ACR Meeting Abstracts

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Abstracts tagged "Osteoarthritis"

  • Abstract Number: 261 • 2013 ACR/ARHP Annual Meeting

    Concordance Of Hip Pain With Radiographic Hip Osteoarthritis In An Urban US Community: The Framingham Osteoarthritis Study

    Kyu Chan Kim1, David T. Felson2, Katherine D. Linsenmeyer3, Ali Guermazi4, Steven C. Vlad5, Mary M. Clancy6 and Jingbo Niu7, 1Internal Medicine and Rheumatology, Boston Medical Center, Boston, MA, 2Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, 3Internal Medicine, Boston Medical Center, Boston, MA, 4Boston University, Boston, MA, 5Clinical Epidemiology, Boston University, Boston, MA, 6School of Medicine, Boston University, Boston, MA, 7Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA

    Background/Purpose: While it is well known that knee pain and radiographic knee osteoarthritis (OA) are often discordant, little is known of the concordance of hip…
  • Abstract Number: 150 • 2013 ACR/ARHP Annual Meeting

    A Subset Of Osteoarthritis Individuals Has Elevated IL-6 Pathway Activation Associated With Worse Symptoms

    Michael Kuziora1, Zheng Liu2, Brandon W. Higgs2, Philip Brohawn2, Kim Lehmann2, Fernanda Pilataxi2, Katie Streicher2, Lydia Greenlees1, Meina Liang3, Rozanne Lee4, Amy Schneider4, Raffaella Faggioni4, Yihong Yao2 and Koustubh Ranade2, 1Translational Science, MedImmune, LLC, Gaithersburg, MD, 2Translational Sciences, MedImmune, LLC, Gaithersburg, MD, 3Dmpk, MedImmune, LLC, Hayward, CA, 4DMPK, MedImmune, LLC, Hayward, CA

    Background/Purpose:  Elevated levels of the pro-inflammatory cytokine IL-6 have been found in the affected joint of patients with osteoarthritis (OA), although the prevalence of OA…
  • Abstract Number: 2103 • 2013 ACR/ARHP Annual Meeting

    Relationships Between Self-Efficacy, Outcome Expectancy, and Outcomes In Older Adults With Osteoarthritis Of The Knee and Hypertension: Baseline Results

    Elizabeth A. Schlenk1, Deborah Crowley-Lisowski1, Sarah Twerski1, Alice Fallon1, Alyssa Sartore1, Susan Sereika1, Joan Rogers2, G. Kelley Fitzgerald3 and C. Kent Kwoh4, 1School of Nursing, University of Pittsburgh, Pittsburgh, PA, 2School of Health and Rehabilitation Sciences, Occupational Therapy, University of Pittsburgh, Pittsburgh, PA, 3School of Health and Rehabilitation Sciences, Physical Therapy, University of Pittsburgh, Pittsburgh, PA, 4School of Medicine, Department of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA

    Background/Purpose: Staying Active with Arthritis (STAR), an intervention guided by Bandura’s Self-Efficacy Theory, is being investigated in an ongoing clinical trial of an individually delivered,…
  • Abstract Number: 263 • 2013 ACR/ARHP Annual Meeting

    “Generalized Osteoarthritis”: A Systematic Review

    Amanda E. Nelson1, Michael W. Smith2 and Yvonne M. Golightly3, 1University of North Carolina Thurston Arthritis Research Center, Chapel Hill, NC, 2Rheumatology, Saint Luke's Hospitals, Kansas City, MO, 3Gillings School of Global Public Health, Dept of Epidemiology, Thurston Arthritis Research Center, Injury Prevention Research Center, University of North Carolina Dept of Epidemiology, Chapel Hill, NC

    Background/Purpose: To perform a systematic review of definitions, risk factors, and outcomes in "generalized osteoarthritis" (GOA). Methods: We performed a systematic review of Medline literature…
  • Abstract Number: 2108 • 2013 ACR/ARHP Annual Meeting

