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Abstracts tagged "Osteoarthritis"

  • Abstract Number: 1350 • ACR Convergence 2022

    A Prospective Study on Pain Associated with Injection of Needles: PAIN Study

    Chay Bae1, Eugenia Chen1 and Maida Wong2, 1Rheumatology, University of California, Irvine School of Medicine, Irvine, CA, 2Rheumatology, VA Long Beach Healthcare System, Long Beach, CA

    Background/Purpose: Joint pain is a common issue amongst patients. In the appropriate clinical setting, joint injections or aspirations may benefit the patient. Pain, however, is…
  • Abstract Number: 1786 • ACR Convergence 2022

    Anterior Knee Pain Is Associated with 2-year Compartment Specific Patellofemoral Cartilage Worsening: The MOST Study

    Corey Lanois1, Natalie Collins2, Tuhina Neogi3, Ali Guermazi4, Frank Roemer5, Michael LaValley6, Michael Nevitt7, James Torner8, Cora E. Lewis9 and Joshua Stefanik10, 1Northeastern University, Providence, RI, 2University of Queensland, Brisbane, Australia, 3Boston University School of Medicine, Boston, MA, 4Boston University, Boston, MA, 5Friedrich-Alexander University Erlangen Nürnberg, Erlangen, Germany, 6Boston University School of Public Health, Arlington, MA, 7University of California at San Francisco, Orinda, CA, 8University of Iowa, Iowa City, IA, 9University of Alabama at Birmingham, Birmingham, AL, 10Northeastern University, Boston, MA

    Background/Purpose: Anterior knee pain (AKP) may be a precursor to patellofemoral osteoarthritis (PFOA). Cross-sectionally, frequent AKP has been associated with MRI features of PFOA; however,…
  • Abstract Number: 1903 • ACR Convergence 2022

    Does Pain Sensitization by Pressure Pain Thresholds and Temporal Summation Predict Persistent Pain in Persons with Hand OA?

    Pernille Steen Pettersen1, Tuhina Neogi2, Elisabeth Mulrooney1, Marthe Gløersen1, Hilde Berner Hammer3 and Ida K. Haugen1, 1Center for treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway, Oslo, Norway, 2Boston University School of Medicine, Boston, MA, 3Diakonhjemmet hospital, Jar, Norway

    Background/Purpose: Pain sensitization is part of the complexity of osteoarthritis (OA) pain. We aimed to examine whether pain sensitization by pressure pain thresholds (PPT) and…
  • Abstract Number: 1919 • ACR Convergence 2022

    Underdiagnosis and Undertreatment of Knee Osteoarthritis in Persons with Type 2 Diabetes: A Cross-sectional Study

    Lauren King1, Esther Waugh1, Ian Stanaitis2, Alanna Weisman1, Baiju Shah1, Lorraine Lipscombe1 and Gillian Hawker1, 1University of Toronto, Toronto, ON, Canada, 2Women's College Hospital, Toronto, ON, Canada

    Background/Purpose: Knee osteoarthritis (OA) and type 2 diabetes commonly co-occur due to shared risk factors. Concomitant knee OA makes type 2 diabetes management, particularly engaging…
  • Abstract Number: 0101 • ACR Convergence 2022

    Twenty-five Years of Mortality Data in Those with Lower Extremity Osteoarthritis: The Role of Socioeconomic Status

    Cara Murphy1, Rebecca Cleveland1, Amanda Nelson2, Yvonne Golightly3 and Leigh Callahan4, 1University of North Carolina, Chapel Hill, NC, 2University of North Carolina at Chapel Hill, Chapel Hill, NC, 3University of Nebraska Medical Center, Omaha, NE, 4University of North Carolina Thurston Arthritis Research Center, Chapel Hill, NC

    Background/Purpose: The purpose of this study is to explore the relationship between socioeconomic status (SES) measures (income, professional employment, block group poverty level, education level,…
  • Abstract Number: 0841 • ACR Convergence 2022

    Relation of PainDETECT to Unpredictable Pain in People with or at Risk of Knee Osteoarthritis

    Kosaku Aoyagi1, Laura Frey-Law2, Gabriela Rabasa3, Cora E. Lewis4, Michael Nevitt5 and Tuhina Neogi6, 1Boston University, Quincy, MA, 2University of Iowa, Iowa City, IA, 3Boston University, Boston, MA, 4University of Alabama at Birmingham, Birmingham, AL, 5University of California at San Francisco, Orinda, CA, 6Boston University School of Medicine, Boston, MA

