ACR Meeting Abstracts

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Abstracts tagged "Outcome measures"

  • Abstract Number: 1502 • ACR Convergence 2024

    The Systemic Lupus International Collaborating Clinics (SLICC) Frailty Index (SLICC-FI) Predicts Hospitalizations. Data from the Almenara Lupus Cohort

    Manuel Ugarte-Gil1, RV, Gamboa-Cardenas2, Victor Pimentel-Quiroz3, Cristina Reategui4, Claudia Elera Fitzcarrald5, Cesar Pastor-Asurza6, Zoila Rodriguez-Bellido6, Risto Perich-Campos6 and Graciela Alarcon7, 1Universidad Cientifica del Sur, Lima, Lima, Peru, 2Universidad Científica del Sur, Lima, Lima, Peru, 3Universidad Científica del Sur/Hospital Nacional Guillermo Almenara Irigoyen, Magdalena del Mar, Peru, 4Servicio de Reumatología. Hospital Nacional Guillermo Almenara Irigoyen, EsSalud/Grupo Peruano de Estudio de Enfermedades Autoinmunes Sistémicas, Universidad Científica del Sur, Lima, Lima, Peru, 5Hospital Nacional Guillermo Almenara Irigoyen/Universidad San Ignacio de Loyola, Lima, Peru, 6Hospital Nacional Guillermo Almenara Irigoyen, Lima, Lima, Peru, 7The University of Alabama at Birmingham, Oakland, CA

    Background/Purpose: Frailty, measured with the SLICC-FI, has been reported as a predictor of damage in several cohorts. The aim of this study is to evaluate…
  • Abstract Number: 1934 • ACR Convergence 2024

    Knee Symptom Phenotyping Incorporating Pain and Function: A Multiple-Trajectory Modeling-Based Study Using Data from the Osteoarthritis Initiative (OAI)

    Yong Ge1, Thang Doung2, Shen Liu3, Xiaoxiao Sun4, Tuhina Neogi5, Amanda Nelson6, Jeffery Duryea7 and Kent Kwoh8, 1Department of Information Sciences, Eller College of Manangement, University of Arizona, Tucson, AZ, 2Department of Computer Science, University of Arizona College of Science, Tucson, AZ, 3Department of Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ, 4Department of Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ, 5Boston University Chobanian & Avedisian School of Medicine, Boston, MA, 6University of North Carolina at Chapel Hill, Chapel Hill, NC, 7Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, 8University of Arizona, Tucson, AZ

    Background/Purpose: Knee pain is the most common presenting symptom of knee OA, and functional limitations are a common sequelae. Understanding the various patterns of pain…
  • Abstract Number: 2245 • ACR Convergence 2024

    Clinical Efficacy and Molecular Cardiovascular Changes of Baricitinib in Biologic-naïve Patients with Rheumatoid Arthritis. Direct Comparative Analysis with TNF Inhibitors and Conventional DMARDs

    Chary Lopez-Pedrera1, Laura Muñoz-Barrera2, Rafaela Ortega-Castro3, Sagrario Corrales2, Jerusalén Calvo4, Concepción Aranda-Valera5, María Lourdes Ladehesa-Pineda1, Pilar Font2, Ismael Sánchez Pareja2, Elena Moreno-Caño5, María Carmen Ábalos-Aguilera6, Christian Merlo-Ruiz6, Mª Angeles Aguirre-Zamorano7, Tomás Cerdó2, Nuria Barbarroja2, Carlos Perez-Sanchez2 and Alejandro Escudero-Contreras2, 1IMIBIC/Reina Sofia Hospital/University of Cordoba, Cordoba, Andalucia, Spain, 2IMIBIC/Reina Sofia Hospital/University of Cordoba, Cordoba, Spain, 3Hospital Reina Sofía, Cordoba, Andalucia, Spain, 4IMIBIC/Reina Sofia Hospital/University of Cordoba, Córdoba, Spain, 5IMIBIC/Reina Sofia Hospital/University of Cordoba, Córdoba, Andalucia, Spain, 6IMIBIC/Reina Sofia Hospital/University of Cordoba, CÓRDOBA, Spain, 7IMIBIC/Reina Sofia Hospital/University of Cordoba, CÓRDOBA, Andalucia, Spain

    Background/Purpose: The main objective of this study was to conduct extensive clinical and molecular analyses to accurately characterize the specific effects of Baricitinib (4 mg/day)…
  • Abstract Number: 2497 • ACR Convergence 2024