    Pre- and Postoperative Physical Therapy In Total Hip and Knee Replacement Surgery:  A Multi Center Study

    Wilfred FH Peter1,2, Claire Tilbury3, Rutger Tordoir4, Suzan Verdegaal5, Ron Onstenk6, Menno Benard7, Stephan Vehmeijer8, Enrike van der Linden-van der Zwaag1, Eric Vermeulen1, Rob Nelissen1 and Thea VlietVlieland9, 1Department of Orthopaedics, Leiden University Medical Center, Leiden, Netherlands, 2Reade, center for rehabilitation and rheumatology, Amsterdam, Nicaragua, 3Departement of Orthopedics, Leiden University Medical Center, Leiden, Netherlands, 4Departement of orthopedics, Rijnland Hospital, Leiderdorp, Netherlands, 5Departement of Orthopedics, Rijnland Hospital, Leiderdorp, Netherlands, 6Department of Orthopedics, Het Groene Hart Hospital, Gouda, Netherlands, 7Departement of Orthopedics, Reinier de Graaf Hospital, Delft, Netherlands, 8Department of Orthopedics, Reinier de Graaf Hospital, Delft, Netherlands, 9Department of Orthopaedics, Leids University Medical Center, Leiden, Netherlands

    Background/Purpose: Physical therapy  shown to be effective after Total Hip and Knee Arthroplasty.  Less evidence is available for preoperative physical therapy  in Total Hip and…
  • Abstract Number: 264 • 2013 ACR/ARHP Annual Meeting

    The Proportion Of Knee Osteoarthritis Patients In Southern Sweden That Seek Medical Car

    Aleksandra Turkiewicz1, Maria Gerhardsson de Verdier2, Gunnar Engström3, Stefan Lohmander1 and Martin Englund1, 1Department of Orthopedics, Clinical Sciences Lund, Lund University, Lund, Sweden, 2Astra Zeneca R&D Molndal, Molndal, Sweden, Molndal, Sweden, 3Dept of Cardiovascular epidemiology, Clinical Sciences, Lund University, Lund, Sweden

    Background/Purpose: To provide estimates of the proportion of subjects with knee osteoarthritis (OA) that seek healthcare for knee OA or joint pain within an 8-year…
  • Abstract Number: 1099 • 2012 ACR/ARHP Annual Meeting

    Whole Blood Lead Is Associated with Symptoms, but Not Radiographic Osteoarthritis, in Multiple Joint Sites: The Johnston County Osteoarthritis Project

    Amanda E. Nelson1, Xiaoyan A. Shi2, Todd A. Schwartz3, Jordan B. Renner4, Kathleen L. Caldwell5, Charles G. Helmick6 and Joanne M. Jordan7, 1University of North Carolina Thurston Arthritis Research Center, Chapel Hill, NC, 2SAS Institute, Inc, Cary, NC, 3University of North Carolina Gillings School of Global Public Health, Dept of Biostatistics, Chapel Hill, NC, 4University of North Carolina School of Medicine, Dept of Radiology, Chapel Hill, NC, 5Centers for Disease Control and Prevention, Atlanta, GA, 6National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, 7Thurston Arthritis Research Center, University of North Carolina, Chapel Hill, NC

    Background/Purpose: We have previously identified associations between whole blood lead (Pb) and knee osteoarthritis (OA) and with biomarkers of joint metabolism.  We hypothesized that Pb…
  • Abstract Number: 272 • 2012 ACR/ARHP Annual Meeting

    Interim Safety Analysis of a Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Efficacy Study of Apremilast (CC10004) in Subjects with Erosive Hand Osteoarthritis

