Abstracts tagged "Osteoarthritis"

Abstract Number: 2944 • 2017 ACR/ARHP Annual Meeting
Patterns and Characteristics of Accelerated Hand Osteoarthritis: Data from the Osteoarthritis Initiative
Julie Davis¹, Lena Franziska Schaefer², Timothy E. McAlindon³, Charles B. Eaton⁴, Mary Roberts⁵, Ida K. Haugen⁶, Stacy Smith⁷, Jeffrey Duryea², Bing Lu⁸ and Jeffrey B. Driban¹, ¹Rheumatology, Tufts Medical Center, Boston, MA, ²Radiology, Brigham & Women's Hospital/ Harvard Medical School, Boston, MA, ³Division of Rheumatology, Tufts Medical Center, Boston, MA, ⁴Family Medicine and Community Health( Epidemiology), Alpert Medical School of Brown University, Pawtucket, RI, ⁵Center for Primary Care and Prevention, Memorial Hospital of Rhode Island, Pawtucket, RI, ⁶Diakonhjemmet Hospital, Oslo, Norway, ⁷Radiology/Division of Musculoskeletal Imaging & Intervention, Brigham & Women's Hospital/ Harvard Medical School, Boston, MA, ⁸Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA
Background/Purpose: Epidemiology for hand osteoarthritis (OA) incidence is lacking and few large cohorts have sufficient size to explore subsets. We previously characterized a subset of…
Abstract Number: 859 • 2017 ACR/ARHP Annual Meeting
Identifying Pain Susceptibility Phenotypes in Those Free of Knee Pain with or at Risk for Knee Osteoarthritis and Their Relation to Developing Knee Pain
Lisa Carlesso¹, Neil Segal², Laura Frey-Law³, Yuqing Zhang⁴, Na Lu⁵, Cora E. Lewis⁶, Michael C. Nevitt⁷ and Tuhina Neogi⁵, ¹School of Rehabilitation, Université de Montréal, Montreal, QC, Canada, ²University of Kansas, Shawnee, KS, ³UIowa, Iowa City, IA, ⁴Clinical Edpidemiology Reserach and Training Unit, Boston University School of Medicine, Boston, MA, ⁵Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ⁶University of Alabama Birmingham, Birmingham, AL, ⁷Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA
Background/Purpose: It is well recognized that factors beyond structural features contribute to the pain experience in people with knee osteoarthritis (OA). Independent of structural pathology,…
Abstract Number: 2199 • 2017 ACR/ARHP Annual Meeting
Feasibility of a Novel Approach to Studying Early Knee Osteoarthritis: An Offspring Study
Grace H. Lo¹, Jane A. Cauley², Michael T. Strayhorn³, Mary Jansen⁴, Michael J Hannon⁵, Donna White⁶, Stephanie Green⁷ and C. Kent Kwoh^8,9, ¹Immunology, Allergy, Rheumatology, Baylor College of Medicine, Houston, TX, ²Department of Epidemiology, Univ of Pittsburgh, Pittsburgh, PA, ³VA HSR&D Center for Innovations in Quality, Effectiveness and Safety; Department of Medicine, Michael E. DeBakey VA Medical Center, Baylor College of Medicine, Houston, TX, ⁴University of Pittsburgh, Pittsburgh, PA, ⁵Medicine, University of Pittsburgh, Pittsburgh, PA, ⁶Baylor College of Medicine, Houston, TX, ⁷Univeristy of Pittsburgh, Houston, PA, ⁸University of Arizona, Tucson, AZ, ⁹1501 N. Campbell Avenue, Room 8303, The University of Arizona Arthritis Center, Tucson, AZ
Background/Purpose: Much of osteoarthritis (OA) research has focused on identifying treatments for late stage disease. However, interventions in early disease may be most effective. Capitalizing…
Abstract Number: 2946 • 2017 ACR/ARHP Annual Meeting
Identifying Rapid Structural Disease Progression in Knee Osteoarthritis
Jamie E. Collins^1,2, Jeffrey N. Katz^2,3 and Elena Losina^1,2, ¹Orthopaedic and Arthritis Center for Outcomes Research, Department of Orthopedic Surgery, Brigham & Women's Hospital, Boston, MA, ²Harvard Medical School, Boston, MA, ³Rheumatology, Immunology, and Allergy, Brigham & Women's Hospital, Boston, MA
Background/Purpose: Knee OA is a heterogeneous disease, with some patients experiencing rapid deterioration and others experiencing slow disease progression. Identifying patients likely to experience rapid…
Abstract Number: 931 • 2017 ACR/ARHP Annual Meeting
Dose-Response Effects of Tai Chi and Physical Therapy Exercise Interventions in Symptomatic Knee Osteoarthritis
Augustine Lee¹, William F. Harvey², Lori Lyn Price^3,4, Xingyi Han¹, Jeffrey B. Driban¹, Maura D. Iversen^5,6, Raveendhara R. Bannuru¹ and Chenchen Wang², ¹Rheumatology, Tufts Medical Center, Boston, MA, ²Rheumatology, Center of Integrative Medicine and Division of Rheumatology, Tufts Medical Center, Boston, MA, Boston, MA, ³Tufts Clinical and Translational Science Institute, Tufts University, Boston, MA, ⁴Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, ⁵Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ⁶Department of Physical Therapy, Movement & Rehabilitation Sciences, Northeastern University, Boston, MA
