Abstracts tagged "Osteoarthritis"

Abstract Number: 2133 • 2016 ACR/ARHP Annual Meeting
Simulation of Cartilage Damage in Osteoarthritis Using Patient-Derived Induced Pluripotent Stem Cells
Seung Min Jung¹, Yoojun Nam², Yeri Alice Rim², Yong-Beom Park¹, Seung-Ki Kwok³, Sung-Hwan Park⁴ and Ji Hyeon Ju⁵, ¹Division of Rheumatology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, South Korea, ²Division of Rheumatology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea, The Republic of, ³[email protected], Division of Rheumatology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, South Korea, ⁴Division of Rheumatology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, South Korea, ⁵Division of Rheumatology, Department of Internal Medicine,, College of Medicine, The Catholic University of Korea, Seoul, South Korea
Background/Purpose: Osteoarthritis (OA) is a degenerative joint disease, leading to pain and functional limitation. Although OA is a most common form of musculoskeletal disease, the…
Abstract Number: 2179 • 2016 ACR/ARHP Annual Meeting
What Are the Risk Factors for Knee Pain, Radiographic Knee Osteoarthritis and Total Knee Replacement in Professional Footballers?
Sanjay M Parekh^1,2, Gwen S Fernandes^1,2,3, Jonathan P Moses^1,2, Colin Fuller⁴, Brigitte Scammell^1,2,3, Mark Batt^1,2,3, Weiya Zhang^1,2,3 and Michael Doherty^1,2,3, ¹Division of Rheumatology, Orthopaedics and Dermatology, School of Medicine, University of Nottingham, Nottingham, United Kingdom, ²Arthritis Research UK Centre for Sports, Exercise and Osteoarthritis, Nottingham, United Kingdom, ³Arthritis Research UK Pain Centre, Nottingham, United Kingdom, ⁴Colin Fuller Consultancy Ltd, Nottingham, United Kingdom
Background/Purpose: Football is the world’s most popular team sport. However, whether professional footballers have a higher prevalence of knee injury and subsequently, knee pain (KP),…
Abstract Number: 116 • 2016 ACR/ARHP Annual Meeting
Racial Differences in Self-Reported Pain and Disability: A Longitudinal Study of Knee Osteoarthritis
Ernest Vina¹, Di Ran², Erin Ashbeck² and C. Kent Kwoh³, ¹Rheumatology, University of Arizona, Tucson, AZ, ²University of Arizona, Tucson, AZ, ³Rheumatology, University of Arizona, College of Medicine, Tucson, AZ
Background/Purpose: Pain and disability from knee osteoarthritis (KOA) has been reported to be greater among African-Americans (AAs) than Whites (WHs), though progression in KOA-related…
Abstract Number: 2183 • 2016 ACR/ARHP Annual Meeting
The Electronic Osteoarthritis Knee and Hip Quality of Life (OAKHQOL) Questionnaire: A Useful and Valid Alternative to Measure Health-Related Quality of Life in Knee Osteoarthritis
Maud Wieczorek¹, Christine Rotonda^2,3, Francis Guillemin^4,5 and Anne-Christine Rat^4,5,6, ¹Apemac EA4360, Nancy, University of Lorraine, Vandoeuvre-lès Nancy, France, ²Apemac EA4360, Nancy, University of Lorraine, Vandoeuvre-lès-Nancy, France, ³CIC-1433 Epidémiologie Clinique, nancy, Inserm, Vandoeuvre-lès-Nancy, France, ⁴Apemac EA 4360, Nancy, University of Lorraine, Vandoeuvre-lès-Nancy, France, ⁵CIC-1433 Epidémiologie Clinique, Nancy, Inserm, Vandoeuvre-lès-Nancy, France, ⁶Rheumatology Department, CHRU Nancy, Vandoeuvre-lès-Nancy, France
Background/Purpose: With the growing development of new technologies in clinical research, an electronic version of the OsteoArthritis Knee and Hip Quality Of Life (OAKHQOL), the…
Abstract Number: 295 • 2016 ACR/ARHP Annual Meeting
Efficacy and Safety of Fasinumab for Osteoarthritic Pain in Patients with Moderate to Severe Osteoarthritis of the Knees or Hips
Jennifer Maloney¹, Alan Kivitz², Thomas J. Schnitzer³, Paula Dakin¹, Catherine Stehman-Breen¹ and Greg Geba¹, ¹Regeneron Pharmaceuticals, Inc., Tarrytown, NY, ²Altoona Center for Clinical Research, Duncansville, PA, ³Northwestern University, Chicago, IL
Background/Purpose: Osteoarthritis (OA) is an important cause of chronic pain in older adults. Fasinumab is a fully-human, high-affinity monoclonal antibody directed against the nerve growth…
