas, Universidad Científica del Sur, Lima, Lima, Peru, 5Hospital Nacional Guillermo Almenara Irigoyen/Universidad San Ignacio de Loyola, Lima, Peru, 6Hospital Nacional Guillermo Almenara Irigoyen, Lima, Lima, Peru, 7The University of Alabama at Birmingham, Oakland, CA

    Background/Purpose: Frailty, measured with the SLICC-FI, has been reported as a predictor of damage in several cohorts. The aim of this study is to evaluate…
  • Abstract Number: 1934 • ACR Convergence 2024

    Knee Symptom Phenotyping Incorporating Pain and Function: A Multiple-Trajectory Modeling-Based Study Using Data from the Osteoarthritis Initiative (OAI)

    Yong Ge1, Thang Doung2, Shen Liu3, Xiaoxiao Sun4, Tuhina Neogi5, Amanda Nelson6, Jeffery Duryea7 and Kent Kwoh8, 1Department of Information Sciences, Eller College of Manangement, University of Arizona, Tucson, AZ, 2Department of Computer Science, University of Arizona College of Science, Tucson, AZ, 3Department of Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ, 4Department of Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ, 5Boston University Chobanian & Avedisian School of Medicine, Boston, MA, 6University of North Carolina at Chapel Hill, Chapel Hill, NC, 7Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, 8University of Arizona, Tucson, AZ

    Background/Purpose: Knee pain is the most common presenting symptom of knee OA, and functional limitations are a common sequelae. Understanding the various patterns of pain…
  • Abstract Number: 2245 • ACR Convergence 2024

    Clinical Efficacy and Molecular Cardiovascular Changes of Baricitinib in Biologic-naïve Patients with Rheumatoid Arthritis. Direct Comparative Analysis with TNF Inhibitors and Conventional DMARDs

    Chary Lopez-Pedrera1, Laura Muñoz-Barrera2, Rafaela Ortega-Castro3, Sagrario Corrales2, Jerusalén Calvo4, Concepción Aranda-Valera5, María Lourdes Ladehesa-Pineda1, Pilar Font2, Ismael Sánchez Pareja2, Elena Moreno-Caño5, María Carmen Ábalos-Aguilera6, Christian Merlo-Ruiz6, Mª Angeles Aguirre-Zamorano7, Tomás Cerdó2, Nuria Barbarroja2, Carlos Perez-Sanchez2 and Alejandro Escudero-Contreras2, 1IMIBIC/Reina Sofia Hospital/University of Cordoba, Cordoba, Andalucia, Spain, 2IMIBIC/Reina Sofia Hospital/University of Cordoba, Cordoba, Spain, 3Hospital Reina Sofía, Cordoba, Andalucia, Spain, 4IMIBIC/Reina Sofia Hospital/University of Cordoba, Córdoba, Spain, 5IMIBIC/Reina Sofia Hospital/University of Cordoba, Córdoba, Andalucia, Spain, 6IMIBIC/Reina Sofia Hospital/University of Cordoba, CÓRDOBA, Spain, 7IMIBIC/Reina Sofia Hospital/University of Cordoba, CÓRDOBA, Andalucia, Spain

    Background/Purpose: The main objective of this study was to conduct extensive clinical and molecular analyses to accurately characterize the specific effects of Baricitinib (4 mg/day)…
  • Abstract Number: 2497 • ACR Convergence 2024

    Clinical Characteristics and Outcomes of Hydralazine-induced ANCA-associated Vasculitis. a Single Center Retrospective Cohort Analysis from the US

    Muhammad Shamim1, Mazen Allouni2, Haseeb Chaudhary3, Ansaam Daoud4, Loai Dweik5, Hashim Syed6 and Omer Pamuk7, 1University Hospitals/ Case Western Reserve University, Cuyahoga Falls, OH, 2Case Western Reserve, University Hospitals, Cleveland Medical Center, Cleveland, OH, 3Case Western Reserve University, Westlake, OH, 4Case Western Reserve University/University Hospitals, Akron, OH, 5Cleveland Clinic Akron General Internal Medicine, Akron, OH, 6Case Western/ UH, Cleveland, 7University Hospitals Cleveland Medical Center/ Case Western Reserve University, Cleveland, OH

    Background/Purpose: Hydralazine-induced ANCA-associated vasculitis (HIAAV) is a rare clinical problem.  There is paucity of data regarding clinical features, treatment, and prognosis of hydralazine-induced AAV in…
  • Abstract Number: 0269 • ACR Convergence 2024

    Delphi Survey to Establish Consensus on the OMERACT Core Domain Set for Long-Term Studies of Calcium Pyrophosphate Deposition Disease