Background/Purpose: Therapeutic exercise is the recommended non-pharmacological treatment for knee osteoarthritis (OA). However, the optimal treatment dose and clinically meaningful treatment durations remain unclear. Our…
Abstract Number: 2203 • 2017 ACR/ARHP Annual Meeting
Association of Hip Bone Geometry and Volumetric Density with Hip Osteoarthritis
Johann Grapinet¹, Jean-Baptiste Pialat¹, mathilde Proriol¹, Pawel Szulc², Eric Lespessailles³ and Roland Chapurlat⁴, ¹INSERM UMR 1033, LYON, France, ²Epidemiology of Osteoporosis, INSERM UMR 1033, Lyon, France, ³University Orleans, Orleans, France, ⁴INSERM 1033, University of Lyon, E. Herriot Hospital, Hospices Civils de Lyon, Lyon, France
Background/Purpose: Hip osteoarthritis (OA) is a major public health concern. It is associated with hip pain, functional decline and possibly increased cardiovascular mortality. The determinants…
Abstract Number: 2948 • 2017 ACR/ARHP Annual Meeting
Distinct Trajectories of Medial Fixed Joint Space Width Loss over Four Years of Follow-up Among Knees with and at Risk for Knee Osteoarthritis
C. Kent Kwoh^1,2, Di Ran^2,3, Erin L. Ashbeck² and Jeffrey Duryea⁴, ¹Division of Rheumatology, Department of Medicine, The University of Arizona, Tucson, AZ, ²The University of Arizona Arthritis Center, Tucson, AZ, ³Department of Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health, Tucson, AZ, ⁴Radiology, Brigham & Women's Hospital/ Harvard Medical School, Boston, MA
Background/Purpose: Knee OA (KOA) is typically described as a slowly progressive disease, though it is recognized that some patients experience rapid structural deterioration. Identification of…
Abstract Number: 2133 • 2016 ACR/ARHP Annual Meeting
Simulation of Cartilage Damage in Osteoarthritis Using Patient-Derived Induced Pluripotent Stem Cells
Seung Min Jung¹, Yoojun Nam², Yeri Alice Rim², Yong-Beom Park¹, Seung-Ki Kwok³, Sung-Hwan Park⁴ and Ji Hyeon Ju⁵, ¹Division of Rheumatology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, South Korea, ²Division of Rheumatology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea, The Republic of, ³[email protected], Division of Rheumatology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, South Korea, ⁴Division of Rheumatology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, South Korea, ⁵Division of Rheumatology, Department of Internal Medicine,, College of Medicine, The Catholic University of Korea, Seoul, South Korea
Background/Purpose: Osteoarthritis (OA) is a degenerative joint disease, leading to pain and functional limitation. Although OA is a most common form of musculoskeletal disease, the…
Abstract Number: 2179 • 2016 ACR/ARHP Annual Meeting
What Are the Risk Factors for Knee Pain, Radiographic Knee Osteoarthritis and Total Knee Replacement in Professional Footballers?
Sanjay M Parekh^1,2, Gwen S Fernandes^1,2,3, Jonathan P Moses^1,2, Colin Fuller⁴, Brigitte Scammell^1,2,3, Mark Batt^1,2,3, Weiya Zhang^1,2,3 and Michael Doherty^1,2,3, ¹Division of Rheumatology, Orthopaedics and Dermatology, School of Medicine, University of Nottingham, Nottingham, United Kingdom, ²Arthritis Research UK Centre for Sports, Exercise and Osteoarthritis, Nottingham, United Kingdom, ³Arthritis Research UK Pain Centre, Nottingham, United Kingdom, ⁴Colin Fuller Consultancy Ltd, Nottingham, United Kingdom
Background/Purpose: Football is the world’s most popular team sport. However, whether professional footballers have a higher prevalence of knee injury and subsequently, knee pain (KP),…
Abstract Number: 116 • 2016 ACR/ARHP Annual Meeting
Racial Differences in Self-Reported Pain and Disability: A Longitudinal Study of Knee Osteoarthritis
Ernest Vina¹, Di Ran², Erin Ashbeck² and C. Kent Kwoh³, ¹Rheumatology, University of Arizona, Tucson, AZ, ²University of Arizona, Tucson, AZ, ³Rheumatology, University of Arizona, College of Medicine, Tucson, AZ
Background/Purpose: Pain and disability from knee osteoarthritis (KOA) has been reported to be greater among African-Americans (AAs) than Whites (WHs), though progression in KOA-related…
Abstract Number: 2183 • 2016 ACR/ARHP Annual Meeting
