Abstracts tagged "Osteoarthritis"

Abstract Number: 2179 • 2016 ACR/ARHP Annual Meeting
What Are the Risk Factors for Knee Pain, Radiographic Knee Osteoarthritis and Total Knee Replacement in Professional Footballers?
Sanjay M Parekh^1,2, Gwen S Fernandes^1,2,3, Jonathan P Moses^1,2, Colin Fuller⁴, Brigitte Scammell^1,2,3, Mark Batt^1,2,3, Weiya Zhang^1,2,3 and Michael Doherty^1,2,3, ¹Division of Rheumatology, Orthopaedics and Dermatology, School of Medicine, University of Nottingham, Nottingham, United Kingdom, ²Arthritis Research UK Centre for Sports, Exercise and Osteoarthritis, Nottingham, United Kingdom, ³Arthritis Research UK Pain Centre, Nottingham, United Kingdom, ⁴Colin Fuller Consultancy Ltd, Nottingham, United Kingdom
Background/Purpose: Football is the world’s most popular team sport. However, whether professional footballers have a higher prevalence of knee injury and subsequently, knee pain (KP),…
Abstract Number: 116 • 2016 ACR/ARHP Annual Meeting
Racial Differences in Self-Reported Pain and Disability: A Longitudinal Study of Knee Osteoarthritis
Ernest Vina¹, Di Ran², Erin Ashbeck² and C. Kent Kwoh³, ¹Rheumatology, University of Arizona, Tucson, AZ, ²University of Arizona, Tucson, AZ, ³Rheumatology, University of Arizona, College of Medicine, Tucson, AZ
Background/Purpose: Pain and disability from knee osteoarthritis (KOA) has been reported to be greater among African-Americans (AAs) than Whites (WHs), though progression in KOA-related…
Abstract Number: 2183 • 2016 ACR/ARHP Annual Meeting
The Electronic Osteoarthritis Knee and Hip Quality of Life (OAKHQOL) Questionnaire: A Useful and Valid Alternative to Measure Health-Related Quality of Life in Knee Osteoarthritis
Maud Wieczorek¹, Christine Rotonda^2,3, Francis Guillemin^4,5 and Anne-Christine Rat^4,5,6, ¹Apemac EA4360, Nancy, University of Lorraine, Vandoeuvre-lès Nancy, France, ²Apemac EA4360, Nancy, University of Lorraine, Vandoeuvre-lès-Nancy, France, ³CIC-1433 Epidémiologie Clinique, nancy, Inserm, Vandoeuvre-lès-Nancy, France, ⁴Apemac EA 4360, Nancy, University of Lorraine, Vandoeuvre-lès-Nancy, France, ⁵CIC-1433 Epidémiologie Clinique, Nancy, Inserm, Vandoeuvre-lès-Nancy, France, ⁶Rheumatology Department, CHRU Nancy, Vandoeuvre-lès-Nancy, France
Background/Purpose: With the growing development of new technologies in clinical research, an electronic version of the OsteoArthritis Knee and Hip Quality Of Life (OAKHQOL), the…
Abstract Number: 295 • 2016 ACR/ARHP Annual Meeting
Efficacy and Safety of Fasinumab for Osteoarthritic Pain in Patients with Moderate to Severe Osteoarthritis of the Knees or Hips
Jennifer Maloney¹, Alan Kivitz², Thomas J. Schnitzer³, Paula Dakin¹, Catherine Stehman-Breen¹ and Greg Geba¹, ¹Regeneron Pharmaceuticals, Inc., Tarrytown, NY, ²Altoona Center for Clinical Research, Duncansville, PA, ³Northwestern University, Chicago, IL
Background/Purpose: Osteoarthritis (OA) is an important cause of chronic pain in older adults. Fasinumab is a fully-human, high-affinity monoclonal antibody directed against the nerve growth…
Abstract Number: 2221 • 2016 ACR/ARHP Annual Meeting
Recognition of Secondary Fibromyalgia Using an Index of 3 Components of the Multi-Dimensional Health Assessment Questionnaire: 90% Agreement with ACR Criteria for Fibromyalgia
Kathryn Gibson^1,2, Isabel Castrejón³, Theodore Pincus³ and Katherine J. Bryant⁴, ¹Liverpool Hospital, Sydney, Sydney, Australia, ²Ingham Research Institute, Liverpool, Australia, ³Rheumatology, Rush University Medical Center, Chicago, IL, ⁴University of New South Wales, Sydney, Australia
Background/Purpose: Secondary fibromyalgia (FM) is seen 15-20% of patients with rheumatoid arthritis (RA) (1), systemic lupus erythematosus (SLE) (2), osteoarthritis (OA), and other rheumatic diseases.…
Abstract Number: 299 • 2016 ACR/ARHP Annual Meeting
Minimally Important Differences for Four Patient-Reported Outcomes Measurement Information System (PROMIS) Short Forms: Physical Function, Pain Interference, Depression, and Anxiety Among Adults with Knee Osteoarthritis
Augustine Lee¹, Lori Lyn Price², Jeffrey Driban³, William F. Harvey¹, Timothy E. McAlindon⁴, Angie Mae Rodday⁵ and Chenchen Wang¹, ¹Rheumatology, Tufts Medical Center, Boston, MA, ²Clinical Care Research, Tufts Medical Center, Boston, MA, ³Tufts Medical Center, Boston, MA, ⁴Division of Rheumatology, Tufts Medical Center, Boston, MA, ⁵Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA
Background/Purpose: Patient-Reported Outcomes Measurement Information System (PROMIS) provides reliable, valid measures of health status to resolve many challenges with comparability and interpretability in OA.…
Abstract Number: 2346 • 2016 ACR/ARHP Annual Meeting
The Improving Motivation for Physical Activity in Arthritis Clinical Trial for Adults with Knee Osteoarthritis and Rheumatoid Arthritis
Abigail Gilbert¹, Julia (Jungwha) Lee², Pamela Semanik³, Jing Song⁴, Christine Pellegrini⁵, Daniel Pinto⁶, Dorothy D. Dunlop⁴, Rowland W. Chang⁷ and Linda S. Ehrlich-Jones⁸, ¹Northwestern University Feinberg School of Medicine, Chicago, IL, ²Preventive Medicine/Biostatistics, Northwestern University Feinberg School of Medicine, Chicago, IL, ³College of Nursing, Rush University, Chicago, IL, ⁴Center for Healthcare Studies, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁵Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁶Department of Physical Therapy & Human Movement Sciences, Northwestern University, Chicago, IL, ⁷Institute for Public Health and Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁸Research CROR, Rehabilitation Institute Chicago, Chicago, IL
Abstract: Background/Purpose: Insufficiently active adults experience reduced quality of life. Because half of adults with arthritis are physically inactive, we evaluated the additional effect of…
Abstract Number: 303 • 2016 ACR/ARHP Annual Meeting
Knee Physical Exam Findings and Self-Reported Symptoms Are Associated with MRI-Detected Effusion-Synovitis Among Participants with or at Risk for Knee Osteoarthritis: Data from the Osteoarthritis Initiative (OAI)
Adam Berlinberg¹, Jordan Westra², Erin L. Ashbeck², Jaren Trost¹, Frank Roemer^3,4, Ali Guermazi⁵ and C. Kent Kwoh⁶, ¹Department of Medicine, University of Arizona, Tucson, AZ, ²The University of Arizona Arthritis Center, Tucson, AZ, ³Department of Radiology, Boston University School of Medicine, Boston, MA, ⁴Radiology, University of Erlangen, Erlangen, Germany, ⁵Boston University School of Medicine, Boston, MA, ⁶1501 N. Campbell Avenue, Room 8303, The University of Arizona Arthritis Center, Tucson, AZ
Background/Purpose: Inflammation has been implicated in the pathogenesis of KOA, but the relevance of physical exam findings and patient-reported symptoms of inflammation is unknown. Our…
Abstract Number: 2362 • 2016 ACR/ARHP Annual Meeting
Progression of Pain and Ultrasound Detected Synovitis in Patients with Erosive Hand Osteoarthritis over One Year
Olga Sleglova¹, Olga Ruzickova¹, Karel Pavelka¹ and Ladislav Senolt^1,2, ¹Institute of Rheumatology and Department of Rheumatology, 1st Faculty of Medicine, Charles University in Prague, Prague, Czech Republic, ²Institute of Rheumatology, Department of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic
Background/Purpose: Hand osteoarthritis (HOA) is a common and frequent cause of pain. HOA is a heterogeneous group of disorders with two main subsets including non-erosive…
Abstract Number: 316 • 2016 ACR/ARHP Annual Meeting
Postural Stability Is Associated with Lower Pain, Lower Stiffness, and Higher Muscle Power Among Adults with Symptomatic Knee Osteoarthritis
Wei Liu¹, Augustine C. Lee², William F. Harvey², Lori Lyn Price³, Jeffrey B. Driban² and Chenchen Wang², ¹Osteopathic Rehabilitation and Biomechanics, 1Edward Via College of Osteopathic Medicine, Auburn, AL, USA, Auburn, AL, ²Rheumatology, Tufts Medical Center, Boston, MA, ³Clinical Care Research, Tufts Medical Center, Boston, MA
Background/Purpose: Postural stability is an indicator of static standing balance and a critical component of physical function and fall prevention among those with knee OA.…
Abstract Number: 2363 • 2016 ACR/ARHP Annual Meeting
Synovial Changes Detected By Ultrasound and Its Association with Knee Pain: A Population-Based Case Control Study
Aliya Sarmanova^1,2, Michelle Hall³, Gwen Fernandes^2,4,5, Archan Bhattacharya^1,6, Ana Valdes^1,2,5, David Walsh^2,5,7, Michael Doherty^2,4,5 and Weiya Zhang^2,4,5, ¹Division of Rheumatology, Orthopaedics and Dermatology, School of Medicine, University of Nottingham, the UK, Nottingham, United Kingdom, ²Arthritis Research UK Pain Centre, Nottingham, United Kingdom, ³School of Health Sciences, University of Nottingham, the UK, Nottingham, United Kingdom, ⁴Division of Rheumatology, Orthopaedics and Dermatology, School of Medicine, University of Nottingham, Nottingham, United Kingdom, ⁵Arthritis Research UK Centre for Sports, Exercise and Osteoarthritis, Nottingham, United Kingdom, ⁶Arthritis Research UK Centre for Sports, Exercise and Osteoarthritis, Nottignham, United Kingdom, ⁷Division of Rheumatology, Orthopaedics and Dermatology, School of Medicine, University of Nottingham, the UK, Nottignham, United Kingdom
