ACR Meeting Abstracts

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Abstracts tagged "obesity"

  • Abstract Number: 2259 • ACR Convergence 2024

    Effects of Anti-Obesity Medications in RA Patients

    Elizabeth Dente1, David Kellner2, Vincent Tran2, Travis Welsh2, Victor Tran3, Angshuman Saha1, Jenny Brook1, David Elashoff4 and Veena Ranganath2, 1UCLA, Los Angeles, 2UCLA, Los Angeles, CA, 3UCLA, Costa Mesa, CA, 4UCLA Department of Medicine Statistics Core, Los Angeles

    Background/Purpose: It is standard practice to advocate for weight loss in patients with rheumatoid arthritis (RA) and obesity. Obesity and rheumatoid arthritis are both independently…
  • Abstract Number: 2350 • ACR Convergence 2024

    Do Smoking and Obesity Impact Secukinumab Treatment Outcomes? Real-world Data from 1,202 European Patients with Psoriatic Arthritis

    Zohra Faizy Ahmadzay1, Stylianos Georgiadis2, Mikkel Ostergaard3, Bente Glintborg4, Signe Møller-Bisgaard5, Marion Pons6, Jette Heberg7, Sara Nysom Christiansen8, Simon Horskjær Rasmussen6, Anne Gitte Loft9, Isabel Castrejon10, Lucia Otero-Varela11, Jakub Závada12, Karel Pavelka12, Jarno Rutanen13, Laura Kuusalo14, Michael Nissen15, Ziga Rotar16, Katja Perdan-Pikmajer16, Miguel Bernardes17, Bjorn Gudbjornsson18, Gerdur Gröndal18, Irene E. van der Horst-Bruinsma19, Karin Laas20, Brigitte Michelsen21, Catalin Codreanu22, Daniela DiGuiseppe23, Burkhard Moeller24, Gökçe Kenar25, Merete Hetland26 and Lykke Oernbjerg2, 1Rigshospitalet Glostrup and Copenhagen University, Glostrup, Denmark, 2Rigshospitalet Glostrup, Glostrup, Hovedstaden, Denmark, 3Department of Clinical Medicine, University of Copenhagen and Center for Rheumatology, Copenhagen Center for Arthritis Research, Glostrup, Denmark, 4DANBIO, Rigshospitalet Glostrup and University of Copenhagen, Virum, Denmark, 5Rigshospitalet, Glostrup and Slagelse Hospital, Glostrup, Denmark, 6Rigshospitalet Glostrup, Glostrup, Denmark, 7Rigshospitalet Glostrup, København V, Denmark, 8Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, Denmark., Glostrup, Denmark, 9Aarhus University Hospital and Aarhus University, Horsens, Denmark, 10Hospital General Universitario Gregorio Marañón and Complutense University of Madrid, Madrid, Spain, 11Spanish Society of Rheumatology, Madrid, Spain, 12Institute of Rheumatology and Charles University, Praha, Czech Republic, 13Tampere University Hospital, Tampere, Finland, 14University of Turku and Turku University Hospital, Turku, Finland, 15Geneva University Hospital, Geneva, Switzerland, 16University Medical Centre Ljubljana and University of Ljubljana, Ljubljana, Slovenia, 17São João Hospital Center and FMUP, Lisboa, Portugal, 18Landspitali University Hospital and University of Iceland, Reykjavik, Iceland, 19Department of Rheumatology, Radboud University Medical Centre, Nijmegen, Netherlands, 20East-Tallinn Central Hospital, Tallinn, Estonia, 21Rigshospitalet, Glostrup and Diakonhjemmet Hospital and Sørlandet Hospital, Kristiansand, Norway, 22University of Medicine and Pharmacy, Bucharest, Romania, 23Karolinska Institutet, Stockholm, 24Inselspital - University Hospital Bern, Bern, Switzerland, 25Dokuz Eylul University School of Medicine, Izmir, Turkey, 26Rigshospitalet Glostrup and University of Copenhagen, Glostrup, Denmark

    Background/Purpose: Smoking and obesity are common in patients with psoriatic arthritis (PsA) and can lead to higher disease activity and poorer response to treatment with…
  • Abstract Number: 2386 • ACR Convergence 2024

    Landscape of Immune Cells and Autoimmunity in Systemic Lupus Erythematosus Patients with Obesity

