ACR Meeting Abstracts

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Abstracts tagged "neurology"

  • Abstract Number: 2049 • ACR Convergence 2025

    Descriptive Analysis of a Cohort of Neurosarcoidosis Mimics

    Shivani Rangaswamy1, Andrea Lopez1, Megumi Sugita1, Ethan Eyman1, Elijah Lackey1 and Jeffrey Shen2, 1Duke University Hospital, Durham, 2Division of Rheumatology and Immunology, Duke University Department of Medicine, Durham, NC

    Background/Purpose: Sarcoidosis is a granulomatous multi-system disease with nervous system involvement in 5-20% of patients. Diagnosis of neurosarcoidosis is challenging due to its broad spectrum…
  • Abstract Number: 2289 • ACR Convergence 2025

    Effects of Transcutaneous Auricular Vagus Nerve Stimulation on Disease Activity in Patients with Rheumatoid Arthritis: A Pilot Study

    Yuichiro Fujieda1, Kaoru Murakami2, Hiroki Tanaka2, Yuichi Kojima2, Yuki Kudo1, Kohei Karino1, Hiroyuki Nakamura1, Ryo Hisada1, Michihito Kono1, Masaaki Murakami2 and Tatsuya Atsumi1, 1Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan, 2Institute for Genetic Medicine, Graduate School of Medicine, Hokkaido University, Sapporo, Japan

    Background/Purpose: Vagus nerve stimulation (VNS) has emerged as a potential therapeutic strategy for inflammatory diseases by modulating inflammatory reflex pathways. Transcutaneous auricular vagus nerve stimulation…
  • Abstract Number: 2407 • ACR Convergence 2025

    Mapping Neurological Involvement, Regional Disparities, and Moderators of the Central Nervous System in Adult-Onset Systemic Lupus Erythematosus: A Global Systematic Review and Meta-Analysis

    Jorge Juan Fragío Gil1, Roxana González Mazario2, Pablo Martínez Calabuig3, Laura Salvador Maicas4, Mireia Sanmartin Martínez4, Iván Jesús Lorente Betanzos4, Amalia Rueda Cid4, Isabel Martínez Cordellat4, Juan José Lerma Garrido4 and Cristina Campos Fernández5, 1Hospital General Universitario, Valencia, Spain, 2Hospital General de Valencia, Valencia, Spain, 3Hospital General Universitario de Valencia, Spain/ Uversidad Catolica de Valencia San Vicente Martir, Valencia, Spain, Ontinyent, Spain, 4Hospital General Universitario de Valencia, Valencia, Comunidad Valenciana, Spain, 5Hospital General de Valencia, Valencia

    Background/Purpose: One common and clinically important form of systemic lupus erythematosus (SLE) is neuropsychiatric systemic lupus erythematosus (NPSLE). This systematic review and meta-analysis aimed to…
  • Abstract Number: 2481 • ACR Convergence 2024

    General, Nervous System, Eye, and Skin Involvement in the Phase 3 Trial of Avacopan for the Treatment of ANCA-Associated Vasculitis

    Rula A. Hajj-Ali1, Duvuru Geetha2, Raashid Luqmani3, Christian Pagnoux4, Darcy Trimpe5, David Jayne6 and Peter Merkel7, and ADVOCATE Study Group, 1Cleveland Clinic, Cleveland, OH, 2Johns Hopkins University, Baltimore, MD, 3University of Oxford, Abingdon, United Kingdom, 4Mount Sinai Hospital, Toronto, ON, Canada, 5Amgen Inc., Thousand Oaks, CA, 6University of Cambridge, Cambridge, United Kingdom, 7University of Pennsylvania, Philadelphia, PA

    Background/Purpose: The most common types of ANCA-associated vasculitis, granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA), can affect a range of organs, including the kidneys,…
  • Abstract Number: 0311 • ACR Convergence 2024

    Investigation of Sarcoidosis-associated Neuropathy: Challenges with Diagnosis of Small Fiber Neuropathy

    Kristen Caldwell1, Sindhuja Koppu1, Kelly Gwathmey1, Aamer Syed1, Jordana Kron1, Thomas Iden1 and Huzaefah Syed2, 1Virginia Commonwealth University, Richmond, VA, 2Virginia Commonwealth University Medical Center, Richmond, VA

    Background/Purpose: Small fiber neuropathy (SFN) is an underrecognized complication of sarcoidosis which can significantly impair individuals’ physical functioning and quality of life. Diagnosis includes both…
  • Abstract Number: PP09 • ACR Convergence 2024

