ACR Meeting Abstracts

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Abstracts tagged "neurology"

  • Abstract Number: 0601 • ACR Convergence 2025

    Precipitants and Long-Term Outcomes of Posterior Reversible Encephalopathy Syndrome in Systemic Lupus Erythematosus: A Multicenter Cohort Study and Systematic Review

    Ali Ardekani1, Alain Sanchez-Rodriguez2, Mariana González-Treviño3, Jose Meade-Aguilar4, Maria O. Valenzuela-Almada5, Hannah Langenfeld1, Larry J. Prokop4, Isabel Valenzuela Almada6, Gabriel Figueroa-Parra7, Nicolás Sánchez Domínguez8, Alejandro A. Rabinstein4, M. Hassan Murad4, Cynthia Crowson9 and Ali Duarte-Garcia1, 1Mayo Clinic, Rochester, MN, 2ABC Medical Center, Ciudad de México, Federal District, Mexico, 3Vanderbilt University Medical Center, Nashville, 4Mayo Clinic, Rochester, 5Children’s National Medical Center, Washington D.C, 6Universidad Panamericana, Ciudad de México, Federal District, Mexico, 7Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico, 8Clínica Alemana de Santiago, Santiago, Chile, 9Mayo Clinic, Stewartvillle, MN

    Background/Purpose: Posterior reversible encephalopathy syndrome (PRES) is an underrecognized neuroradiologic complication of SLE, characterized by acute neurological symptoms and vasogenic edema on neuroimaging. Its precipitating…
  • Abstract Number: 1095 • ACR Convergence 2025

    Tolerance of non-TNF α treatments in patient with an inflammatory rheumatic (IRD) and autoimmune demyelinating diseases: French retrospective cases series

    dellal azeddine1, Jean-Guillaume Letarouilly2, Jacques Morel3, René-Marc Flipo4, Valerie Devauchelle5, richette pascal6, Philippe Dieude7, Hubert Marotte8, FELTEN Renaud9, LATOURTE Augustin10, CHEVET Baptiste11, HILLIQUIN Pascal12, SORDET Christelle9, DERNIS mmanuelle13, WENDLING Daniel14, Arsène Mekinian15, Nathalie BALLANDRAUD16, Christophe Richez17, TOURNADRE Anne18, salmon Jean -Hugues19, SAILLOT Carine20, kedra joanna21, nahon stephane22, LE GOFF Benoit23, Bruno Fautrel24, Francis BERENBAUM25, David SAADOUN26, PHAM Thao16 and SELLAM JEREMIE27, 1GHI LE RAINCY MONTFERMEIL, Montfermeil, France, 2Université de Lille, CHU Lille, Service de rhumatologie, Lille, France, LILLE, Nord-Pas-de-Calais, France, 3CHU and University of Montpellier, Montpellier, France, 4Université de Lille, CHU Lille, Service de rhumatologie, Lille, France, Lille, France, 5UBO, Brest, France, 6Rheumatology Department, Lariboisiere Hospital, Paris, Ile-de-France, France, 7Service de Rhumatologie, Hôpital Bichat APHP, Paris, Paris, Ile-de-France, France, 8INSERM 1059/University of Saint-Etienne, Saint-Etienne, France, 9Service de Rhumatologie, Centre de référence des maladies auto-immunes rares (RESO), Hôpitaux Universitaires de Strasbourg, Strasbourg, Strasbourg, Alsace, France, 10Rheumatology Department, Lariboisiere Hospital, Paris, France, 11CHU BREST, brest, Bretagne, France, 12CH SUD FRANCILIEN, PARIS, France, 13chu caen, CAEN, Haute-Normandie, France, 14CHU de Besançon, Besançon, Franche-Comte, France, 15Department of Internal Medicine, Inflammation-Immunopathology-Biotherapy Department (DMU i3), Saint-Antoine University Hospital, 75012 Paris, France, Paris, France, 16CHU MARSEILLE, marseille, Provence-Alpes-Cote d'Azur, France, 17Bordeaux University Hospital, Bordeaux, France, 18CHU CLERMONT, CLERMONT, Lorraine, France, 19CHU REIMS, REIMS, Champagne-Ardenne, France, 20CHU ORLEANS, ORLEANS, Pays de la Loire, France, 21Pitié-Salpêtrière Hospital, Rheumatology Department, APHP, Sorbonne University,, Paris, France, 22GHI LE RAINCY MONTFERMEIL, Montfermeil, Ile-de-France, France, 23CHU Nantes, Nantes, France, 24Sorbonne Université - APHP, Department of Rheumatology, Hôpital Pitié-Salpêtrière, Inserm UMRS 1136-5, PARIS, France, Paris, France, 25Sorbonne University/Inserm/AP-HP/4Moving Biotech, Paris, France, 26CHU LA PITIE SALPETRIERE, PARIS, Ile-de-France, France, 27Sorbonne Université, Inserm, Centre de Recherche Saint-Antoine, CRSA, F-75012 Paris, France, /Rheumatology Department, AP-HP Saint-Antoine Hospital, 184, rue du Faubourg Saint-Antoine, 75012, Paris, France., Paris, France

