Abstracts tagged "Outcome measures"

Abstract Number: 2100 • 2012 ACR/ARHP Annual Meeting
Relative, Reliability-Adjusted Diagnostic Test Accuracy of Erosion Detection Between Magnetic Resonance Imaging and Radiography in Rheumatoid Arthritis
Ruben Tavares¹, Naveen Parasu², Karen Finlay², Erik Jurriaans², Hao Wu¹, Karen A. Beattie³, Maggie Larche⁴, Lawrence E. Hart⁵, William G. Bensen⁶, Raja S. Bobba⁴, Alfred A. Cividino³, Colin E. Webber⁷, Jean-Eric Tarride⁸ and Jonathan D. Adachi⁹, ¹McMaster University, Hamilton, ON, Canada, ²Radiology, Hamilton Health Sciences, Hamilton, ON, Canada, ³Medicine, McMaster University, Hamilton, ON, Canada, ⁴Rheumatology, McMaster University, Hamilton, ON, Canada, ⁵Medicine (Rheumatology), St. Joseph's Health Care, Hamilton, ON, Canada, ⁶Department of Medicine, Division of Rheumatology, St. Joseph's Hospital and McMaster University, Hamilton, ON, Canada, ⁷Department of Nuclear Medicine, Hamilton Health Sciences, Hamilton, ON, Canada, ⁸Clinical Epidemiology and Biostatistics (CE&B) and Economics, Programs for Assessment of Technology in Health (PATH) Research Institute, Hamilton, ON, Canada, ⁹St Joseph's Healthcare Hamilton, Hamilton, ON, Canada
Background/Purpose: In rheumatoid arthritis (RA), erosion detection on radiography (X-ray) compared to magnetic resonance imaging (MRI) is characterized by low sensitivity and high specificity. This…
Abstract Number: 710 • 2012 ACR/ARHP Annual Meeting
Optical Density Measure of the Papillary Dermis Discriminates As Abnormal Clinically Uninvolved Skin in Systemic Sclerosis and Correlates with Severity of Skin Thickness
Giuseppina Abignano¹, Sibel Z. Aydin², Concepcion Castillo-Gallego³, Daniel Woods⁴, Adam Meekings⁵, Dennis McGonagle⁶, Paul Emery⁷ and Francesco Del Galdo⁸, ¹Chapel Allerton Hospital Leeds Insitute of Molecular medicine, Division of Rheumatic and Musculoskeletal Disease, University of Leeds, Leeds Institute of Molecular Medicine and LMBRU, Leeds, United Kingdom, ²Unit of Rheumatology, Medeniyet University, Goztepe Training and Research Hospital, Istanbul, Turkey, ³Rheumatology, Hospital La Paz - IdiPaz, Madrid, Spain, ⁴Michelson Diagnostics Ltd, Kent, United Kingdom, ⁵Michelson Diagnostics Ltd, Kent, United Kingdom, Kent, United Kingdom, ⁶Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ⁷Division of Rheumatic and Musculoskeletal Disease, University of Leeds, Leeds Institute of Molecular Medicine and LMBRU, Leeds, United Kingdom, ⁸Musculoskeletal Diseases, University of Leeds, Leeds Institute of Molecular Medicine and LMBRU, Leeds, United Kingdom
Background/Purpose: Skin involvement in systemic sclerosis (SSc) is often primary outcome in clinical trials and its severity inversely correlates with prognosis. Nevertheless, an objective quantitative…
Abstract Number: 2064 • 2012 ACR/ARHP Annual Meeting
Regular Measure of Disease Activity During the Routine Care of Rheumatoid Arthritis Patients Involves Some Extra Work but Positive Results
Lissiane K. N. Guedes¹, Ana Cristina Medeiros Ribeiro², Karina Rossi Bonfiglioli³, Diogo Domiciano¹, Carolina Reither Vizioli¹, Gilmara Franco da Cunha¹, Andressa Silva Abreu¹, Filipi M. Mello¹, Ana Luiza de Aguiar Foelkel⁴, Celio R. Gonçalves¹ and Ieda Laurindo¹, ¹Rheumatology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ²Reumatologia, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, ³Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ⁴Rheumatology, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil
Background/Purpose: According to treat to target recommendations the use of validated composite measures of disease activity, which include joint assessments, is needed in routine clinical…
Abstract Number: 631 • 2012 ACR/ARHP Annual Meeting
Peripheral Neuropathy Due to Systemic Lupus Erythematosus (SLE) Itself: Incidence, Disease Risk Factors and Outcome
Simone Fargetti¹, Samuel K. Shinjo², Sandra G. Pasoto¹, Ana L. Calich¹, Eloisa Bonfa³ and Eduardo F. Borba¹, ¹Rheumatology Division, University of Sao Paulo, Sao Paulo, Brazil, ²Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, Sao Paulo, Brazil, ³Rheumatology Division, University of São Paulo, Sao Paulo, Brazil
Background/Purpose: Peripheral neuropathy (PN) solely attributable to SLE itself is difficult to define since most of these patients are exposed to several other conditions that…
Abstract Number: 2068 • 2012 ACR/ARHP Annual Meeting
Is There a Difference in Rheumatology Patient Reported Outcomes When Measured At Home Versus the Clinic Setting?
