Abstracts tagged "obesity"

Abstract Number: 1518 • 2018 ACR/ARHP Annual Meeting
Baricitinib and Tofacitinib in Real Life – Does Obesity Impact Response to Janus Kinase Inhibitor Therapy in Rheumatoid Arthritis?
Yvette Meißner¹, Lisa Baganz¹, Matthias Schneider², Ilka Schwarze³, Martin Feuchtenberger⁴, Angela Zink⁵ and Anja Strangfeld⁶, ¹Programme Area Epidemiology, German Rheumatism Research Center, Berlin, Germany, ²Policlinic for Rheumatology & Hiller Research Centre for Rheumatology, Department of Rheumatology & Hiller Research Unit, Medical Faculty, University Hospital, Heinrich-Heine-University Duesseldorf, Duesseldorf, Germany, ³Praxis internistische Rheumatologie, Leipzig, Germany, ⁴Rheumatologie/Klinische Immunologie, Kreiskliniken Altötting-Burghausen, Burghausen, Germany, ⁵Epidemiology Unit / Rheumatology and Clinical Immunology, German Rheumatism Research Centre (DRFZ) / Charité University Hospital, Berlin, Germany, ⁶Epidemiology, German Rheumatism Research Center, Berlin, Germany
Background/Purpose: The influence of obesity on treatment response of tumor necrosis factor inhibitors in patients with rheumatoid arthritis (RA) is described in literature, but data…
Abstract Number: 1547 • 2018 ACR/ARHP Annual Meeting
Impact of Obesity on Drug Survival of Tofacitinib in Patients with Rheumatoid Arthritis: Analysis from the Turkbio Registry
Hakan Babaoglu¹, Berna Goker¹, Nevsun İnanç², Merih Birlik³, Suleyman Serdar Koca⁴, Ayse Cefle⁵, Ediz Dalkiliç⁶, Abdurrahman Tufan¹, Sema Yilmaz⁷, Soner Senel⁸, Servet Akar⁹, Nurullah Akkoc¹⁰, Fatos Onen³ and Ummugulsum Gazel¹¹, ¹Internal Medicine-Rheumatology, Gazi University Faculty of Medicine, Ankara, Turkey, ²Rheumatology, Marmara University faculty of Medicine, İstanbul, Turkey, ³Rheumatology, Dokuz Eylul University Faculty of Medicine, İzmir, Turkey, ⁴Rheumatology, Firat University Faculty of Medicine, Elazığ, Turkey, ⁵Rheumatology, Kocaeli University, Faculty of Medicine, Kocaeli, Turkey, ⁶Department of Internal Medicine, Division of Rheumatology, Uludağ University Faculty of Medicine, Bursa, Turkey, ⁷Department of Rheumatology, Selcuk University School of Medicine, Konya, Turkey, ⁸Rheumatology, Kayseri Erciyes University, Faculty of Medicine, Kayseri, Turkey, ⁹Department of Internal Medicine, Division of Rheumatology,, Izmir Katip Çelebi University Faculty of Medicine, Izmir, Turkey, ¹⁰Rheumatology, İzmir, Turkey, İzmir, Turkey, ¹¹Rheumatology, Marmara University faculty of Medicine, Istanbul, Turkey
Background/Purpose: Several previous reports suggest that obesity impairs the effectiveness and drug survival of anti-TNF-α agents in rheumatoid arthritis (RA). The aim of the study…
Abstract Number: 1908 • 2018 ACR/ARHP Annual Meeting
Bariatric Surgery Does Not Affect the Incidence of Rheumatoid Arthritis in Obese Subjects
Yuan Zhang¹, Cristina Maglio², Anna Rudin³ and Lena Carlsson⁴, ¹Dep. of Rheumatology and Inflammation Research, The Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden, ²Dep. of Rheumatology and Inflammation Research and Wallenberg Centre for Molecular and Translational Medicine, The Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden, ³Dept of Rheumatology and Inflammation Research, The Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden, ⁴Department of Molecular and Clinical Medicine, The Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden
Background/Purpose: Obesity is among the risk factors for rheumatoid arthritis (RA). Bariatric surgery is an effective treatment to achieve weight loss and to prevent obesity-related…
Abstract Number: 1898 • 2017 ACR/ARHP Annual Meeting
Overweight/Obesity Affect Histological Features of Synovial Membrane of Rheumatoid Arthritis Patients from Disease Onset to Stable Remission Achievement
Stefano Alivernini¹, Barbara Tolusso¹, Maria Rita Gigante¹, Laura Bui², Clara Di Mario¹, Luca Petricca¹, Gabriele Di Sante¹, Roberta Benvenuto², Anna Laura Fedele¹, Francesco Federico², Gianfranco Ferraccioli³ and Elisa Gremese¹, ¹Institute of Rheumatology, Fondazione Policlinico Universitario A. Gemelli - Catholic University of the Sacred Heart, Rome, Italy, ²Institute of Pathology, Fondazione Policlinico Universitario A. Gemelli - Catholic University of the Sacred Heart, Rome, Italy, ³Institute of Rheumatology, Università Cattolica - Fondazione Policlinico Universitario A.Gemelli, Rome, Italy
Background/Purpose: Despite animal models, little is known about synovial tissue (ST) composition of overweight/obese Rheumatoid Arthritis patients. The aim of the study was to investigate…