Abstract Number: 2221 • 2016 ACR/ARHP Annual Meeting
Recognition of Secondary Fibromyalgia Using an Index of 3 Components of the Multi-Dimensional Health Assessment Questionnaire: 90% Agreement with ACR Criteria for Fibromyalgia
Kathryn Gibson^1,2, Isabel Castrejón³, Theodore Pincus³ and Katherine J. Bryant⁴, ¹Liverpool Hospital, Sydney, Sydney, Australia, ²Ingham Research Institute, Liverpool, Australia, ³Rheumatology, Rush University Medical Center, Chicago, IL, ⁴University of New South Wales, Sydney, Australia
Background/Purpose: Secondary fibromyalgia (FM) is seen 15-20% of patients with rheumatoid arthritis (RA) (1), systemic lupus erythematosus (SLE) (2), osteoarthritis (OA), and other rheumatic diseases.…
Abstract Number: 314 • 2015 ACR/ARHP Annual Meeting
A Double-Blind, Randomized, Controlled, Four Parallel Arm, Dose-Finding Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of Single Intra-Articular (IA) Injections of Fasitibant in Patients with Symptomatic OA of the Knee
Claudia Gabriele Werner¹, Karel Pavelka², Andrea Nizzardo³, Cristina Rossi³, Simona Scartoni³, Maria Paola Contini³, Serena di Molfetta³, Monica Bertolotti³, Angela Capriati³ and Carlo Alberto Maggi⁴, ¹Clinical Research, A. Menarini Research & Business Service GmbH, Berlin, Germany, ²Institute of Rheumatology and Department of Rheumatology, First Faculty of Medicine, Charles University, Prague, Czech Republic, ³Clinical Research Department, Menarini Ricerche S.p.A., Florence, Italy, ⁴Menarini Ricerche S.p.A., Florence, Italy
Background/Purpose: Fasitibant (FAS) is a competitive, potent and selective antagonist of the bradykinin B2 receptor administered IA for SOAK. In response to positive outcomes in…
Abstract Number: 2164 • 2015 ACR/ARHP Annual Meeting
Burden of Symptomatic Knee Osteoarthritis in the United States: Impact of Race/Ethnicity, Age and Sex
Bhushan Deshpande¹, Jeffrey N. Katz², Daniel H. Solomon², Edward H. Yelin³ and Elena Losina², ¹Orthopaedic and Arthritis Center for Outcomes Research, Brigham and Women's Hospital, Boston, MA, ²Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ³University of California, San Francisco, San Francisco, CA
Background/Purpose : Growing evidence suggests that the prevalence and incidence of knee OA is rising, partially due to increasing life expectancy and the growing obesity…
Abstract Number: 322 • 2015 ACR/ARHP Annual Meeting
Reduction of Treatment Needed for Knee Osteoarthritis after Bariatric Surgery
Evan Wilder¹, Janice Lin¹, Fernando Bomfim¹, Thayer Mukherjee¹, Lucy O'Shaughnessy¹, Lauren Browne¹, Myriam Weill¹, Kevin Gernavage¹, Farah Taufiq¹, Renata La Rocca Vieira², Christine Ren-Fielding³, Manish Parikh⁴, Steven B. Abramson⁵ and Jonathan Samuels⁶, ¹NYU Langone Medical Center, New York, NY, ²Department of Radiology, NYU Langone Medical Center, New York, NY, ³Department of Surgery, New York University School of Medicine, New York, NY, ⁴Department of Surgery, NYU Langone Medical Center, New York, NY, ⁵Dept of Rheumatology/Medicine, Hosp for Joint Diseases/NYU, New York, NY, ⁶Rheumatology, NYU - Hospital for Joint Diseases, New York, NY
Background/Purpose: Medical treatment for knee osteoarthritis (KOA) can be limited and risk morbidity. Weight loss reduces the arthritis burden and may preclude aggressive treatment. Bariatric…
Abstract Number: 2248 • 2015 ACR/ARHP Annual Meeting
Knee Pain Burden Is Associated with Decreased Motor Performance: Data from the Osteoarthritis Initiative
Javad Razjouyan¹, Bijan Najafi², Erin Ashbeck³, Dorothy D. Dunlop⁴, Julia (Jungwha) Lee⁵, Lynn Hamilton³ and C. Kent Kwoh⁶, ¹Consortium on Advanced Motion Performance (iCAMP), Department of Surgery, University of Arizona, Tucson, AZ, ²Department of Surgery and Department of Biomedical Engineering, University of Arizona, Tucson, AZ, ³Arthritis Center, University of Arizona, Tucson, AZ, ⁴Institute for Healthcare Studies, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁵Department of Preventive Medicine, Biostatistics Collaboration Center, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁶Rheumatology, University of Arizona, Tucson, AZ