    Background/Purpose: The use of TNFα antagonist is not recommended if the patient have a suspicion or demyelinating diseases (DD) confirmed [1]. There are a few…
  • Abstract Number: 1378 • ACR Convergence 2025

    Prevalence of Central Nervous System Manifestations in Sjögren’s Disease

    Arun Varadhachary1, Ghaith Noaiseh2, Katherine Hammitt3, Julie Frantsve-Hawley3, Paula Barreras Cortes4, Shamik Bhattacharyya5, E. Sherwood Brown6, Drew Carey7, Robert Fox8, Brent Goodman9, Thomas Grader-Beck10, Janet Lewis11, Stephen Maitz12, Steven Mandel13, Jenifer McCombe14, Astrid Rasmussen15, George Sarka16, Daniel Wallace17, Frederick Vivino18, Rochelle Zak19, Nancy Carteron20, R Hal Scofield15 and Steven Carsons21, 1Washington University in St. Louis, St. Louis, MO, 2University of Kansas Medical Center, Kansas City, KS, 3Sjogren's Foundation, Reston, VA, 4Cedars Sinai, Los Angeles, CA, 5Brigham and Women's Hospital, Malden, MA, 6UT Southwestern Medical Center, Dallas, TX, 7Johns Hopkins University School of Medicine, Baltimore, MD, 8Rheumatology Clinic, San Diego, CA, 9HonorHealth, Scottsdale, AZ, 10Johns Hopkins, Reisterstown, MD, 11University of Virginia, Charlottesville, VA, 12U.S. Department of Veterans Affairs, Coatesville, PA, 13Donald and Barbara Zucker School of Medicine and Hofstra/Northwell, Hempstead, NY, 14University of Alberta, Edmonton, AB, Canada, 15Oklahoma Medical Research Foundation, Oklahoma City, OK, 16Cedars-Sinai Medical Center, Laguna Hills, CA, 17Cedars Sinai Medical Center, Studio City, CA, 18University of Pennsylvania, Bryn Mawr, PA, 19UCSF Health, San Francisco, CA, 20University of California, Berkeley & San Francisco, Angwin, CA, 21NYU Long Island School of Medicine, Mineola, NY

    Background/Purpose: Sjögren’s disease is a systemic autoimmune disorder with diverse clinical manifestations affecting multiple organ systems. While dry mouth, dry eyes, fatigue and pain are…
  • Abstract Number: 1164 • ACR Convergence 2024

    IVIG Treatment Duration in Immune-mediated Necrotizing Myopathy and a Possible Association of Vacuolar Changes with Black/African American Female Patients

    Asim Mohamed1, Liron Caplan2 and Melissa Griffith3, 1PGY5, Aurora, CO, 2Rocky Mountain Regional VAMC, Aurora, CO, 3University of Colorado, Aurora, CO

