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Abstracts tagged "obesity"

  • Abstract Number: 2114 • ACR Convergence 2024

    CT and DXA Bone Fragility Evaluation After Bariatric Surgery

    Marine FAUNY1, Marion Halin2, Edem Allado2, Laurent Brunaud2, Claire Nomine Criqui2, Eliane Albuisson2, Isabelle Chary-Valckenaere3, Damien Loeuille4 and Didier Quilliot2, 1CH TOUL, Toul, Lorraine, France, 2Nancy University Hospital, Vandoeuvre, Lorraine, France, 3Nancy University Hospital, Vandœuvre-lès-Nancy, Lorraine, France, 4Phd, Nancy Vandoeuvre, Lorraine, France

    Background/Purpose: Bariatric surgery could impact bone metabolism and induce significant changes, leading to increased bone resorption and an increased risk of fractures.The primary objective was…
  • Abstract Number: 2237 • ACR Convergence 2024

    The Association Between Bariatric Surgery and Incident Rheumatoid Arthritis

    Helana Jeries1, Revital Perlov Gavze2, Rula Daood3, Fadi Hassan3, Liat Lev shalem4, Ahmad Assalia5 and Mohammad E Naffaa3, 1Rheumatology Unit, Galilee Medical Center, Naharyia, Israel, Naharyia, HaZafon, Israel, 2Maccabi Healthcare Services, Tel Aviv, Israel, 3Rheumatology Unit, Galilee Medical Center, Naharyia, Israel, Naharyia, Israel, 4Maccabi Healthcare Services, Tel Aviv, HaMerkaz, Israel, 5Rambam Healthcare Campus, Haifa, HaZafon, Israel

    Background/Purpose: Obesity is considered a controversial risk factor for developing rheumatoid arthritis (RA), and the association between weight change and RA incidence is inconclusive. The…
  • Abstract Number: 2259 • ACR Convergence 2024

    Effects of Anti-Obesity Medications in RA Patients

    Elizabeth Dente1, David Kellner2, Vincent Tran2, Travis Welsh2, Victor Tran3, Angshuman Saha1, Jenny Brook1, David Elashoff4 and Veena Ranganath2, 1UCLA, Los Angeles, 2UCLA, Los Angeles, CA, 3UCLA, Costa Mesa, CA, 4UCLA Department of Medicine Statistics Core, Los Angeles

    Background/Purpose: It is standard practice to advocate for weight loss in patients with rheumatoid arthritis (RA) and obesity. Obesity and rheumatoid arthritis are both independently…
  • Abstract Number: 2350 • ACR Convergence 2024

    Do Smoking and Obesity Impact Secukinumab Treatment Outcomes? Real-world Data from 1,202 European Patients with Psoriatic Arthritis

    Zohra Faizy Ahmadzay1, Stylianos Georgiadis2, Mikkel Ostergaard3, Bente Glintborg4, Signe Møller-Bisgaard5, Marion Pons6, Jette Heberg7, Sara Nysom Christiansen8, Simon Horskjær Rasmussen6, Anne Gitte Loft9, Isabel Castrejon10, Lucia Otero-Varela11, Jakub Závada12, Karel Pavelka12, Jarno Rutanen13, Laura Kuusalo14, Michael Nissen15, Ziga Rotar16, Katja Perdan-Pikmajer16, Miguel Bernardes17, Bjorn Gudbjornsson18, Gerdur Gröndal18, Irene E. van der Horst-Bruinsma19, Karin Laas20, Brigitte Michelsen21, Catalin Codreanu22, Daniela DiGuiseppe23, Burkhard Moeller24, Gökçe Kenar25, Merete Hetland26 and Lykke Oernbjerg2, 1Rigshospitalet Glostrup and Copenhagen University, Glostrup, Denmark, 2Rigshospitalet Glostrup, Glostrup, Hovedstaden, Denmark, 3Department of Clinical Medicine, University of Copenhagen and Center for Rheumatology, Copenhagen Center for Arthritis Research, Glostrup, Denmark, 4DANBIO, Rigshospitalet Glostrup and University of Copenhagen, Virum, Denmark, 5Rigshospitalet, Glostrup and Slagelse Hospital, Glostrup, Denmark, 6Rigshospitalet Glostrup, Glostrup, Denmark, 7Rigshospitalet Glostrup, København V, Denmark, 8Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, Denmark., Glostrup, Denmark, 9Aarhus University Hospital and Aarhus University, Horsens, Denmark, 10Hospital General Universitario Gregorio Marañón and Complutense University of Madrid, Madrid, Spain, 11Spanish Society of Rheumatology, Madrid, Spain, 12Institute of Rheumatology and Charles University, Praha, Czech Republic, 13Tampere University Hospital, Tampere, Finland, 14University of Turku and Turku University Hospital, Turku, Finland, 15Geneva University Hospital, Geneva, Switzerland, 16University Medical Centre Ljubljana and University of Ljubljana, Ljubljana, Slovenia, 17São João Hospital Center and FMUP, Lisboa, Portugal, 18Landspitali University Hospital and University of Iceland, Reykjavik, Iceland, 19Department of Rheumatology, Radboud University Medical Centre, Nijmegen, Netherlands, 20East-Tallinn Central Hospital, Tallinn, Estonia, 21Rigshospitalet, Glostrup and Diakonhjemmet Hospital and Sørlandet Hospital, Kristiansand, Norway, 22University of Medicine and Pharmacy, Bucharest, Romania, 23Karolinska Institutet, Stockholm, 24Inselspital - University Hospital Bern, Bern, Switzerland, 25Dokuz Eylul University School of Medicine, Izmir, Turkey, 26Rigshospitalet Glostrup and University of Copenhagen, Glostrup, Denmark

