Abstracts tagged "Osteoarthritis"

Abstract Number: 2372 • 2016 ACR/ARHP Annual Meeting
Effect of Oxytocin on Osteoarthritis
christian roux¹, astrid pinzano², didier Pisani³, Patricia panaia-Ferrari⁴, eric Fontas⁵, hedi Ben Yahia⁶, damien ambrosetti⁷, jean-François michiels⁸, veronique Breuil⁹ and ez Zoubir Amri¹⁰, ¹Rheumatology, LAMHESS laboratory, sofia antipolis university, CHU Pasteur 2, Nice, France, nice, France, ²IMoPA Ingénierie Moléculaire et Physiopathologie Articulaire, University nancy lorraine, UMR7365 CNRS-UL, Nancy, France, ³CNRS UMR7277, Inserm U1091, UNS Université Nice Sophia Antipolis Parc Valrose, nice, France, ⁴IBiology and immunology laboratory, university nice sofia antipolis, nice, France, ⁵Direction recherche clinique, CHU de Nice, france, Nice, France, ⁶iBV - Institut de Biologie Valrose. Nice, Nice, France, ⁷Department anatomopathology, nice. university nice sofia antipolis, nice, France, ⁸department anatomo-pathology, Nice, university nice sofia antipolis, Nice, France, ⁹Rheumatology department, Nice, France, ¹⁰CNRS UMR7277, Inserm U1091, UNS Université Nice Sophia Antipolis Parc Valrose, Nice, France
Background/Purpose: The relationship between oxytocine (OT) and osteoarthritis (OA) is poorly studied and remains unknown. However the subchondral bone is considered as a major player in…
Abstract Number: 1099 • 2016 ACR/ARHP Annual Meeting
Synovial Exosomes Induce Osteoclast Differentiation in Rheumatoid arthritis
Ji Eun Song¹, Ji Hye Shin¹, Ki Won Moon², Se Hui Shon¹, Ji Soo Park³, Eun Bong Lee³, Yeong Wook Song^1,3 and Eun Young Lee³, ¹Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, and College of Medicine or College of Pharmacy, Seoul National University, Seoul, Republic of Korea, Seoul, Korea, The Republic of, ²Department of Internal Medicine, Kangwon National University Hospital, Chuncheon, Republic of Korea, Chuncheon, Korea, The Republic of, ³Division of Rheumatology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea, Seoul, Korea, The Republic of
Background/Purpose: Exosomes are small membrane vesicles (40-150 nm) of endocytic origin secreted by many types of cells and engage in cell-to-cell communication by transferring proteins,…
Abstract Number: 3048 • 2016 ACR/ARHP Annual Meeting
Pain Severity As a Mediator of the Effect of Depressive Symptoms on Physical Performance in Knee Osteoarthritis
Alan Rathbun¹, Michelle Shardell², Michelle S. Yau³, Mona Baumgarten⁴, Elizabeth Stuart⁵ and Marc Hochberg⁶, ¹Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, ²Translational Gerontology Branch, National Institute on Aging, Baltimore, MD, ³Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ⁴University of Maryland School of Medicine, Baltimore, MD, ⁵Mental Health, Biostatistics, and Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, ⁶Department of Medicine, University of Maryland School of Medicine, Baltimore, MD
Background/Purpose: Depression is a significant comorbidity of knee osteoarthritis (OA) that occurs in approximately 20% of OA patients. Depressive symptoms are associated with both subsequent…
Abstract Number: 1154 • 2016 ACR/ARHP Annual Meeting
Promoting Self-Management Techniques for Osteoarthritis Pain: a Pilot Study of Nurse Practitioner Led Coping Skills Training
Christine A. Stamatos^1,2 and Particia Bruckenthal³, ¹Medicine, Division Rheumatology, Northwell Health, Great Neck, NY, ²Northwell Health, Great Neck, NY, ³School of Nursing, Stony Brook University, Stony Brook, NY
Background/Purpose: Arthritis is the leading cause of chronic pain and disability in the United States. Two thirds of patients report inadequate pain control. Coping Skills Training…
Abstract Number: 3253 • 2016 ACR/ARHP Annual Meeting
Minimum Physical Function Needed to Walk 6000 Steps/Day in People with Knee Osteoarthritis
Hiral Master¹, Louise Thoma¹, Meredith Christiansen¹, Emily Polakowski¹, Laura Schmitt¹ and Daniel White², ¹Physical Therapy and Biomechanics and Movement Science, University of Delaware, Newark, DE, ²Department of Physical Therapy, University of Delaware, Newark, DE
