Abstracts tagged "Osteoarthritis"

Abstract Number: 1947 • 2017 ACR/ARHP Annual Meeting
Thy1 Is a Positive Regulator of Osteoblast Differentiation and Modulates Bone Homeostasis in Obese Mice
Ananta Paine¹, Collynn Woeller², Nelson Huertas¹, Maria de la Luz Garcia-Hernandez³, Richard Phipps² and Christopher T. Ritchlin⁴, ¹Department of Medicine, Division of Allergy, Immunology and Rheumatology, School of Medicine and Dentistry, University of Rochester, Rochester, New York, USA, Rochester, NY, ²Department of Environmental Medicine, School of Medicine and Dentistry,, Department of Environmental Medicine, School of Medicine and Dentistry, University of Rochester, Rochester, New York, USA, Rochester, NY, ³Department of Medicine,, Division of Allergy, Immunology and Rheumatology, School of Medicine and Dentistry, University of Rochester, Rochester, New York, USA, Rochester, NY, ⁴Division of Allergy, Immunology and Rheumatology, School of Medicine and Dentistry, Division of Allergy, Immunology and Rheumatology, School of Medicine and Dentistry, University of Rochester, Rochester, New York, USA, Rochester, NY
Background/Purpose: Thy1 (CD90) is a glycosylated, glycophosphatidylinositol (GPI)-anchored membrane protein originally identified as a marker for mouse T cells but subsequent reports noted expression on…
Abstract Number: 2428 • 2017 ACR/ARHP Annual Meeting
Epstein-Barr Virus Infection and Epstein-Barr Virus　Nuclear Antigen 1 Variants in the Synovial Tissue of Rheumatoid Arthritis
Shotaro Masuoka¹, Natsuko Kusunoki¹, Shinichi Kawai² and Toshihiro Nanki¹, ¹Division of Rheumatology, Department of Internal Medicine, Toho University School of Medicine, Tokyo, Japan, ²Department of Inflammation and Pain Control Research, Toho University School of Medicine, Tokyo, Japan
Background/Purpose: Epstein-Barr virus (EBV) infection causes various malignant tumors such as B cell lymphoma and epithelial cell cancer. Previous reports showed several variants in carboxyl-terminal…
Abstract Number: 2179 • 2017 ACR/ARHP Annual Meeting
Comparing Observed with Expected Assessments of Osteoarthritic Pain over Time: Application of Successive Prediction to Data from the Osteoarthritis Initiative
Steven Mongin¹, Naoko Onizuka², Lisa Langsetmo³ and Anna Shmagel⁴, ¹Biostatistics, University of Minnesota School of Public Health, Minneapolis, MN, ²Medicine, University of Minnesota, Minneapolis, MN, ³University of Minnesota School of Public Health, Minneapolis, MN, ⁴Rheumatic & Autoimmune Diseases, University of Minnesota, Minneapolis, MN
Background/Purpose: High variability in patient-reported outcome scores presents a major challenge in the design and interpretation of clinical studies in osteoarthritis (OA). We present a…
Abstract Number: 2766 • 2017 ACR/ARHP Annual Meeting
Physical Therapy Vs. Internet-Based Exercise Training for Patients with Knee Osteoarthritis: Results of a Randomized Controlled Trial
Kelli Allen¹, Liubov Arbeeva², Leigh F. Callahan³, Yvonne M. Golightly⁴, Adam P. Goode⁵, Bryan Heiderscheit⁶, Carla Hill⁷, Kim Huffman⁸, Herbert Seversen⁹ and Todd A. Schwartz¹⁰, ¹Rheumatology, University of North Carolina at Chapel Hill and Durham VA Medical Center, Durham, NC, ²Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, ³Thurston Arthritis Research Center, University of North Carolina, Chapel Hill, NC, ⁴Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, ⁵O, Duke University, Durham, NC, ⁶Department of Orthopedics and Rehabilitation, University of Wisconsin, Madison, WI, ⁷University of North Carolina at Chapel Hill, Chapel Hill, NC, ⁸School of Medicine, Division of Rheumatology, Immunology and Molecular Physiology and Durham VA Medical Center, Duke University, Durham, NC, ⁹Oregon Research Institute, Durham, OR, ¹⁰Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC
Background/Purpose: The majority of adults with osteoarthritis (OA) are inactive, highlighting the need for continued efforts to promote regular engagement in exercise. Few studies have…
Abstract Number: 217 • 2017 ACR/ARHP Annual Meeting