    Alexandra Reese1, Chandana Keshavamurthy2, Sneha Centala1, Samantha Ahrens1, Shivani Shah2, Douglas Reeves2, William Davis3, Robert Quinet4, Jerald Zakem1, Qingli Wu1, Kimmy Tran1, Teresa Leeth5, Daniyal Nadeem6, Sarwat Umer7, Samina Hayat5 and Xin Zhang1, 1Ochsner Health, New Orleans, LA, 2Ochsner Clinic Foundation, New Orleans, 3Ochsner Health System, New Orleans, LA, 4Ochsner Health, River Ridge, LA, 5Louisiana State University Shreveport, Shreveport, LA, 6LSU Shreveport, Shreveport, 7LSU HEALTH SHREVEPORT, SHREVEPORT, LA

    Background/Purpose: Systemic lupus erythematosus (SLE) is an inflammatory autoimmune disease characterized by autoantibodies and disruption of multiple organs due to immunomodulatory dysfunction. Obesity is a…
  • Abstract Number: 0294 • ACR Convergence 2024

    Obesity and Risk of Autoimmune Diseases: Insights from the National Inpatient Sample

    Sami Rabah and Xiangyi Kang, Lincoln Medical Center, New York, NY

    Background/Purpose: Obesity has been implicated as a risk factor in developing various cardiovascular, respiratory, and other health complications. However, the link between obesity and autoimmune…
  • Abstract Number: 0388 • ACR Convergence 2024

    The Association Between Body Composition and Disease and Treatment Outcomes in Patients with Juvenile Idiopathic Arthritis: Results from the CAPRI Registry

    Samantha Morin1, KAREN BEATTIE2, Roxana Bolaria3, Tania Cellucci4, Gaelle Chedeville5, Amieleena Chhabra6, Paul Dancey7, Tommy Gerschman8, Liane Heale9, Julie Herrington2, Adam Huber10, Mehul Jariwala11, Jean-Philippe Proulx-Gauthier12, Dax Rumsey13, Heinrike Schmeling14, Jaime Guzman15 and Michelle Batthish4, and CAPRI Registry Investigators, 1McMaster University, Hamilton, Canada, 2McMaster University, Hamilton, ON, Canada, 3Victoria Arthritis Center, Victoria, BC, Canada, 4McMaster Children's Hospital, Hamilton, ON, Canada, 5The Montreal Children's Hospital, Montreal, QC, Canada, 6University of British Columbia, Penticton, BC, Canada, 7Memorial University, St. John's, Canada, 8University of British Columbia - Vancouver, North Vancouver, BC, Canada, 9McMaster University, Oakville, ON, Canada, 10IWK Health Centre, Halifax, NS, Canada, 11Jim Pattison Children's Hospital, Saskatoon, Canada, 12CHU de Quebec - Universite Laval, Quebec, QC, Canada, 13University of Alberta, Edmonton, AB, Canada, 14University of Calgary, Calgary, AB, Canada, 15University of British Columbia and BC Children's Hospital, Vancouver, BC, Canada

    Background/Purpose: Recent evidence has linked abnormal body weight, underweight or obesity, with poor disease outcomes in adults with inflammatory arthritis. Yet, little is known about…
  • Abstract Number: 0438 • ACR Convergence 2024

    Overweight and Obesity Are Key Modifiable Risk Factors for Adverse Outcomes in SLE Pregnancies

    Jessica Boivin1, Karim Sacre2, Sasha Bernatsky3, Ann E. Clarke4, Megan Barber4, Paul Fortin5, John Hanly6, Alexandra Legge7, Sang-Cheol Bae8 and Evelyne Vinet9, 1McGill University, Montreal, QC, Canada, 2Université de Paris, Paris, France, 3Research Institute of the McGill University Health Centre, Montreal, QC, Canada, 4Division of Rheumatology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada, 5Centre ARThrite - CHU de Québec - Université Laval, Quebec, QC, Canada, 6Dalhousie University, Halifax, NS, Canada, Halifax, NS, Canada, 7Dalhousie University, Halifax, NS, Canada, 8Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Republic of Korea, 9McGill University Health Centre, Montreal, QC, Canada

    Background/Purpose: High maternal body mass index (BMI) is a well-established modifiable risk factor for adverse pregnancy outcomes (APO) in the general obstetric population. Best practices…
  • Abstract Number: 0457 • ACR Convergence 2024