    Background/Purpose: Smoking and obesity are common in patients with psoriatic arthritis (PsA) and can lead to higher disease activity and poorer response to treatment with…
  • Abstract Number: 2386 • ACR Convergence 2024

    Landscape of Immune Cells and Autoimmunity in Systemic Lupus Erythematosus Patients with Obesity

    Alexandra Reese1, Chandana Keshavamurthy2, Sneha Centala1, Samantha Ahrens1, Shivani Shah2, Douglas Reeves2, William Davis3, Robert Quinet4, Jerald Zakem1, Qingli Wu1, Kimmy Tran1, Teresa Leeth5, Daniyal Nadeem6, Sarwat Umer7, Samina Hayat5 and Xin Zhang1, 1Ochsner Health, New Orleans, LA, 2Ochsner Clinic Foundation, New Orleans, 3Ochsner Health System, New Orleans, LA, 4Ochsner Health, River Ridge, LA, 5Louisiana State University Shreveport, Shreveport, LA, 6LSU Shreveport, Shreveport, 7LSU HEALTH SHREVEPORT, SHREVEPORT, LA

    Background/Purpose: Systemic lupus erythematosus (SLE) is an inflammatory autoimmune disease characterized by autoantibodies and disruption of multiple organs due to immunomodulatory dysfunction. Obesity is a…
  • Abstract Number: 0294 • ACR Convergence 2024

    Obesity and Risk of Autoimmune Diseases: Insights from the National Inpatient Sample

    Sami Rabah and Xiangyi Kang, Lincoln Medical Center, New York, NY

    Background/Purpose: Obesity has been implicated as a risk factor in developing various cardiovascular, respiratory, and other health complications. However, the link between obesity and autoimmune…
  • Abstract Number: 0310 • ACR Convergence 2023

    Implementing an Osteoarthritis Management Program to Deliver Guideline-Driven Care for Knee and Hip Osteoarthritis in a U.S. Academic Health System

    Kathryn Miller1, Divya Vundamati2, Linda Baier1, Roger Brown1, Tommy Yue Yu1 and Christie M. Bartels3, 1University of Wisconsin, Madison, WI, 2UW Health, Madison, WI, 3University of Wisconsin, School of Medicine and Public Health, Madison, WI

    Background/Purpose: To assess patient outcomes from an Osteoarthritis Management Program (OAMP) situated in an academic medical center.Methods: Eligibility for this open cohort study included adults…
  • Abstract Number: 0397 • ACR Convergence 2023

    Obesity Is Associated with Worse Flare Symptoms and Quality of Life in Early Rheumatoid Arthritis: Insights from the RA Flare Questionnaire

    Margaret Butler1, Carlos Aude2, Clifton Bingham3 and Vivian Bykerk1, 1Hospital for Special Surgery, New York, NY, 2Hospital for Special Surgery, Weill Cornell Medicine, New York, NY, 3Johns Hopkins University, Baltimore, MD

    Background/Purpose: Elevated BMI has been previously associated with lower RA remission rates and underascertainment of swollen joint counts.1,2 However, a knowledge gap persists regarding the…
  • Abstract Number: 0406 • ACR Convergence 2023