Keeping a Balance: Social Engagement and Care Giving
Elizabeth M. Badley^1,2, Dov Millstone² and Anthony V. Perruccio^2,3,4, ¹Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada, ²Health Care & Outcomes Research, Krembil Research Institute, University Health Network, Toronto, ON, Canada, ³Arthritis Program, Krembil Research Institute, University Health Network, Toronto, ON, Canada, ⁴Institute of Health Policy, Management & Evaluation, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada
Background/Purpose: Arthritis is associated with pain and disability. As a result there has been some interest in examining the receipt of care among those with…
Abstract Number: 2181 • 2017 ACR/ARHP Annual Meeting
Is a Decrease in MRI-Defined Inflammation Associated with a Decrease in Pain in Patients with Hand Osteoarthritis? a Two-Year Follow-up Study
S. van Beest¹, W. Damman¹, R. Liu¹ and M. Kloppenburg², ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Rheumatology and Clinical Epidemiology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: Joint pain in hand osteoarthritis (OA) is associated with synovitis in cross-sectional studies. Therefore we hypothesized that synovitis could be a target for treatment.…
Abstract Number: 2849 • 2017 ACR/ARHP Annual Meeting
Pain and Functional Trajectories in Symptomatic Knee Osteoarthritis over a 12-Week Period of Non-Pharmacological Exercise Interventions
Augustine Lee¹, William F. Harvey², Xingyi Han¹, Lori Lyn Price^3,4, Jeffrey B. Driban¹, Raveendhara R. Bannuru¹ and Chenchen Wang², ¹Rheumatology, Tufts Medical Center, Boston, MA, ²Rheumatology, Center of Integrative Medicine and Division of Rheumatology, Tufts Medical Center, Boston, MA, Boston, MA, ³Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, ⁴Tufts Clinical and Translational Science Institute, Tufts University, Boston, MA
Background/Purpose: Exercise is the recommended treatment for knee osteoarthritis (OA). However, heterogeneous patterns in treatment response are poorly understood. Our purpose was to identify pain…
Abstract Number: 1254 • 2016 ACR/ARHP Annual Meeting
Knee Pain and Patient Preference for Knee Replacement: Healthcare Access Matters
Manjinder Kaur¹, Erin Ashbeck², Di Ran², C. Kent Kwoh³ and Ernest Vina⁴, ¹Internal Medicine, University of Arizona, Tucson, AZ, ²University of Arizona, Tucson, AZ, ³Rheumatology, University of Arizona, College of Medicine, Tucson, AZ, ⁴Rheumatology, University of Arizona, Tucson, AZ
Background/Purpose: Total knee replacement (TKR) is a cost-effective intervention for end-stage knee osteoarthritis (OA). Objectives were to estimate the effect of knee pain severity on…
Abstract Number: 1431 • 2016 ACR/ARHP Annual Meeting
Estimates of Global Status By Physicians and Patients Are More Likely to be Discordant in Osteoarthritis Than in Rheumatoid Arthritis
Isabel Castrejón¹, Joel Block² and Theodore Pincus¹, ¹Rheumatology, Rush University Medical Center, Chicago, IL, ²Division of Rheumatology, Rush University Medical Center, Chicago, IL
Background/Purpose: Concordant 0-10 estimates of global status by physicians (DOCGL) and patients (PATGL) are associated with greater expectations for improvement and better outcomes1, and appear…
Abstract Number: 1522 • 2016 ACR/ARHP Annual Meeting
Disease Burden in Rheumatoid Arthritis (RA) Patients Who Have Secondary Osteoarthritis (OA) Is Lower Than in OA but Higher Than in RA with No Secondary OA
Isabel Castrejón¹, Anne-Marie Malfait², Joel Block³ and Theodore Pincus¹, ¹Rheumatology, Rush University Medical Center, Chicago, IL, ²Biochemistry & Rheumatology, Rush University Medical Center, Chicago, IL, ³Division of Rheumatology, Rush University Medical Center, Chicago, IL
Background/Purpose: Recent data indicate that the disease burden experienced by patients with osteoarthritis (OA) is similar to or greater than in rheumatoid arthritis (RA) (EULAR…
Abstract Number: 2031 • 2016 ACR/ARHP Annual Meeting
Dietary Patterns and Radiographic Progression of Knee Osteoarthritis: Data from the Osteoarthritis Initiative