    Juergen Rech1, Wolfgang Ochs2, Wolfgang Spieler3, Herbert Kellner4, Ulf Müller-Ladner5, Mathias Grunke6, Matthias Schneider7 and Georg Schett8, 1Department of Internal Medicine 3, University of Erlangen-Nuremberg, Erlangen, Germany, 2Rheumatologist in private practice, Bayreuth, Germany, 3Rheumatology Specialty Practice, Zerbst, Germany, 4Centre for Inflammatory Joint Diseases, Munich, Germany, 5Abt. f. Rheumatologie u. klinische Immunologie, Osteologie, Physikalische Therapie, Kerckhoff-Klinik GmbH, Bad Nauheim, Germany, 6Division of Rheumatology, Medizinische Klinik und Poliklinik IV, University of Munich, Munich, Germany, 7Department of Endocrinology, Diabetes and Rheumatology, Heinrich-Heine-University, Duesseldorf, Germany, 8Dept of Medicine 3, Rheumatology and Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany

    Background/Purpose:  Apremilast is a small molecule,specific phospodiesterase4 inhibitor under investigation for a number of inflammatory conditions, including psoriasis and psoriatic arthritis. We report results of…
  • Abstract Number: 2517 • 2012 ACR/ARHP Annual Meeting

    Inhibition of Notch Signaling Increases the Severity of Experimental Osteoarthritis

    Neng-Yu Lin1, Alfiya Distler1, Christian Beyer2, Clara Dees3, Jingang Huang3, Francesco Dell'Accio4, Oliver Distler5, Georg A. Schett6 and Joerg HW Distler1, 1Department of Internal Medicine III and Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany, 2Department of Internal Medicine 3, Department of Internal Medicine 3 and Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany, 3Department of Internal Medicine 3 and Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany, 4William Harvey Research Institute, Barts and the London Queen Mary's School of Medicine and Dentistry, Centre for Experimental Medicine and Rheumatology, London, United Kingdom, 5Department of Rheumatology and Center of Experimental Rheumatology, University Hospital Zurich, Zurich, Switzerland, 6Dept of Medicine 3, Rheumatology and Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany

    Background/Purpose: Notch signaling is triggered by binding of ligands such as Jagged-1 (Jag-1) to Notch receptors, which results in cleavage of Notch receptors by the…
  • Abstract Number: 1103 • 2012 ACR/ARHP Annual Meeting

    Cumulative Occupational Physical Load As Risk Factor for Knee Osteoarthritis

    Allison M. Ezzat1, Jolanda Cibere2, Mieke Koehoorn3, Eric C. Sayre4 and Linda C. Li5, 1School of Rehabilitation Science, University of British Columbia, Vancouver, BC, Canada, 2Division of Rheumatology, Arthritis Research Centre of Canada, Richmond, BC, Canada, 3University of British Columbia, Vancouver, BC, Canada, 4Arthritis Research Centre of Canada, Vancouver, BC, Canada, 5Department of Physical Therapy, University of British Columbia, Vancouver, BC, Canada

    Background/Purpose: Knee osteoarthritis (OA) results from the interaction of multiple risk factors, one of which may be physically demanding occupations. The purpose of this study…
  • Abstract Number: 248 • 2012 ACR/ARHP Annual Meeting

    Synovial Fluid Leptin Level Is Associated with Residual Pain and Functional Disability One Year After Total Joint Arthroplasty

    Anne Lübbeke1, Gabor J. Puskas1, Axel Finckh2, Domizio Suva1, Sylvette Bas3, Cem Gabay3, Daniel Fritschy1 and Pierre Hoffmeyer1, 1Orthopaedic Surgery, Geneva University Hospitals, Geneva, Switzerland, 2Rheumatology, Geneva University Hospitals, Geneva 14, Switzerland, 3Rheumatology, Geneva University Hospitals, Geneva, Switzerland

    Background/Purpose:  A sizeable number of patients continue to suffer from pain, functional disability and reduced quality of life after total joint arthroplasty (TJA). The etiology…
  • Abstract Number: 2469 • 2012 ACR/ARHP Annual Meeting

    A Virtual Knee Joint Replacement Clinical Endpoint Based On Longitudinal Trends and Thresholds in Koos Knee Pain and Function in Osteoarthritis Initiative Participants