    Background/Purpose: PainDETECT has been used in studies of knee OA to identify "neuropathic-like pain", though neuropathic lesions have not been identified in clinical knee OA.…
  • Abstract Number: 1353 • ACR Convergence 2022

    Dietary Practices and Beliefs of Patients with Rheumatic Diseases and Relationship with Symptoms: Results of a Multicenter Cross-sectional Study

    Domitille RENARD1, Sophie Tuffet2, Philippe Dieude3, Pascal Claudepierre4, Laure Gossec5, Bruno Fautrel6, Anna Molto7, Corinne MIceli8, Pascal Richette9, Emmanuel Maheu10, Claire Carette11, Sebastien Czernichow11, Chloe JAMAKORZYAN12, alexandra Rousseau2, Francis Berenbaum13, Catherine Beauvais14 and Jérémie SELLAM15, 1Sorbonne University Paris- Sant Antoine Hospital, Paris, France, 2Saint Antoine hospital, Paris, Ile-de-France, France, 3Université Paris Cité, Paris, France, 4Paris Est Creteil University, Creteil, France, 5Sorbonne Université, Paris, France, 6Sorbonne University Paris, France and Pierre Louis Institute of Epidemiology and Public Health, Paris, France, Paris, France, 7Rheumatology Department, Cochin Hospital, APHP, Paris, France, 8APHP, Paris, France, 9Department of Rheumatology, Hôpital Lariboisière, Assistance Publique-Hôpitaux de Paris, Paris, France, 10Hôpital Paris Saint Antoine, Moirans, Auvergne-Rhône-Alpes, France, 11Hôpital Européen Georges Pompidou, Paris, France, 12Hopital Begin, Saint-Mandé, France, 13Sorbonne University - Saint-Antoine hospital, Paris, France, 14Saint Antoine hospital, Paris, France, 15Sorbonne Universite, AP-HP, Saint-Antoine hospital, Paris, France

    Background/Purpose: Diet is a subject of questioning and beliefs among patients with rheumatic diseases. They are inclined to change their eating habits and sometimes follow…
  • Abstract Number: 1888 • ACR Convergence 2022

    Novel Small Molecule Modulator of the gp130 Receptor Shows Dose-dependent Therapeutic Efficacy in a Canine Model of Osteoarthritis

    Ben Van Handel1, Candace Flynn2, Emma Lamoure2, Nancy Liu3, Jinxiu Lu3, Nancy Lane4, Mark Hurtig2 and Denis Evseenko3, 1CarthroniX, Inc., Los Angeles, CA, 2University of Guelph, Guelph, ON, Canada, 3University of Southern California, Los Angeles, CA, 4University of California Davis, Hillsborough, CA

    Background/Purpose: The pathogenesis of OA often begins from an injury to articular cartilage, which establishes chronic, low-grade inflammation principally mediated by IL-6 family cytokines that…
  • Abstract Number: 1904 • ACR Convergence 2022

    Is Treating Painful Hand Osteoarthritis with Hormone Replacement Therapy Feasible? Primary Results from a Randomised Controlled Trial in Post-menopausal Women

    Jennifer Williams1, Mae Chester-Jones1, Megan Goff2, Anne Francis1, Gretchen Brewer1, Ioana Marian1, Malvika Gulati1, Charles Mackworth-Young3, Victoria Glover4, Sarah Lamb1, Tonia Vincent5, Katy Vincent1, Susan Dutton1 and Fiona Watt6, 1University of Oxford, Oxford, United Kingdom, 2University of Oxford, London, United Kingdom, 3Imperial College Healthcare NHS Trust, London, United Kingdom, 4White Horse Medical Practice, Faringdon, United Kingdom, 5Kennedy Institute of Rheumatology, University of Oxford, Oxford, United Kingdom, 6Imperial College London, London, United Kingdom

    Background/Purpose: Hand osteoarthritis (OA) is more common in females and relative risk increases further around the age of menopause, potentially implicating sex hormone deficiency. There…
  • Abstract Number: 1920 • ACR Convergence 2022