    Background/Purpose: Immune Mediated Necrotizing Myopathy (IMNM) is a debilitating but understudied entity.  Correlations of demographic and clinical features with pathological findings remain underexplored.  In addition,…
  • Abstract Number: 1227 • ACR Convergence 2024

    Longitudinal Patterns of Fibromyalgia Phenotypes in Patients with Systemic Lupus Erythematosus

    Brooke Cohen1, Philip Carlucci2, Kelly Corbitt3, Mala Masson4, Amit Saxena5, H Michael Belmont5, Chung-E Tseng6, Rachel Wu7, Hamleini Martinez7, George Kenefati7, Lisa Doan7, Jing Wang8, Kamil Barbour9, Heather Gold7, Jill Buyon10 and Peter Izmirly11, 1NYU Langone, NYC, NY, 2New York University School of Medicine, New York, NY, 3University of Miami Miller School of Medicine, El Portal, FL, 4NYU Langone Medical Center- Division of Rheumatology, New York, NY, 5NYU School of Medicine, New York, NY, 6NYU Langone Health, Flushing, NY, 7NYU Langone Health, NYC, 8NYU Langone Health, NYC, NY, 9CDC, Alpharetta, GA, 10NYU Grossman School of Medicine, New York, NY, 11New York University Grossman School of Medicine, New York, NY

    Background/Purpose: Fibromyalgia (FM) is a common comorbidity in patients with systemic lupus erythematosus (SLE) and a major contributor to poor health related quality of life.…
  • Abstract Number: 1276 • ACR Convergence 2024

    Therapeutic Drug Monitoring (TDM) of Rituximab to Predict Early B-Cell Repopulation in Children

    Rana Alsulami1, Bindiya Chugani2, Joley Johnstone2, Ann Yeh2, Floris Loeff3, Linda Hiraki2, Andrea Knight4, Deborah Levy2 and Ruud Verstegen2, 1University of Toronto, Toronto, ON, Canada, 2The Hospital for Sick Children, Toronto, ON, Canada, 3Sanquin Diagnostic Services, Amsterdam, Netherlands, 4Division of Rheumatology, The Hospital for Sick Children; Neurosciences and Mental Health, SickKids Research Institute; Department of Paediatrics, University of Toronto, Toronto, ON, Canada

    Background/Purpose: Rituximab is increasingly used in pediatric inflammatory diseases, with dosing extrapolated from adult data due to a lack of pediatric-specific pharmacokinetic (PK) information. Children…
  • Abstract Number: 1414 • ACR Convergence 2024

    Evidence-Based Guidelines for Sjögren’s Disease Peripheral Nervous System Manifestations

    Robert Fox1, Anahita Deboo2, Matthew Baker3, Stamatina Danielides4, Eduardo de Sousa5, Julie Frantsve Hawley6, Brent Goodman7, Katherine Hammitt6, Jennifer King8, Matt Makara6, Steven Mandel9, Ghaith Noaiseh10, Pantelis Pavlakis11, George Sarka12, Arun Varadhachary13, Daniel Wallace14, Robert Hal Scofield15, Nancy Carteron16 and Steven Carsons17, 1Rheumatology Clinic, San Diego, CA, 2Temple University, Philadelphia, 3Stanford University, Menlo Park, CA, 4Vcu, Glen Allen, VA, 5Mercy, Moore, OK, 6Sjogren's Foundation, Reston, VA, 7Mayo Clinic, Scottsdale, AZ, 8UCLA, Los Angeles, CA, 9Hofstra, Hempstead, 10University of Kansas Medical Center, Kansas City, KS, 11Hospital for Special Surgery, New York, NY, 12UCLA, Laguna Hills, CA, 13Washington University in St. Louis, St. Louis, MO, 14Cedars Sinai Medical Center, Studio City, CA, 15Oklahoma Medical Research Foundation, Oklahoma City, OK, 16University of California, Berkeley & San Francisco, Angwin, CA, 17NYU Long Island School of Medicine, Mineola, NY