Abstract Number: 1947 • 2017 ACR/ARHP Annual Meeting
Thy1 Is a Positive Regulator of Osteoblast Differentiation and Modulates Bone Homeostasis in Obese Mice
Ananta Paine¹, Collynn Woeller², Nelson Huertas¹, Maria de la Luz Garcia-Hernandez³, Richard Phipps² and Christopher T. Ritchlin⁴, ¹Department of Medicine, Division of Allergy, Immunology and Rheumatology, School of Medicine and Dentistry, University of Rochester, Rochester, New York, USA, Rochester, NY, ²Department of Environmental Medicine, School of Medicine and Dentistry,, Department of Environmental Medicine, School of Medicine and Dentistry, University of Rochester, Rochester, New York, USA, Rochester, NY, ³Department of Medicine,, Division of Allergy, Immunology and Rheumatology, School of Medicine and Dentistry, University of Rochester, Rochester, New York, USA, Rochester, NY, ⁴Division of Allergy, Immunology and Rheumatology, School of Medicine and Dentistry, Division of Allergy, Immunology and Rheumatology, School of Medicine and Dentistry, University of Rochester, Rochester, New York, USA, Rochester, NY
Background/Purpose: Thy1 (CD90) is a glycosylated, glycophosphatidylinositol (GPI)-anchored membrane protein originally identified as a marker for mouse T cells but subsequent reports noted expression on…
Abstract Number: 2263 • 2017 ACR/ARHP Annual Meeting
Obesity Independently Associates with Worse Patient Reported Outcomes in Women with Systemic Lupus Erythematosus
Sarah L. Patterson¹, Gabriela Schmajuk², Kashif Jafri³, Katherine D. Wysham³ and Patricia P. Katz⁴, ¹Division of Rheumatology, University of California, San Francisco, San Francisco, CA, ²San Francisco VA Medical Center, University of California San Francisco, San Francisco, CA, ³University of California, San Francisco, San Francisco, CA, ⁴Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA
Background/Purpose: Obesity has been shown to exacerbate systemic inflammation in the general population and contributes to worse disease-related outcomes in rheumatoid arthritis. The impact of…
Abstract Number: 2308 • 2017 ACR/ARHP Annual Meeting
The Prevalence of Comorbidities in Pediatric Psoriasis and Juvenile Psoriatic Arthritis
Cuoghi Edens¹, Angela Byun Robinson² and Maria Antonelli³, ¹Division of Pediatric Infectious Diseases and Rheumatology and Division of Rheumatology, Rainbow Babies and Children's Hospital and University Hospitals Cleveland Medical Center, Cleveland, OH, ²Division of Pediatric Infectious Diseases and Rheumatology, Case Western Reserve University School of Medicine, Rainbow Babies and Children’s Hospital, Cleveland, OH, ³Department of Medicine/Division of Rheumatology, Case Western Reserve University School of Medicine, MetroHealth Medical Center, Cleveland, OH
Background/Purpose: Adult-onset psoriasis (PsO) and psoriatic arthritis (PsA) have been associated with increased rates of diabetes, obesity, and hypertension. We sought to evaluate the prevalence…
Abstract Number: 2524 • 2017 ACR/ARHP Annual Meeting
Weight Change before and after Diagnosis in Patients with Psoriatic Arthritis, Rheumatoid Arthritis, and Ankylosing Spondylitis
Alexis Ogdie¹, Michael D. George², Joel Gelfand³, Maureen Dubreuil⁴, Thorvardur Love⁵ and Joshua Baker⁶, ¹Medicine/Rheumatology and Epidemiology, University of Pennsylvania, Philadelphia, PA, ²Division of Rheumatology, University of Pennsylvania, Philadelphia, PA, ³University of Pennsylvania Health System , Philadelphia, PA, ⁴Clinical Epidemiology, Boston University School of Medicine, Boston, MA, ⁵Landspitali University Hospital, Reykjavik, Iceland, ⁶Rheumatology, University of Pennsylvania, Philadelphia, PA
Background/Purpose: Rheumatoid arthritis (RA) has been associated with weight loss around the time of diagnosis; little is known about weight change around diagnosis in…
Abstract Number: 2770 • 2017 ACR/ARHP Annual Meeting
Using Fitbits. Fitabase®, and Remote Coaching to Increase Physical Activity in Employees with Knee Osteoarthritis Symptoms
Pamela Semanik¹, Julia (Jungwha) Lee², Christine Pellegrini³, Jing Song⁴ and Rowland W. Chang⁵, ¹College of Nursing, Rush University, Chicago, IL, ²Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, ³Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁴Center for Healthcare Studies, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁵Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL
Background/Purpose: Knee osteoarthritis (OA) affects approximately 6% of adults and is a leading cause of disability among U.S. adults. Physical activity (PA) is known to…
Abstract Number: 2851 • 2017 ACR/ARHP Annual Meeting
General and Abdominal Obesity As Risk Factors for Late-Life Mobility Limitation Among Women with Total Knee or Hip Replacement for Osteoarthritis
Aladdin Shadyab¹, Wenjun Li², Charles Eaton³ and Andrea LaCroix⁴, ¹Family Medicine and Public Health, University of California, San Diego, La Jolla, CA, ²Medicine, University of Massachusetts Medical School, Worcester, MA, ³Family Medicine and Epidemiology, Warren Alpert Medical School, School of Public Health, Brown University, Providence, RI, ⁴Family Medicine and Public Health, University of California, San Diego School of Medicine, La Jolla, CA
Background/Purpose: The population is rapidly aging, and by 2060, more than 12 million women will be ages 85 years and older in the United States.…
Abstract Number: 36 • 2017 Pediatric Rheumatology Symposium
The Association of Obesity with Pediatric Psoriatic Arthritis
Cynthia Manos¹, Rui Xiao², Timothy G. Brandon¹, Alexis Ogdie-Beatty³ and Pamela Weiss⁴, ¹Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA, ²Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA, ³Rheumatology, Hospital of the University of Pennsylvania, Philadelphia, PA, ⁴Division of Rheumatology, Center for Pediatric Clincial Effectiveness, Children's Hospital of Philadelphia, Philadelphia, PA
Background/Purpose: Obesity is associated with a significantly increased risk of inflammatory arthritis in adult patients with psoriasis. Obese adults with psoriatic arthritis (PsA) also…
Abstract Number: 3087 • 2016 ACR/ARHP Annual Meeting
Association of Weight Loss with Improved Disease Activity in Patients with Rheumatoid Arthritis
David J. Kreps^1,2, Florencia Halperin³, Sonali P. Desai³, Zhi Zhang³, Elena Losina³, Elizabeth W. Karlson¹, Bonnie L. Bermas¹ and Jeffrey A. Sparks⁴, ¹Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ²Boston University, Boston, MA, ³Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ⁴Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA
Background/Purpose : Obesity has been associated with worsened RA outcomes and increased disease activity. However, few longitudinal studies have investigated whether weight loss might improve…
Abstract Number: 3193 • 2016 ACR/ARHP Annual Meeting
Is an Intensive Diet and Exercise Regimen Cost-Effective for Obese and Overweight Patients with Symptomatic Knee OA?
Elena Losina¹, Karen C. Smith², A. David Paltiel³, Lisa Gale Suter⁴, Jeffrey N. Katz⁵ and Stephen P. Messier⁶, ¹Orthopedics, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ²Orthopaedics, Brigham and Women's Hospital, Boston, MA, ³Yale University, New Haven, CT, ⁴Medicine, Rheumatology, Yale University, New Haven, CT, ⁵Orthopaedics, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ⁶Department of Health and Exerc, Wake Forest University, Winston-Salem, NC
Background/Purpose: About 50% of persons with knee OA are obese. Quality-adjusted life-year losses due to knee OA and obesity exceed 3.5 per person. The results…
Abstract Number: 397 • 2016 ACR/ARHP Annual Meeting
Comorbidities Associated with Pediatric Psoriatic Arthritis
Cynthia Manos¹, Rui Xiao², Alexis Ogdie³, Timothy Brandon⁴ and Pamela F. Weiss^5,6, ¹Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA, ²Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA, ³University of Pennsylvania, Philadelphia, PA, ⁴Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, ⁵Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, ⁶Division of Rheumatology, Center for Pediatric Clincial Effectiveness, Children's Hospital of Philadelphia, Philadelphia, PA
Background/Purpose: In adults, psoriatic arthritis (PsA) is associated with an increased prevalence of obesity, hypertension, and diabetes. It is not yet known if pediatric patients…
Abstract Number: 1194 • 2016 ACR/ARHP Annual Meeting
Low Body Mass Index and Smoking Are Associated with a Lower Risk of Sarcoidosis: A Population-Based Nested Case-Control Study
Patompong Ungprasert¹, Cynthia S. Crowson² and Eric L. Matteson¹, ¹Rheumatology, Mayo Clinic, Rochester, MN, ²Health Sciences Research, Mayo Clinic, Rochester, MN
Low Body Mass Index and Smoking Are Associated With a Lower Risk of Sarcoidosis: A Population-Based Nested Case-Control Study Background/Purpose: Sarcoidosis is a systemic disorder…

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