    Gait and Physical Activity Predictors of Knee Replacement: A Machine Learning Analysis in the Multicenter Osteoarthritis Study

    Kerry Costello1, David Felson1, S. Reza Jafarzadeh2, Neil Segal3, Cora E. Lewis4, Michael Nevitt5, Vijaya Kolachalama2 and Deepak Kumar1, 1Boston University, Boston, MA, 2Boston University School of Medicine, Boston, MA, 3University of Kansas, Kansas City, KS, 4University of Alabama at Birmingham, Birmingham, AL, 5University of California at San Francisco, Orinda, CA

    Background/Purpose: Rates of knee replacement (KR) due to knee osteoarthritis (OA) are rising exponentially and currently no interventions prevent KR. Gait and physical activity are…
  • Abstract Number: 0122 • ACR Convergence 2022

    Documentation of Social Determinants of Health Among Individuals with Systemic Rheumatic and Musculoskeletal Diseases

    Sciaska Ulysse, Mia Chandler, Leah Santacroce, Tianrun Cai, Katherine Liao and Candace Feldman, Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Social determinants of health (SDoH), "the conditions in which people are born, grow, work, live, and age" (World Health Organization, 2022), directly influence health…
  • Abstract Number: 0845 • ACR Convergence 2022

    Predictors of Moderate-Vigorous Physical Activity Following a Physical Therapist Led Physical Activity Intervention for Adults with Total Knee Replacement

    Scott Jamieson1 and Christine Pellegrini2, 1The University of South Carolina, Arnold School of Public Health, Department of Exercise Science, Columbia, SC, 2University of South Carolina, Columbia, SC

    Background/Purpose: Following total knee replacement rehabilitation, patients are advised to participate in physical activity. Yet, most individuals at this stage do not increase their physical…
  • Abstract Number: 1639 • ACR Convergence 2022

    A Phase 3, 56-Week, Multicenter, Randomized, Double-Blind, Placebo Controlled Trial (OA-11) to Evaluate the Efficacy and Safety of a Single Injection of Lorecivivint Injected in the Target Knee Joint of Moderate to Severe Osteoarthritis Participants

    Yusuf Yazici1, Christopher Swearingen2, Heli Ghandehari3, Jon Britt4, ismail simsek5, Mark Fineman6, Sarah Kennedy2, Jeyanesh Tambiah7 and Timothy McAlindon8, 1New York University School of Medicine, La Jolla, CA, 2Biosplice Therapeutics, Inc, San Diego, CA, 3Biosplice Therapeutics, Inc., San Diego, CA, 4Biosplice Therapeutics, Inc., Los Angeles, CA, 5Alpine Immunesciences, San Diego, CA, 6Biosplice Therapeutics, San Diego, CA, 7Biosplice Ther Inc., San Diego, CA, 8Tufts Medical Center, Arlington, MA

    Background/Purpose: Knee osteoarthritis (OA) is a common joint disorder associated with pain, disability, and joint damage. There remains a large unmet need for treatments that…
  • Abstract Number: 1889 • ACR Convergence 2022

    Investigating a Possible Bi-Directional Causal Relationship Between Gout and Osteoarthritis for the European Population: Two-Sampled Mendelian Randomization Analysis Study

    Yun-Chen Tsai1, Yu-Jing Chang2, Che-Kai Chen2, Michael Doherty3, Weiya Zhang3 and Chang-Fu Kuo1, 1Chang Gung Memorial Hospital, Taoyuan, Taiwan, 2Center for Artificial Intelligence in Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan, 3University of Nottingham, Nottingham, United Kingdom

    Background/Purpose: Gout is the most common inflammatory arthritis, and osteoarthritis is the leading cause of arthritis globally. Gout and osteoarthritis frequently coexist in the same…
  • Abstract Number: 1905 • ACR Convergence 2022

    Does Exercise Before Surgery Predict Trajectories of Physical Activity After Knee Replacement?

    Jéssica Bianca Aily1, Dana Voinier1, Jason Jakiela1, Thomas Bye1, Hiral Master1, Louise Thoma2 and Daniel White1, 1University of Delaware, Newark, DE, 2UNC School of Medicine, Chapel Hill, NC

    Background/Purpose: Total knee replacement (TKR) is the definitive treatment for adults with knee osteoarthritis (OA) and is often successful in reducing pain and improving function.…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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