Bing Lu¹, Jeffrey Driban², Chang Xu³, Timothy E. McAlindon⁴ and Charles B. Eaton⁵, ¹Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ²Tufts Medical Center, Boston, MA, ³Statistics, Rutgers University, New Brunswick, NJ, ⁴Division of Rheumatology, Tufts Medical Center, Boston, MA, ⁵Family Medicine and Community Health( Epidemiology), Alpert Medical School of Brown University, Pawtucket, RI
Background/Purpose: Although some individual foods and nutrients have been associated with knee osteoarthritis (OA) progression, the association between overall diet and OA progression is unknown.…
Abstract Number: 2133 • 2016 ACR/ARHP Annual Meeting
Simulation of Cartilage Damage in Osteoarthritis Using Patient-Derived Induced Pluripotent Stem Cells
Seung Min Jung¹, Yoojun Nam², Yeri Alice Rim², Yong-Beom Park¹, Seung-Ki Kwok³, Sung-Hwan Park⁴ and Ji Hyeon Ju⁵, ¹Division of Rheumatology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, South Korea, ²Division of Rheumatology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea, The Republic of, ³[email protected], Division of Rheumatology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, South Korea, ⁴Division of Rheumatology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, South Korea, ⁵Division of Rheumatology, Department of Internal Medicine,, College of Medicine, The Catholic University of Korea, Seoul, South Korea
Background/Purpose: Osteoarthritis (OA) is a degenerative joint disease, leading to pain and functional limitation. Although OA is a most common form of musculoskeletal disease, the…
Abstract Number: 2179 • 2016 ACR/ARHP Annual Meeting
What Are the Risk Factors for Knee Pain, Radiographic Knee Osteoarthritis and Total Knee Replacement in Professional Footballers?
Sanjay M Parekh^1,2, Gwen S Fernandes^1,2,3, Jonathan P Moses^1,2, Colin Fuller⁴, Brigitte Scammell^1,2,3, Mark Batt^1,2,3, Weiya Zhang^1,2,3 and Michael Doherty^1,2,3, ¹Division of Rheumatology, Orthopaedics and Dermatology, School of Medicine, University of Nottingham, Nottingham, United Kingdom, ²Arthritis Research UK Centre for Sports, Exercise and Osteoarthritis, Nottingham, United Kingdom, ³Arthritis Research UK Pain Centre, Nottingham, United Kingdom, ⁴Colin Fuller Consultancy Ltd, Nottingham, United Kingdom
Background/Purpose: Football is the world’s most popular team sport. However, whether professional footballers have a higher prevalence of knee injury and subsequently, knee pain (KP),…
Abstract Number: 116 • 2016 ACR/ARHP Annual Meeting
Racial Differences in Self-Reported Pain and Disability: A Longitudinal Study of Knee Osteoarthritis
Ernest Vina¹, Di Ran², Erin Ashbeck² and C. Kent Kwoh³, ¹Rheumatology, University of Arizona, Tucson, AZ, ²University of Arizona, Tucson, AZ, ³Rheumatology, University of Arizona, College of Medicine, Tucson, AZ
Background/Purpose: Pain and disability from knee osteoarthritis (KOA) has been reported to be greater among African-Americans (AAs) than Whites (WHs), though progression in KOA-related…
Abstract Number: 2183 • 2016 ACR/ARHP Annual Meeting
The Electronic Osteoarthritis Knee and Hip Quality of Life (OAKHQOL) Questionnaire: A Useful and Valid Alternative to Measure Health-Related Quality of Life in Knee Osteoarthritis
Maud Wieczorek¹, Christine Rotonda^2,3, Francis Guillemin^4,5 and Anne-Christine Rat^4,5,6, ¹Apemac EA4360, Nancy, University of Lorraine, Vandoeuvre-lès Nancy, France, ²Apemac EA4360, Nancy, University of Lorraine, Vandoeuvre-lès-Nancy, France, ³CIC-1433 Epidémiologie Clinique, nancy, Inserm, Vandoeuvre-lès-Nancy, France, ⁴Apemac EA 4360, Nancy, University of Lorraine, Vandoeuvre-lès-Nancy, France, ⁵CIC-1433 Epidémiologie Clinique, Nancy, Inserm, Vandoeuvre-lès-Nancy, France, ⁶Rheumatology Department, CHRU Nancy, Vandoeuvre-lès-Nancy, France
Background/Purpose: With the growing development of new technologies in clinical research, an electronic version of the OsteoArthritis Knee and Hip Quality Of Life (OAKHQOL), the…

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