    Yiling Zhang1, Sara Tedeschi2, Abhishek Abhishek3, Owen Hensey4, David Grossberg5, Ken Cai6, Beverley Shea7, Jasvinder Singh8, Robin Christensen9, Teodora Serban10, Edoardo Cipolletta11, Konstantinos Parperis12, César Díaz13, Geraldine McCarthy14, Fabio Becce15, Tamer A Gheita16, Silvia Sirotti17, Sara Nysom Christiansen18, Luis Coronel Tarancon19, Lisa Stamp20, Yousra H Abdel-Fattah21, Tristan Pascart22, Georgios Filippou17, Lih En Hong23, John FitzGerald24 and Nicola Dalbeth1, 1University of Auckland, Auckland, New Zealand, 2Brigham and Women's Hospital, Boston, MA, 3University of Nottingham, Nottingham, United Kingdom, 4OMERACT patient research partner, Dublin, Ireland, 5OMERACT patient research partner, Maryland, 6Westmead Hospital, Sydney, New South Wales, Australia, 7Ottawa Hospital Research Institute, Ottawa, ON, Canada, 8Baylor College of Medicine, Birmingham, AL, 9Musculoskeletal Statistics Unit, The Parker Institute, Copenhagen, Denmark, 10Ospedale La Colletta, Bucharest, Romania, 11Polytechnic University of Marche, Ancona, Italy, 12University of Cyprus Medical School, Nicosia, Cyprus, 13Hospital de la Santa Creu i Sant Pau, Barcelona, Spain, 14Mater Misericordiae University Hospital, Dublin, Ireland, 15Lausanne University Hospital (CHUV), Lausanne, Switzerland, 16Rheumatology Department, Faculty of Medicine, Cairo University, Cairo, Egypt, 17IRCCS Galeazzi - Sant'Ambrogio Hospital, Milan, Italy, 18Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, Denmark., Glostrup, Denmark, 19Image and Technics Unit, Department of Rheumatology. Hospital Universitari Vall d’Hebron, Barcelona, Spain, 20University of Otago, Christchurch, Christchurch, New Zealand, 21Alexandria University, Alexandria, Egypt, 22Lille Catholic University, Lille, France, 23Royal Adelaide Hospital, Unley Park, South Australia, Australia, 24UCLA, Los Angeles, CA

    Background/Purpose: To agree on important domains for the Outcome Measures in Rheumatology (OMERACT) core domain set for long-term studies of calcium pyrophosphate deposition (CPPD) disease.Methods:…
  • Abstract Number: 0542 • ACR Convergence 2024

    Impact of Peripheral Arthritis on Disease Activity Outcomes in Patients with Axial Spondyloarthritis, Peripheral Spondyloarthritis and Psoriatic Arthritis. Data from the ASAS-PerSpA Study

    Clementina López Medina1, Sofia Ramiro2, Dafne Capelusnik3 and Anna Molto4, 1Reina Sofia University Hospital, Cordoba, Spain, 2Leiden University Medical Center, Bunde, Netherlands, 3Tel Aviv Sourasky Medical Center, Ramat Gan, Israel, 4Groupe Hospitalier Cochin, AP-HP, Paris, France

    Background/Purpose: Patients with spondyloarthritis (SpA) can present with several phenotypes (i.e., axial SpA (axSpA), peripheral SpA (pSpA) and Psoriatic Arthritis (PsA)) and peripheral arthritis can…
  • Abstract Number: 0659 • ACR Convergence 2024

    Obinutuzumab Benefits Patients with Active Lupus Nephritis Irrespective of Baseline Proteinuria Severity: A Post Hoc Analysis of a Phase II Trial

    Richard Furie1, Jorge A. Ross Terres2, Elsa Martins3, Imran Hassan4, Thomas Schindler3, Jay Garg5, William F. Pendergraft III6, Ana Malvar7 and Brad Rovin8, 1Northwell Health, Manhasset, NY, 2Genentech, Inc,, San Francisco, 3F. Hoffmann-La Roche Ltd, Basel, Switzerland, 4Hoffmann-La Roche Ltd, Mississauga, Canada, 5Genentech, Inc., South San Francisco, CA, 6Genentech, Inc., Chapel Hill, NC, 7Organización Médica de Investigación, Buenos Aires, Argentina, 8The Ohio State University, Columbus, OH

    Background/Purpose: Lupus nephritis (LN) is the most common severe organ-threatening manifestation of systemic lupus erythematosus (SLE). The randomized, placebo-controlled, Phase II NOBILITY trial (NCT02550652) demonstrated…
  • Abstract Number: 0857 • ACR Convergence 2024

    Exploring Clinical Outcomes of Patients with Cardiac Sarcoidosis on TNF Inhibitors: A Nationwide Retrospective Cohort Study

    Yurilu Gonzalez Moret1, Diego Lema2 and Fabian Rodriguez Quinonez3, 1Jefferson Einstein Hospital, Philadelphia, PA, 2Universidad Central de Venezuela, University of Wisconsin, Philadelphia, PA, 3Einstein Medical Center Philadelphia, Philadelphia, PA

    Background/Purpose: Immunosuppressive therapy, including Tumor necrosis factor inhibitors (TNFi), is commonly used in the treatment of various inflammatory conditions, including extracardiac sarcoidosis. However, the use…
  • Abstract Number: 1180 • ACR Convergence 2024

    Relationship Between Changes in Physical Activity and Early Onset Knee Osteoarthritis in Individuals After ACL Reconstruction

    David Werner1, Yvonne Golightly1, Michael Rosenthal1, Balasrinivasa Sajja1, Christopher Wichman1, Melissa Manzer2, Matthew Tao1 and Elizabeth Wellsandt1, 1University of Nebraska Medical Center, Omaha, NE, 2Private Practice, Omaha

    Background/Purpose: Low physical activity levels are associated with osteoarthritis (OA) development and progression in individuals at risk for OA development. Including both structural and symptomatic…
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