    Clinical Characteristics and Outcomes of Hydralazine-induced ANCA-associated Vasculitis. a Single Center Retrospective Cohort Analysis from the US

    Muhammad Shamim1, Mazen Allouni2, Haseeb Chaudhary3, Ansaam Daoud4, Loai Dweik5, Hashim Syed6 and Omer Pamuk7, 1University Hospitals/ Case Western Reserve University, Cuyahoga Falls, OH, 2Case Western Reserve, University Hospitals, Cleveland Medical Center, Cleveland, OH, 3Case Western Reserve University, Westlake, OH, 4Case Western Reserve University/University Hospitals, Akron, OH, 5Cleveland Clinic Akron General Internal Medicine, Akron, OH, 6Case Western/ UH, Cleveland, 7University Hospitals Cleveland Medical Center/ Case Western Reserve University, Cleveland, OH

    Background/Purpose: Hydralazine-induced ANCA-associated vasculitis (HIAAV) is a rare clinical problem.  There is paucity of data regarding clinical features, treatment, and prognosis of hydralazine-induced AAV in…
  • Abstract Number: 0269 • ACR Convergence 2024

    Delphi Survey to Establish Consensus on the OMERACT Core Domain Set for Long-Term Studies of Calcium Pyrophosphate Deposition Disease

    Yiling Zhang1, Sara Tedeschi2, Abhishek Abhishek3, Owen Hensey4, David Grossberg5, Ken Cai6, Beverley Shea7, Jasvinder Singh8, Robin Christensen9, Teodora Serban10, Edoardo Cipolletta11, Konstantinos Parperis12, César Díaz13, Geraldine McCarthy14, Fabio Becce15, Tamer A Gheita16, Silvia Sirotti17, Sara Nysom Christiansen18, Luis Coronel Tarancon19, Lisa Stamp20, Yousra H Abdel-Fattah21, Tristan Pascart22, Georgios Filippou17, Lih En Hong23, John FitzGerald24 and Nicola Dalbeth1, 1University of Auckland, Auckland, New Zealand, 2Brigham and Women's Hospital, Boston, MA, 3University of Nottingham, Nottingham, United Kingdom, 4OMERACT patient research partner, Dublin, Ireland, 5OMERACT patient research partner, Maryland, 6Westmead Hospital, Sydney, New South Wales, Australia, 7Ottawa Hospital Research Institute, Ottawa, ON, Canada, 8Baylor College of Medicine, Birmingham, AL, 9Musculoskeletal Statistics Unit, The Parker Institute, Copenhagen, Denmark, 10Ospedale La Colletta, Bucharest, Romania, 11Polytechnic University of Marche, Ancona, Italy, 12University of Cyprus Medical School, Nicosia, Cyprus, 13Hospital de la Santa Creu i Sant Pau, Barcelona, Spain, 14Mater Misericordiae University Hospital, Dublin, Ireland, 15Lausanne University Hospital (CHUV), Lausanne, Switzerland, 16Rheumatology Department, Faculty of Medicine, Cairo University, Cairo, Egypt, 17IRCCS Galeazzi - Sant'Ambrogio Hospital, Milan, Italy, 18Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, Denmark., Glostrup, Denmark, 19Image and Technics Unit, Department of Rheumatology. Hospital Universitari Vall d’Hebron, Barcelona, Spain, 20University of Otago, Christchurch, Christchurch, New Zealand, 21Alexandria University, Alexandria, Egypt, 22Lille Catholic University, Lille, France, 23Royal Adelaide Hospital, Unley Park, South Australia, Australia, 24UCLA, Los Angeles, CA

    Background/Purpose: To agree on important domains for the Outcome Measures in Rheumatology (OMERACT) core domain set for long-term studies of calcium pyrophosphate deposition (CPPD) disease.Methods:…
  • Abstract Number: 0542 • ACR Convergence 2024

    Impact of Peripheral Arthritis on Disease Activity Outcomes in Patients with Axial Spondyloarthritis, Peripheral Spondyloarthritis and Psoriatic Arthritis. Data from the ASAS-PerSpA Study

