Abstracts tagged "osteoarthritis and x-ray"

Abstract Number: 1L • ACR/ARHP Annual Meeting 2017
Efficacy and Safety of Intra-Articular Sprifermin in Symptomatic Radiographic Knee Osteoarthritis: Results of the 2-Year Primary Analysis from a 5-Year Randomised, Placebo-Controlled, Phase II Study
Marc C. Hochberg¹, Ali Guermazi², Hans Guehring³, Aida Aydemir⁴, Stephen Wax⁵, Patricia Fleuranceau-Morel⁴, Asger Reinstrup Bihlet⁶, Inger Byrjalsen⁶, Jeppe Ragnar Andersen⁶ and Felix Eckstein⁷, ¹University of Maryland School of Medicine, Baltimore, MD, ²Boston Imaging Core Lab, LLC, and Boston University School of Medicine, Boston, MA, ³Merck KGaA, Darmstadt, Germany, ⁴EMD Serono Research & Development Institute, Inc. (a business of Merck KGaA, Darmstadt, Germany), Billerica, MA, ⁵EMD Serono Research & Development Institute, Inc. (a business of Merck KGaA, Darmstadt, Germany), BIllerica, MA, ⁶Nordic Bioscience, Herlev, Denmark, ⁷Institute of Anatomy, Paracelsus Medical University, Salzburg, Austria

Background/Purpose: Sprifermin, a novel recombinant human fibroblast growth factor-18 is currently investigated as a potential disease-modifying osteoarthritis (OA) drug. Two-year primary data from a 5-year…
Abstract Number: 1207 • ACR/ARHP Annual Meeting 2017
Clinical Relevance of Structural Measures in Knee Osteoarthritis: Baseline Values and Change from Baseline Discriminate Patients Subsequently Receiving Knee Replacement
C. Kent Kwoh¹, Hans Guehring², Michael J Hannon³ and Aida Aydemir⁴, ¹University of Arizona Arthritis Center, Tuscan, AZ, ²Merck KGaA, Darmstadt, Germany, ³Medicine, University of Pittsburgh, Pittsburgh, PA, ⁴EMD Serono Research & Development Institute, Inc. (a business of Merck KGaA, Darmstadt, Germany), Billerica, MA
Background/Purpose: Structural measures of knee OA (KOA) progression include assessment of radiographic joint space width (JSW) and quantitative MRI (qMRI) measurement of cartilage thickness, both…
Abstract Number: 202 • ACR/ARHP Annual Meeting 2014
Is Schuss View Alone Enough for the Diagnosis of Femorotibial Osteoarthritis ? the Khoala Cohort Study
Christian Roux¹, Bernard Mazieres², Evelyne Verrouil², Anne-Christine Rat,³, Patrice Fardellone⁴, Bruno Fautrel⁵, Jacques Pouchot⁶, Alain Saraux⁷, Francis Guillemin⁸, Liana Euller Ziegler⁹ and Joel Coste¹⁰, ¹Rhumatologie, Hopital Archet 1 - Université Nice Sophia Antipolis, Nice, France, ²CHU Toulouse, Toulouse, France, ³Université de Lorraine, Université Paris Descartes, Apemac, EA 4360, Nancy, France, ⁴Service de Rhumatologie, Hôpital Nord, C.H.U. d'Amiens, Amiens, France, ⁵CHU - Hôpital Pitié-Salpêtrière, Paris, France, ⁶Medecine Interne, Hopital Louis Mourier, Colombes, FRANCE, France, ⁷Rheumatology, CHU de la Cavale Blanche and Université Bretagne occidentale, Brest Cedex, France, ⁸INSERM, Centre d'Investigation Clinique - Epidémiologie Clinique (CIC-EC) CIE6, Nancy, France, ⁹151 rte de St Antoine de Gines, CHU de Nice -Université Nice Sophia Antipolis, Nice, France, ¹⁰CHU Hotel Dieu, Paris, France
Background/Purpose: Associating an anteroposterior (AP) extended-knee X-ray with a semiflexed AP or posteroanterior (PA) view is considered the gold standard for radiologically diagnosing tibiofemoral osteoarthritis…