    Finding the Balance: Regaining My Strength While Living with Sjögren’s & POTS

    Robert Fearon, Sjögren's Foundation, Reston, VA

    Background/Purpose: Like many suffering from autoimmune diseases, my diagnosis was not straightforward and took nearly 13 years to get answers. I first started experiencing an…
  • Abstract Number: 0312 • ACR Convergence 2024

    The Use of Electromyography as a Screening Tool in Sarcoidosis-associated Neuropathy

    Kristen Caldwell1, Sindhuja Koppu1, Huzaefah Syed2, Aamer Syed1, Jordana Kron1, Thomas Iden1 and Kelly Gwathmey1, 1Virginia Commonwealth University, Richmond, VA, 2Virginia Commonwealth University Medical Center, Richmond, VA

    Background/Purpose: Small fiber neuropathy (SFN) is the most common peripheral nervous system manifestation of sarcoidosis. Diagnosis of SFN includes clinical evaluation, occasionally skin biopsy to…
  • Abstract Number: 0363 • ACR Convergence 2024

    Comparative Risk of Demyelinating Diseases Among Patients on TNF-Alpha Inhibitors: A Cohort Study Using the TriNetX Database

    Rafal Ali1, Yurilu Gonzalez Moret2, Roua Hussein3 and Fabian Rodriguez4, 1Jefferson Einstein Philadelphia, Lansdale, PA, 2Jefferson Einstein Philadelphia, Philadelphia, PA, 3Al-Mustansiriyah University/ college of medicine, New York, NY, 4Jefferson Einstein Hospital, Philadelphia, PA

    Background/Purpose: TNF-alpha inhibitors are widely used in the field of rheumatology and have been linked to various possible adverse events, including demyelinating diseases. This association…
  • Abstract Number: 0844 • ACR Convergence 2024

    Effectiveness and Safety of the Recombinant Zoster Vaccine in Patients ≥18 Years of Age with Systemic Lupus Erythematosus or Multiple Sclerosis

    Sheryl Kluberg1, Sophie E. Mayer2, O’Mareen Spence3, Driss Oraichi4, Harry Seifert4, Omar Ali3, Huifeng Yun4, Andrew L. Simon5, Jenice S. Ko6, Caroline Hugh7, Meg Her7, Kathleen Shattuck7, Richard Platt8, Aziza Jamal-Allial9, Djeneba Audrey DJIBO10, Kimberly Daniels11, Qianli Ma12, Cheryl N McMahill-Walraven10, Rachel P. Ogilvie13, Kristin Palmsten14, Mano Selvan15, Najat Ziyadeh16, Alexis Ogdie17 and Michael George18, 1Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, 2Harvard Pilgrim Health Care Institute, Durham, 3GSK, Rockville, 4GSK, Rockville, MD, 5Harvard Pilgrim Healthcare Institute, Boston, MA, 6Harvard Pilgrim Health Care Ins􀆟tute, Boston, MA, 7Harvard Pilgrim Health Care Institute, Boston, MA, 8Harvard Pilgrim Health Care Institute / Harvard Medical School, Boston, MA, 9Carelon Research, Elevance Health, Newton, 10CVS Health, Blue Bell, 11Carelon Research, Elevance Health, Wilmington, 12Humana Healthcare Research, Inc., Louisville, 13Optum, Boston, MA, 14HealthPartners Institute, Minneapolis, 15Humana Healthcare Research, Sugar Land, Texas, 16Optum, Baltimore, MD, 17Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 18University of Pennsylvania, Philadelphia, PA

    Background/Purpose: The recombinant zoster vaccine (RZV) is US Food and Drug Administration-approved for the prevention of herpes zoster (HZ, shingles) in adults ≥50 years, and…
  • Abstract Number: 0926 • ACR Convergence 2024

    Macrophages and Nociceptor Neurons Form a Sentinel Unit Around Fenestrated Capillaries to Defend the Synovium from Systemic Challenges

    Tetsuo Hasegawa and Menna Clatworthy, University of Cambridge, Cambridge, United Kingdom

    Background/Purpose: A wide variety of systemic pathologies, including infectious and autoimmune diseases, are accompanied by joint pain or inflammation, often mediated by circulating immune complexes…
  • Abstract Number: 1092 • ACR Convergence 2024