Title: Minimum Physical Function Needed To Walk 6000 steps/day In People With Knee Osteoarthritis. Background/Purpose: Adopting a physically active lifestyle provides major health benefits to…
Abstract Number: 1203 • 2016 ACR/ARHP Annual Meeting
Differential Synovial Expression Patterns in Early Osteoarthritis Predict Pain and Progression of Joint Damage
Arjen B. Blom¹, Martijn H. van den Bosch¹, Hans Cats², F van den Hoogen³, Floris PJ Lafeber⁴, Wim B. van den Berg¹, Peter L. van Lent¹ and Peter M. van der Kraan¹, ¹Experimental Rheumatology, Radboud university medical center, Nijmegen, Netherlands, ²Hengstdal 3, Sint Maartenskliniek, Ubbergen, Netherlands, ³Rheumatology, Radboud UMC, Nijmegen, Netherlands, ⁴Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, Netherlands
Background/Purpose: The cause for chronic pain in OA is largely unknown. Over 50% of osteoarthritis (OA) patients show synovial inflammation, even at early stages of…
Abstract Number: 928 • 2015 ACR/ARHP Annual Meeting
The Value of Early Ultrasound-Detected Osteophytes in Hand Osteoarthritis: Predicting the Future
Alexander Mathiessen¹, Barbara Slatkowsky-Christensen², Tore K. Kvien³, Ida K. Haugen⁴ and Hilde Berner Hammer², ¹Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ²Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ³Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ⁴P.O. Box 23, Diakonhjemmet Hospital, Vinderen, Norway
Background/Purpose: Ultrasound is more sensitive than conventional radiographs in detecting small osteophytes in hand osteoarthritis (OA). Osteophytes can be seen prior to joint space narrowing…
Abstract Number: 2411 • 2015 ACR/ARHP Annual Meeting
Patient Preference for Using Technology to Track and Self-Manage Osteoarthritis
Laura Khurana, Ellen Durand, Sarah Gary, Tony Otero, Chris Hall and Susan Dallabrida, ERT, Boston, MA
Background/Purpose: Active and consistent self-management is essential for patients suffering from chronic diseases to improve their health. Electronic clinical (eClinical) technology may improve how patients…
Abstract Number: 951 • 2015 ACR/ARHP Annual Meeting
Comparative Effectiveness of Tai Chi Versus Physical Therapy in Treating Knee Osteoarthritis: A Randomized, Single-Blind Trial
Chenchen Wang^1,2, Christopher Schmid³, Maura D. Iversen⁴, William F. Harvey², Roger A. Fielding⁵, Jeffrey B. Driban², Lori Lyn Price⁶, John B. Wong^7,8, Kieran Reid⁵, Ramel Rones⁹ and Timothy E. McAlindon², ¹Rheumatology, Tufts Medical Center, Bosotn, MA, ²Rheumatology, Tufts Medical Center, Boston, MA, ³Brown University School of Public Health, Providence, RI, ⁴Northeastern University,, Boston, MA, ⁵Nutrition, Exercise Physiology and Sarcopenia Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, ⁶Clinical Care Research, Tufts Medical Center, Boston, MA, ⁷Tufts Medical Center, Boston, MA, ⁸Clinical Decision Making, Tufts Medical Center, Boston, MA, ⁹Center for Mind–Body Therapies, Boston, MA
Background/Purpose: Knee osteoarthritis (OA) causes long-term pain and no effective treatments currently exist. Previous trials demonstrated that Tai Chi can improve both physical and mental…
Abstract Number: 2412 • 2015 ACR/ARHP Annual Meeting
Assessment and Comparison of Responsiveness of Four Patient Reported Outcome Measures to Assess Physical Function in Patients with Knee Osteoarthritis: WOMAC-PF Subscale Responds Best
Elien A.M. Mahler¹, Nienke Cuperus², Johannes W J Bijlsma³, Thea Vliet Vlieland⁴, Frank H.J. van den Hoogen⁵, Alfons den Broeder⁵ and Cornelia H.M. van den Ende¹, ¹Department of Rheumatology, Sint Maartenskliniek, Nijmegen, Netherlands, ²Rheumatology Department, Sint Maartenskliniek, Nijmegen, Netherlands, ³Rheumatology and Clinical Immunology, ARC Amsterdam; UMC Utrecht, Utrecht, Netherlands, ⁴Rheumatology, Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁵Rheumatology, Sint Maartenskliniek, Nijmegen, Netherlands
Background/Purpose: Although physical function is one of the core outcome domains in knee osteoarthritis (OA), the ability of a measurement instrument to detect changes over…
Abstract Number: 953 • 2015 ACR/ARHP Annual Meeting