C.J. Inman¹, Frederick Wolfe² and Kaleb Michaud³, ¹Pediatric Administration, University of Utah, Salt Lake City, UT, ²National Data Bank for Rheumatic Diseases, Wichita, KS, ³Rheumatology, National Data Bank for Rheumatic Diseases & University of Nebraska Medical Center, Omaha, NE
Background/Purpose: Registries have become a common tool for collecting patient-centered outcome measures. Clinical effectiveness research may be improved if data from multiple registries could be…
Abstract Number: 563 • 2012 ACR/ARHP Annual Meeting
In Ankylosing Spondylitis, a Decrease in MRI Spinal Inflammation Predicts Improvement in Spinal Mobility Independently of Patient Reported Symptomatic Improvement
Pedro Machado¹, Robert Landewé², Jürgen Braun³, Xenofon Baraliakos⁴, Kay-Geert A. Hermann⁵, Benjamin Hsu⁶, Daniel Baker⁷ and Désirée van der Heijde¹, ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Clinical Immunology & Rheumatology, Academic Medical Center, University of Amsterdam and Atrium Medical Center, Heerlen, Netherlands, ³PsAID taskforce, EULAR, Zurich, Switzerland, ⁴Rheumatology, Rheumazentrum Ruhrgebiet, Herne, Germany, ⁵Radiology, Charité Universitätsmedizin Berlin, Campus Mitte, Berlin, Germany, ⁶Janssen Research & Development, LLC., Spring House, PA, ⁷Research and Development, Centocor Inc., Malvern/Philadelphia, PA
Background/Purpose: It has been previously shown that spinal mobility in ankylosing spondylitis (AS) is associated with the level of inflammation of the spine. However an…
Abstract Number: 2029 • 2012 ACR/ARHP Annual Meeting
Reliability of Scoring a Disease Damage Measure for Juvenile Localized Scleroderma
Kathryn S. Torok¹, Suzanne C. Li², Christina Kelsey³, Mara L Becker⁴, Fatma Dedeoglu⁵, Robert C. Fuhlbrigge⁶, Gloria Higgins⁷, Sandy D. Hong⁸, Maria F. Ibarra⁹, Ronald Laxer¹⁰, Thomas G. Mason II¹¹, Marilynn G. Punaro¹², Elena Pope¹³, C. Egla Rabinovich¹⁴ and Katie G. Stewart¹², ¹Pediatric Rheumatology, Scleroderma Center of Pittsburgh, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, ²Pediatrics, Joseph M Sanzari Children's Hospital, Hackensack University Medical Center, Hackensack, NJ, ³Pediatric Rheumatology, Univ of Pittsburgh Med Ctr, Pittsburgh, PA, ⁴Clinical Pharmacology and Rheumatology, Children's Mercy Hospital, Kansas City, MO, ⁵Division of Immunology, Boston Children's Hospital, Boston, MA, ⁶Pediatric Rheumatology, Childrens Hospital, Boston, MA, ⁷Pediatric Rheumatology NATIONWIDE CHILDRENS HOSPITAL, PRCSG-Cincinnati Children's Hospital Medical Center, Columbus, OH, ⁸Pediatrics-Rheumatology, U of Iowa Children's Hosp, Iowa City, IA, ⁹Pediatric Rheumatolgy, Children's Mercy Hospital, Kansas City, MO, ¹⁰Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, ¹¹Rheumatology, Mayo Clinic Rochester, Rochester, MN, ¹²Pediatric Rheumatology, Texas Scottish Rite Hospital, Dallas, TX, ¹³Dermatology, The Hospital for Sick Children, Toronto, ON, Canada, ¹⁴Pediatric Rheumatology, Duke University Medical Center, Durham, NC
Background/Purpose: . In order to more accurately capture disease activity and damage in juvenile Localized Scleroderma (jLS) and to develop an accepted outcome measure for…
Abstract Number: 397 • 2012 ACR/ARHP Annual Meeting
Assessment of Global Disease Activity in Rheumatoid Arthritis Patients Monitored in the Measurement of Efficacy of Treatment in the Era of Rheumatology Database: The patient’s Versus the rheumatologist’s Opinion
E. Gvozdenovic¹, R. Koevoets¹, R. Wolterbeek², Désirée van der Heijde³, T.W.J. Huizinga¹, C.F. Allaart¹ and Robert B. M. Landewé⁴, ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Biostatistics, Leiden University Medical Center, Leiden, Netherlands, ³Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁴Academic Medical Center/University of Amsterdam & Atrium Medical Center, Amsterdam, Netherlands
Background/Purpose: Disagreement on disease activity between rheumatoid arthritis (RA) patients and rheumatologists may influence treatment decisions and compliance. The aim is to compare the physician's…
Abstract Number: 2037 • 2012 ACR/ARHP Annual Meeting
Poor Quality of Gout Care Is Strongly Associated with Higher Gout-Related Health Care Utilization
Jasvinder A. Singh¹ and Joshua Richman², ¹Department of Medicine, University of Alabama, Tuscaloosa, AL, ²Biostatistics, UAB School of Medicine, Birmingham, AL