    Chronic Kidney Disease Is Associated with Increased Glucose Uptake-associated Metabolic Activity of Visceral Adipose and Subcutaneous Adipose Tissue in Gout Patients

    Shunya Kaneshita1, Sho Fukui2, Soheil Niku3, KWANGHOON LEE4, Ernest Belezzuoli3, Robert Terkeltaub5 and Monica Guma6, 1UCSD, Miyazu city, Kyoto, Japan, 2Brigham and Women's Hospital, Brookline, MA, 3UCSD, La Jolla, 4UCSD, San Diego, CA, 5Retired, San Diego, CA, 6UCSD, La Jolla, CA

    Background/Purpose: Gout, a condition characterized by elevated uric acid levels, is linked to multiple complications, including coronary artery disease, hypertension, and type 2 diabetes mellitus.…
  • Abstract Number: 1093 • ACR Convergence 2024

    Risk of Dementia in Patients with Gout: Potential Impact of Survival Bias

    Joshua Baker1, Lindsay Helget2, chung-Chou Chang3, Bryant England2, Brian Coburn1, Harlan Sayles2, Punyasha Roul4 and Ted Mikuls2, 1University of Pennsylvania, Philadelphia, PA, 2University of Nebraska Medical Center, Omaha, NE, 3University of Pittsburgh, Pittsburgh, PA, 4UNMC, Omaha, NE

    Background/Purpose: Prior studies reported a lower risk of dementia among patients with gout suggesting that hyperuricemia might play a neuroprotective role. However, risk estimates for…
  • Abstract Number: 1164 • ACR Convergence 2024

    IVIG Treatment Duration in Immune-mediated Necrotizing Myopathy and a Possible Association of Vacuolar Changes with Black/African American Female Patients

    Asim Mohamed1, Liron Caplan2 and Melissa Griffith3, 1PGY5, Aurora, CO, 2Rocky Mountain Regional VAMC, Aurora, CO, 3University of Colorado, Aurora, CO

    Background/Purpose: Immune Mediated Necrotizing Myopathy (IMNM) is a debilitating but understudied entity.  Correlations of demographic and clinical features with pathological findings remain underexplored.  In addition,…
  • Abstract Number: 1227 • ACR Convergence 2024

    Longitudinal Patterns of Fibromyalgia Phenotypes in Patients with Systemic Lupus Erythematosus

    Brooke Cohen1, Philip Carlucci2, Kelly Corbitt3, Mala Masson4, Amit Saxena5, H Michael Belmont5, Chung-E Tseng6, Rachel Wu7, Hamleini Martinez7, George Kenefati7, Lisa Doan7, Jing Wang8, Kamil Barbour9, Heather Gold7, Jill Buyon10 and Peter Izmirly11, 1NYU Langone, NYC, NY, 2New York University School of Medicine, New York, NY, 3University of Miami Miller School of Medicine, El Portal, FL, 4NYU Langone Medical Center- Division of Rheumatology, New York, NY, 5NYU School of Medicine, New York, NY, 6NYU Langone Health, Flushing, NY, 7NYU Langone Health, NYC, 8NYU Langone Health, NYC, NY, 9CDC, Alpharetta, GA, 10NYU Grossman School of Medicine, New York, NY, 11New York University Grossman School of Medicine, New York, NY

    Background/Purpose: Fibromyalgia (FM) is a common comorbidity in patients with systemic lupus erythematosus (SLE) and a major contributor to poor health related quality of life.…
  • Abstract Number: 1276 • ACR Convergence 2024

    Therapeutic Drug Monitoring (TDM) of Rituximab to Predict Early B-Cell Repopulation in Children

    Rana Alsulami1, Bindiya Chugani2, Joley Johnstone2, Ann Yeh2, Floris Loeff3, Linda Hiraki2, Andrea Knight4, Deborah Levy2 and Ruud Verstegen2, 1University of Toronto, Toronto, ON, Canada, 2The Hospital for Sick Children, Toronto, ON, Canada, 3Sanquin Diagnostic Services, Amsterdam, Netherlands, 4Division of Rheumatology, The Hospital for Sick Children; Neurosciences and Mental Health, SickKids Research Institute; Department of Paediatrics, University of Toronto, Toronto, ON, Canada

    Background/Purpose: Rituximab is increasingly used in pediatric inflammatory diseases, with dosing extrapolated from adult data due to a lack of pediatric-specific pharmacokinetic (PK) information. Children…
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All abstracts accepted to PRYSM are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 6:00 PM CT on March 18. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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