Effectiveness of a Progressive Resistence Strength Programme on Hand Osteoarthritis: A Randomized Crontrolled Trial
Michele V. Nery¹, Anamaria Martinez², Fabio Jennings³, Marcelo Souza² and Jamil Natour², ¹Rheumatology Division, Universidade Federal de Sao Paulo, Sao Paulo, Brazil, ²Rheumatology Division, Federal University of Sao Paulo, Sao Paulo, Brazil, ³Disciplina de reumatologia, Universidade Federal de São Paulo, Sao Paulo, Brazil
Background/Purpose: Hand osteoarthritis (OA) is highly prevalent, affecting 55-70% of the population over 55 years with an age-related progressive increase. The OA of interphalangeal (IF)…
Abstract Number: 2617 • 2015 ACR/ARHP Annual Meeting
Serum 14-3-3eta Protein Elevation in Osteoarthritis Suggests Misclassification or Concurrent Inflammatory Arthritis
Olga S. Zhukov¹, Jonnielyn G. Rivera¹, Rania W. Abolhosn¹, Robert J. Lagier², Charles M. Rowland³, Joanna M. Popov¹, Kaleb Michaud⁴ and Stanley J. Naides¹, ¹Immunology, Quest Diagnostics Nichols Institute, San Juan Capistrano, CA, ²Research Support, Alameda, Quest Diagnostics Alameda, Alameda, CA, ³Research Support, Quest Diagnostics Alameda, Alameda, CA, ⁴Rheumatology & Immunology, University of Nebraska Medical Center and National Data Bank, Omaha, NE
Background/Purpose: Tissue distribution of the chaperonin 14-3-3η (eta) is limited to synovial tissue and brain. Synovium releases proinflammatory 14-3-3η into synovial fluid and serum in…
Abstract Number: 1150 • 2015 ACR/ARHP Annual Meeting
Novel Chitosan Hydrogels for the Treatment of Osteoarthritis: Mechanical Support, Lubrication and Prevention of Cartilage Degradation in a Rabbit Model of Osteoarthritis
Yves Henrotin^1,2, Frédéric Oprenyeszk¹, Fanny Comblain³, Jean-Emile Dubuc⁴, Christelle Boileau⁵, Mickaël Chausson⁶, Renaud Lecler⁶, Guillem Rocasalbas⁶, Pierre Douette⁶ and Sandrine Gautier⁶, ¹Bone and Cartilage Research Unit, Arthropôle Liege, University of Liege, Liege, Belgium, ²Physical Therapy and Rehabilitation Department, Princess Paola Hospital, Marche-en-Famenne, Belgium, ³University of Liège, Bone and Cartilage Research Unit, Arthropôle Liege, University of Liege, Liege, Belgium, ⁴Clinical University Saint Luc, Orthopaedic Department, Clinical University Saint Luc, Brussels, Belgium, ⁵Artialis S.A.,11 Avenue de l’Hôpital, Tour Giga+3, Liege, Belgium, ⁶Synolyne Pharma, rue Haute Claire 4, Herstal, Belgium
Background/Purpose: Chitosan, a glucosamine polysaccharide, is a good candidate for viscosupplementation in OA joints. Herein, we report the physico-chemical properties and the effects of an…
Abstract Number: 3086 • 2015 ACR/ARHP Annual Meeting
The Same Multidimensional Patient Health Assessment Questionnaire Used to Assess RAPID3 in Rheumatoid Arthritis, Osteoarthritis and Other Rheumatic Diseases Can Provide Quantitative Clues to Recognize and Document Comorbid Fibromyalgia
Kathryn A. Gibson¹, Annie Huang² and Theodore Pincus², ¹Liverpool Hospital, Liverpool, Australia, ²Rheumatology, Rush University Medical Center, Chicago, IL
Background/Purpose: An MDHAQ/RAPID3 (Multidimensional Health Assessment Questionnaire/Routine Assessment of Patient Index Data) is a 2 sided, 1 page questionnaire which is completed by patients in…
Abstract Number: 126 • 2015 ACR/ARHP Annual Meeting
Patients with Osteoarthritis and Rheumatoid Arthritis Seen at 4 Different Routine Rheumatology Care Sites at This Time Have Similar and Patient and Physician Global Estimates of Severity, and Scores for Functional Disability, Pain, and RAPID3
Carlos El-Haddad¹, Isabel Castrejón², Kathryn A. Gibson³, Yusuf Yazici⁴, Martin Bergman⁵ and Theodore Pincus², ¹Rheumatology, Liverpool Hospital, NSW, Australia, ²Rheumatology, Rush University Medical Center, Chicago, IL, ³Liverpool Hospital, Liverpool, Australia, ⁴NYU Hospital for Joint Diseases, New York, NY, ⁵Division of Rheumatology, Taylor Hospital, Ridley Park, PA
Background/Purpose: RA generally is regarded by physicians and the public as a more severe problem than OA. However, OA has been ranked as the 11th…

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