Background/Purpose: Knee pain is the presenting symptom in knee osteoarthritis (OA), but the impact of knee pain burden in OA has been understudied. We examined…
Abstract Number: 336 • 2015 ACR/ARHP Annual Meeting
Lack of Uniform Diagnostic Criteria for Erosive OA: A Systematic Review
Supraja Yeturi¹, Payal Patel², Gazeley David² and Ann K. Rosenthal³, ¹Rheuamtology, Medical college of Wisconsin, Milwaukee, WI, ²Medical College of Wisconsin, Milwaukee, WI, ³Div of Rheumatology, Medical College of WI, Milwaukee, WI
Background/Purpose: Erosive osteoarthritis (EOA) is a potentially important subtype of osteoarthritis initially described in the 1960s. Since that time, EOA has been the focus of…
Abstract Number: 2325 • 2015 ACR/ARHP Annual Meeting
Quantitative Clues to Recognize and Document Comorbid Fibromyalgia in Routine Care of Patients with Other Rheumatic Diagnoses on a 10 Cm Distress Visual Analog Scale Found on 1-Page Physician Rheumetric Checklist
Kathryn A. Gibson¹, Katherine J. Bryant² and Theodore Pincus³, ¹Liverpool Hospital, Liverpool, Australia, ²University of New South Wales, Sydney, Australia, ³Rheumatology, Rush University Medical Center, Chicago, IL
Background/Purpose: A physician global estimate (DOCGL) is commonly used to assess patients with rheumatic diseases. Fibromyalgia (FM) has been reported as a comorbidity in 10-35%…
Abstract Number: 337 • 2015 ACR/ARHP Annual Meeting
Construct Validity of the Doyle Index in the Outcome Domain of Joint Activity in Hand Osteoarthritis Patients
W. Damman¹, R. Liu¹, M.C. Kortekaas^1,2, F.R. Rosendaal³, D. van der Heijde⁴ and M. Kloppenburg¹, ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Department of Rheumatology, Flevoziekenhuis, Almere-Stad, Netherlands, ³Clinical Epidemiology, Leiden University Medical Center, Leiden, Netherlands, ⁴Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: The Outcome Measures in Rheumatology (OMERACT) working group on hand osteoarthritis (OA) has endorsed a preliminary set of core domains for outcome measures in…
Abstract Number: 2385 • 2015 ACR/ARHP Annual Meeting
Arthritis Management in Primary Care and Adherence to National Guidelines – a Swedish Survey Based on the Canadian Physiotherapists Arthritis Care Questionnaire
Siv Folkhammar Andersson¹, Stefan Bergman^2,3,4 and Ann Bremander^3,4,5, ¹Unit of Rehabilitation, Kalmar County Council, Samrehab, Oskarshamn, Sweden, Oskarshamn, Sweden, ²Primary Health Care Unit, Department of Public Health and Community Medicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden, ³Department of Clinical Sciences, Lund, Section of Rheumatology, Lund University, Lund, Sweden, ⁴FoU Spenshult, Halmstad, Sweden, ⁵School of Business, Engineering and Science, Halmstad University, Halmstad, Sweden
Background/Purpose: For patients with osteoarthritis (OA) physical therapy is recommended first line treatment and performed in primary care while patients with rheumatoid arthritis (RA) may…
Abstract Number: 340 • 2015 ACR/ARHP Annual Meeting
Radiographic Assessment of Hand Osteoarthritis – the Role of Oblique View Images
Kevin Staats¹, Ilse-Gerlinde Sunk¹, Claudia Schueller-Weidekamm², Gabriela Supp³, Birgit Niederreiter⁴, Tanja A. Stamm⁵, Josef S. Smolen⁶ and Klaus Bobacz¹, ¹Medical University of Vienna, Vienna, Austria, ²Department of Radiology, Medical University of Vienna, Vienna, Austria, ³Rheumatology, Medical University of Vienna, Vienna, Austria, ⁴Rheumatology, Internal Medicine III, Medical University of Vienna, Vienna, Austria, ⁵Internal Medicine III, Vienna Medical University, Vienna, Austria, ⁶Dept of Medicine 3, Division of Rheumatology, Medical Univ Vienna, Vienna, Austria
Background/Purpose: To evaluate the role of oblique view images in the radiographic assessment of hand osteoarthritis (HOA).Methods: 159 patients of our HOA cohort were included.…

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