    Background/Purpose: Peripheral Nervous System (PNS) manifestations occur frequently in Sjögren’s disease and can encompass mononeuropathy, polyneuropathy, and autonomic neuropathy. Guidance is needed for rheumatologists, neurologists,…
  • Abstract Number: 1420 • ACR Convergence 2024

    Alignment Between Rheumatology and Neurology of Nomenclature for Peripheral Nervous System Neuropathies

    Ghaith Noaiseh1, George Sarka2, Anahita Deboo3, Arun Varadhachary4, Robert Fox5, Matthew Baker6, Stamatina Danielides7, Eduardo de Sousa8, Julie Frantsve Hawley9, Brent Goodman10, Katherine Hammitt9, Jennifer King11, Steven Mandel12, Pantelis Pavlakis13, Daniel Wallace14, Robert Hal Scofield15, Nancy Carteron16 and Steven Carsons17, 1University of Kansas Medical Center, Kansas City, KS, 2UCLA, Laguna Hills, CA, 3Temple University, Philadelphia, 4Washington University in St. Louis, St. Louis, MO, 5Rheumatology Clinic, San Diego, CA, 6Stanford University, Menlo Park, CA, 7Vcu, Glen Allen, VA, 8Mercy, Moore, OK, 9Sjogren's Foundation, Reston, VA, 10Mayo Clinic, Scottsdale, AZ, 11UCLA, Los Angeles, CA, 12Hofstra, Hempstead, 13Hospital for Special Surgery, New York, NY, 14Cedars Sinai Medical Center, Studio City, CA, 15Oklahoma Medical Research Foundation, Oklahoma City, OK, 16University of California, Berkeley & San Francisco, Angwin, CA, 17NYU Long Island School of Medicine, Mineola, NY

    Background/Purpose: The Sjögren’s Foundation Clinical Practice Guidelines for Peripheral Nervous System (PNS) diagnosis, management and treatment in Sjögren’s brought to the fore a major issue…
  • Abstract Number: 2177 • ACR Convergence 2024

    CD59 Complement Membrane Regulator Deficiency: 12 Years of Clinical and Molecular Follow-up of 29 Patients

    Dror Mevorach, Netanel Karbian, Marian Zeibak and Adi Tabib, Hadassah-University Hospital, Jerusalem, Israel

    Background/Purpose: We have described in 2013, homozygous CD59-deficient children that manifest with recurrent peripheral neuropathy resembling Guillain-Barré syndrome (GBS), with hemolytic anemia and recurrent strokes.…
  • Abstract Number: 2420 • ACR Convergence 2024

    Blood Transcriptome Analysis Reveals Enhanced B Cell and Complement Cascade Signatures in Patients with Major Neuropsychiatric Systemic Lupus Erythematosus

    Dionysis Nikolopoulos1, George Sentis2, Jason Kitsos2, Panagiotis Garantziotis3, Noemin Kapsala2, antigoni Pieta2, Myrto Nikoloudaki4, Theodora Manolakou5, Sofia Flouda2, Ioannis Parodis6, Anastasia Filia2, George Bertsias7, Antonis Fanouriakis2 and Dimitrios Boumpas8, 1Karolinska Institutet and Karolinska University Hospital, Division of Rheumatology, Department of Medicine Solna, Stockholm, Sweden, 2National and Kapodistrian University of Athens, Athens, Greece, 3Department of Internal Medicine 3-Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany, Erlangen, Germany, 4Rheumatology and Clinical Immunology, University of Crete School of Medicine, Heraklion, Greece, Heraklion, Greece, 5Karolinska Institutet, Stockholm, Sweden, 6Karolinska Institutet, Karolinska University Hospital; Örebro University, Solna, Sweden, 7Laboratory of Rheumatology, Autoimmunity and Inflammation. University Hospital, Rheumatology, Clinical Immunology, Heraklion, Greece, 84th Department of Internal Medicine, "Attikon" University Hospital, Athens, Greece, Athens, Greece

    Background/Purpose: The molecular basis of neuropsychiatric systemic lupus erythematosus (NPSLE) remains elusive because of clinical heterogenicity, the complexity of pathophysiologic mechanisms involved and limited access…
  • Abstract Number: 2461 • ACR Convergence 2024