    Metabolic Syndrome, Adipokines, and Response to Advanced Therapies in Rheumatoid Arthritis

    Joshua Baker1, George Reed2, Geoffrey Thiele3, Dimitrios Pappas4, christina Charles-Schoeman5, Monica Guma6, Leslie Harrold7, Jeffrey Curtis8 and Joel Kremer9, 1Department of Medicine, Perelman School of Medicine University of Pennsylvania, Philadelphia, PA, 2University of Massachusetts Chan Medical School, Worcester, MA, 3University of Nebraska Medical Center, Omaha, NE, 4CorEvitas, New York, NY, 5UCLA Medical Center, Santa Monica, CA, 6UCSD, La Jolla, CA, 7CorEvitas, Northborough, MA, 8University of Alabama at Birmingham, Hoover, AL, 9The Corrona Research Foundation, Delray Beach, FL

    Background/Purpose: While BMI has been associated with response to therapy in several studies in rheumatoid arthritis (RA), it is not a comprehensive measure of the…
  • Abstract Number: 0864 • ACR Convergence 2024

    Obesity Subtypes and Trajectories of Functional Change After 7-years of Follow-up: The Multicenter Osteoarthritis (MOST) Study

    Kristine Godziuk1, Sarah Tilley2, mike LaValley3, Michael Nevitt4, C.E. Lewis5, James Torner6 and Tuhina Neogi2, 1University of Alberta, Edmonton, AB, Canada, 2Boston University Chobanian & Avedisian School of Medicine, Boston, MA, 3Boston University School of Public Health, Arlington, MA, 4UCSF, Orinda, CA, 5University of Alabama at Birmingham, Birmingham, AL, 6University of Iowa, Iowa City

    Background/Purpose: People with knee osteoarthritis (OA) and obesity (i.e. BMI ≥30kg/m2) have poorer function than those without obesity. However, function is not uniform among people…
  • Abstract Number: 1050 • ACR Convergence 2024

    The Cost-effectiveness of Glucagon-Like Peptide-1 Receptor Agonists (GLP1RAs) for Patients with Knee Osteoarthritis and Obesity

    Daniel Betensky1, Jeffrey Katz1, Catherine Yang2, David Hunter3, Jamie Collins1, Candace Feldman1, Karen Smith1, Stephen Messier4, Jason Kim5, Faith Selzer6 and Elena Losina1, 1Brigham and Women's Hospital, Boston, MA, 2Brigham and Women's Hospital, Brookline, MA, 3Sydney Musculoskeletal Health, University of Sydney, St Leonards, New South Wales, Australia, 4Wake Forest University, Winston Salem, NC, 5Arthritis Foundation, Atlanta, GA, 6Brigham and Women's Hospital, Amesbury, MA

    Background/Purpose: Weight-loss has been shown to alleviate knee osteoarthritis (OA) symptoms in persons with OA and obesity. Utilization of GLP1RA medications has increased rapidly. These…
  • Abstract Number: 1187 • ACR Convergence 2024

    Association of Depressive Symptoms and Multiple Joint Osteoarthritis with Pain Outcomes in the WE-CAN Trial

    Natalie Allcott1, Stephen Messier2, Shannon Mihalko2, Jeffrey Katz3, Paul DeVita4, David Hunter5, Sara Quandt6, Carolina Alvarez7, Leigh Callahan8 and Amanda Nelson1, 1University of North Carolina at Chapel Hill, Chapel Hill, NC, 2Wake Forest University, Winston Salem, NC, 3Brigham and Women's Hospital, Brookline, MA, 4Eastern Carolina University, Greenville, 5Sydney Musculoskeletal Health, University of Sydney, St Leonards, New South Wales, Australia, 6Wake Forest University, Winston-Salem, 7University of North Carolina at Chapel Hill, Miami, FL, 8University of North Carolina Thurston Arthritis Research Center, Chapel Hill, NC

    Background/Purpose: The Weight-loss and Exercise for Communities with Arthritis in North Carolina (WE-CAN) trial was a community-based, pragmatic randomized clinical trial in men and women…
  • Abstract Number: 1192 • ACR Convergence 2024

    Relationship Between Measures of Fat Mass and Knee Osteoarthritis Incidence: The Multicenter Osteoarthritis (MOST) Study

