Abstracts tagged "neuropsychiatric disorders"

Abstract Number: 2831 • 2013 ACR/ARHP Annual Meeting
Increased Risk Of Autism Spectrum Disorders In Children Born To Women With SLE: Preliminary Data From The O S L E R Cohort
Evelyne Vinet¹, Susan Scott², Christian A. Pineau³, Lawrence Joseph⁴, Ann E. Clarke⁵, Eric Fombonne⁶, Robert W. Platt⁴ and Sasha Bernatsky⁷, ¹McGill University Health Center, Montreal, QC, Canada, ²McGill University Health Centre, Montreal, QC, Canada, ³Rheumatology, McGill University Health Center, Montreal, QC, Canada, ⁴McGill University, Montreal, QC, Canada, ⁵Division of Rheumatology, University of Calgary, Alberta, Calgary, AB, Canada, ⁶Oregon Health and Sciences University, Portland, OR, ⁷Division of Clinical Epidemiology, McGill University Health Center, Montreal, QC, Canada
Background/Purpose: Recent experimental data suggest in utero exposure to maternal antibodies and cytokines as important risk factors for autism spectrum disorders (ASD). Interestingly, women with…
Abstract Number: 1716 • 2013 ACR/ARHP Annual Meeting
Childhood-Onset Systemic Lupus Erythematosus With Clinical Neurocognitive Dysfunction Have Lower Nodal Density and Connectivity On Diffusion Tensor Imaging
Jordan T. Jones¹, Mark DiFrancesco², Ahmad I. Zaal¹, Marisa S. Klein-Gitelman³, Darren Gitelman⁴, Jun Ying⁵ and Hermine Brunner¹, ¹Pediatric Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ³Division of Rheumatology, Children's Memorial Hospital, Chicago, IL, ⁴Neurology, Northwestern University, Chicago, IL, ⁵Medicine-Internal Medicine-General Medicine, University of Cincinnati, Cincinnati, OH
Background/Purpose: Neurocognitive dysfunction (NCD) is common in childhood-onset systemic lupus erythematosus (cSLE), and often difficult to detect with current resources. Diffusion tensor imaging (DTI) is…
Abstract Number: 312 • 2012 ACR/ARHP Annual Meeting
Blood-Based Biomarkers of Neurocognitive Dysfunction in Childhood-Onset Systemic Lupus Erythematosus
Hermine Brunner¹, Jessica Hummel², Shannen Nelson³, Erin C. Thomas⁴, Jennifer L. Huggins¹, Megan L. Curran⁵, Jun Ying⁶ and Marisa S. Klein-Gitelman⁷, ¹Pediatric Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ³Rheumatology, Cincinnati Children's Hospital, Cincinnati, OH, ⁴Division of Rheumatology, Anne & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, ⁵Division of Pediatric Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁶Medicine-Internal Medicine-General Medicine, University of Cincinnati, Cincinnati, OH, ⁷Division of Rheumatology, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL
Background/Purpose: Several brain-reactive autoantibodies in the blood have been inconsistently associated with Neuropsychiatric Systemic Lupus Erythematosus (NPSLE) in adults but very little is known whether…
Abstract Number: 286 • 2012 ACR/ARHP Annual Meeting
The Association of N-Methyl-D-Aspartate Receptor Antibodies and Neurocognitive Dysfunction in Pediatric Lupus Patients and in the Offspring of Adult Patients with Lupus
Natasha M. Ruth¹, Mary C. Kral², Stephanie Slan³, Tamara K. Nowling⁴, Murray H. Passo¹ and Gary S. Gilkeson³, ¹Pediatric Rheumatology, Medical University of South Carolina, Charleston, SC, ²Genetics and Developmental Pediatrics, MUSC, Charleston, SC, ³Department of Medicine, Division of Rheumatology, Medical University of South Carolina, Charleston, SC, ⁴Medical University of South Carolina, Charleston, SC
Background/Purpose: Approximately 1/5 of all systemic lupus erythematosus (SLE) starts in childhood and central nervous system (CNS) dysfunction is more common in childhood-onset SLE. CNS…

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