    Prevalence and Impact of Peripheral Neuropathy in SSc: A Frequent and Disabling Manifestation in SSc, and a Potential Surrogate Marker for Autonomic Neuropathy

    Begonya Alcacer-Pitarch1, marco di battista2, Anthony C. Redmond3, Anne-Maree Keenan4, Stefano Di Donato5, Francesco Del Galdo3 and Maya H. Buch6, 1Institute of Rheumatic and Musculoskeletal Medicine, Leeds, United Kingdom, 2Rheumatology Unit, University of Pisa, Pisa., Pisa., Italy, 3University of Leeds, Leeds, United Kingdom, 4School of Healthcare, university of leeds, leeds, United Kingdom, 5Leeds Institute of Rheumatic and Musculoskeletal Medicine, Chapel Allerton Hospital, Leeds, UK, Leeds, United Kingdom, 6Division of Musculoskeletal & Dermatological Sciences, University of Manchester, and NIHR Manchester Biomedical Research Centre, Manchester, United Kingdom

    Background/Purpose: SSc patients have high disability and low quality of life (QoL), driven partially by poor physical function (PF), Gastro Intestinal (GI) problems, digital ulcers…
  • Abstract Number: 2481 • ACR Convergence 2024

    General, Nervous System, Eye, and Skin Involvement in the Phase 3 Trial of Avacopan for the Treatment of ANCA-Associated Vasculitis

    Rula A. Hajj-Ali1, Duvuru Geetha2, Raashid Luqmani3, Christian Pagnoux4, Darcy Trimpe5, David Jayne6 and Peter Merkel7, and ADVOCATE Study Group, 1Cleveland Clinic, Cleveland, OH, 2Johns Hopkins University, Baltimore, MD, 3University of Oxford, Abingdon, United Kingdom, 4Mount Sinai Hospital, Toronto, ON, Canada, 5Amgen Inc., Thousand Oaks, CA, 6University of Cambridge, Cambridge, United Kingdom, 7University of Pennsylvania, Philadelphia, PA

    Background/Purpose: The most common types of ANCA-associated vasculitis, granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA), can affect a range of organs, including the kidneys,…
  • Abstract Number: 0311 • ACR Convergence 2024

    Investigation of Sarcoidosis-associated Neuropathy: Challenges with Diagnosis of Small Fiber Neuropathy

    Kristen Caldwell1, Sindhuja Koppu1, Kelly Gwathmey1, Aamer Syed1, Jordana Kron1, Thomas Iden1 and Huzaefah Syed2, 1Virginia Commonwealth University, Richmond, VA, 2Virginia Commonwealth University Medical Center, Richmond, VA

    Background/Purpose: Small fiber neuropathy (SFN) is an underrecognized complication of sarcoidosis which can significantly impair individuals’ physical functioning and quality of life. Diagnosis includes both…
  • Abstract Number: PP09 • ACR Convergence 2024

    Finding the Balance: Regaining My Strength While Living with Sjögren’s & POTS

    Robert Fearon, Sjögren's Foundation, Reston, VA

    Background/Purpose: Like many suffering from autoimmune diseases, my diagnosis was not straightforward and took nearly 13 years to get answers. I first started experiencing an…
  • Abstract Number: 0312 • ACR Convergence 2024

    The Use of Electromyography as a Screening Tool in Sarcoidosis-associated Neuropathy

    Kristen Caldwell1, Sindhuja Koppu1, Huzaefah Syed2, Aamer Syed1, Jordana Kron1, Thomas Iden1 and Kelly Gwathmey1, 1Virginia Commonwealth University, Richmond, VA, 2Virginia Commonwealth University Medical Center, Richmond, VA

    Background/Purpose: Small fiber neuropathy (SFN) is the most common peripheral nervous system manifestation of sarcoidosis. Diagnosis of SFN includes clinical evaluation, occasionally skin biopsy to…
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All abstracts accepted to PRYSM are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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