    Kristine Godziuk1, Sarah Tilley2, mike LaValley3, Douglas Kiel4, Michael Nevitt5, C.E. Lewis6, James Torner7 and Tuhina Neogi2, 1University of Alberta, Edmonton, AB, Canada, 2Boston University Chobanian & Avedisian School of Medicine, Boston, MA, 3Boston University School of Public Health, Arlington, MA, 4Hebrew SeniorLife and Department of Medicine Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, 5UCSF, Orinda, CA, 6University of Alabama at Birmingham, Birmingham, AL, 7University of Iowa, Iowa City

    Background/Purpose: Obesity [defined by body mass index (BMI) ≥30 kg/m2] is an established risk factor for incident radiographic knee OA (ROA). However, the relative contributions…
  • Abstract Number: 1379 • ACR Convergence 2024

    Association Between Body Mass Index and the Persistence of Non-TNF-Targeted Biologics in Patients with Rheumatoid Arthritis

    Dong-Jin Park1, Hyemin Jeong2, Sung-Eun Choi3, Ji-Hyoun Kang2 and Shin-Seok Lee4, 1Chonnam National University Medical School and Hospital, Gwangju, South Korea, 2Chonnam National University Hospital, Gwangju, South Korea, 3Chonnam National University Medical School & Hospital, Gwangju, South Korea, 4Division of Rheumatology, Department of Internal Medicine, Chonnam National University Medical School and Hospital, Gwangju, KR, Gwangju, Republic of Korea

    Background/Purpose: Recent studies have shown the impact of obesity on achieving low disease activity (LDA) or remission in rheumatoid arthritis (RA) patients treated with TNF…
  • Abstract Number: 1484 • ACR Convergence 2024

    A Retrospective Evaluation of Glucagon-like Peptide-1 Receptor Agonists in SLE Patients

    Philip Carlucci1, Brooke Cohen2, Amit Saxena3, H Michael Belmont3, Mala Masson4, Heather Gold5, Jill Buyon2 and Peter Izmirly6, 1New York University School of Medicine, New York, NY, 2NYU Grossman School of Medicine, New York, NY, 3NYU School of Medicine, New York, NY, 4NYU Langone Health, New York, NY, 5NYU Langone Health, NYC, 6New York University Grossman School of Medicine, New York, NY

    Background/Purpose: Glucagon-like peptide-1 receptor agonists (GLP1-RA) are an emerging class of medications that significantly improve cardiometabolic outcomes. Whether these drugs may be useful in mitigating…
  • Abstract Number: 1891 • ACR Convergence 2024

    Association of Physical Activity Levels on Chronic Opioid Use in Radiographic Axial Spondylitis Patients

    Rutvin Kyada1, Jean Liew2, Maureen Dubreuil3, Matthew Brown4, Mariko Ishimori5, John Reveille6, Michael Ward7, Michael Weisman8 and Lianne S Gensler9, 1Boston University, Boston, MA, 2Boston University Chobanian & Avedisian School of Medicine, Boston, MA, 3Section of Rheumatology, Boston University School of Medicine, Boston, MA, 4King's College London, London, United Kingdom, 5Cedars-Sinai Health System, Los Angeles, CA, 6UTHealth Houston Division of Rheumatology, Houston, 7NIH, Bethesda, MD, 8Stanford University, Los Angeles, CA, 9Department of Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA

    Background/Purpose: Pain remains a common symptom of axial spondyloarthritis (axSpA) despite availability of effective therapies. Physical activity may benefit pain and is guideline recommended but…
  • Abstract Number: 2114 • ACR Convergence 2024

    CT and DXA Bone Fragility Evaluation After Bariatric Surgery

    Marine FAUNY1, Marion Halin2, Edem Allado2, Laurent Brunaud2, Claire Nomine Criqui2, Eliane Albuisson2, Isabelle Chary-Valckenaere3, Damien Loeuille4 and Didier Quilliot2, 1CH TOUL, Toul, Lorraine, France, 2Nancy University Hospital, Vandoeuvre, Lorraine, France, 3Nancy University Hospital, Vandœuvre-lès-Nancy, Lorraine, France, 4Phd, Nancy Vandoeuvre, Lorraine, France

    Background/Purpose: Bariatric surgery could impact bone metabolism and induce significant changes, leading to increased bone resorption and an increased risk of fractures.The primary objective was…
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