    Obesity Is a Risk Factor for Poor Response to Treatment in Early Rheumatoid Arthritis – a NORD-STAR Spin-Off Study

    Violetta Dubovyk1, Gerdur Maria Grondal2, Bjorn Gudbjornsson3, Espen A Haavardsholm4, Marte Schrumpf Heiberg4, Merete Hetland5, Kim Hørslev-Petersen6, Meliha Kapetanovic7, Alf Kastbom8, John Lampa9, Kristina Lend10, Dan Nordstrom11, Michael Nurmohamed12, Milad Rizk13, Annika Söderbergh14, Till Uhlig15, Mikkel Østergaard16, Ronald van Vollenhoven12, Anna Rudin17 and Cristina Maglio18, 1University of Gothenburg, Gothenburg, Sweden, 2Department for Rheumatology, Landspitali University Hospital, Reykjavik, Iceland, 3Centre for Rheumatology Research, University Hospital, Reykjavik, Iceland, 4Diakonhjemmet Hospital, Oslo, Norway, 5Copenhagen Center for Arthritis Research, Rigshospitalet, Copenhagen, Denmark, 6University of Southern Denmark, Odense, Denmark, 7Lund University and Skåne University Hospital, Lund, Sweden, 8Linköping University, Linköping, Sweden, 9Stockholm County, Hãsselby, Sweden, 10Amsterdam UMC, Karolinska Institute, Stockholm, Sweden, 11Helsinki University Hospital, Helsinki, Finland, 12Amsterdam University Medical Centers, Amsterdam, Netherlands, 13Västmanlands Hospital Västerås, Västerås, Sweden, 14Örebro University Hospital, Örebro, Sweden, 15Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway, 16Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet; University of Copenhagen, Copenhagen, Denmark, 17Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden, 18Institute of Medicine, University of Gothenburg, Gothenburg, Sweden

    Background/Purpose: Several therapeutic options are currently available to treat rheumatoid arthritis (RA); however, the response to treatment is highly variable, and not all patients achieve…
  • Abstract Number: 0987 • ACR Convergence 2023

    Risk Factors and Predictors of Disease Activity in Rheumatoid Arthritis and Psoriatic Arthritis: Data from the Mexican Adverse Events Registry (BIOBADAMEX)

    Vijaya Rivera Terán1, David Vega Morales2, Miguel Angel Saavedra Salinas3, Iris Colunga4, Sandra Carrillo Vazquez5, Dafhne Miranda Hernández6, Sergio Durán Barragán7, Erick Adrián Zamora Tehozol8, Daniel Xavier Xibillé Friedman9, Angel Alejandro Castillo Ortiz10, Sandra Sicsik Ayala11, Fedra Irazoque Palazuelos5, Julio César Casasola Vargas12, Angelica Peña13, Omar Eloy Muñoz Monroy14, Azucena Ramos Sánchez2, Luis Valdés Corona15, Javier Merayo-Chalico16, Estefania Torres Valdez13, Aleni Paz Viscarra15, Samara Mendieta Zerón17 and Deshiré Alpízar Rodríguez1, 1Colegio Mexicano de Reumatología, Mexico City, Mexico, 2Instituto Mexicano del Seguro Social, Monterrey, Mexico, 3IMSS, Mexico City, Mexico, 4Hospital Universitario UANL, Monterrey, Mexico, 5Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado, Mexico City, Mexico, 6Instituto Mexicano del Seguro Social, Mexico City, Mexico, 7Consulta Privada, Guadalajara, Mexico, 8Centro Médico Pensiones, Mérida, Mexico, 9Práctica Privada, Cuernavaca, Mexico, 10Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado, Mérida, Mexico, 11Instituto Mexicano del Seguro Social, Torreón, Mexico, 12Instituto de Seguridad Social del Estado de México y Municipios, Mexico City, Mexico, 13Instituto Mexicano del Seguro Social, Querétaro, Mexico, 14Hospital Central Militar, Mexico City, Mexico, 15Práctica Privada, Mexico City, Mexico, 16Reumátika, Centro de Vanguardia en Reumatología de la Ciudad de México, Mexico City, Mexico, 17Instituto de Seguridad Social del Estado de México y Municipios, Toluca, Mexico