    Clementina López Medina1, Sofia Ramiro2, Dafne Capelusnik3 and Anna Molto4, 1Reina Sofia University Hospital, Cordoba, Spain, 2Leiden University Medical Center, Bunde, Netherlands, 3Tel Aviv Sourasky Medical Center, Ramat Gan, Israel, 4Groupe Hospitalier Cochin, AP-HP, Paris, France

    Background/Purpose: Patients with spondyloarthritis (SpA) can present with several phenotypes (i.e., axial SpA (axSpA), peripheral SpA (pSpA) and Psoriatic Arthritis (PsA)) and peripheral arthritis can…
  • Abstract Number: 0659 • ACR Convergence 2024

    Obinutuzumab Benefits Patients with Active Lupus Nephritis Irrespective of Baseline Proteinuria Severity: A Post Hoc Analysis of a Phase II Trial

    Richard Furie1, Jorge A. Ross Terres2, Elsa Martins3, Imran Hassan4, Thomas Schindler3, Jay Garg5, William F. Pendergraft III6, Ana Malvar7 and Brad Rovin8, 1Northwell Health, Manhasset, NY, 2Genentech, Inc,, San Francisco, 3F. Hoffmann-La Roche Ltd, Basel, Switzerland, 4Hoffmann-La Roche Ltd, Mississauga, Canada, 5Genentech, Inc., South San Francisco, CA, 6Genentech, Inc., Chapel Hill, NC, 7Organización Médica de Investigación, Buenos Aires, Argentina, 8The Ohio State University, Columbus, OH

    Background/Purpose: Lupus nephritis (LN) is the most common severe organ-threatening manifestation of systemic lupus erythematosus (SLE). The randomized, placebo-controlled, Phase II NOBILITY trial (NCT02550652) demonstrated…
  • Abstract Number: 0857 • ACR Convergence 2024

    Exploring Clinical Outcomes of Patients with Cardiac Sarcoidosis on TNF Inhibitors: A Nationwide Retrospective Cohort Study

    Yurilu Gonzalez Moret1, Diego Lema2 and Fabian Rodriguez Quinonez3, 1Jefferson Einstein Hospital, Philadelphia, PA, 2Universidad Central de Venezuela, University of Wisconsin, Philadelphia, PA, 3Einstein Medical Center Philadelphia, Philadelphia, PA

    Background/Purpose: Immunosuppressive therapy, including Tumor necrosis factor inhibitors (TNFi), is commonly used in the treatment of various inflammatory conditions, including extracardiac sarcoidosis. However, the use…
  • Abstract Number: 1180 • ACR Convergence 2024

    Relationship Between Changes in Physical Activity and Early Onset Knee Osteoarthritis in Individuals After ACL Reconstruction

    David Werner1, Yvonne Golightly1, Michael Rosenthal1, Balasrinivasa Sajja1, Christopher Wichman1, Melissa Manzer2, Matthew Tao1 and Elizabeth Wellsandt1, 1University of Nebraska Medical Center, Omaha, NE, 2Private Practice, Omaha

    Background/Purpose: Low physical activity levels are associated with osteoarthritis (OA) development and progression in individuals at risk for OA development. Including both structural and symptomatic…
  • Abstract Number: 1527 • ACR Convergence 2024

    Comparative Harms in Patients with Systemic Lupus Erythematosus Treated with Anifrolumab or Belimumab: A Multicenter Cohort Study Using the TriNetX Research Network

    Hsin-Hua Chen, Division of Allergy, Immunology and Rheumatology, Taichung Veterans General Hospital, Taichung, Taiwan (Republic of China)

    Background/Purpose: Belimumab and anifrolumab, biologic therapies, have shown to improve systemic lupus erythematosus (SLE) outcomes in clinical trials, but there is a lack of real-world…
  • Abstract Number: 1977 • ACR Convergence 2024

    Three-dimensional Stereophotogrammetry Has Utility in Tracking Upper Eyelid Involvement and Overall Disease Worsening in Patients with Craniofacial Localized Scleroderma

    Tyler Cepica1, Jennifer Foster2, Priya Sarlashkar2, Rami Hallac3 and Heidi Jacobe2, 1University of Texas Southwestern Medical School, Benbrook, TX, 2The University of Texas Southwestern Medical Center, Department of Dermatology, Dallas, TX, 3The University of Texas Southwestern Medical Center, Department of Pastic Surgery, Dallas, TX