Background/Purpose: To examine whether synovial changes on ultrasound (US) associate with knee pain (KP) and/or underlying structural radiographic changes of osteoarthritis (OA).Methods: In this case-control…
Abstract Number: 320 • 2016 ACR/ARHP Annual Meeting
The Value of Adjusting for Physical Activity When Measuring Osteoarthritis-Related Pain
Kelli Allen¹, Katherine Hall², Jennifer H. Lindquist³, Shannon Taylor⁴ and Cynthia Coffman⁵, ¹University of North Carolina at Chapel Hill and Durham VA Medical Center, Chapel Hill, NC, ²Durham VA Medical Center and Duke University Medical Center, Durham, NC, ³Health Services Research, Durham VA Medical Center, Durham, NC, ⁴Durham VA Medical Center, Durham, NC, ⁵Health Services Research, Durham VA Medical Center and Duke University Medical Center, Durham, NC
Background/Purpose: Measures of chronic pain typically do not account for individuals’ physical activity (PA) levels. Although PA is essential for managing conditions like osteoarthritis (OA),…
Abstract Number: 2370 • 2016 ACR/ARHP Annual Meeting
Factors Affecting Interval Changes in Perceived Fatigue over Five Years in Patients with Rheumatoid Arthritis Compared with Osteoarthritis
Simon Stebbings^1,2, Gareth Treharne³, J. Haxby Abbott⁴ and Andrew Gray⁵, ¹Dunedin Hospital, Department of Rheumatology, Dunedin, New Zealand, ²Department of Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand, ³Psychology, University of Otago, Dunedin, New Zealand, ⁴Centre for Musculoskeletal Outcomes Research, Department of Surgical Sciences, University of Otago, Dunedin, New Zealand, ⁵Department of Preventive and Social Medicine, University of Otago, Dunedin, New Zealand
Background/Purpose: In a previous cross-sectional study we noted higher fatigue levels in patients with advanced lower limb OA compared with RA, and identified differences in…
Abstract Number: 57 • 2016 ACR/ARHP Annual Meeting
Genetic Polymorphism of IL-1RN Encoding the IL-1 Receptor Antagonist Predicts Radiographic Severity of Symptomatic Knee OA
Mukundan Attur¹, Sisi Ma², Jonathan Samuels³, Svetlana Krasnokutsky Samuels⁴, Hua Zhou², Jenny Bencardino⁵, Marc C. Hochberg⁶, Braxton Mitchell⁷, Virginia B. Kraus⁸, Joanne M. Jordan⁹ and Steven B. Abramson¹⁰, ¹Rheumatology Research, NYU - Hospital for Joint Diseases, New York, NY, ²Bioinformatics, New York University, New York, NY, ³Rheumatology, NYU - Hospital for Joint Diseases, New York, NY, ⁴Medicine/Rheumatology, NYU School of Medicine/NYU Hospital for Joint Diseases, New York, NY, ⁵Radiology, NYU Langone Medical Center, New York, NY, ⁶University of Maryland School of Medicine, Baltimore, MD, USA, Baltimore, MD, ⁷Departments of Medicine and Epidemiology & Public Health, University of Maryland School of Medicine, Baltimore, MD, ⁸Department of Medicine, Duke University Medical Center, Durham, NC, ⁹Thurston Arthritis Research Center, University of North CArolina at Chapel Hill, Chapel Hill, NC, ¹⁰Dept of Rheumatology/Medicine, Hosp for Joint Diseases/NYU, New York, NY
Background/Purpose: Growing numbers of studies show increased expression in Osteoarthritis (OA) of inflammatory cytokines, such as IL-1β and TNFα, in joint tissues and peripheral blood…
Abstract Number: 1093 • 2016 ACR/ARHP Annual Meeting
DNA Methylation Defines Joint Specific Differences in Synovial Fibroblasts from OA and RA Patients
Emmanuel Karouzakis¹, Mojca Frank Bertoncelj², Kerstin Klein¹, Christoph Kolling³, Renate E. Gay¹, Steffen Gay¹ and Caroline Ospelt¹, ¹Center of Experimental Rheumatology, University Hospital Zurich, Zurich, Switzerland, ²Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland, ³Schulthess Clinic, Zurich, Switzerland
Background/Purpose: Recent studies revealed epigenetic changes in DNA methylation associated with rheumatoid arthritis (RA) synovial fibroblasts (SF). In addition, we have shown that SF exhibit…

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