    Robert M. Boudreau1, David J. Hunter2, Zhijie Wang3, Frank Roemer4, Felix Eckstein5, Michael J. Hannon3, Ali Guermazi6 and C. Kent Kwoh7, 1Epidemiology, University of Pittsburgh, Pittsburgh, PA, 2Rheumatology, Institute of Bone and Joint Research, Kolling Institute, University of Sydney, Sydney, Australia, 3Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, 4Radiology, Boston University School of Medicine, Boston, MA, 5Anatomy & Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria, 6Boston University, Boston, MA, 7School of Medicine, Department of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA

    Background/Purpose: Knee joint replacement (KR) is a cost-effective procedure with good long-term outcomes, but has limitations as an endpoint in OA intervention trials. A definition…
  • Abstract Number: 1104 • 2012 ACR/ARHP Annual Meeting

    The Association of Demographic, Modifiable, Structural and Biomechanical Risk Factors with Medial and Lateral Patellofemoral Joint Structural Damage On MRI: The Multicenter Osteoarthritis Study

    Joshua J. Stefanik1, Ke Wang2, K. Douglas Gross3, Frank Roemer4, John A. Lynch5, Neil Segal6, Cora E. Lewis7, Michael C. Nevitt8, Ali Guermazi9 and David T. Felson10, 1Clinical Epidemiology, Boston University, Boston, MA, 2Biostatistics, Boston University, Boston, MA, 3Physical Therapy, MGH Institute of Health Professions, Boston, MA, 4Klinikum Augsburg, Augsburg, Germany, 5Department of Epidemiology and Biostatistics, University of California at San Francisco, San Francisco, CA, 6Orthopaedics and Rehabilitation, University of Iowa, Iowa City, IA, 7Preventive Medicine, University of Alabama, Birmingham City, Birmingham, AL, 8Epidemiology & Biostatistics, UCSF (University of California, San Francisco), San Francisco, CA, 9Radiology, Boston University, Boston, MA, 10Boston University, Boston, MA

    Background/Purpose: Past investigations into risk factors for patellofemoral joint (PFJ) osteoarthritis (OA) have been limited by the use of radiography, which is insensitive to identify…
  • Abstract Number: 251 • 2012 ACR/ARHP Annual Meeting

    Smaller Baseline and Follow-up Quadriceps Muscle Cross-Sectional Area Increases the Odds of Knee Replacement in Knee Osteoarthritis

    Serter Gumus1, Michael J. Hannon2, Diana Kaya1, C. Kent Kwoh3 and Kyongtae Ty Bae1, 1Radiology, University of Pittsburgh, Pittsburgh, PA, 2Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, 3School of Medicine, Department of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA

    Background/Purpose: Knee osteoarthritis (OA) is one of the major causes of disability among elderly. Knee replacement (KR) is the final effective treatment of OA after…
  • Abstract Number: 2471 • 2012 ACR/ARHP Annual Meeting

    Oral Glucosamine Sulphate for the Prevention of Knee Osteoarthritis in Overweight Females; The First Ever Preventive Randomized Controlled Trial

    Jos Runhaar1, Marienke van Middelkoop1, Max Reijman2, Edwin Oei3, Dammis Vroegindeweij4, Gerjo van Osch2, Bart Koes1 and Sita Bierma-Zeinstra5, 1General Practice, Erasmus MC, Rotterdam, Netherlands, 2Orthopaedics, Erasmus MC, Rotterdam, Netherlands, 3Radiology, Erasmus MC, Rotterdam, Netherlands, 4Radiology, Maasstad Hospital, Rotterdam, Netherlands, 5Orthopaedics and General Practice, Erasmus MC, Rotterdam, Netherlands

    Background/Purpose: Previous studies showed the largest effects of glucosamine on osteoarthritis (OA) symptoms of the knee joint and when used in an early phase of…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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