    Background/Purpose: Craniofacial localized scleroderma’s (LoS) indolent and subtle course poses challenges in quantifying disease progression. Traditional serial photography and the Localized Scleroderma Cutaneous Assessment Tool…
  • Abstract Number: 2246 • ACR Convergence 2024

    Safety and Efficacy of Cannabidiol in Rheumatoid Arthritis Patients: A Phase 1B Pilot Randomized Placebo Controlled Trial

    Veena Ranganath1, Holly Wilhalme2, Nicolette Morris3, Jenny Brook2, Mihaela Taylor1, Howard Yang1, Tanaz Kermani4, Thanda Aung2, Brian Skaggs1, David Elashoff5 and ziva Cooper6, 1UCLA, Los Angeles, CA, 2UCLA, Los Angeles, 3The University of Queensland Medical School, Ochsner Clinical School, New Orleans, LA, 4University of California Los Angeles, Santa Monica, CA, 5UCLA Department of Medicine Statistics Core, Los Angeles, 6UCLA Center for Cannabis and Cannabinoids, Semel Institute for Neuroscience & Human Behavior, Dept of Psychiatry and Biobehavioral Sciences, Dept of Anesthesiology and Perioperative Medicine, Los Angeles

    Background/Purpose: There is no cure for rheumatoid arthritis (RA) and remission rates vary greatly 10-60%; thus, there is an unmet need for safe adjunctive therapeutic…
  • Abstract Number: 2501 • ACR Convergence 2024

    Long-term Remission off Therapy (LTROT) Is Possible in Non-infectious Aortitis with DMARDs with Low Risk of Secondary Adrenal Insufficiency

    Rohit Vijjhalwar1, Vithushanan Ketheeswaranathan2, Aman More2, Rajinder Andev3 and Shirish Dubey4, 1University of Oxford, Staines, United Kingdom, 2Medical Sciences Division, University of Oxford, Oxford, United Kingdom, 3Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom, 4Oxford University Hospitals NHS FT, Oxford, United Kingdom

    Background/Purpose: Non-infectious Aortitis is a rare form of large vessel vasculitis which has a high risk of complications1. There is limited data on the management…
  • Abstract Number: 0290 • ACR Convergence 2024

    Deucravacitinib Long-term Efficacy Through 4 Years in Week 16 Placebo Crossover Patients in the Phase 3 POETYK PSO-1, PSO-2, and LTE Program

    Mark Lebwohl1, Richard Warren2, Shinichi Imafuku3, Jerry Bagel4, April W. Armstrong5, Thierry Passeron6, Subhashis Banerjee7, Renata M. Kisa8, Matthew J. Colombo7, Thomas Scharnitz8, Kim Hoyt8, Diamant Thaçi9 and Andrew Blauvelt10, 1Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY, 2Dermatology Centre, Northern Care Alliance NHS Foundation Trust and NIHR Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom, 3Fukuoka University Hospital Faculty of Medicine, Fukuoka, Japan, 4Psoriasis Treatment Center of New Jersey, East Windsor, 5University of California Los Angeles, Los Angeles, 6Université Côte d’Azur, University Hospital of Nice, Nice, France, 7Bristol Myers Squibb, Princeton, NJ, 8Bristol Myers Squibb, Princeton, 9Institute and Comprehensive Center for Inflammation Medicine, University of Lübeck, Lübeck, Schleswig-Holstein, Germany, 10Oregon Medical Research Center, Portland, OR

    Background/Purpose: Deucravacitinib, an oral, selective, allosteric tyrosine kinase 2 inhibitor, is approved in the US, EU, and other countries for treatment of adults with moderate…
  • Abstract Number: 0543 • ACR Convergence 2024

    Impact of Peripheral Manifestations on Function, Health, and Work Productivity in Patients with Axial Spondyloarthritis, Peripheral Spondyloarthritis and Psoriatic Arthritis. Data from the ASAS-PerSpA Study

    Clementina López Medina1, Anna Molto2, Dafne Capelusnik3 and Sofia Ramiro4, 1Reina Sofia University Hospital, Cordoba, Spain, 2Groupe Hospitalier Cochin, AP-HP, Paris, France, 3Tel Aviv Sourasky Medical Center, Ramat Gan, Israel, 4Leiden University Medical Center, Bunde, Netherlands

    Background/Purpose: Peripheral musculoskeletal manifestations can occur either concomitantly with axial disease or independently in patients with spondyloarthritis (SpA). However, it is not known whether the…
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