    Background/Purpose: Genetic, demographic, clinical, and immunological factors have been related with the response to treatment in inflammatory rheumatic diseases, such as rheumatoid arthritis (RA) and…
  • Abstract Number: 1414 • ACR Convergence 2023

    Effects of Apremilast on Changes in Cardiometabolic Parameters by Diabetes and Obesity Status in Patients with Psoriatic Arthritis

    Philip J. Mease1, Dafna Gladman2, Iain McInnes3, Sue Cheng4, Stephen Colgan5, Yuri Klyachkin6, Lichen Teng7 and Nehal Mehta8, 1Swedish Medical Center/Providence St. Joseph Health and University of Washington School of Medicine, Seattle, WA, 2Schroeder Arthritis Institute, Krembil Research Institute, Toronto Western Hospital, Department of Medicine, University of Toronto, Toronto, ON, Canada, 3University of Glasgow, Glasgow, United Kingdom, 4Amgen, Inc., Bradenton, FL, 5Amgen, Inc., Halton Hills, ON, Canada, 6Amgen, Inc., Lexington, KY, 7Amgen, Inc., Thousand Oaks, CA, 8George Washington University School of Medicine, Washington, DC

    Background/Purpose: The prevalence of cardiometabolic diseases including obesity and diabetes is higher in patients with psoriatic arthritis (PsA) than those without PsA. Apremilast (APR) is…
  • Abstract Number: 1457 • ACR Convergence 2023

    Obesity Is an Independent Poor Prognostic Factor in Lupus Nephritis

    Francy Milena Cuervo Gutiérrez1, Antoine Enfrein2, Frederic Houssiau3 and Farah Tamirou4, 1Fundacion Santa Fe de Bogota, Bogotá, Colombia, 2CHU de Nantes, Nantes, France, 3CUSL - UCLouvain, Brussels, Belgium, 4UCLouvain - Cliniques universitaires Saint-Luc, Brussels, Belgium

    Background/Purpose: Up to 50% of patients suffering from systemic lupus erythematosus (SLE) develop lupus nephritis (LN) within the first 10 years of diagnosis and 5…
  • Abstract Number: 1475 • ACR Convergence 2023

    Retrospective Study of Obesity on Clinical and Immunological Features in Systemic Lupus Erythematosus Using AI Software Deep 6 and EPIC Slicer Dicer

    Shivani Shah1, chandana keshavamurthy1, Samantha Ahrens1, Douglas Reeves1, William Davis1, Robert Quinet1, Jerald Zakam1, Samina Hayat2, Teresa Leeth2, Sarwat Umer3, Sulman Hasan2, Maria Latsis2, Xin Zhang1 and Gitanjali Lobo4, 1Ochsner Health, New Orleans, LA, 2Louisiana State University, Shreveport, LA, 3LSU Health Shreveport, Shreveport, LA, 4Ochsner Clinic Foundation, Baton Rouge, LA

    Background/Purpose: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by autoantibodies and systemic inflammation, affecting multiple organs especially kidney. Environmental factors, genetic predisposition,…
  • Abstract Number: 1591 • ACR Convergence 2023

    Complement Factor D/Adipsin Knockout Mice Demonstrate Disparate Pain and Structural Damage Phenotypes in Obesity-induced Post Traumatic Osteoarthritis

    Kelsey Collins1, Kristin Lenz2, Arin Oestreich2, Luke Springer2, Antonina Akk2, Huimin Yan2, Xiaobo Wu2, John Atkinson3, Christine Pham4 and Farshid Guilak4, 1University of California San Francisco, San Francisco, CA, 2Washington University in St. Louis, St. Louis, MO, 3Washington University School of Medicine, St. Louis, MO, 4Washington University, St. Louis, MO

    Background/Purpose: Osteoarthritis (OA) is the leading cause of musculoskeletal pain, which is a primary driver of care-seeking behavior. There is lack of mechanistic information detailing…
  • Abstract Number: 1939 • ACR Convergence 2023

    Sinonasal Sarcoidosis Associated with Chronic Pulmonary Disease, Deficiency Anemias, and Obesity

    Emily Kokush, Mary Salim, Eugenio Capitle, Reena Khianey and Evelyne Kalyoussef, Rutgers New Jersey Medical School, Newark, NJ

    Background/Purpose: Sarcoidosis is a systemic granulomatous inflammatory disease that can involve multiple organ systems. Rarely, sarcoidosis can involve the upper respiratory tract including the sinonasal…
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