Background/Purpose: Proponents of improving quality of gout care have suggested various gout quality indicators, but no study to date has shown the link between…
Abstract Number: 403 • 2012 ACR/ARHP Annual Meeting
The Impact of Reaching Low Disease Activity in the First Year On Future Disability and Damage in Patients with Early Rheumatoid Arthritis
Pooneh Akhavan¹, George A. Tomlinson², Paul R. Fortin³ and Claire Bombardier¹, ¹Rheumatology, University of Toronto, Toronto, ON, Canada, ²Dept of Medicine/Rheumatology, Toronto General Hospital, Toronto, ON, Canada, ³Medicine, Centre de Recherche du Chu de Québec et Université Laval, Quebec City, QC, Canada
Background/Purpose: Remission has been proposed as the goal of treatment in patients with early rheumatoid arthritis (RA) by current clinical practice guidelines. Remission is ideal…
Abstract Number: 1723 • 2012 ACR/ARHP Annual Meeting
The Development of the Rheumatoid Arthritis Patient Priorities in Pharmacological Intervention Outcome Measures
Tessa Sanderson¹, John R. Kirwan², Marianne Morris¹, Jon Pollock³, Robert Noddings², Anne Watts² and Sarah Hewlett⁴, ¹University of the West of England, Bristol, United Kingdom, ²Academic Rheumatology Unit, Bristol Royal Infirmary, Bristol, United Kingdom, ³Faculty of Health and Life Sciences, University of the West of England, Bristol, United Kingdom, ⁴Academic Rheumatology, University of the West of England, Bristol, United Kingdom
Background/Purpose: Previous research developed a set of 8 priority treatment outcomes generated by patients to complement the professionally developed ACR core set for RA. These…
Abstract Number: 359 • 2012 ACR/ARHP Annual Meeting
Improved Radiological Outcome of Rheumatoid Arthritis: Early Treatment with methotrexate might be a key Prognostic Factor
Christoph Fiehn¹, Elisabeth Belke-Voss¹, Dietmar Krause², Siegfried Wassenberg³ and Rolf Rau⁴, ¹ACURA Centre for Rheumatic Diseases, Baden-Baden, Germany, ²Dept. for Medical Informatics, Biometry and Epidemiology, Ruhr University, Bochum, Germany, ³Rheumaklinik, Evangelisches Fachkrankenhaus Ratingen, Rheumazentrum, Ratingen, Germany, ⁴Düsseldorf, Germany
Background/Purpose: To compare the rate of radiological progression in patients with rheumatoid arthritis (RA) diagnosed in the 1980s with those of the late 1990s until…
Abstract Number: 1578 • 2012 ACR/ARHP Annual Meeting
How Disease Activity Trajectories Affect the Willingness to Change Treatment
Paul Falzer¹ and Liana Fraenkel², ¹Medicine, VA Connecticut Healthcare System, New Haven, CT, ²Medicine, Section of Rheumatology, Yale University School of Medicine, Veterans Affairs Connecticut Healthcare System, New Haven, CT
Background/Purpose: Disease activity (DA) can change markedly over a short period, for a variety of reasons. The changes influence clinical practice and affect the willingness…
Abstract Number: 298 • 2012 ACR/ARHP Annual Meeting
Childhood-Onset Predicts Increased Disease Damage and Steroid Toxicity in a Cohort of Adults with Systemic Lupus Erythematosus
Erica F. Lawson¹, Laura Trupin², Jinoos Yazdany³, Aimee Hersh⁴, Emily von Scheven⁵ and Edward H. Yelin⁶, ¹Pediatrics, University of California, San Francisco, San Francisco, CA, ²Medicine, University of California San Francisco, San Francisco, CA, ³Medicine, University of California, San Francisco, San Francisco, CA, ⁴Pediatrics, University of Utah, Salt Lake City, UT, ⁵Pediatric Rheumatology, University of California San Francisco, San Francisco, CA, ⁶Arthritis Research Group, University of California, San Francisco, San Francisco, CA
Background/Purpose: While previous work has shown that adults with childhood-onset systemic lupus erythematosus (cSLE) have increased risk of mortality, renal disease and myocardial infarction as…
Abstract Number: 1526 • 2012 ACR/ARHP Annual Meeting
Patient Reported Outcomes in ANCA-Associated Vasculitis. A Prospective Comparison Between Birmingham Vasculitis Activity Score and Routine Assessment of Patient Index Data 3
Osama ElSallabi¹, Joel A. Block¹ and Antoine Sreih², ¹Section of Rheumatology, Rush University Medical Center, Chicago, IL, ²Medicine/Rheumatology, Rush University Medical Center, Chicago, IL
Background/Purpose: ANCA-associated vasculitis (AAV) is a rare group of diseases comprising Granulomatosis with polyangiitis (Wegener’s; GPA), Microscopic Polyangiitis (MPA), and Churg-Strauss Syndrome (CSS). These diseases…

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