The Electronic Osteoarthritis Knee and Hip Quality of Life (OAKHQOL) Questionnaire: A Useful and Valid Alternative to Measure Health-Related Quality of Life in Knee Osteoarthritis
Maud Wieczorek¹, Christine Rotonda^2,3, Francis Guillemin^4,5 and Anne-Christine Rat^4,5,6, ¹Apemac EA4360, Nancy, University of Lorraine, Vandoeuvre-lès Nancy, France, ²Apemac EA4360, Nancy, University of Lorraine, Vandoeuvre-lès-Nancy, France, ³CIC-1433 Epidémiologie Clinique, nancy, Inserm, Vandoeuvre-lès-Nancy, France, ⁴Apemac EA 4360, Nancy, University of Lorraine, Vandoeuvre-lès-Nancy, France, ⁵CIC-1433 Epidémiologie Clinique, Nancy, Inserm, Vandoeuvre-lès-Nancy, France, ⁶Rheumatology Department, CHRU Nancy, Vandoeuvre-lès-Nancy, France
Background/Purpose: With the growing development of new technologies in clinical research, an electronic version of the OsteoArthritis Knee and Hip Quality Of Life (OAKHQOL), the…
Abstract Number: 295 • 2016 ACR/ARHP Annual Meeting
Efficacy and Safety of Fasinumab for Osteoarthritic Pain in Patients with Moderate to Severe Osteoarthritis of the Knees or Hips
Jennifer Maloney¹, Alan Kivitz², Thomas J. Schnitzer³, Paula Dakin¹, Catherine Stehman-Breen¹ and Greg Geba¹, ¹Regeneron Pharmaceuticals, Inc., Tarrytown, NY, ²Altoona Center for Clinical Research, Duncansville, PA, ³Northwestern University, Chicago, IL
Background/Purpose: Osteoarthritis (OA) is an important cause of chronic pain in older adults. Fasinumab is a fully-human, high-affinity monoclonal antibody directed against the nerve growth…
Abstract Number: 2221 • 2016 ACR/ARHP Annual Meeting
Recognition of Secondary Fibromyalgia Using an Index of 3 Components of the Multi-Dimensional Health Assessment Questionnaire: 90% Agreement with ACR Criteria for Fibromyalgia
Kathryn Gibson^1,2, Isabel Castrejón³, Theodore Pincus³ and Katherine J. Bryant⁴, ¹Liverpool Hospital, Sydney, Sydney, Australia, ²Ingham Research Institute, Liverpool, Australia, ³Rheumatology, Rush University Medical Center, Chicago, IL, ⁴University of New South Wales, Sydney, Australia
Background/Purpose: Secondary fibromyalgia (FM) is seen 15-20% of patients with rheumatoid arthritis (RA) (1), systemic lupus erythematosus (SLE) (2), osteoarthritis (OA), and other rheumatic diseases.…
Abstract Number: 299 • 2016 ACR/ARHP Annual Meeting
Minimally Important Differences for Four Patient-Reported Outcomes Measurement Information System (PROMIS) Short Forms: Physical Function, Pain Interference, Depression, and Anxiety Among Adults with Knee Osteoarthritis
Augustine Lee¹, Lori Lyn Price², Jeffrey Driban³, William F. Harvey¹, Timothy E. McAlindon⁴, Angie Mae Rodday⁵ and Chenchen Wang¹, ¹Rheumatology, Tufts Medical Center, Boston, MA, ²Clinical Care Research, Tufts Medical Center, Boston, MA, ³Tufts Medical Center, Boston, MA, ⁴Division of Rheumatology, Tufts Medical Center, Boston, MA, ⁵Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA
Background/Purpose: Patient-Reported Outcomes Measurement Information System (PROMIS) provides reliable, valid measures of health status to resolve many challenges with comparability and interpretability in OA.…
Abstract Number: 2346 • 2016 ACR/ARHP Annual Meeting
The Improving Motivation for Physical Activity in Arthritis Clinical Trial for Adults with Knee Osteoarthritis and Rheumatoid Arthritis
Abigail Gilbert¹, Julia (Jungwha) Lee², Pamela Semanik³, Jing Song⁴, Christine Pellegrini⁵, Daniel Pinto⁶, Dorothy D. Dunlop⁴, Rowland W. Chang⁷ and Linda S. Ehrlich-Jones⁸, ¹Northwestern University Feinberg School of Medicine, Chicago, IL, ²Preventive Medicine/Biostatistics, Northwestern University Feinberg School of Medicine, Chicago, IL, ³College of Nursing, Rush University, Chicago, IL, ⁴Center for Healthcare Studies, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁵Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁶Department of Physical Therapy & Human Movement Sciences, Northwestern University, Chicago, IL, ⁷Institute for Public Health and Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁸Research CROR, Rehabilitation Institute Chicago, Chicago, IL
Abstract: Background/Purpose: Insufficiently active adults experience reduced quality of life. Because half of adults with arthritis are physically inactive, we evaluated the additional effect of…

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